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AN2 Therapeutics Inc (ANTX)

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Upturn Advisory Summary
12/05/2025: ANTX (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $1
1 Year Target Price $1
| 0 | Strong Buy |
| 1 | Buy |
| 1 | Hold |
| 0 | Sell |
| 1 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit 79.7% | Avg. Invested days 53 | Today’s Advisory PASS |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 30.14M USD | Price to earnings Ratio - | 1Y Target Price 1 |
Price to earnings Ratio - | 1Y Target Price 1 | ||
Volume (30-day avg) 3 | Beta -0.03 | 52 Weeks Range 1.01 - 1.59 | Updated Date 12/6/2025 |
52 Weeks Range 1.01 - 1.59 | Updated Date 12/6/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -1.13 |
Earnings Date
Report Date 2025-11-12 | When - | Estimate -0.315 | Actual -0.31 |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -28.35% | Return on Equity (TTM) -45.91% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value -32600835 | Price to Sales(TTM) - |
Enterprise Value -32600835 | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA -2.11 | Shares Outstanding 27402024 | Shares Floating 17770487 |
Shares Outstanding 27402024 | Shares Floating 17770487 | ||
Percent Insiders 25.39 | Percent Institutions 39.36 |
Upturn AI SWOT
AN2 Therapeutics Inc
Company Overview
History and Background
AN2 Therapeutics Inc. was founded in 2018 with a focus on developing novel therapies for unmet medical needs in oncology and infectious diseases. The company has achieved several milestones, including advancing its lead asset through clinical trials and establishing strategic partnerships.
Core Business Areas
- Oncology: Development of small molecule therapies targeting specific cancer pathways.
- Infectious Diseases: Research and development of novel treatments for challenging infectious diseases.
Leadership and Structure
AN2 Therapeutics Inc. is led by a team of experienced biopharmaceutical executives and scientists. The organizational structure is typical for a clinical-stage biotechnology company, with departments focused on research and development, clinical operations, regulatory affairs, and corporate functions.
Top Products and Market Share
Key Offerings
- AN2-3411: A novel small molecule inhibitor targeting a key oncogenic pathway. Currently in clinical development for certain types of solid tumors. Competitors include companies developing similar targeted therapies, such as Bristol Myers Squibb (BMS), Pfizer, and Novartis, with varying market shares depending on the specific indication.
- Pipeline Candidates: AN2 Therapeutics Inc. also has a pipeline of other early-stage drug candidates in both oncology and infectious diseases, though specific details and market share are not yet applicable as they are in preclinical or early clinical stages.
Market Dynamics
Industry Overview
The biopharmaceutical industry is characterized by intense research and development, high regulatory hurdles, and significant market potential for breakthrough therapies. The oncology and infectious disease markets are large and growing, driven by an aging population, increasing disease prevalence, and advancements in scientific understanding.
Positioning
AN2 Therapeutics Inc. is positioned as a clinical-stage biopharmaceutical company aiming to address significant unmet medical needs. Its competitive advantages lie in its novel therapeutic approach and experienced scientific team.
Total Addressable Market (TAM)
The TAM for oncology and infectious disease therapeutics is in the hundreds of billions of dollars globally. AN2 Therapeutics Inc. is positioned to capture a portion of this market by developing differentiated therapies for specific patient populations within these broad disease areas.
Upturn SWOT Analysis
Strengths
- Novel drug candidates with potential for significant therapeutic benefit.
- Experienced management and scientific team.
- Focus on significant unmet medical needs.
- Established preclinical and early clinical data.
Weaknesses
- Clinical-stage company with no approved products yet.
- Reliance on future funding and successful clinical outcomes.
- Limited historical financial performance data.
- Small company size and resources compared to larger biotechs.
Opportunities
- Advancement of lead asset through clinical trials to potential market approval.
- Expansion into new indications or patient populations.
- Strategic partnerships and collaborations for further development and commercialization.
- Growth in the oncology and infectious disease markets.
Threats
- Clinical trial failures or unexpected safety issues.
- Competition from established pharmaceutical companies and emerging biotechs.
- Regulatory hurdles and delays.
- Changes in healthcare policy and reimbursement.
Competitors and Market Share
Key Competitors
- Bristol Myers Squibb (BMY)
- Pfizer (PFE)
- Merck & Co., Inc. (MRK)
- Novartis AG (NVS)
Competitive Landscape
AN2 Therapeutics Inc. faces intense competition from large, established pharmaceutical companies with significant resources and extensive product portfolios. Its advantage lies in potentially developing novel, first-in-class therapies for specific, underserved patient populations, which can command premium pricing and market positioning if successful.
Growth Trajectory and Initiatives
Historical Growth: As a relatively young company, historical growth is primarily defined by its progression from inception to its current clinical-stage development.
Future Projections: Future growth projections are highly dependent on the successful clinical development and eventual commercialization of its drug candidates. Analyst estimates are generally tied to anticipated clinical trial outcomes and market potential for its lead programs.
Recent Initiatives: Recent initiatives likely include the advancement of its lead drug candidate through clinical trials, potential formation of strategic partnerships, and ongoing efforts to secure necessary funding for its development programs.
Summary
AN2 Therapeutics Inc. is a promising clinical-stage biopharmaceutical company focused on developing innovative treatments for oncology and infectious diseases. Its strengths lie in its novel therapeutic candidates and experienced team. However, as a clinical-stage entity, it faces significant risks related to clinical trial success, regulatory approvals, and ongoing funding. The company needs to successfully navigate these challenges and demonstrate clinical efficacy to realize its growth potential in highly competitive markets.
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Sources and Disclaimers
Data Sources:
- Company filings (SEC)
- Industry analyst reports
- Financial news outlets
Disclaimers:
This JSON output is for informational purposes only and does not constitute financial advice. Information provided is based on publicly available data and may not be exhaustive or entirely accurate. Investors should conduct their own due diligence before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About AN2 Therapeutics Inc
Exchange NASDAQ | Headquaters Menlo Park, CA, United States | ||
IPO Launch date 2022-03-25 | Co-Founder, CEO, President & Chairman of the Board Mr. Eric E. Easom | ||
Sector Healthcare | Industry Biotechnology | Full time employees 22 | Website https://www.an2therapeutics.com |
Full time employees 22 | Website https://www.an2therapeutics.com | ||
AN2 Therapeutics, Inc., a biopharmaceutical company, focuses on discovering and developing novel small molecule therapeutics. The company's initial candidate includes epetraborole, which is phase 3 clinical trial as a once-daily oral treatment for patients with non-tuberculous mycobacterial lung disease, as well as studying for the treatment of acute melioidosis. It also develops AN2-502998 (AN15368), an investigational, boron-based small molecule in development for the treatment of chronic Chagas disease that is in preclinical trials; and has various research programs targeting the development of novel compounds in oncology and infectious disease based on its boron chemistry platform. It has a license agreement with Anacor Pharmaceuticals, Inc. to use, develop, manufacture, commercialize compounds and products, including epetraborole for the treatment, diagnosis, or prevention of various human diseases; and Brii Biosciences Limited to research, develop, manufacture, and commercialize compounds and products comprising epetraborole in China, Hong Kong, Taiwan, and Macau for the diagnosis, treatment, and prevention of human diseases; and GSK plc for the development of new therapies for TB. The company was incorporated in 2017 and is headquartered in Menlo Park, California.

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