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Addex Therapeutics Ltd (ADXN)

Upturn stock ratingUpturn stock rating
$9.41
Last Close (24-hour delay)
Profit since last BUY-8.02%
upturn advisory
Consider higher Upturn Star rating
BUY since 16 days
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
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Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
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Upturn Advisory Summary

06/30/2025: ADXN (1-star) has a low Upturn Star Rating. Not recommended to BUY.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

1 Analysts rated it

Very few follow this stock; limited insights, higher-risk early investing.

1 Year Target Price $30

1 Year Target Price $30

Analysts Price Target For last 52 week
$30Target price
Low$6.51
Current$9.41
high$13.27

Analysis of Past Performance

Type Stock
Historic Profit -47.27%
Avg. Invested days 22
Today’s Advisory Consider higher Upturn Star rating
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 1.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 06/30/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 9.62M USD
Price to earnings Ratio -
1Y Target Price 30
Price to earnings Ratio -
1Y Target Price 30
Volume (30-day avg) 1
Beta 1.99
52 Weeks Range 6.51 - 13.27
Updated Date 06/30/2025
52 Weeks Range 6.51 - 13.27
Updated Date 06/30/2025
Dividends yield (FY) -
Basic EPS (TTM) -7.46

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Earnings Date

Report Date 2025-06-19
When -
Estimate -
Actual -1.9991

Profitability

Profit Margin 3521.74%
Operating Margin (TTM) -853.23%

Management Effectiveness

Return on Assets (TTM) -25.09%
Return on Equity (TTM) -163.15%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 6091981
Price to Sales(TTM) 39.09
Enterprise Value 6091981
Price to Sales(TTM) 39.09
Enterprise Value to Revenue 28.6
Enterprise Value to EBITDA -0.76
Shares Outstanding 1069140
Shares Floating 26107116
Shares Outstanding 1069140
Shares Floating 26107116
Percent Insiders -
Percent Institutions 1.23

Analyst Ratings

Rating 1
Target Price 30
Buy 1
Strong Buy -
Buy 1
Strong Buy -
Hold -
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Addex Therapeutics Ltd

stock logo

Company Overview

overview logo History and Background

Addex Therapeutics Ltd is a pharmaceutical company pioneering allosteric modulation-based drug discovery and development. Founded in 2002, Addex has focused on creating novel therapies for neurological disorders and other diseases by selectively modulating G protein-coupled receptors (GPCRs).

business area logo Core Business Areas

  • Allosteric Modulator Discovery: Addex specializes in discovering and developing allosteric modulators, small molecules that modulate the activity of GPCRs without directly binding to the active site.
  • Drug Development: The company develops drug candidates based on its allosteric modulator platform, advancing them through preclinical and clinical stages.
  • Partnerships and Licensing: Addex collaborates with other pharmaceutical companies and licenses its technology and drug candidates.

leadership logo Leadership and Structure

Addex Therapeutics Ltd is led by a management team with experience in pharmaceutical research and development. The company operates with a structure that focuses on drug discovery, preclinical and clinical development, and business development.

Top Products and Market Share

overview logo Key Offerings

  • Dipraglurant: Dipraglurant is a negative allosteric modulator (NAM) of mGluR5. It was previously under development for Parkinsonu2019s disease levodopa-induced dyskinesia (PD-LID) and other neurological disorders. Addex is exploring partnering opportunities for this asset. Competitors in the PD-LID space include companies developing therapies targeting dopamine regulation and non-dopaminergic pathways. Market share data specific to Dipraglurant is not publicly available due to its development stage.
  • ADX71441: ADX71441 is a positive allosteric modulator (PAM) of mGluR2. The company is exploring partnering opportunities for this asset. Competitors in the mGluR2 modulation space include companies developing therapies for schizophrenia and anxiety disorders. Market share data specific to ADX71441 is not publicly available due to its development stage.

Market Dynamics

industry overview logo Industry Overview

The pharmaceutical industry is characterized by intense competition, high regulatory hurdles, and significant investment in research and development. There is a growing emphasis on precision medicine and targeted therapies.

Positioning

Addex Therapeutics Ltd is positioned as an innovator in allosteric modulation, offering a unique approach to drug discovery. Its competitive advantage lies in its proprietary technology platform and expertise in GPCR modulation.

Total Addressable Market (TAM)

The TAM for neurological disorders and other diseases targeted by Addex's pipeline is substantial, potentially reaching hundreds of billions of dollars globally. Addex's positioning within this TAM depends on the success of its clinical trials and partnering efforts.

Upturn SWOT Analysis

Strengths

  • Proprietary allosteric modulator platform
  • Expertise in GPCR modulation
  • Experienced management team
  • Potential for first-in-class therapies

Weaknesses

  • Limited financial resources
  • Dependence on partnerships for funding
  • Clinical trial risk
  • Small market capitalization

Opportunities

  • Partnerships with larger pharmaceutical companies
  • Expansion of pipeline into new therapeutic areas
  • Positive clinical trial results
  • Increasing demand for targeted therapies

Threats

  • Competition from established pharmaceutical companies
  • Regulatory hurdles
  • Patent expirations
  • Failure of clinical trials

Competitors and Market Share

competitor logo Key Competitors

  • NVS

Competitive Landscape

Addex faces competition from larger pharmaceutical companies with greater resources and established market presence. Its competitive advantage lies in its innovative allosteric modulation technology. Addex's small market share reflects the difference in resources and approved drugs between Addex and larger competitors.

Growth Trajectory and Initiatives

Historical Growth: Historical growth trends would be based on past financial performance and pipeline progress.

Future Projections: Future projections would be based on analyst estimates and company guidance.

Recent Initiatives: Recent strategic initiatives include focusing on partnering opportunities for existing assets and exploring new therapeutic areas.

Summary

Addex Therapeutics Ltd is a small cap biotech company with a unique allosteric modulator platform and expertise in GPCR modulation. The company faces challenges due to limited resources and clinical trial risks. Its potential lies in securing partnerships, advancing its pipeline, and capitalizing on the growing demand for targeted therapies. Addex's long term sucess is dependent on the partnering of their assets.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company website
  • SEC filings
  • Analyst reports
  • Industry publications

Disclaimers:

This analysis is based on publicly available information and is not financial advice. Investment decisions should be made after consulting with a qualified financial advisor.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Addex Therapeutics Ltd

Exchange NASDAQ
Headquaters -
IPO Launch date 2020-01-29
Co-Founder, CEO & Director Mr. Timothy Mark Dyer
Sector Healthcare
Industry Biotechnology
Full time employees 2
Full time employees 2

Addex Therapeutics Ltd discovers, develops, and commercializes small-molecule pharmaceutical products for neurological disorders in Switzerland. The company focuses on the discovery of G-protein coupled receptors and enzymes. Its lead programs include Dipraglurant, which is in phase 1 clinical trial for the treatment of post-stroke/TBI recovery, as well as to treat Parkinson's disease levodopa-induced dyskinesia. The company also develops ADX71149, a novel orally active metabotropic glutamate receptor subtype 2 positive allosteric modulator (mGlu2 PAM); and GABAB PAM for the treatment pain, anxiety, addiction, cough, and overactive bladder. It has license and collaboration agreement with Janssen Pharmaceuticals Inc. for the develop mGlu2 PAM compounds for the treatment of human health; and license and research agreement with Indivior PLC discovery, development, and commercialization of novel GABAB PAM compounds for the treatment of addiction and other CNS diseases. The company was formerly known as Addex Pharmaceuticals Ltd. Addex Therapeutics Ltd was founded in 2002 and is based in Geneva, Switzerland.