XBI
XBI 4-star rating from Upturn Advisory

SPDR® S&P Biotech ETF (XBI)

SPDR® S&P Biotech ETF (XBI) 4-star rating from Upturn Advisory
$120.01
Last Close (24-hour delay)
Today's Top Performer logo Top performer
Profit since last BUY42.48%
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Strong Buy
BUY since 136 days
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Upturn Advisory Summary

12/18/2025: XBI (4-star) is a STRONG-BUY. BUY since 136 days. Simulated Profits (42.48%). Updated daily EoD!

Upturn Star Rating

Upturn 4 star rating for performance

Above Average Performance

These Stocks/ETFs, based on Upturn Advisory, frequently surpass the market, reflecting reliable and trustworthy advice.

Analysis of Past Performance

Type ETF
Historic Profit 61.43%
Avg. Invested days 74
Today’s Advisory Strong Buy
Upturn Star Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 4.0
ETF Returns Performance Upturn Returns Performance icon 5.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 12/18/2025

Key Highlights

Volume (30-day avg) -
Beta 0.8
52 Weeks Range 66.65 - 105.45
Updated Date 06/30/2025
52 Weeks Range 66.65 - 105.45
Updated Date 06/30/2025

Icon representing Upturn AI-generated SWOT analysis summary Upturn AI SWOT

SPDR® S&P Biotech ETF

SPDR® S&P Biotech ETF(XBI) company logo displayed in Upturn AI summary

ETF Overview

overview logo Overview

The SPDRu00ae S&P Biotech ETF (XBI) seeks to track the S&P Biotechnology Select Industry Index. It provides exposure to a broad range of biotechnology companies, including those involved in drug discovery, development, and manufacturing. The ETF's investment strategy focuses on companies that are part of the biotechnology and pharmaceutical sectors.

Reputation and Reliability logo Reputation and Reliability

State Street Global Advisors (SSGA) is a leading global asset manager and the sponsor of the SPDR ETFs. SSGA has a long-standing reputation for reliability and expertise in the exchange-traded fund market.

Leadership icon representing strong management expertise and executive team Management Expertise

SSGA employs experienced investment professionals and utilizes a passive management approach, aiming to replicate the performance of its underlying index.

Investment Objective

Icon representing investment goals and financial objectives Goal

To provide investors with a diversified investment in the biotechnology sector.

Investment Approach and Strategy

Strategy: The ETF aims to track the S&P Biotechnology Select Industry Index, which is an equal-weighted index. This means that each constituent company has a similar weighting in the index, regardless of its market capitalization.

Composition The ETF primarily holds common stocks of companies operating in the biotechnology industry. These companies can range from small-cap to large-cap, with a focus on those engaged in the research, development, and commercialization of pharmaceuticals and medical treatments.

Market Position

Market Share: As of recent data, XBI holds a significant position within the biotechnology ETF sector, though specific market share figures fluctuate.

Total Net Assets (AUM): 8000000000

Competitors

Key Competitors logo Key Competitors

  • iShares Biotechnology ETF (IBB)
  • ARK Genomic Revolution ETF (ARKG)

Competitive Landscape

The biotechnology ETF market is competitive, with several large players offering similar exposure. XBI's equal-weighting strategy is a key differentiator from market-cap-weighted ETFs like IBB. ARKG offers a more actively managed, thematic approach. XBI's advantage lies in its broad diversification and equal weighting, which can provide exposure to smaller, potentially faster-growing companies. A disadvantage might be its susceptibility to significant price swings due to its equal-weighting methodology.

Financial Performance

Historical Performance: The ETF has exhibited strong performance in periods of biotech sector growth, but also experienced significant drawdowns during market corrections. Past performance is not indicative of future results.

Benchmark Comparison: XBI aims to track the S&P Biotechnology Select Industry Index and generally performs in line with its benchmark, with minor tracking differences due to expenses.

Expense Ratio: 0.0035

Liquidity

Average Trading Volume

The SPDRu00ae S&P Biotech ETF generally exhibits high average trading volume, indicating good liquidity for investors.

Bid-Ask Spread

The bid-ask spread for XBI is typically tight, reflecting its high trading volume and making it cost-effective to trade.

Market Dynamics

Market Environment Factors

The biotech sector is influenced by factors such as clinical trial success rates, regulatory approvals (e.g., FDA), patent expirations, government healthcare policy, and innovation in drug discovery. Economic conditions can also impact investor sentiment towards riskier, growth-oriented sectors like biotech.

Growth Trajectory

The biotech sector has shown a consistent long-term growth trajectory driven by advancements in science and an aging global population. XBI's strategy of providing broad exposure allows it to participate in this growth across various sub-segments of the industry.

Moat and Competitive Advantages

Competitive Edge

XBI's primary competitive advantage is its equal-weighting methodology, which ensures broad exposure to a diverse range of biotechnology companies, including smaller, emerging players that might be underrepresented in market-cap-weighted indices. This diversification can mitigate the impact of any single company's performance and offers investors access to the full spectrum of innovation within the biotech landscape.

Risk Analysis

Volatility

The SPDRu00ae S&P Biotech ETF is known for its high historical volatility, reflecting the inherent risks and speculative nature of the biotechnology sector.

Market Risk

Specific market risks include the potential for failed clinical trials, adverse regulatory decisions, intense competition, patent challenges, and shifts in healthcare policy. The biotech sector is also sensitive to broader market sentiment towards growth and innovation stocks.

Investor Profile

Ideal Investor Profile

The ideal investor for XBI is one with a high-risk tolerance, a long-term investment horizon, and a strong belief in the growth potential of the biotechnology sector. Investors should be comfortable with significant price fluctuations.

Market Risk

This ETF is best suited for investors seeking aggressive growth opportunities and who are willing to accept higher levels of risk and volatility. It is generally not recommended for risk-averse investors or those with very short-term investment goals.

Summary

The SPDRu00ae S&P Biotech ETF (XBI) offers diversified exposure to the biotechnology sector through an equal-weighted index. Its broad holdings and focus on innovation make it attractive for investors with a high-risk tolerance and long-term outlook. While it offers significant growth potential, it is also characterized by high volatility and sector-specific risks. XBI competes in a crowded ETF space, with its equal-weighting strategy as a key differentiator.

Similar ETFs

Sources and Disclaimers

Data Sources:

  • State Street Global Advisors (SSGA) Website
  • Financial Data Aggregators (e.g., Morningstar, ETF.com)

Disclaimers:

This JSON output is for informational purposes only and does not constitute financial advice. Data is subject to change and may not be exhaustive. Investors should conduct their own due diligence before making investment decisions.

Information icon for Upturn AI Summarization accuracy disclaimer AI Summarization is directionally correct and might not be accurate.

Information icon for Upturn AI Summarization data freshness disclaimer Summarized information shown could be a few years old and not current.

Information icon warning about Upturn AI Fundamental Rating based on potentially old data Fundamental Rating based on AI could be based on old data.

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About SPDR® S&P Biotech ETF

Exchange NYSE ARCA
Headquaters -
IPO Launch date -
CEO -
Sector -
Industry -
Full time employees -
Website
Full time employees -
Website

In seeking to track the performance of the S&P Biotechnology Select Industry Index (the index), the fund employs a sampling strategy. It generally invests substantially all, but at least 80%, of its total assets in the securities comprising the index. The index represents the biotechnology segment of the S&P Total Market Index (S&P TMI).