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Upturn AI Summary - About
Addex Therapeutics Ltd(ADXN)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Advisory Performance History (Simulated)
Upturn Advisory & Investor View for ADXN
09/25/2026: ADXN (1-star) is currently NOT-A-BUY. Pass it for now.
Addex Therapeutics is a clinical-stage biotechnology company specializing in oral small-molecule allosteric modulators for neurological conditions. Its primary strength lies in its proprietary discovery platform, which has attracted significant partnerships with established pharmaceutical companies. The investment story centers on the potential of its clinical pipeline to address high-need markets like epilepsy and Parkinson's. However, the company faces substantial risks, including the high failure rate of clinical trials, limited capital, and intense competition from much larger, better-funded players. This stock is suited primarily for speculative investors with a high risk tolerance who are looking for exposure to novel drug discovery.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Mixed fit | The company offers high-risk, high-reward exposure to early-stage biotechnology innovation. |
| Momentum investor | Weak fit | Momentum is highly conditional on clinical data readouts rather than consistent technical trends. |
| Value investor | Weak fit | As a pre-revenue clinical company, traditional valuation metrics are not applicable. |
| Dividend investor | Weak fit | The company is not profitable and does not pay dividends. |
| Low-risk investor | Weak fit | Biotechnology development carries inherent risks of capital loss due to clinical failure. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | Clinical trial results can cause massive swings in stock price in either direction. |
| Valuation risk | Medium / high | Valuation is speculative and based on future potential rather than current fundamentals. |
| Competition risk | High | Large pharmaceutical competitors have significantly more resources to dominate the CNS space. |
| Business quality | Medium | The company is a niche player with a specialized platform but lacks established revenue streams. |
| Dividend income | Low / none | There is no income component to this investment. |
| Execution risk | High | The complexity of CNS drug development makes the probability of reaching market quite low. |
Price Behavior

Steep Decline
The stock price has dropped sharply with strong downward pressure.

Highly Choppy
The stock has experienced frequent, large price swings that make its near-term movement less predictable.
Analysis of Past Performance
Type Stock | Historic Profit -62.51% | Avg. Invested days 18 | Today’s Advisory PASS |
Upturn Advisory Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals 
Financial Health Rating 
Growth Momentum Score 
Ownership 
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue) 
Economic Dimensions
Quantitative Style Profile 
Style Classification
Quality Focused
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 4.38M USD | Price to earnings Ratio - | 1Y Target Price 30 |
Price to earnings Ratio - | 1Y Target Price 30 | ||
Volume (30-day avg) 288.1K shares | Beta 1.96 | 52 Weeks Range 3.10 - 11.97 | Updated Date 09/25/2026 |
52 Weeks Range 3.10 - 11.97 | Updated Date 09/25/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -8.8 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Partnership Revenue | Upfront payments, research funding, and milestone payments from collaborative partners. | Revenue is irregular and depends on hitting specific R&D milestones with partners. |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Valuation
Trailing PE - | Forward PE - | Enterprise Value 3.39M | Price to Sales(TTM) 40 |
Enterprise Value 3.39M | Price to Sales(TTM) 40 | ||
Enterprise Value to Revenue 92.75 | Enterprise Value to EBITDA -0.76 | Shares Outstanding 1.27M | Shares Floating 808.87K |
Shares Outstanding 1.27M | Shares Floating 808.87K | ||
Percent Insiders - | Percent Institutions 0.01 |
Upturn AI Summary
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
About Addex Therapeutics Ltd
Exchange NASDAQ | Headquarters - | ||
IPO Launch date 2020-01-29 | Co-Founder, CEO & Director Mr. Timothy Mark Dyer | ||
Sector Healthcare | Industry Biotechnology | Full time employees 3 | |
Full time employees 3 | |||
Addex Therapeutics Ltd discovers, develops, and commercializes small-molecule pharmaceutical products for neurological disorders in Switzerland. The company focuses on the discovery of G-protein coupled receptors and enzymes. Its lead programs include Dipraglurant, which is in phase 1 clinical trial for the treatment of post-stroke/TBI recovery, as well as to treat Parkinson's disease levodopa-induced dyskinesia. The company also develops ADX71149, which is in phase 1 for undisclosed indication; and GABAB PAM for the treatment pain, anxiety, addiction, chronic cough, and overactive bladder. It has license and collaboration agreement with Janssen Pharmaceuticals Inc. for the develop mGlu2 PAM compounds for the treatment of human health; and license and research agreement with Indivior PLC discovery, development, and commercialization of novel GABAB PAM compounds for the treatment of addiction and other CNS diseases. The company was formerly known as Addex Pharmaceuticals Ltd. Addex Therapeutics Ltd was founded in 2002 and is based in Geneva, Switzerland.

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