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ABOS 1-star rating from Upturn Advisory
Acumen Pharmaceuticals Inc (ABOS) company logo

Acumen Pharmaceuticals Inc (ABOS)

Acumen Pharmaceuticals Inc (ABOS) 1-star rating from Upturn Advisory
$2.02
Last Close (24-hour delay)
Profit since last BUY-4.72%
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Upturn Advisory Summary

01/02/2026: ABOS (1-star) has a low Upturn Star Rating. Not recommended to BUY.

Upturn Star Rating

Upturn 1 star rating for performance

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

2 star rating from financial analysts

5 Analysts rated it

Limited analyst coverage, niche firm, research info may be scarce.

1 Year Target Price $6.4

1 Year Target Price $6.4

Analysts Price Target For last 52 week
$6.4 Target price
52w Low $0.86
Current$2.02
52w High $2.46

Analysis of Past Performance

Type Stock
Historic Profit -41.49%
Avg. Invested days 35
Today’s Advisory Consider higher Upturn Star rating
Upturn Star Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 2.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 01/02/2026

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 122.36M USD
Price to earnings Ratio -
1Y Target Price 6.4
Price to earnings Ratio -
1Y Target Price 6.4
Volume (30-day avg) 5
Beta 0.25
52 Weeks Range 0.85 - 2.46
Updated Date 01/4/2026
52 Weeks Range 0.85 - 2.46
Updated Date 01/4/2026
Dividends yield (FY) -
Basic EPS (TTM) -2.21

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -42.23%
Return on Equity (TTM) -85.93%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 26585318
Price to Sales(TTM) 538.78
Enterprise Value 26585318
Price to Sales(TTM) 538.78
Enterprise Value to Revenue 89.67
Enterprise Value to EBITDA -0.6
Shares Outstanding 60573425
Shares Floating 35610511
Shares Outstanding 60573425
Shares Floating 35610511
Percent Insiders 6.84
Percent Institutions 64.73

Icon representing Upturn AI-generated SWOT analysis summary Upturn AI SWOT

Acumen Pharmaceuticals Inc

Acumen Pharmaceuticals Inc(ABOS) company logo displayed in Upturn AI summary

Company Overview

Company history and background logo History and Background

Acumen Pharmaceuticals Inc. is a clinical-stage biopharmaceutical company focused on developing novel therapies for neurodegenerative diseases. Founded in [Founding Year - placeholder, as specific year not publicly available], the company's primary focus has been on advancing its lead candidate, ACU193, for the treatment of Alzheimer's disease. Significant milestones include successful completion of Phase 1 trials and commencement of Phase 2 trials for ACU193. The company has evolved by strategically focusing its pipeline on areas with high unmet medical need within the neurological space.

Company business area logo Core Business Areas

  • Neurodegenerative Disease Therapeutics: Development and commercialization of innovative therapies targeting the underlying mechanisms of neurodegenerative diseases, with a primary focus on Alzheimer's disease.

leadership logo Leadership and Structure

Acumen Pharmaceuticals Inc. is led by a team of experienced professionals in drug development and the pharmaceutical industry. [Specific leadership names and titles would be inserted here based on publicly available information, e.g., CEO, CSO, CFO, Board of Directors. The organizational structure is typical of a biopharmaceutical company, with departments dedicated to research and development, clinical operations, regulatory affairs, and corporate functions.]

Top Products and Market Share

Product Key Offerings logo Key Offerings

  • Product Name 1: [object Object]

Market Dynamics

industry overview logo Industry Overview

The neurodegenerative disease therapeutics market, particularly for Alzheimer's disease, is characterized by significant unmet medical needs and substantial research investment. It is a highly competitive and rapidly evolving field, with a focus on disease-modifying therapies that can slow or halt disease progression, rather than just managing symptoms. The market is driven by an aging global population and increasing prevalence of these conditions.

Positioning

Acumen Pharmaceuticals Inc. is positioned as a clinical-stage biopharmaceutical company with a novel approach to targeting a specific pathogenic species (amyloid-beta oligomers) in Alzheimer's disease. Their competitive advantage lies in the unique mechanism of action of ACU193 and its potential to offer a distinct therapeutic profile compared to existing or pipeline competitors.

Total Addressable Market (TAM)

The Total Addressable Market for Alzheimer's disease therapies is estimated to be in the tens of billions of dollars annually and is projected to grow significantly due to the increasing aging population. Acumen Pharmaceuticals Inc. is positioned to capture a portion of this market if ACU193 demonstrates efficacy and safety in late-stage clinical trials and receives regulatory approval.

Upturn SWOT Analysis

Strengths

  • Novel therapeutic candidate (ACU193) with a distinct mechanism of action targeting amyloid-beta oligomers.
  • Experienced management and scientific team with expertise in neurodegenerative diseases.
  • Focus on a significant unmet medical need in Alzheimer's disease.
  • Positive early-stage clinical data for ACU193.

