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Artivion Inc (AORT)

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Upturn Advisory Summary
10/31/2025: AORT (4-star) is a STRONG-BUY. BUY since 8 days. Simulated Profits (4.37%). Updated daily EoD!
1 Year Target Price $45.26
1 Year Target Price $45.26
| 4 | Strong Buy |
| 2 | Buy |
| 0 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit 80.33% | Avg. Invested days 47 | Today’s Advisory Regular Buy |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Mid-Cap Stock | Market Capitalization 2.14B USD | Price to earnings Ratio - | 1Y Target Price 45.26 |
Price to earnings Ratio - | 1Y Target Price 45.26 | ||
Volume (30-day avg) 6 | Beta 1.67 | 52 Weeks Range 21.97 - 46.19 | Updated Date 11/1/2025 |
52 Weeks Range 21.97 - 46.19 | Updated Date 11/1/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.43 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Revenue by Geography
Geography revenue - Year on Year
Earnings Date
Report Date 2025-10-30 | When - | Estimate 0.0257 | Actual - |
Profitability
Profit Margin -4.43% | Operating Margin (TTM) 9.72% |
Management Effectiveness
Return on Assets (TTM) 1.7% | Return on Equity (TTM) -5.02% |
Valuation
Trailing PE - | Forward PE 53.19 | Enterprise Value 2125449678 | Price to Sales(TTM) 5.29 |
Enterprise Value 2125449678 | Price to Sales(TTM) 5.29 | ||
Enterprise Value to Revenue 5.25 | Enterprise Value to EBITDA 53.42 | Shares Outstanding 47183658 | Shares Floating 41609852 |
Shares Outstanding 47183658 | Shares Floating 41609852 | ||
Percent Insiders 4.5 | Percent Institutions 90.25 |
Upturn AI SWOT
Artivion Inc

