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XBI
Upturn stock rating

SPDR® S&P Biotech ETF (XBI)

Upturn stock rating
$110.96
Last Close (24-hour delay)
Profit since last BUY31.73%
upturn advisory
Strong Buy
BUY since 101 days
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Upturn Advisory Summary

10/29/2025: XBI (3-star) is a STRONG-BUY. BUY since 101 days. Simulated Profits (31.73%). Updated daily EoD!

Upturn Star Rating

rating

Moderate Performance

These Stocks/ETFs, based on Upturn Advisory, typically align with the market average, offering steady but unremarkable returns.

Analysis of Past Performance

Type ETF
Historic Profit 49.25%
Avg. Invested days 67
Today’s Advisory Strong Buy
Upturn Star Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance 4.0
ETF Returns Performance Upturn Returns Performance 5.0
Upturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulation Last Close 10/29/2025

Key Highlights

Volume (30-day avg) -
Beta 0.8
52 Weeks Range 66.65 - 105.45
Updated Date 06/30/2025
52 Weeks Range 66.65 - 105.45
Updated Date 06/30/2025

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SPDR® S&P Biotech ETF

stock logo

ETF Overview

overview logo Overview

The SPDRu00ae S&P Biotech ETF (XBI) seeks to provide investment results that, before fees and expenses, correspond generally to the total return performance of the S&P Biotechnology Select Industry Index. It focuses on the biotechnology sector, utilizing a full replication strategy to hold all or substantially all of the component securities of the index.

reliability logo Reputation and Reliability

State Street Global Advisors (SSGA) is a well-established and reputable ETF provider with a long track record.

reliability logo Management Expertise

SSGA has extensive experience in managing index-tracking ETFs, including those focused on specific sectors like biotechnology.

Investment Objective

overview logo Goal

To provide investment results that correspond generally to the total return performance of the S&P Biotechnology Select Industry Index.

Investment Approach and Strategy

Strategy: Tracks the S&P Biotechnology Select Industry Index using a full replication strategy.

Composition Primarily holds stocks of US biotechnology companies.

Market Position

Market Share: XBI holds a significant market share within the biotechnology ETF sector.

Total Net Assets (AUM): 7330000000

Competitors

overview logo Key Competitors

  • iShares Biotechnology ETF (IBB)
  • ARK Genomic Revolution ETF (ARKG)
  • VanEck Biotech ETF (BBH)

Competitive Landscape

The biotechnology ETF market is competitive, with XBI, IBB, and ARKG being major players. XBI's equal-weighting strategy offers diversification, while IBB's market-cap weighting favors larger companies. ARKG offers exposure to innovative genomic companies but at a higher risk. XBI may provide exposure to smaller and mid-cap biotech firms, potentially offering higher growth but also higher volatility.

Financial Performance

Historical Performance: Historical performance data needs to be sourced directly from financial data providers. The data would be presented in a structured array format here.

Benchmark Comparison: Benchmark comparison data needs to be sourced directly from financial data providers and would be presented as a structured array.

Expense Ratio: 0.035

Liquidity

Average Trading Volume

XBI exhibits high liquidity due to its large AUM and popularity, allowing for easy buying and selling of shares.

Bid-Ask Spread

XBI typically has a tight bid-ask spread, indicating lower transaction costs for investors.

Market Dynamics

Market Environment Factors

Economic conditions, FDA regulations, clinical trial results, and technological advancements significantly affect XBI's performance.

Growth Trajectory

XBI's growth trajectory is tied to the overall health of the biotechnology sector and the success of its constituent companies.

Moat and Competitive Advantages

Competitive Edge

XBI's primary competitive advantage is its equal-weighting methodology, which provides broader exposure to smaller and mid-cap biotechnology companies. This contrasts with market-cap-weighted ETFs that are heavily influenced by larger companies. The equal-weight strategy potentially offers higher growth prospects but also increases volatility. XBI's lower expense ratio compared to some actively managed biotech ETFs also makes it attractive to cost-conscious investors.

Risk Analysis

Volatility

XBI can exhibit high volatility due to the inherent risks associated with the biotechnology sector, including clinical trial failures and regulatory hurdles.

Market Risk

XBI is subject to market risk, as the value of its holdings can fluctuate based on overall market conditions and investor sentiment towards the biotechnology sector.

Investor Profile

Ideal Investor Profile

XBI is suitable for investors seeking exposure to the biotechnology sector and willing to accept a higher level of risk. Investors who believe in the long-term growth potential of biotech and are comfortable with volatility may find XBI appealing.

Market Risk

XBI is best suited for long-term investors with a higher risk tolerance, rather than active traders looking for short-term gains.

Summary

The SPDRu00ae S&P Biotech ETF (XBI) offers investors diversified exposure to the US biotechnology sector. Its equal-weighting methodology provides broader exposure than market-cap-weighted funds, potentially leading to higher growth but also increased volatility. It is a cost-effective option for investors seeking to capitalize on the long-term growth potential of biotechnology. However, investors should be aware of the inherent risks associated with the sector, including clinical trial failures and regulatory changes.

Similar ETFs

Sources and Disclaimers

Data Sources:

  • State Street Global Advisors (SSGA), ETF.com, Bloomberg, Morningstar

Disclaimers:

The data and analysis provided are for informational purposes only and do not constitute financial advice. Investors should conduct their own research and consult with a financial advisor before making any investment decisions. Market share data is estimated and may vary depending on the source.

Upturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About SPDR® S&P Biotech ETF

Exchange NYSE ARCA
Headquaters -
IPO Launch date -
CEO -
Sector -
Industry -
Full time employees -
Website
Full time employees -
Website

In seeking to track the performance of the S&P Biotechnology Select Industry Index (the index), the fund employs a sampling strategy. It generally invests substantially all, but at least 80%, of its total assets in the securities comprising the index. The index represents the biotechnology segment of the S&P Total Market Index (S&P TMI).