Addex Therapeutics Ltd logo

Addex Therapeutics Ltd(ADXN)

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ADVISORIES YOU CAN VERIFY
QUALITY SIGNAL
1-STAR RATING
PASS
LAST CLOSE
$3.65
09/25/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
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Advisory Performance History (Simulated)Advisory Performance History info

Upturn Advisory & Investor View for ADXN

09/25/2026: ADXN (1-star) is currently NOT-A-BUY. Pass it for now.

Addex Therapeutics is a clinical-stage biotechnology company specializing in oral small-molecule allosteric modulators for neurological conditions. Its primary strength lies in its proprietary discovery platform, which has attracted significant partnerships with established pharmaceutical companies. The investment story centers on the potential of its clinical pipeline to address high-need markets like epilepsy and Parkinson's. However, the company faces substantial risks, including the high failure rate of clinical trials, limited capital, and intense competition from much larger, better-funded players. This stock is suited primarily for speculative investors with a high risk tolerance who are looking for exposure to novel drug discovery.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorMixed fitThe company offers high-risk, high-reward exposure to early-stage biotechnology innovation.
Momentum investorWeak fitMomentum is highly conditional on clinical data readouts rather than consistent technical trends.
Value investorWeak fitAs a pre-revenue clinical company, traditional valuation metrics are not applicable.
Dividend investorWeak fitThe company is not profitable and does not pay dividends.
Low-risk investorWeak fitBiotechnology development carries inherent risks of capital loss due to clinical failure.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighClinical trial results can cause massive swings in stock price in either direction.
Valuation riskMedium / highValuation is speculative and based on future potential rather than current fundamentals.
Competition riskHighLarge pharmaceutical competitors have significantly more resources to dominate the CNS space.
Business qualityMediumThe company is a niche player with a specialized platform but lacks established revenue streams.
Dividend incomeLow / noneThere is no income component to this investment.
Execution riskHighThe complexity of CNS drug development makes the probability of reaching market quite low.

Price Behavior

Steep Decline
PRICE PATH

Steep Decline

The stock price has dropped sharply with strong downward pressure.

Highly Choppy
PRICE STABILITY

Highly Choppy

The stock has experienced frequent, large price swings that make its near-term movement less predictable.

Analysis of Past Performance

Type Stock
Historic Profit -62.51%
Avg. Invested days 18
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 1.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 09/25/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
ADXN receives a 2-star rating, supported by available scored pillars. The rating is constrained by weak unit economics, soft company fundamentals, and soft quantitative characteristics.

Company Fundamentals

★★★★★
ADXN has soft overall fundamentals (2 stars), with soft financial health, soft growth momentum, and soft ownership. In FY2025 versus FY2024, growth and ownership metrics are mixed: negative earnings growth (-195.4%), soft cash generation (FCF margin -6925.9%), negative revenue growth (-92.6%).

Financial Health Rating

★★★★★
ADXN's financial health is supported by soft efficiency, including operating-expense and cost-of-revenue discipline (opex 9490.8% of revenue). Overall financial-health metrics support a 2-star score.

Growth Momentum Score

★★★★★
Free-cash-flow growth is ADXN's strongest growth driver at +61.4% FY2025 versus FY2024 (strong, 5 stars). By comparison, while revenue growth (-92.6%, negative) and earnings growth (-195.4%, negative) hold the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 0.0% and approximately 63.9% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership is only 0.00%, which materially reduces the ownership score.

Top 5 Institutional Investors

Morgan Stanley - Brokerage Accounts 0.03%
Rhumbline Advisers 0.01%
SBI Securities Co Ltd 0.00%
GAMMA Investing LLC 0.00%
UBS Group AG 0.00%

Unit Economics (Per $1K Revenue)

★★★★★
ADXN generates approximately $1,000 of gross profit, $-93,908 of operating income, and $-69,259 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Strong cash conversion and healthy margins support the rating, although capital efficiency remains below the highest tier.

Economic Dimensions

★★★★★
Effective Tax Rate: 0.00%

Quantitative Style Profile

★★★★★
ADXN has a liquid profile. Weak momentum is the primary drawback, while valuation that is moderately attractive rather than deeply discounted.

Style Classification

Quality Focused

High VolatilitySmall / Mid Cap RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 4.38M USD
Price to earnings Ratio -
1Y Target Price 30
Price to earnings Ratio -
1Y Target Price 30
Volume (30-day avg) 288.1K shares
Beta 1.96
52 Weeks Range 3.10 - 11.97
Updated Date 09/25/2026
52 Weeks Range 3.10 - 11.97
Updated Date 09/25/2026
Dividends yield (FY) -
Basic EPS (TTM) -8.8

How Company Makes Money

Business areaWhat it includesRetail investor read
Partnership RevenueUpfront payments, research funding, and milestone payments from collaborative partners.Revenue is irregular and depends on hitting specific R&D milestones with partners.

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

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Valuation

Trailing PE -
Forward PE -
Enterprise Value 3.39M
Price to Sales(TTM) 40
Enterprise Value 3.39M
Price to Sales(TTM) 40
Enterprise Value to Revenue 92.75
Enterprise Value to EBITDA -0.76
Shares Outstanding 1.27M
Shares Floating 808.87K
Shares Outstanding 1.27M
Shares Floating 808.87K
Percent Insiders -
Percent Institutions 0.01

Icon representing Upturn AI-generated SWOT analysis summary Upturn AI Summary

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Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

About Addex Therapeutics Ltd

Exchange NASDAQ
Headquarters -
IPO Launch date 2020-01-29
Co-Founder, CEO & Director Mr. Timothy Mark Dyer
Sector Healthcare
Industry Biotechnology
Full time employees 3
Full time employees 3

Addex Therapeutics Ltd discovers, develops, and commercializes small-molecule pharmaceutical products for neurological disorders in Switzerland. The company focuses on the discovery of G-protein coupled receptors and enzymes. Its lead programs include Dipraglurant, which is in phase 1 clinical trial for the treatment of post-stroke/TBI recovery, as well as to treat Parkinson's disease levodopa-induced dyskinesia. The company also develops ADX71149, which is in phase 1 for undisclosed indication; and GABAB PAM for the treatment pain, anxiety, addiction, chronic cough, and overactive bladder. It has license and collaboration agreement with Janssen Pharmaceuticals Inc. for the develop mGlu2 PAM compounds for the treatment of human health; and license and research agreement with Indivior PLC discovery, development, and commercialization of novel GABAB PAM compounds for the treatment of addiction and other CNS diseases. The company was formerly known as Addex Pharmaceuticals Ltd. Addex Therapeutics Ltd was founded in 2002 and is based in Geneva, Switzerland.