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Upturn AI Summary - About
Aclaris Therapeutics Inc(ACRS)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Advisory Performance History (Simulated)
Upturn Advisory & Investor View for ACRS
11/06/2026: ACRS (4-star) is currently NOT-A-BUY. Pass it for now.
Aclaris Therapeutics is a clinical-stage biotechnology company focused on developing novel, small-molecule drug candidates for inflammatory and autoimmune diseases. The company is known for its lean, R&D-centric model and deep technical expertise in kinase inhibition. Its primary investment story hinges on successful clinical data readouts and potential licensing deals that could validate its pipeline. However, the company faces significant risks, including intense competition from large pharmaceutical players, binary clinical trial outcomes, and the ongoing need for capital. It may suit speculative investors comfortable with the high volatility typical of clinical-stage biotechnology stocks, while key developments to monitor include upcoming clinical trial results and future partnership announcements.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Mixed fit | Investors seeking high-risk, high-reward exposure to clinical-stage biotech may find the company's pipeline potential appealing despite the lack of current commercial success. |
| Momentum investor | Weak fit | Momentum investors should wait for clear clinical trial breakthroughs or major licensing signals before considering a position. |
| Value investor | Weak fit | The company lacks current earnings or tangible assets to support a traditional value-based investment thesis. |
| Dividend investor | Weak fit | Aclaris is a clinical-stage biotechnology company that does not pay dividends. |
| Low-risk investor | Weak fit | Clinical-stage biotechnology stocks are highly volatile and carry significant binary regulatory risks unsuitable for risk-averse portfolios. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | The stock is susceptible to extreme price swings based on clinical data updates and financing events. |
| Valuation risk | Medium / high | Valuations for non-revenue-generating biotech firms are often speculative and subject to rapid adjustments. |
| Competition risk (Major Pharma) | High | Aclaris competes directly against massive, established firms with greater R&D and commercial capabilities. |
| Business quality | Medium | The company's long-term viability depends heavily on the successful execution of its limited drug pipeline. |
| Dividend income | Low / none | The company does not provide any income to shareholders. |
| Execution risk | High | Failure at any stage of clinical trials or the inability to secure funding poses a material threat to the business. |
Price Behavior

Rolling Over
The price momentum is slowing down and beginning to turn downward.

Choppy
The stock has experienced frequent reversals and pronounced short-term price swings.
Analysis of Past Performance
Type Stock | Historic Profit 84.62% | Avg. Invested days 26 | Today’s Advisory PASS |
Upturn Advisory Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals 
Financial Health Rating 
Growth Momentum Score 
Ownership 
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue) 
Economic Dimensions
Quantitative Style Profile 
Style Classification
Quality Focused
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 559.49M USD | Price to earnings Ratio - | 1Y Target Price 10.36 |
Price to earnings Ratio - | 1Y Target Price 10.36 | ||
Volume (30-day avg) 3.6M shares | Beta 0.94 | 52 Weeks Range 2.10 - 6.60 | Updated Date 11/06/2026 |
52 Weeks Range 2.10 - 6.60 | Updated Date 11/06/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.59 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| License and Research Revenue | Milestone payments, upfront payments, and potential royalties from partnerships. | Revenue is sporadic and depends on the company's ability to successfully license its drug candidates. |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Valuation
Trailing PE - | Forward PE - | Enterprise Value 359.54M | Price to Sales(TTM) 68.07 |
Enterprise Value 359.54M | Price to Sales(TTM) 68.07 | ||
Enterprise Value to Revenue 58.16 | Enterprise Value to EBITDA 0.28 | Shares Outstanding 154.98M | Shares Floating 103.48M |
Shares Outstanding 154.98M | Shares Floating 103.48M | ||
Percent Insiders 2.18 | Percent Institutions 84.39 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

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