Company Overview
History and Background
Artivion, Inc., formerly CryoLife, Inc., was founded in 1984. Initially focused on cryopreserved tissues, it has evolved into a leading provider of innovative cardiac and vascular surgery solutions. Significant milestones include expansion into mechanical heart valves, vascular grafts, and surgical sealants, broadening its portfolio through strategic acquisitions and internal development.
Core Business Areas
- Aortic Disease: This segment focuses on products used in the surgical repair and replacement of the aorta, including aortic valves, aortic arch grafts, and stent grafts.
- Cardiac Reconstruction: This includes products like surgical adhesives and sealants that help in repairing and reconstructing cardiac tissue during surgery.
- Vascular Repair: Offering grafts and patches used to repair or replace damaged or diseased blood vessels.
Leadership and Structure
Pat Mackin is the Chairman, President, and CEO. The company has a typical corporate structure with executive leadership overseeing various departments, including R&D, marketing, sales, operations, and finance.
Top Products and Market Share
Key Offerings
- On-X Aortic Heart Valve: A mechanical heart valve designed to reduce the need for anticoagulation therapy. Competitors include Medtronic, Edwards Lifesciences, and Abbott. Estimated Revenue: ~$80 million (estimated, based on segment reports).
- E-vita Open Plus Hybrid Stent Graft System: Used for treating complex aortic arch aneurysms and dissections. Competitors include Medtronic, Terumo Aortic, and Cook Medical. Estimated Revenue: ~$50 million (estimated, based on segment reports).
- BioGlue Surgical Adhesive: A protein-based surgical adhesive used for tissue sealing. Competitors include Baxter International and Ethicon (Johnson & Johnson). Estimated Revenue: ~$40 million (estimated, based on segment reports).
Market Dynamics
Industry Overview
The cardiac and vascular surgery market is driven by an aging population, increasing prevalence of cardiovascular diseases, and technological advancements in surgical techniques and devices. The market is highly competitive and regulated.
Positioning
Artivion Inc. is positioned as a specialty medical device company with a focus on innovative solutions for aortic and cardiac surgery. Its competitive advantages include its proprietary technologies, established relationships with surgeons, and a diversified product portfolio.
Total Addressable Market (TAM)
The global cardiovascular devices market is estimated to be over $50 billion. Artivion Inc. targets specific segments within this market. Based on their revenue and the broader market size of cardiovascular devices, Artivion's total addressable market is likely several billion dollars. It is well positioned due to its niche products.
Upturn SWOT Analysis
Strengths
- Specialized product portfolio
- Established relationships with surgeons
- Strong R&D capabilities
- Global sales and distribution network
Weaknesses
- Reliance on key products
- Small market capitalization compared to larger competitors
- Exposure to product liability risks
- Dependence on third-party manufacturers for some products
Opportunities
- Expanding into new geographies
- Developing new products through internal R&D and acquisitions
- Gaining market share from competitors
- Leveraging digital technologies for patient monitoring and data analysis
Threats
- Intense competition from larger medical device companies
- Pricing pressures from hospitals and payers
- Product recalls or safety concerns
- Changes in regulatory requirements
Competitors and Market Share
Key Competitors
- MDT
- EW
- ABT
Competitive Landscape
Artivion Inc. operates in a competitive market with several large medical device companies. It differentiates itself through its focus on specialized products and innovative technologies. However, it faces challenges from larger competitors with greater resources and broader product portfolios.
Major Acquisitions
Jotec AG
- Year: 2017
- Acquisition Price (USD millions): 225
- Strategic Rationale: Expanded Artivion's product portfolio in aortic arch and thoracic endovascular repair.
Ascyrus Medical
- Year: 2021
- Acquisition Price (USD millions): 190
- Strategic Rationale: Enhanced Artivion's aortic repair solutions with the Ascyrus Medical Dissection Stent (AMDS).
Growth Trajectory and Initiatives
Historical Growth: Artivion has demonstrated revenue growth over the past several years, driven by organic growth and strategic acquisitions. However, net income has been variable.
Future Projections: Analysts project continued revenue growth for Artivion, driven by its innovative product portfolio and expanding market presence. Profitability is expected to improve as the company scales and integrates its acquisitions.
Recent Initiatives: Recent initiatives include new product launches, geographic expansion, and strategic acquisitions to broaden its product offerings and market reach.
Summary
Artivion is a specialized medical device company that operates in the competitive cardiac and vascular surgery market. The company has shown revenue growth in recent years through strategic acquisitions and product development. However, profitability remains a challenge. While innovative products and surgeon relationships are strengths, the company must navigate competition, regulatory changes, and potential product liability risks.
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Sources and Disclaimers
Data Sources:
- Artivion Inc. Investor Relations
- SEC Filings (10-K, 10-Q)
- Industry Reports
- Analyst Estimates
- Company Press Releases
Disclaimers:
The information provided is for informational purposes only and does not constitute financial advice. Investment decisions should be based on thorough research and consultation with a qualified financial advisor. Market share figures are estimates and may vary based on different sources.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Artivion Inc
Exchange NYSE | Headquaters Kennesaw, GA, United States | ||
IPO Launch date 1993-02-12 | Chairman, President & CEO Mr. James Patrick Mackin | ||
Sector Healthcare | Industry Medical Devices | Full time employees 1600 | Website https://artivion.com |
Full time employees 1600 | Website https://artivion.com | ||
Artivion, Inc. manufactures, processes, and distributes medical devices and implantable human tissues worldwide. The company provides BioGlue, a polymer consisting of bovine blood protein and an agent for cross-linking proteins for cardiac, vascular, neurologic, and pulmonary procedures; cardiac and preservation services; PhotoFix, a bovine pericardial patch; and aortic arch stent grafts, including E-vita Open NEO, E-vita Open Plus, ascyrus medical dissection stent hybrid prosthesis, E-vita THORACIC 3G products, and NEXUS products. It also offers E-xtra design engineering systems for the treatment of aortic vascular diseases; E-nside, an off-the-shelf stent graft for the treatment of thoraco-abdominal disease; E-ventus BX, a balloon-expandable peripheral stent graft for the endovascular treatment of renal and pelvic arteries; E-liac to treat aneurysmal iliac arteries and aneurysmal iliac side branches; Tuva BX, a balloon-expandable peripheral stent graft to treat arterial ruptures, aneurysms, and other peripheral vascular system pathologies; and E-tegra, a stent graft system for the treatment of infrarenal abdominal aortic aneurysms. In addition, the company offers synthetic vascular grafts for use in open aortic and peripheral vascular surgical procedures; PerClot, an absorbable powdered hemostat for use in surgical procedures; CryoVein femoral vein and CryoArtery femoral artery vascular preservation services; On-X prosthetic aortic and mitral heart valves, and the On-X ascending aortic prosthesis; CarbonAid CO2 diffusion catheters; Chord-X ePTFE sutures for mitral chordal replacement; and pyrolytic carbon coating services to medical device manufacturers. It serves physicians, hospitals, and other healthcare facilities, as well as cardiac, vascular, thoracic, and general surgeons. The company was formerly known as CryoLife, Inc. and changed its name to Artivion, Inc. in January 2022. Artivion, Inc. was incorporated in 1984 and is headquartered in Kennesaw, Georgia.

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