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SPDR® S&P Biotech ETF (XBI)

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Upturn Advisory Summary
02/26/2026: XBI (5-star) is a STRONG-BUY. BUY since 182 days. Simulated Profits (52.08%). Updated daily EoD!
Key Highlights
Volume (30-day avg) - | Beta 0.8 | 52 Weeks Range 66.65 - 105.45 | Updated Date 06/30/2025 |
52 Weeks Range 66.65 - 105.45 | Updated Date 06/30/2025 |
Upturn AI SWOT
SPDR® S&P Biotech ETF
ETF Overview
Overview
The SPDRu00ae S&P Biotech ETF (XBI) is an investment fund that seeks to track the performance of the S&P Biotechnology Select Industry Index. It invests in companies involved in the biotechnology sector, focusing on drug discovery, development, and commercialization.
Reputation and Reliability
State Street Global Advisors (SSGA) is a well-established and reputable asset manager with a long history in the ETF industry, known for its broad range of index-tracking products and institutional expertise.
Management Expertise
SSGA has extensive experience in managing passive index funds and ETFs, leveraging sophisticated systems and a deep understanding of index construction and replication.
Investment Objective
Goal
To provide investors with exposure to the biotechnology industry by tracking the S&P Biotechnology Select Industry Index.
Investment Approach and Strategy
Strategy: The ETF aims to replicate the performance of its underlying index, the S&P Biotechnology Select Industry Index, which is an equal-weighted index.
Composition The ETF primarily holds common stocks of companies in the biotechnology industry.
Market Position
Market Share: XBI is a significant player within the US biotech ETF landscape, though its exact market share can fluctuate with market dynamics and overall AUM.
Total Net Assets (AUM): 10885000000
Competitors
Key Competitors
- iShares Biotechnology ETF (IBB)
- VanEck Biotech ETF (BBH)
- ARK Genomic Revolution ETF (ARKG)
Competitive Landscape
The biotech ETF market is competitive, with several established players offering similar exposure. XBI's equal-weighting strategy differentiates it from market-cap weighted competitors like IBB, potentially offering broader diversification within the sector. However, its equal-weighting can also lead to higher volatility and a greater impact from smaller, less established companies.
Financial Performance
Historical Performance: [object Object]
Benchmark Comparison: Historically, XBI has often outperformed its benchmark index on a risk-adjusted basis due to its equal-weighting methodology, which allows smaller companies to have a greater impact than they would in a market-cap weighted index. However, this can also lead to higher volatility.
Expense Ratio: 0.0035
Liquidity
Average Trading Volume
The ETF exhibits strong liquidity with a high average daily trading volume, facilitating efficient buying and selling.
Bid-Ask Spread
The bid-ask spread for XBI is typically narrow, indicating low trading costs for investors.
Market Dynamics
Market Environment Factors
The biotechnology sector is influenced by factors such as FDA approvals, patent expirations, research and development breakthroughs, government regulations, and overall economic health. XBI's performance is directly tied to these dynamics.
Growth Trajectory
The biotech sector has shown consistent long-term growth driven by innovation and an aging global population. XBI's strategy, which includes a broad range of companies, allows it to capture growth across various sub-sectors within biotechnology. Its holdings are regularly rebalanced to maintain the equal-weighting methodology.
Moat and Competitive Advantages
Competitive Edge
XBI's primary competitive edge lies in its equal-weighting methodology, which provides broader exposure to the biotechnology sector compared to market-cap weighted indices. This allows investors to participate in the growth of smaller, emerging biotech companies that might be overlooked in larger indices. Its status as a prominent ETF from a major issuer also contributes to its market recognition and liquidity.
Risk Analysis
Volatility
The SPDRu00ae S&P Biotech ETF exhibits higher volatility compared to broader market ETFs due to the inherent risks associated with the biotechnology sector, including clinical trial failures and regulatory hurdles.
Market Risk
Specific market risks for XBI include the high failure rate of drug development, intense competition, stringent regulatory environments, and the speculative nature of many biotech companies.
Investor Profile
Ideal Investor Profile
The ideal investor for XBI is one with a higher risk tolerance who seeks concentrated exposure to the biotechnology sector and believes in the long-term growth potential of innovation in this industry.
Market Risk
XBI is generally more suitable for long-term investors who understand and can tolerate the sector's inherent volatility, rather than for short-term traders or risk-averse investors.
Summary
The SPDRu00ae S&P Biotech ETF (XBI) offers targeted exposure to the dynamic biotechnology sector through an equal-weighted index strategy. While its equal-weighting provides broader diversification within the sector, it also contributes to higher volatility. With substantial assets under management and strong liquidity, XBI is a significant player in the biotech ETF space. It is best suited for investors with a higher risk tolerance seeking long-term growth in biotech innovation.
Similar ETFs
Sources and Disclaimers
Data Sources:
- State Street Global Advisors (SSGA) Official Website
- S&P Dow Jones Indices
- Financial Data Providers (e.g., Morningstar, Bloomberg - specific data points may vary)
Disclaimers:
This information is for illustrative purposes only and should not be considered investment advice. ETF performance can be volatile, and investors may lose money. Past performance is not indicative of future results. Investors should consult with a qualified financial advisor before making investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About SPDR® S&P Biotech ETF
Exchange NYSE ARCA | Headquaters - | ||
IPO Launch date - | CEO - | ||
Sector - | Industry - | Full time employees - | Website |
Full time employees - | Website | ||
In seeking to track the performance of the S&P Biotechnology Select Industry Index (the index), the fund employs a sampling strategy. It generally invests substantially all, but at least 80%, of its total assets in the securities comprising the index. The index represents the biotechnology segment of the S&P Total Market Index (S&P TMI).

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