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Applied DNA Sciences Inc (APDN)



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Upturn Advisory Summary
09/12/2025: APDN (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $1.5
1 Year Target Price $1.5
0 | Strong Buy |
0 | Buy |
1 | Hold |
0 | Sell |
0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -83.21% | Avg. Invested days 33 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 3.46M USD | Price to earnings Ratio - | 1Y Target Price 1.5 |
Price to earnings Ratio - | 1Y Target Price 1.5 | ||
Volume (30-day avg) 1 | Beta 0.07 | 52 Weeks Range 2.13 - 1091.25 | Updated Date 09/14/2025 |
52 Weeks Range 2.13 - 1091.25 | Updated Date 09/14/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -57.12 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Revenue by Geography
Geography revenue - Year on Year
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -1213.58% |
Management Effectiveness
Return on Assets (TTM) -64.06% | Return on Equity (TTM) -137.05% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value -932148 | Price to Sales(TTM) 0.92 |
Enterprise Value -932148 | Price to Sales(TTM) 0.92 | ||
Enterprise Value to Revenue 0.88 | Enterprise Value to EBITDA -0.34 | Shares Outstanding 1291460 | Shares Floating 1291439 |
Shares Outstanding 1291460 | Shares Floating 1291439 | ||
Percent Insiders 1.11 | Percent Institutions 6.92 |
Upturn AI SWOT
Applied DNA Sciences Inc

