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AC Immune Ltd(ACIU)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Stock price based on last close Advisory Performance History (Simulated)
Upturn Advisory & Investor View for ACIU
11/13/2026: ACIU (1-star) is currently NOT-A-BUY. Pass it for now.
AC Immune is a clinical-stage biotechnology company focused on developing precision medicines for neurodegenerative disorders, particularly Alzheimer's and Parkinson's. Its main strength lies in a robust research platform that targets misfolded proteins, supported by partnerships with large pharmaceutical companies. While the company offers a significant growth opportunity if its clinical trials yield breakthrough treatments, it faces high execution, regulatory, and competitive risks common to the biotech sector. The stock is best suited for growth-oriented investors who can tolerate high volatility and extended development timelines. Monitoring progress on clinical trial data and potential new partnership agreements is essential for assessing the company's future trajectory.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Mixed fit | The company offers high-growth potential driven by clinical innovation but carries significant binary risk. |
| Momentum investor | Weak fit | Momentum suitability is conditional on positive clinical data readouts or strong sector-wide trends. |
| Value investor | Weak fit | The lack of earnings and reliance on speculative R&D makes it unsuitable for traditional value strategies. |
| Dividend investor | Weak fit | AC Immune does not pay dividends and focuses all capital on development. |
| Low-risk investor | Weak fit | The high volatility and clinical risk profile are incompatible with low-risk investment mandates. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | Biotech stocks often experience extreme price swings around clinical data release dates. |
| Valuation risk | High | Valuations are highly speculative and depend on future drug approval probabilities. |
| Competition risk (large cap pharma) | High | The company faces competition from deep-pocketed firms that can outspend it on clinical trials. |
| Business quality | Medium | While the technology platform is respected, the company lacks a self-sustaining commercial product. |
| Dividend income | Low / none | No income is generated for investors through dividends. |
| Execution risk | High | Success depends on the company's ability to successfully navigate complex clinical trial processes. |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 211.78M USD | Price to earnings Ratio - | 1Y Target Price 8.38 |
Price to earnings Ratio - | 1Y Target Price 8.38 | ||
Volume (30-day avg) 202.8K shares | Beta 1.61 | 52 Weeks Range 2.02 - 3.90 | Updated Date 11/14/2026 |
52 Weeks Range 2.02 - 3.90 | Updated Date 11/14/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.44 |
Sector & Industry Intelligence
Sector
Healthcare
Bullish- Sentiment
- Strong Bullish
- Momentum
- Momentum Steady
- BUY participation
- 62.6%
- Active BUY / eligible
- 72 / 115
- 30-Day BUY Count Change
- +35
- Market state
- Strong Bullish
The number of qualifying BUY stocks has remained relatively stable.
Industry
Biotechnology
- BUY participation
- 45.5%
- Active BUY / eligible
- 20 / 44
- 30-Day BUY Count Change
- +13
Sector signal summarizes BUY breadth conditions for the sector. It does not override this stock’s BUY, SELL, or PASS advisory.
Price Behavior
Downtrend
The stock has experienced a sustained decline in price over recent periods.
Choppy
The stock has experienced frequent reversals and pronounced short-term price swings.
Analysis of Past Performance
Type Stock | Historic Profit -20.3% | Avg. Invested days 27 | Today’s Advisory PASS |
Upturn Advisory Rating  | Upturn Advisory Performance  2.0 | Stock Returns Performance  1.0 |
| Profits based on simulation | Last Close 11/13/2026 |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals
Financial Health Rating
Growth Momentum Score
Ownership
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue)
Economic Dimensions
Quantitative Style Profile
Style Classification
Quality Focused
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Research Collaborations | Milestone payments and royalties from partnerships with pharmaceutical majors. | Revenue is not from product sales but from payments earned by hitting research goals. |
Valuation
Trailing PE - | Forward PE 4.99 | Enterprise Value 128.66M | Price to Sales(TTM) 10.69 |
Enterprise Value 128.66M | Price to Sales(TTM) 10.69 | ||
Enterprise Value to Revenue 5.43 | Enterprise Value to EBITDA -0.76 | Shares Outstanding 99.43M | Shares Floating 26.52M |
Shares Outstanding 99.43M | Shares Floating 26.52M | ||
Percent Insiders 38.15 | Percent Institutions 24.23 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
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