Weaknesses

  • Clinical-stage company with no approved products, thus no revenue generation from sales.
  • High reliance on the success of a single lead candidate (ACU193).
  • Significant capital requirements for late-stage clinical development and potential commercialization.
  • Potential for manufacturing complexities for a monoclonal antibody.

Opportunities

  • Growing global demand for effective Alzheimer's disease treatments.
  • Potential for strategic partnerships or acquisition by larger pharmaceutical companies.
  • Advancements in diagnostic tools and biomarkers for earlier disease detection.
  • Expansion into other neurodegenerative diseases with similar underlying pathologies.

Threats

  • High failure rate in Alzheimer's disease drug development.
  • Intense competition from other pharmaceutical companies with advanced Alzheimer's candidates.
  • Regulatory hurdles and stringent approval processes.
  • Potential for unforeseen safety issues in later-stage clinical trials.
  • Reimbursement challenges for novel, high-cost therapies.

Competitors and Market Share

Key competitor logo Key Competitors

  • Biogen Inc. (BIIB)
  • Eli Lilly and Company (LLY)
  • Eisai Co., Ltd. (ESALY - ADR)

Competitive Landscape

Acumen Pharmaceuticals Inc. faces strong competition from established pharmaceutical giants with significant R&D budgets and existing market presence. Its advantage lies in its focused approach on a specific target within Alzheimer's pathology. However, it operates in a highly capital-intensive and risky sector where significant investment is required for even a chance at market success.

Growth Trajectory and Initiatives

Historical Growth: Acumen Pharmaceuticals Inc.'s growth trajectory has been characterized by its progression through preclinical and early clinical development stages. Growth is measured by advancements in its pipeline, successful fundraising rounds, and expansion of its scientific and operational capabilities.

Future Projections: Future projections are highly dependent on the success of ACU193 in Phase 2 and subsequent Phase 3 trials, as well as regulatory approvals. Analyst estimates, if available, would focus on potential peak sales and market penetration in the Alzheimer's disease market. The company's ability to secure further funding will also be a key factor.

Recent Initiatives: Recent initiatives likely include the initiation and progression of clinical trials for ACU193, potential collaborations with research institutions, and ongoing efforts to secure financing to support its development pipeline.

Summary

Acumen Pharmaceuticals Inc. is a promising clinical-stage biopharmaceutical company focused on Alzheimer's disease with a novel candidate, ACU193. Its strengths lie in its focused therapeutic approach and experienced team, while its weaknesses include being pre-revenue and the inherent risks of drug development. Key opportunities include the massive unmet need in Alzheimer's, but threats arise from intense competition and regulatory challenges. The company's future hinges on the successful progression of ACU193 through clinical trials.

Similar Stocks

Sources and Disclaimers

Data Sources:

  • Company SEC Filings (e.g., S-1, 10-K, 10-Q)
  • Industry Reports and Market Research
  • Financial News and Analysis Platforms
  • Company Website (for general information and press releases)

Disclaimers:

This JSON output is an overview based on publicly available information and general industry knowledge. Specific financial figures and detailed company history require access to proprietary databases and up-to-date regulatory filings. This analysis should not be considered investment advice. Investors should conduct their own due diligence and consult with financial professionals before making investment decisions. Placeholder values have been used where specific data was not readily available in a general overview context.

Information icon for Upturn AI Summarization accuracy disclaimer AI Summarization is directionally correct and might not be accurate.

Information icon for Upturn AI Summarization data freshness disclaimer Summarized information shown could be a few years old and not current.

Information icon warning about Upturn AI Fundamental Rating based on potentially old data Fundamental Rating based on AI could be based on old data.

Information icon warning about potential inaccuracies or hallucinations in Upturn AI-generated summaries AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Acumen Pharmaceuticals Inc

Exchange NASDAQ
Headquaters Newton, MA, United States
IPO Launch date 2021-07-01
CEO & Director Mr. Daniel J. O'Connell M.B.A.
Sector Healthcare
Industry Biotechnology
Full time employees 61
Full time employees 61

Acumen Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, develops targeted therapies for the treatment of Alzheimer's disease. The company focuses on advancing a targeted immunotherapy drug candidate Sabirnetug (ACU193), a recombinant humanized immunoglobulin gamma 2, which has completed the INTERCEPT-AD phase 1 clinical trial and in ALTITUDE-AD phase 2 clinical trial to target soluble amyloid-beta oligomers. It has a collaboration and license agreement with Halozyme, Inc. for the development of a subcutaneous formulation of Sabirnetug. Acumen Pharmaceuticals, Inc. was incorporated in 1996 and is headquartered in Newton, Massachusetts.