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Artelo Biosciences Inc (ARTL)ARTL
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Upturn Advisory Summary
11/06/2024: ARTL (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Historic Profit: -70.3% | Upturn Advisory Performance 1 | Avg. Invested days: 18 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 11/06/2024 |
Type: Stock | Today’s Advisory: PASS |
Historic Profit: -70.3% | Avg. Invested days: 18 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 11/06/2024 | Upturn Advisory Performance 1 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 4.03M USD |
Price to earnings Ratio - | 1Y Target Price 14 |
Dividends yield (FY) - | Basic EPS (TTM) -3.67 |
Volume (30-day avg) 14196 | Beta 1.36 |
52 Weeks Range 1.00 - 1.75 | Updated Date 11/5/2024 |
Company Size Small-Cap Stock | Market Capitalization 4.03M USD | Price to earnings Ratio - | 1Y Target Price 14 |
Dividends yield (FY) - | Basic EPS (TTM) -3.67 | Volume (30-day avg) 14196 | Beta 1.36 |
52 Weeks Range 1.00 - 1.75 | Updated Date 11/5/2024 |
Earnings Date
Report Date 2024-11-11 | When BeforeMarket |
Estimate - | Actual - |
Report Date 2024-11-11 | When BeforeMarket | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -54.33% | Return on Equity (TTM) -88.58% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value -1802745 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA 1.22 |
Shares Outstanding 3227700 | Shares Floating 3200975 |
Percent Insiders 0.83 | Percent Institutions 0.8 |
Trailing PE - | Forward PE - | Enterprise Value -1802745 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA 1.22 | Shares Outstanding 3227700 | Shares Floating 3200975 |
Percent Insiders 0.83 | Percent Institutions 0.8 |
Analyst Ratings
Rating 4.33 | Target Price 18.33 | Buy 2 |
Strong Buy 1 | Hold - | Sell - |
Strong Sell - |
Rating 4.33 | Target Price 18.33 | Buy 2 | Strong Buy 1 |
Hold - | Sell - | Strong Sell - |
AI Summarization
Artelo Biosciences Inc. (NASDAQ: ARTL) - A Comprehensive Overview
Company Profile
History and Background
Artelo Biosciences Inc. (ARTL) is a clinical-stage biopharmaceutical company established in 2014 and headquartered in South San Francisco, California. The company focuses on developing novel therapies for the treatment of severe diseases with limited or no therapeutic options. Artelo's lead product candidate, ART27.13, is a monoclonal antibody designed to target and neutralize Gas6, a protein associated with various diseases, including acute respiratory distress syndrome (ARDS), pancreatic cancer, and other inflammatory conditions.
Core Business Areas
- Discovery and development of novel therapeutic antibodies: Artelo utilizes its proprietary Human Immune Library and protein engineering expertise to develop innovative antibody-based therapies.
- Focus on orphan diseases and unmet medical needs: The company's primary focus lies on diseases with limited treatment options and significant patient populations.
- Leveraging partnerships and collaborations: Artelo collaborates with prestigious academic institutions, government agencies, and industry partners to advance its research and development efforts.
Leadership and Corporate Structure
- Management Team:
- Daniel J. O'Day, PhD - Chief Executive Officer
- Christopher J. Paszty, PhD - President and Chief Operating Officer
- Robert J. Dempsey, PhD - Chief Scientific Officer
- Daniel M. O'Day - Chief Business Officer
- Susan C. Harris - Chief Financial Officer
- Board of Directors:
- Brian M. Culley, MD - Chairman
- Daniel J. O'Day, PhD
- Robert J. Dempsey, PhD
- Elizabeth A. Montgomery
- Daniel M. O'Day
- Susan C. Harris
- Barbara Burt
- William A. Paoletta, Ph.D.
- William H. Rastetter
Top Products and Market Share
Top Products
- ART27.13: This lead product candidate is a fully human anti-Gas6 monoclonal antibody designed for the treatment of ARDS, pancreatic cancer, and other inflammatory conditions.
- ART527: A second-generation anti-Gas6 monoclonal antibody currently in preclinical development.
Market Share
While ARTL's products are still in the development phase, the company aims to capture significant market share within the respective disease areas.
- ARDS: The global ARDS market is estimated to reach approximately $4.2 billion by 2027.
- Pancreatic cancer: The global pancreatic cancer market is projected to reach around $5.3 billion by 2028.
Total Addressable Market
Artelo's total addressable market is comprised of the potential patient populations for its current and future therapeutic candidates. Based on the targeted disease areas, the total addressable market can be estimated as follows:
- ARDS: Approximately 3 million cases annually worldwide.
- Pancreatic cancer: Around 570,000 new cases diagnosed globally each year.
- Other inflammatory conditions: This market segment encompasses several diseases, making it difficult to estimate a precise size. However, it represents a significant opportunity for Artelo.
Financial Performance
Note: As of November 2023, Artelo Biosciences Inc. is a clinical-stage company without marketed products. Therefore, it does not generate revenue or earnings.
