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SPDR® S&P Biotech ETF (XBI)



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Upturn Advisory Summary
07/09/2025: XBI (2-star) has a low Upturn Star Rating. Not recommended to BUY.
Analysis of Past Performance
Type ETF | Historic Profit 18.17% | Avg. Invested days 51 | Today’s Advisory Consider higher Upturn Star rating |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | ETF Returns Performance ![]() |
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Key Highlights
Volume (30-day avg) - | Beta 0.8 | 52 Weeks Range 66.65 - 105.45 | Updated Date 06/30/2025 |
52 Weeks Range 66.65 - 105.45 | Updated Date 06/30/2025 |
Upturn AI SWOT
SPDR® S&P Biotech ETF
ETF Overview
Overview
The SPDRu00ae S&P Biotech ETF (XBI) seeks to provide investment results that, before fees and expenses, correspond generally to the total return performance of the S&P Biotechnology Select Industry Index. It focuses on the biotechnology sector, offering exposure to a diverse range of companies involved in developing and manufacturing biotechnology products.
Reputation and Reliability
State Street Global Advisors (SSGA) is a well-established and reputable ETF issuer with a long track record in the financial industry.
Management Expertise
SSGA has extensive experience in managing ETFs across various sectors and asset classes, including biotechnology.
Investment Objective
Goal
The ETF aims to track the performance of the S&P Biotechnology Select Industry Index.
Investment Approach and Strategy
Strategy: The ETF uses a replication strategy, aiming to hold all the stocks in the S&P Biotechnology Select Industry Index in proportion to their weighting in the index.
Composition The ETF holds stocks of companies in the biotechnology sector, primarily in the United States.
Market Position
Market Share: XBI holds a substantial market share in the biotech ETF sector.
Total Net Assets (AUM): 7310000000
Competitors
Key Competitors
- iShares Biotechnology ETF (IBB)
- ARK Genomic Revolution ETF (ARKG)
- VanEck Biotech ETF (BBH)
Competitive Landscape
The biotech ETF industry is competitive, with several ETFs offering exposure to this sector. XBI's equal-weighted approach differentiates it from market-cap weighted ETFs like IBB. XBIu2019s equal weight design exposes investors to high volatility, but also leads to greater alpha generation when compared to IBB as it benefits more from positive earnings surprises from smaller companies. ARKG focuses on genomic revolution companies and is actively managed.
Financial Performance
Historical Performance: Historical performance data is available on various financial websites. [Data will vary based on date of retrieval]
Benchmark Comparison: The ETF's performance is compared to the S&P Biotechnology Select Industry Index.
Expense Ratio: 0.35
Liquidity
Average Trading Volume
The ETF has a high average trading volume, indicating good liquidity.
Bid-Ask Spread
The bid-ask spread is generally tight, reflecting its high liquidity.
Market Dynamics
Market Environment Factors
Factors influencing the ETF include FDA approvals, clinical trial results, regulatory changes, and overall market sentiment towards the biotechnology sector.
Growth Trajectory
The growth trajectory depends on the innovation and success of biotechnology companies, as well as broader economic and healthcare trends. Biotech is driven by innovation so rapid changes to sector holdings are likely in the future.
Moat and Competitive Advantages
Competitive Edge
XBI's competitive edge lies in its equal-weighted approach, offering broader exposure to smaller biotechnology companies compared to market-cap weighted ETFs. This strategy can potentially lead to higher growth but also increased volatility. State Street Global Advisors' reputation and extensive ETF management experience contribute to its appeal. The ETFu2019s low expense ratio compared to actively managed competitors adds to its attractiveness.
Risk Analysis
Volatility
The ETF exhibits high volatility due to the inherent risks associated with biotechnology companies, including clinical trial failures and regulatory hurdles.
Market Risk
The ETF is susceptible to market risk, particularly sentiment and events affecting the biotechnology sector.
Investor Profile
Ideal Investor Profile
The ETF is suitable for investors with a high-risk tolerance seeking exposure to the biotechnology sector.
Market Risk
This ETF is better suited for long-term investors who understand the biotech industry risks and are willing to accept volatility for potential growth.
Summary
The SPDRu00ae S&P Biotech ETF (XBI) offers investors exposure to the biotechnology sector through an equal-weighted approach that differentiates it from market-cap weighted peers. While the equal-weighting scheme adds to the ETFu2019s volatility, it also allows for better diversification and higher potential for gains. The fund's success is closely tied to the performance of its underlying biotech companies, making it a higher-risk but potentially high-reward investment. Investors should carefully consider their risk tolerance and conduct thorough due diligence before investing. State Street Global Advisors' reputation and management expertise provides additional support for the ETF's sustainability.
Peer Comparison
Sources and Disclaimers
Data Sources:
- State Street Global Advisors (SSGA) website
- Yahoo Finance
- ETF.com
- Morningstar
Disclaimers:
The information provided is for informational purposes only and should not be considered investment advice. Investment decisions should be made based on individual circumstances and after consulting with a qualified financial advisor. Past performance is not indicative of future results. Market share data is estimated and may not be precise.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About SPDR® S&P Biotech ETF
Exchange NYSE ARCA | Headquaters - | ||
IPO Launch date - | CEO - | ||
Sector - | Industry - | Full time employees - | Website |
Full time employees - | Website |
In seeking to track the performance of the S&P Biotechnology Select Industry Index (the index), the fund employs a sampling strategy. It generally invests substantially all, but at least 80%, of its total assets in the securities comprising the index. The index represents the biotechnology segment of the S&P Total Market Index (S&P TMI).

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