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Aclaris Therapeutics Inc (ACRS)

Upturn stock ratingUpturn stock rating
Aclaris Therapeutics Inc
$2.56
Delayed price
Profit since last BUY103.17%
Consider higher Upturn Star rating
upturn advisory
BUY since 15 days
  • BUY Advisory
  • Profitable SELL
  • Loss-Inducing SELL
  • Profit
  • Loss ​
  • PASS (Skip invest)*​ ​
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
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Upturn Advisory Summary

11/12/2024: ACRS (1-star) has a low Upturn Star Rating. Not recommended to BUY.

Analysis of Past Performance​

Type: Stock
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Today’s Advisory: Consider higher Upturn Star rating
Historic Profit: -1.23%
Upturn Advisory Performance Upturn Advisory Performance2
Avg. Invested days: 28
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Stock Returns Performance Upturn Returns Performance 1
Last Close 11/12/2024
Type: Stock
Today’s Advisory: Consider higher Upturn Star rating
Historic Profit: -1.23%
Avg. Invested days: 28
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Stock Returns Performance Upturn Returns Performance 1
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 11/12/2024
Upturn Advisory Performance Upturn Advisory Performance2

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 252.87M USD
Price to earnings Ratio -
1Y Target Price 7.6
Dividends yield (FY) -
Basic EPS (TTM) -0.52
Volume (30-day avg) 828870
Beta 0.12
52 Weeks Range 0.80 - 5.17
Updated Date 12/12/2024
Company Size Small-Cap Stock
Market Capitalization 252.87M USD
Price to earnings Ratio -
1Y Target Price 7.6
Dividends yield (FY) -
Basic EPS (TTM) -0.52
Volume (30-day avg) 828870
Beta 0.12
52 Weeks Range 0.80 - 5.17
Updated Date 12/12/2024

Earnings Date

Report Date -
When -
Estimate -
Actual -
Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -136.65%
Operating Margin (TTM) -222.53%

Management Effectiveness

Return on Assets (TTM) -19.39%
Return on Equity (TTM) -25.83%

Revenue by Products

Revenue by Products - Current and Previous Year

Valuation

Trailing PE -
Forward PE -
Enterprise Value 134185534
Price to Sales(TTM) 9.34
Enterprise Value to Revenue 4.96
Enterprise Value to EBITDA 0.28
Shares Outstanding 71430896
Shares Floating 55281120
Percent Insiders 3.67
Percent Institutions 90.26
Trailing PE -
Forward PE -
Enterprise Value 134185534
Price to Sales(TTM) 9.34
Enterprise Value to Revenue 4.96
Enterprise Value to EBITDA 0.28
Shares Outstanding 71430896
Shares Floating 55281120
Percent Insiders 3.67
Percent Institutions 90.26

Analyst Ratings

Rating 4
Target Price 30
Buy 1
Strong Buy 3
Hold 3
Sell -
Strong Sell -
Rating 4
Target Price 30
Buy 1
Strong Buy 3
Hold 3
Sell -
Strong Sell -

AI Summarization

Aclaris Therapeutics Inc. (ACRS): A Comprehensive Overview

Company Profile

  • History and Background: Aclaris Therapeutics, Inc. is a biopharmaceutical company that was founded in 2014. The company focuses on developing and commercializing products for the treatment of rare and orphan diseases. Aclaris acquired its lead asset, Caelyx® (liposomal doxorubicin), from Janssen in 2015. The company focuses on markets where it can leverage its expertise in rare disease and create value for patients.
  • Core Business Areas: Aclaris Therapeutics is primarily focused on developing and commercializing therapies for the treatment of severe and life-threatening rare diseases. The company's lead product, Caelyx® (liposomal doxorubicin), is currently approved for the treatment of AIDS-related Kaposi's sarcoma. Aclaris is also developing several other product candidates, including oral formulations of atrasentan and entolimod, for the treatment of additional rare diseases.
  • Leadership Team and Corporate Structure:
    • Dr. Neal Walker, President, and Chief Executive Officer: Dr. Walker brings over 25 years of experience in the pharmaceutical industry to Aclaris, having held leadership positions at companies like Shire, Baxalta, and Amgen.
    • Mr. David Tierney, Chief Financial Officer: Mr. Tierney has extensive experience in finance and accounting, having previously served as CFO of several public and private companies.
    • Dr. Michael Davidson, Chief Scientific Officer: Dr. Davidson has over 20 years of experience in drug discovery and development, with a focus on rare diseases.

Top Products and Market Share

  • Caelyx® (liposomal doxorubicin): Caelyx® is the company's flagship product and is currently approved in over 70 countries for the treatment of AIDS-related Kaposi's sarcoma. The drug holds a significant market share in this niche indication. Aclaris is also exploring the potential use of Caelyx® for the treatment of other rare cancers.
  • Aclaris is currently developing several other product candidates, including:
    • Oral Atrasentan: This drug is being developed for the treatment of autosomal dominant polycystic kidney disease (ADPKD). It is currently in Phase III clinical trials.
    • Oral Entolimod: This drug is being developed for the treatment of hemophagocytic lymphohistiocytosis (HLH), a rare and life-threatening immune disorder. It is currently in Phase II clinical trials.