Company Overview
History and Background
Applied DNA Sciences Inc. (APDN) was founded in 1983. Initially focused on plant genetics, it evolved to specialize in DNA-based security and supply chain authentication solutions. It has undergone several strategic shifts to adapt to market demands and technological advancements, including its recent focus on biotherapeutic products and DNA manufacturing services.
Core Business Areas
- DNA Manufacturing Services: APDN provides DNA manufacturing services, producing linear DNA for various applications including mRNA vaccines, diagnostics, and therapeutics. This includes plasmid DNA production.
- Supply Chain Security Solutions: APDN offers DNA-based security solutions for supply chain authentication, anti-counterfeiting, and brand protection. This involves marking products with unique DNA signatures.
- Molecular Tagging: APDN provides a form of identifying, categorizing, and differentiating a wide variety of natural and synthetic products, and product lines, with tags that can be as small as a single molecule.
Leadership and Structure
Dr. James Hayward is the President and CEO. The company has a board of directors overseeing its operations and strategic direction. The organizational structure comprises functional departments focused on sales, marketing, research and development, manufacturing, and finance.
Top Products and Market Share
Key Offerings
- Linear DNA Manufacturing Services: Provides high-quality linear DNA for various therapeutic applications. Competitors in this market include Aldevron, GenScript, and Lonza. Specific market share data is difficult to ascertain but they are an emerging player.
- SigNature DNA: A DNA-based security solution used for anti-counterfeiting and supply chain authentication. Competitors include Authentix, De La Rue, and SICPA. Specific market share data is not publicly available. This segment's revenue contributes a substantial portion of their overall revenue.
Market Dynamics
Industry Overview
The DNA manufacturing services industry is experiencing rapid growth driven by advancements in gene therapy, mRNA vaccines, and personalized medicine. The supply chain security market is also growing due to increasing concerns about counterfeiting and product diversion.
Positioning
APDN is positioning itself as a key player in the DNA manufacturing space, leveraging its expertise in DNA technology. Its competitive advantages include its proprietary DNA manufacturing platform and established relationships with pharmaceutical and biotechnology companies.
Total Addressable Market (TAM)
The total addressable market for DNA manufacturing and supply chain security solutions is estimated to be in the billions of dollars. APDN is focused on capturing a significant share of this market through strategic partnerships and product innovation.
Upturn SWOT Analysis
Strengths
- Proprietary DNA manufacturing platform
- Expertise in DNA-based security solutions
- Strong intellectual property portfolio
- Established relationships with pharmaceutical and biotechnology companies
- High Barriers of entry
Weaknesses
- Limited financial resources
- Relatively small scale of operations
- Dependence on a few key customers
- History of net losses
Opportunities
- Growing demand for DNA manufacturing services
- Expanding applications of DNA-based security solutions
- Strategic partnerships with larger companies
- Government funding and grants
- Potential to lead with innovation
Threats
- Competition from larger, more established players
- Technological obsolescence
- Regulatory changes
- Economic downturns
- Supply Chain issues
Competitors and Market Share
Key Competitors
- TMO
- LTC
- CDXS
- Lonza
- Genscript
Competitive Landscape
APDN faces significant competition from larger, more established players with greater financial resources and market reach. However, APDN's proprietary technology and expertise in DNA-based solutions provide a competitive advantage in niche markets.
Major Acquisitions
Vitatex
- Year: 2011
- Acquisition Price (USD millions): 3.4
- Strategic Rationale: Accelerate its textile DNA-marking capabilities and expand its presence in the textile security market.
Growth Trajectory and Initiatives
Historical Growth: Historical growth has been uneven, characterized by periods of rapid expansion followed by periods of contraction.
Future Projections: Analyst estimates suggest potential for future growth driven by the increasing demand for DNA manufacturing services and supply chain security solutions.
Recent Initiatives: Recent strategic initiatives include expanding DNA manufacturing capacity, securing new partnerships with pharmaceutical companies, and developing innovative DNA-based security solutions.
Summary
Applied DNA Sciences is a smaller company with a unique DNA technology platform. While they have innovative offerings in DNA manufacturing and supply chain security, they face strong competition and have a history of net losses. Recent strategic initiatives aim to capitalize on growth opportunities, but financial stability remains a key challenge. The company's future success depends on its ability to secure partnerships, manage costs, and effectively compete in its chosen markets.
Peer Comparison
Sources and Disclaimers
Data Sources:
- Company SEC Filings
- Industry Reports
- Analyst Estimates
- Company Website
- Third Party Industry Data Providers
Disclaimers:
The data provided is for informational purposes only and should not be considered financial advice. Market share data may be estimates and subject to change. Investment decisions should be based on individual risk tolerance and thorough due diligence.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Applied DNA Sciences Inc
Exchange NASDAQ | Headquaters Stony Brook, NY, United States | ||
IPO Launch date 2003-07-15 | President, CEO, Chairperson & Secretary Ms. Judith Murrah | ||
Sector Healthcare | Industry Diagnostics & Research | Full time employees 46 | Website https://www.adnas.com |
Full time employees 46 | Website https://www.adnas.com |
Applied DNA Sciences, Inc., a biotechnology company, develops and commercializes technologies to produce and detect deoxyribonucleic acid (DNA) in the Americas, Europe, Asia, and internationally. It operates through three segments: Therapeutic DNA Production Services; MDx Testing Services; and DNA Tagging and Security Products and Services. The Therapeutic DNA Production Services segment develops and commercializes the LinearDNA platform, which enables a cell-free manufacture of high-fidelity synthetic DNA sequences for use in nucleic acid-based therapeutics. The MDx Testing Services segment provides clinical molecular diagnostics (MDx) testing and clinical laboratory testing services; COVID-19 testing services, including test scheduling, sample collection, and automated results reporting for higher education institutions, private clients, and businesses under the safeCircle trademark; polymerase chain reaction (PCR) for production and detection of DNA and RNA; and MDx test kits and related supplies, as well as Isotopic analysis testing services. The DNA Tagging and Security Products and Services segment offers SigNature Molecular Tags, which provides a methodology to authenticate goods within large and complex supply chains for materials, such as cotton, nutraceuticals, and other products; SigNify portable DNA readers and SigNify consumable reagent test kits; and fiberTyping, which uses PCR-based DNA detection to detect a product's naturally occurring DNA sequences for the purposes of product provenance authentication and supply chain security. The company was formerly known as Datalink Systems, Inc. and changed its name to Applied DNA Sciences, Inc. in 2002. The company was founded in 1983 and is headquartered in Stony Brook, New York.

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