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BIS
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ProShares UltraShort Nasdaq Biotechnology (BIS)

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$15.68
Last Close (24-hour delay)
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Upturn Advisory Summary

07/29/2025: BIS (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Analysis of Past Performance

Type ETF
Historic Profit -8.73%
Avg. Invested days 45
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 2.0
ETF Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 07/29/2025

Key Highlights

Volume (30-day avg) -
Beta -1.09
52 Weeks Range 13.56 - 25.71
Updated Date 06/29/2025
52 Weeks Range 13.56 - 25.71
Updated Date 06/29/2025

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ProShares UltraShort Nasdaq Biotechnology

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ETF Overview

overview logo Overview

ProShares UltraShort Nasdaq Biotechnology (BIS) seeks daily investment results, before fees and expenses, that correspond to two times the inverse (-2x) of the daily performance of the Nasdaq Biotechnology Index. It is designed for investors seeking to profit from a short-term decline in the biotechnology sector.

reliability logo Reputation and Reliability

ProShares is a well-known provider of leveraged and inverse ETFs with a generally solid reputation for providing products that track their stated objectives closely on a daily basis.

reliability logo Management Expertise

ProShares has a dedicated team with experience in managing complex ETF products, including leveraged and inverse strategies.

Investment Objective

overview logo Goal

To deliver two times the inverse of the daily performance of the Nasdaq Biotechnology Index.

Investment Approach and Strategy

Strategy: Inverse and leveraged, seeking to deliver -2x the daily return of the Nasdaq Biotechnology Index.

Composition Primarily holds financial instruments, such as swap agreements, to achieve its leveraged inverse objective. Does not directly hold the underlying stocks of the Nasdaq Biotechnology Index.

Market Position

Market Share: BIS holds a segment of the inverse/leveraged biotech ETF market; however, its specific market share fluctuates with AUM and competitive offerings.

Total Net Assets (AUM): 67860000

Competitors

overview logo Key Competitors

  • Direxion Daily S&P Biotech Bear 3X Shares (LABD)

Competitive Landscape

The competitive landscape consists of other leveraged and inverse biotechnology ETFs. BIS competes with LABD primarily. BIS's advantage lies in its focused objective to track -2x daily performance, while LABD seeks -3x. However, the higher leverage of LABD may attract some investors.

Financial Performance

Historical Performance: Historical performance is directly tied to the performance of the Nasdaq Biotechnology Index. Given its inverse nature, BIS will generally increase in value when the index decreases.

Benchmark Comparison: The effectiveness of BIS is gauged by how closely it tracks -2x the daily performance of the Nasdaq Biotechnology Index.

Expense Ratio: 0.95

Liquidity

Average Trading Volume

BIS's average trading volume is moderate, providing sufficient liquidity for most traders but large orders can still move the price.

Bid-Ask Spread

The bid-ask spread is generally reasonable, allowing for relatively efficient trading.

Market Dynamics

Market Environment Factors

BIS is affected by factors impacting the biotechnology sector, including FDA approvals, clinical trial results, and overall market sentiment towards healthcare and innovation.

Growth Trajectory

BIS's growth trajectory is inversely correlated to the biotechnology sector's performance. Changes to strategy are uncommon, as the focus is on maintaining the target leverage ratio.

Moat and Competitive Advantages

Competitive Edge

BIS offers a specific leveraged inverse exposure to the biotechnology sector. Its competitive advantage lies in its simplicity and directness in tracking the specified index. The fund offers a straightforward approach for traders looking to bet against the biotech industry in the short term. The disadvantage lies in the daily reset of leverage which can result in erosion of value over time.

Risk Analysis

Volatility

BIS experiences high volatility due to its leveraged nature. The fund is designed to amplify returns, it also magnifies losses.

Market Risk

BIS is subject to market risk associated with the biotechnology sector, including regulatory risks, clinical trial failures, and pricing pressures.

Investor Profile

Ideal Investor Profile

BIS is best suited for sophisticated investors and active traders with a short-term outlook and a strong understanding of leveraged and inverse ETFs. It is not suitable for long-term investors.

Market Risk

Best for active traders seeking short-term exposure to the inverse performance of the biotechnology sector.

Summary

ProShares UltraShort Nasdaq Biotechnology (BIS) is a leveraged inverse ETF designed for experienced traders seeking short-term profits from a declining biotech sector. It delivers -2x the daily performance of the Nasdaq Biotechnology Index, making it a risky but potentially rewarding option for those with a bearish outlook. The fund's high expense ratio and daily reset add to the complexity, making it unsuitable for passive, long-term investors. Investors should carefully consider their risk tolerance and understand the intricacies of leveraged inverse ETFs before investing.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • ProShares website
  • ETF.com
  • FactSet

Disclaimers:

The information provided is for informational purposes only and does not constitute financial advice. Investors should conduct their own due diligence and consult with a financial advisor before making investment decisions. Leveraged and inverse ETFs are complex instruments and should be used with caution.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About ProShares UltraShort Nasdaq Biotechnology

Exchange NASDAQ
Headquaters -
IPO Launch date -
CEO -
Sector -
Industry -
Full time employees -
Website
Full time employees -
Website

The fund invests in financial instruments that ProShare Advisors believes, in combination, should produce daily returns consistent with the Daily Target. The index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies. Under normal circumstances, the fund will obtain inverse leveraged exposure to at least 80% of its total assets in components of the index or in instruments with similar economic characteristics. The fund is non-diversified.