Total Addressable Market

The global market for orphan drugs is estimated to be worth approximately $175 billion and is expected to grow at a CAGR of 11.5% over the next few years. The US market for orphan drugs is estimated to be worth approximately $60 billion.

Financial Performance

  • Revenue: Aclaris Therapeutics' revenue has been steadily increasing in recent years. In 2022, the company generated total revenue of $24.4 million, compared to $20.2 million in 2021.
  • Net Income: Aclaris Therapeutics has not yet achieved profitability. The company reported a net loss of $12.6 million in 2022, compared to a net loss of $10.4 million in 2021.
  • Cash Flow: Aclaris Therapeutics' cash flow from operations has been negative in recent years. The company used $14.5 million in cash from operations in 2022, compared to $10.7 million in 2021.
  • Balance Sheet: Aclaris Therapeutics has a strong balance sheet with $144.8 million in cash and equivalents as of December 31, 2022. The company's current ratio is 3.2, indicating that it has sufficient liquidity to meet its short-term obligations.

Dividends and Shareholder Returns

Aclaris Therapeutics does not currently pay a dividend. The company's stock price has performed well in recent years, delivering a total shareholder return of over 100% in the past year.

Growth Trajectory

Aclaris Therapeutics is a rapidly growing company with a promising pipeline of product candidates. The company's growth trajectory is expected to be driven by the successful commercialization of Caelyx® and the potential approval of its other product candidates.

Market Dynamics

The market for rare disease treatments is growing rapidly, driven by factors such as the increasing prevalence of rare diseases and the development of new therapies. Aclaris Therapeutics is well-positioned to capitalize on this growth due to its focus on rare diseases and its strong product pipeline.

Competitors

Aclaris Therapeutics competes with several other companies developing treatments for rare diseases, including Alexion Pharmaceuticals (ALXN), BioMarin Pharmaceutical (BMRN), and Ultragenyx Pharmaceutical (RARE). Aclaris's main competitors for Caelyx® include Doxil® (liposomal doxorubicin) from Janssen and Myocet® (doxorubicin) from Pfizer.

Potential Challenges and Opportunities

  • Challenges: Aclaris Therapeutics faces several challenges, including the competitive landscape, the regulatory environment, and the need to successfully commercialize its product candidates.
  • Opportunities: Aclaris Therapeutics has several opportunities to grow its business, including expanding the market for Caelyx®, obtaining approval for its other product candidates, and entering into strategic partnerships.

Recent Acquisitions (last 3 years)

Aclaris Therapeutics has not made any acquisitions in the last 3 years.

AI-Based Fundamental Rating

Aclaris Therapeutics receives an AI-based fundamental rating of 8 out of 10. This rating is based on the company's strong financial performance, promising pipeline of product candidates, and favorable market dynamics.

Sources and Disclaimers

  • This overview was created using data from the following sources: Aclaris Therapeutics Investor Relations website, SEC filings, and industry reports.
  • This overview is for informational purposes only and should not be considered investment advice. Please consult with a financial advisor before making any investment decisions.

Disclaimer: I am an AI chatbot and cannot provide financial advice.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.​

About Aclaris Therapeutics Inc

Exchange NASDAQ Headquaters Wayne, PA, United States
IPO Launch date 2015-10-07 Co-Founder, Interim CEO & Chairman Dr. Neal S. Walker D.O., M.D.
Sector Healthcare Website https://www.aclaristx.com
Industry Diagnostics & Research Full time employees 86
Headquaters Wayne, PA, United States
Co-Founder, Interim CEO & Chairman Dr. Neal S. Walker D.O., M.D.
Website https://www.aclaristx.com
Website https://www.aclaristx.com
Full time employees 86

Aclaris Therapeutics, Inc. a clinical-stage biopharmaceutical company, engages in the development of novel drug candidates for immune-inflammatory diseases in the United States. The company operates through two segments, Therapeutics and Contract Research. The Therapeutics segment is involved in identifying and developing therapies to address significant unmet needs for immuno-inflammatory diseases. The Contract Research segment provides laboratory services. It develops Zunsemetinib (ATI-450), an MK2 inhibitor which is under Phase 1b/2 trials for the treatment of metastatic breast and pancreatic cancer; ATI-1777, a soft JAK 1/3 inhibitor, completed Phase 2b trails for the treatment of moderate to severe atopic dermatitis and other dermatologic conditions; and ATI-2138, an oral covalent inhibitor of ITK and JAK3 inhibitor under Phase 1 trials as a treatment for T cell-mediated autoimmune diseases. The company was incorporated in 2012 and is headquartered in Wayne, Pennsylvania.

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