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AC Immune Ltd (ACIU)

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Upturn Advisory Summary
12/12/2025: ACIU (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $9.02
1 Year Target Price $9.02
| 3 | Strong Buy |
| 1 | Buy |
| 0 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -35.24% | Avg. Invested days 22 | Today’s Advisory PASS |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 316.89M USD | Price to earnings Ratio - | 1Y Target Price 9.02 |
Price to earnings Ratio - | 1Y Target Price 9.02 | ||
Volume (30-day avg) 4 | Beta 1.6 | 52 Weeks Range 1.43 - 4.00 | Updated Date 12/14/2025 |
52 Weeks Range 1.43 - 4.00 | Updated Date 12/14/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.9 |
Earnings Date
Report Date 2025-11-14 | When - | Estimate -0.1898 | Actual -0.16 |
Profitability
Profit Margin - | Operating Margin (TTM) -1671.89% |
Management Effectiveness
Return on Assets (TTM) -21.97% | Return on Equity (TTM) -74.63% |
Valuation
Trailing PE - | Forward PE 11.24 | Enterprise Value 186297253 | Price to Sales(TTM) 72.48 |
Enterprise Value 186297253 | Price to Sales(TTM) 72.48 | ||
Enterprise Value to Revenue 33.87 | Enterprise Value to EBITDA -0.76 | Shares Outstanding 100600000 | Shares Floating 40064895 |
Shares Outstanding 100600000 | Shares Floating 40064895 | ||
Percent Insiders 38.01 | Percent Institutions 24.85 |
About AC Immune Ltd
Exchange NASDAQ | Headquaters - | ||
IPO Launch date 2016-09-23 | Co-Founder, CEO & Director Dr. Andrea Pfeifer Ph.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 133 | Website https://www.acimmune.com |
Full time employees 133 | Website https://www.acimmune.com | ||
AC Immune SA, a clinical stage biopharmaceutical company, discovers, designs, and develops medicines, and therapeutic and diagnostic products for the prevention and treatment of neurodegenerative diseases associated with protein misfolding. The company's SupraAntigen and Morphomer platforms are designed to generate biologics and small molecules, which selectively interact with misfolded proteins that are common in a range of neurodegenerative diseases. It develops Crenezumab, a humanized, conformation specific monoclonal antibody used to slow Alzheimer's disease (AD) progression; and Semorinemab, an investigational monoclonal anti Tau antibody that targets the N-terminal portion of the Tau protein and is designed to bind to Tau and slow its spread between neurons for the treatment of AD. The company is also developing ACI-24.060 for the treatment of down syndrome related AD; ACI-7104.056 to treat Parkinson's disease; and ACI-35.030, designs to stimulate a patient's immune system to produce antibodies against pathological phosphorylated Tau. In addition, it develops diagnostic programs consisting of PI-2620, a Tau diagnostic for AD, as well as non-AD Tauopathies; and ACI-12589, a-sync PET tracer that supports the differential diagnosis of multiple system atrophy from other neurodegenerative disease. Further, the company is researching and developing Morphomer Tau aggregation inhibitors to evaluate candidates in AD; Morphomer a-syn to compete with small molecule inhibitors of a-syn aggregation; and NeuroOrphan Tauopathies. Additionally, it generates discovery and preclinical stage molecules targeting range of neurodegenerative diseases, which include diagnostics targeting TDP-43, alpha-synuclein, and NLRP3. The company has license agreements and collaborations with Genentech, Inc.; Janssen Pharmaceuticals, Inc.; Life Molecular Imaging SA; and Eli Lilly and Company. AC Immune SA was incorporated in 2003 and is headquartered in Lausanne, Switzerland.

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