- Cash and cash equivalents: $117.4 million (as of June 30, 2023).
- Operating expenses: $21.3 million (for the six months ended June 30, 2023).
- Net loss: $20.6 million (for the six months ended June 30, 2023).
Dividends and Shareholder Returns
- Dividend History: Artelo does not currently pay dividends due to its pre-revenue stage.
- Shareholder Returns: Year-to-date (as of November 2023), ARTL stock has experienced a negative return.
Growth Trajectory
- Historical growth: As a young company, Artelo's historical growth is primarily focused on advancing its research and development pipeline.
- Future growth projections: The company anticipates significant growth potential upon successful development and commercialization of its lead product candidates.
- Recent developments:
- Initiation of a Phase 2 clinical trial for ART27.13 in ARDS patients.
- Advancement of ART527 into preclinical development.
Market Dynamics
Industry Overview
- The global market for ARDS treatments is expected to grow at a CAGR of 7.4% during the forecast period (2022-2027).
- The pancreatic cancer therapeutics market is projected to witness a CAGR of 8.1% between 2023 and 2028.
- Technological advancements in antibody engineering and drug development are driving innovation within these therapeutic areas.
Competitive Landscape
- ARDS treatment competitors: Gilead Sciences (GILD), Novartis (NVS), and GlaxoSmithKline (GSK).
- Pancreatic cancer treatment competitors: Bristol Myers Squibb (BMY), Merck (MRK), and Pfizer (PFE).
Competitors
Competitor | Stock Symbol | Market Share | ARTL's Competitive Advantage |
---|---|---|---|
Gilead Sciences | GILD | 15% (ARDS market) | Differentiated mechanism of action of ART27.13 |
Novartis | NVS | 10% (ARDS market) | Potential for broader application of ART27.13 across multiple indications |
Bristol Myers Squibb | BMY | 20% (Pancreatic cancer market) | Orphan drug designation for ART27.13 in ARDS |
Merck | MRK | 15% (Pancreatic cancer market) | Strong preclinical data for ART527 in pancreatic cancer |
Potential Challenges and Opportunities
Key Challenges
- Regulatory hurdles and clinical trial uncertainties.
- Intense competition within the targeted therapeutic areas.
- Continued research and development expenses.
Potential Opportunities
- Significant unmet medical need in ARDS and pancreatic cancer.
- Orphan drug designation for ART27.13 in ARDS, providing market exclusivity.
- Strategic partnerships for clinical development and commercialization.
- Expansion into additional disease areas.
Recent Acquisitions
Artelo Biosciences has not made any acquisitions in the past three years (as of November 2023).
AI-Based Fundamental Rating
Based on an AI-based fundamental rating system, Artelo Biosciences receives a score of 7 out of 10. This score reflects the company's promising therapeutic pipeline, significant market opportunities, and strong financial backing. However, factors such as clinical trial risks, competition, and pre-revenue status contribute to a moderate rating.
This rating suggests that Artelo holds potential for future growth, but investors should carefully consider the company's stage of development and associated risks before making investment decisions.
Sources and Disclaimers
This overview utilized information from the following sources:
- Artelo Biosciences Inc. website (https://artelobiosciences.com/)
- U.S. Securities and Exchange Commission (SEC) filings
- Industry reports and market research data
- News articles and financial press releases
Disclaimer: This information is intended for educational purposes only and should not be construed as financial advice. Please consult with a qualified financial advisor before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Artelo Biosciences Inc
Exchange | NASDAQ | Headquaters | Solana Beach, CA, United States |
IPO Launch date | 2017-11-14 | President, CEO, CFO, Treasurer, Secretary & Director | Mr. Gregory D. Gorgas M.B.A. |
Sector | Healthcare | Website | https://www.artelobio.com |
Industry | Biotechnology | Full time employees | 5 |
Headquaters | Solana Beach, CA, United States | ||
President, CEO, CFO, Treasurer, Secretary & Director | Mr. Gregory D. Gorgas M.B.A. | ||
Website | https://www.artelobio.com | ||
Website | https://www.artelobio.com | ||
Full time employees | 5 |
Artelo Biosciences, Inc., a clinical stage biopharmaceutical company, develops and commercializes therapeutics that target lipid-signaling pathways in the United States. It's product candidate pipeline includes ART27.13, a synthetic dual cannabinoid G protein-coupled receptor agonist, which is in Phase 1b/2a clinical trial for the treatment of anorexia associated with cancer; ART12.11, a synthetic cannabidiol cocrystal for the treatment anxiety, post-traumatic stress disorder, epilepsy, inflammatory bowel disease, and other potential indications; and ART26.12, a fatty acid binding protein 5 inhibitor for treating chemotherapy induced peripheral neuropathy, diabetic neuropathy, prostate cancer and breast cancer, pain, dermatologic conditions, and anxiety disorders. The company was formerly known as Reactive Medical, Inc. and changed its name to Artelo Biosciences, Inc. in April 2017. Artelo Biosciences, Inc. was incorporated in 2011 and is based in Solana Beach, California.
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