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AN2 Therapeutics Inc(ANTX)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Stock price based on last close Advisory Performance History (Simulated)
Upturn Advisory & Investor View for ANTX
11/09/2026: ANTX (1-star) is currently NOT-A-BUY. Pass it for now.
AN2 Therapeutics is a clinical-stage biopharmaceutical firm specializing in boron-chemistry to address rare, serious infectious diseases. Its primary value rests on the success of its lead candidate, Epetraborole, which targets NTM lung disease. While the company possesses a specialized technical platform and focused R&D approach, it faces significant risks including the lack of revenue, high cash burn, and binary outcomes from ongoing clinical trials. This stock is suitable for growth-oriented investors with high risk tolerance who are looking for exposure to potential breakthroughs in infectious medicine. Investors should monitor clinical trial data readouts and the company’s capital management closely.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Mixed fit | The company offers high growth potential linked to clinical success but carries significant binary risk. |
| Momentum investor | Weak fit | Momentum is often contingent on positive clinical trial updates, which are episodic and infrequent. |
| Value investor | Weak fit | The company lacks earnings, revenue, or established assets to support a traditional value-based valuation. |
| Dividend investor | Weak fit | AN2 does not pay a dividend and is unlikely to do so in the near future. |
| Low-risk investor | Weak fit | The high volatility and clinical-stage nature of the company are unsuitable for low-risk portfolios. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | Clinical-stage biotech stocks often experience sharp price swings based on trial results and regulatory updates. |
| Valuation risk | High | Valuation is speculative as it depends entirely on future clinical and commercial outcomes. |
| Competition risk (Infectious disease focus) | Medium / high | Established players in respiratory health hold significant market positions. |
| Business quality | Medium | While the technology platform is specialized, the company is still proving its commercial viability. |
| Dividend income | Low / none | There is no income component to this investment. |
| Execution risk | High | Success relies heavily on meeting complex clinical endpoints and securing regulatory approval. |
Price Behavior
Rolling Over
The price momentum is slowing down and beginning to turn downward.
Extreme Price Shocks
The stock has experienced exceptionally large and disruptive price movements during the period.
Analysis of Past Performance
Type Stock | Historic Profit -58.7% | Avg. Invested days 18 | Today’s Advisory PASS |
Upturn Advisory Rating  | Upturn Advisory Performance  2.0 | Stock Returns Performance  1.0 |
| Profits based on simulation | Last Close 11/09/2026 |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals
Financial Health Rating
Growth Momentum Score
Ownership
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue)
Economic Dimensions
Quantitative Style Profile
Style Classification
Quality Focused
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 150.94M USD | Price to earnings Ratio - | 1Y Target Price 9 |
Price to earnings Ratio - | 1Y Target Price 9 | ||
Volume (30-day avg) 305.9K shares | Beta -0.94 | 52 Weeks Range 1.00 - 7.19 | Updated Date 11/08/2026 |
52 Weeks Range 1.00 - 7.19 | Updated Date 11/08/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -1.05 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Drug Development | Research and clinical trial advancement of novel anti-infectives. | The company currently spends money rather than making it, with value creation dependent on future drug approvals. |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 72.56M | Price to Sales(TTM) - |
Enterprise Value 72.56M | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA -2.11 | Shares Outstanding 37.74M | Shares Floating 22.28M |
Shares Outstanding 37.74M | Shares Floating 22.28M | ||
Percent Insiders 15.99 | Percent Institutions 77.77 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
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