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XBI
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SPDR® S&P Biotech ETF (XBI)

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$93.74
Last Close (24-hour delay)
Profit since last BUY11.26%
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BUY since 70 days
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Upturn Advisory Summary

09/16/2025: XBI (2-star) has a low Upturn Star Rating. Not recommended to BUY.

Upturn Star Rating

rating

Below Average Performance

These Stocks/ETFs, based on Upturn Advisory, often underperform the market, warranting careful consideration before investing.

Analysis of Past Performance

Type ETF
Historic Profit 26.06%
Avg. Invested days 60
Today’s Advisory Consider higher Upturn Star rating
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 4.0
ETF Returns Performance Upturn Returns Performance 4.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 09/16/2025

Key Highlights

Volume (30-day avg) -
Beta 0.8
52 Weeks Range 66.65 - 105.45
Updated Date 06/30/2025
52 Weeks Range 66.65 - 105.45
Updated Date 06/30/2025

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SPDR® S&P Biotech ETF

stock logo

ETF Overview

overview logo Overview

The SPDRu00ae S&P Biotech ETF (XBI) seeks to provide investment results that, before fees and expenses, correspond generally to the total return performance of the S&P Biotechnology Select Industry Index. It focuses on the biotechnology sector, allocating assets primarily to companies involved in the research, development, manufacturing, and marketing of biotechnology products.

reliability logo Reputation and Reliability

State Street Global Advisors (SSGA) is a well-established and reputable ETF provider with a long track record of managing index-tracking funds.

reliability logo Management Expertise

SSGA has extensive experience in managing index funds and employs a team of professionals with expertise in the ETF market.

Investment Objective

overview logo Goal

To provide investment results that, before fees and expenses, correspond generally to the total return performance of the S&P Biotechnology Select Industry Index.

Investment Approach and Strategy

Strategy: The ETF employs a replication strategy, attempting to hold all of the stocks in the S&P Biotechnology Select Industry Index in proportion to their weighting in the index.

Composition The ETF holds a portfolio of common stocks of U.S. biotechnology companies.

Market Position

Market Share: XBI holds a significant market share within the biotechnology ETF sector, reflecting its popularity among investors seeking exposure to this industry.

Total Net Assets (AUM): 7240000000

Competitors

overview logo Key Competitors

  • iShares Biotechnology ETF (IBB)
  • ARK Genomic Revolution ETF (ARKG)
  • Invesco Dynamic Biotechnology & Genome ETF (PBE)

Competitive Landscape

The biotechnology ETF sector is competitive, with IBB holding a larger market share than XBI; ARKG focuses on genomic companies. XBI's equal-weight approach differentiates it from IBB's market-cap-weighted index, potentially offering better diversification. However, IBB's larger AUM and greater liquidity may be advantageous for some investors.

Financial Performance

Historical Performance: Past performance is not indicative of future results. Investors should consider performance over various time horizons.

Benchmark Comparison: The ETF's performance should be compared to the S&P Biotechnology Select Industry Index to assess its tracking efficiency.

Expense Ratio: 0.35

Liquidity

Average Trading Volume

XBI's average trading volume is high, indicating strong liquidity and ease of trading for investors.

Bid-Ask Spread

The bid-ask spread is typically tight, reflecting good liquidity and lower transaction costs for investors.

Market Dynamics

Market Environment Factors

Economic indicators, sector growth prospects, regulatory changes, and scientific breakthroughs in biotechnology significantly influence XBI's performance.

Growth Trajectory

XBI's growth trajectory depends on the overall performance of the biotechnology sector, which is driven by innovation, regulatory approvals, and market demand for new therapies; there have been no recent major changes to the fund's strategy or holdings.

Moat and Competitive Advantages

Competitive Edge

XBI's competitive edge lies in its equal-weighting methodology, which provides more balanced exposure to biotechnology companies, including smaller firms with high growth potential. This approach reduces the influence of larger, more established companies and potentially enhances diversification. Its low expense ratio compared to some active ETFs is an additional competitive advantage. The ETFu2019s pure play focus on biotech provides specific sector access.

Risk Analysis

Volatility

XBI is subject to high volatility due to the inherent risks of the biotechnology sector, including clinical trial failures, regulatory hurdles, and patent expirations.

Market Risk

Market risk is a primary concern due to XBI's concentration in the biotechnology sector, which is sensitive to economic cycles, interest rate changes, and investor sentiment; single stock risk is mitigated by holding all components of the index.

Investor Profile

Ideal Investor Profile

The ideal investor for XBI is someone who seeks exposure to the biotechnology sector, is comfortable with high volatility, and has a long-term investment horizon.

Market Risk

XBI is suitable for investors seeking long-term capital appreciation through exposure to the biotechnology sector, with a willingness to accept high volatility.

Summary

The SPDRu00ae S&P Biotech ETF (XBI) offers investors exposure to the biotechnology sector through an equal-weighted index-tracking approach. XBI's investment objective mirrors the performance of the S&P Biotechnology Select Industry Index, providing broad diversification and focused access to US biotech companies. The fundu2019s equal weighting mitigates concentration risk, allowing smaller companies greater influence. XBI's volatile and sector-specific nature makes it most suitable for long-term investors comfortable with potential market fluctuations and its relatively low expense ratio makes it favorable compared to other biotechnology related funds.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • State Street Global Advisors (SSGA) Website
  • ETF.com
  • Morningstar
  • Bloomberg

Disclaimers:

The data and analysis provided are for informational purposes only and should not be considered investment advice. Investors should conduct their own research and consult with a qualified financial advisor before making any investment decisions. Past performance is not indicative of future results. Market share figures are estimates and may vary based on source.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About SPDR® S&P Biotech ETF

Exchange NYSE ARCA
Headquaters -
IPO Launch date -
CEO -
Sector -
Industry -
Full time employees -
Website
Full time employees -
Website

In seeking to track the performance of the S&P Biotechnology Select Industry Index (the index), the fund employs a sampling strategy. It generally invests substantially all, but at least 80%, of its total assets in the securities comprising the index. The index represents the biotechnology segment of the S&P Total Market Index (S&P TMI).