Artiva Biotherapeutics, Inc. Common Stock logo

Artiva Biotherapeutics, Inc. Common Stock(ARTV)

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ADVISORIES YOU CAN VERIFY
QUALITY SIGNAL
1-STAR RATING
PASS
LAST CLOSE
$7.49
09/24/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
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Upturn Advisory & Investor View for ARTV

09/24/2026: ARTV (1-star) is currently NOT-A-BUY. Pass it for now.

Artiva Biotherapeutics is a clinical-stage biotechnology company developing off-the-shelf NK cell therapies to treat cancer and autoimmune diseases. Its primary strength lies in a proprietary, scalable manufacturing platform aimed at increasing patient access to cell-based treatments. The main growth story hinges on the clinical success of its lead candidate, AB-101. However, the company faces significant risks, including early-stage pipeline uncertainty, high capital requirements, and intense competition from major pharmaceutical firms. The stock is best suited for growth-oriented investors who can tolerate high volatility and recognize that long-term value depends entirely on successful clinical milestones and potential future commercialization.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorStrong fitThe company offers high-risk, high-reward exposure to the emerging field of allogeneic cell therapy.
Momentum investorMixed fitMomentum is highly dependent on positive clinical data readouts and sector sentiment.
Value investorWeak fitThe lack of commercial products and current operating losses make this unsuitable for traditional value metrics.
Dividend investorWeak fitThe company does not pay dividends and requires all cash for R&D operations.
Low-risk investorWeak fitThe inherent volatility of clinical-stage biotech poses significant risk to capital.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighClinical-stage biotech stocks often experience sharp price swings based on trial results and regulatory news.
Valuation riskHighValuations are highly speculative as they depend on future potential success rather than current earnings.
Competition risk (Cell Therapy)Medium / highCompetition from large, well-capitalized firms could limit the commercial potential of ARTVs therapies.
Business qualityMediumAs a pre-revenue company, business quality is defined by the strength of the R&D pipeline and execution capability.
Dividend incomeLow / noneInvestors should expect no dividend income for the foreseeable future.
Execution riskHighSuccessfully navigating clinical trials and regulatory approval processes is complex and uncertain.

Price Behavior

Strong Uptrend
PRICE PATH

Strong Uptrend

The stock has maintained a strong upward price trend across the last three quarters.

Extreme Price Shocks
PRICE STABILITY

Extreme Price Shocks

The stock has experienced exceptionally large and disruptive price movements during the period.

Analysis of Past Performance

Type Stock
Historic Profit 4.13%
Avg. Invested days 24
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 2.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 09/24/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
ARTV receives a 2-star rating, supported by solid analyst coverage. The rating is constrained by weak unit economics, soft quantitative characteristics, and weak price momentum.

Company Fundamentals

★★★★★
ARTV has moderate overall fundamentals (3 stars), with moderate financial health, weak growth momentum, and solid ownership. In FY2025 versus FY2024, growth and ownership metrics are mixed: negative earnings growth (-43.4%), soft cash generation (FCF margin 0.0%), negative revenue growth (-100.0%).

Financial Health Rating

★★★★★
ARTV's financial health is supported by strong efficiency, including operating-expense and cost-of-revenue discipline (opex 0.0% of revenue). Profitability is weak (1 stars), which helps explain the 3-star overall score.

Growth Momentum Score

★★★★★
ARTV's growth profile is soft, with the least-weak measure being free-cash-flow growth at -42.5% FY2025 versus FY2024. By comparison, while revenue growth (-100.0%, negative) and earnings growth (-43.4%, negative) hold the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 84.2% and approximately 39.8% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 15.31% supports management-shareholder alignment.

Top 5 Institutional Investors

RA Capital Management, LLC 20.15%
5AM Venture Management, LLC 4.81%
Caligan Partners LP 3.55%
VR Adviser, LLC 3.29%
Samsara BioCapital, LLC 1.95%

Unit Economics (Per $1K Revenue)

★★★★★
ARTV generates approximately $-0 of gross profit, $-0 of operating income, and $-0 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Strong cash conversion and healthy margins support the rating, although capital efficiency remains below the highest tier.

Economic Dimensions

★★★★★
Effective Tax Rate: 0.00%

Quantitative Style Profile

★★★★★
ARTV has a High Volatility Profile profile. Weak momentum is the primary drawback, while valuation that is moderately attractive rather than deeply discounted.

Style Classification

Quality Focused

High VolatilitySmall / Mid Cap RiskShort Squeeze Risk

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 366.19M USD
Price to earnings Ratio -
1Y Target Price 35.8
Price to earnings Ratio -
1Y Target Price 35.8
Volume (30-day avg) 396.5K shares
Beta 2.2
52 Weeks Range 2.71 - 14.53
Updated Date 09/24/2026
52 Weeks Range 2.71 - 14.53
Updated Date 09/24/2026
Dividends yield (FY) -
Basic EPS (TTM) -3.23

How Company Makes Money

Business areaWhat it includesRetail investor read
Cell Therapy R&DClinical development of AB-101 and other pipeline candidates.The company does not currently have commercial products; value is derived from future drug development success.
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Valuation

Trailing PE -
Forward PE -
Enterprise Value 37.40M
Price to Sales(TTM) 8.11
Enterprise Value 37.40M
Price to Sales(TTM) 8.11
Enterprise Value to Revenue 7.54
Enterprise Value to EBITDA -
Shares Outstanding 48.89M
Shares Floating 19.43M
Shares Outstanding 48.89M
Shares Floating 19.43M
Percent Insiders 15.31
Percent Institutions 84.16

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Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

About Artiva Biotherapeutics, Inc. Common Stock

Exchange NASDAQ
Headquarters San Diego, CA, United States
IPO Launch date 2024-07-19
CEO, Principal Financial & Accounting Officer and Director Dr. Fred Aslan M.D.
Sector Healthcare
Industry Biotechnology
Full time employees 115
Full time employees 115

Artiva Biotherapeutics, Inc., a clinical-stage biotechnology company, focuses on developing natural killer (NK) cell-based therapies for patients suffering from autoimmune diseases and cancers. Its lead product candidate includes AlloNK, an off-the-shelf NK cell therapy for patients with autoimmune diseases and cancers, such as rheumatoid arthritis, systemic lupus erythematosus, lupus nephritis, rheumatoid arthritis, pemphigus vulgaris, the anti-neutrophil cytoplasmic antibody -associated vasculitis subtypes granulomatosis with polyangiitis/microscopic polyangiitis, and B-cell-non-Hodgkin lymphoma. The company also develops AB-201, an allogeneic anti- human epidermal growth factor receptor 2 targeting chimeric antigen receptor (CAR)-NK cell product candidate for the treatment of various solid tumors, such as breast, gastric and esophageal, and bladder cancers; and AB-205, an allogeneic anti-CD5 CAR-NK cell product candidate for the treatment of hematological malignancies. Artiva Biotherapeutics, Inc. was incorporated in 2019 and is headquartered in San Diego, California.