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Upturn stock ratingUpturn stock rating
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Alterity Therapeutics Ltd (ATHE)

Upturn stock ratingUpturn stock rating
$3.76
Last Close (24-hour delay)
Profit since last BUY-17.72%
upturn advisory
WEAK BUY
BUY since 28 days
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
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Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
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  • YEAR
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Upturn Advisory Summary

03/11/2025: ATHE (1-star) has a low Upturn Star Rating. Not recommended to BUY.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

3 Analysts rated it

Limited analyst coverage, niche firm, research info may be scarce.

1 Year Target Price $11

1 Year Target Price $11

Analysts Price Target For last 52 week
$11Target price
Low$1
Current$3.76
high$5.87

Analysis of Past Performance

Type Stock
Historic Profit -54.46%
Avg. Invested days 23
Today’s Advisory WEAK BUY
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 03/11/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 61.31M USD
Price to earnings Ratio -
1Y Target Price 11
Price to earnings Ratio -
1Y Target Price 11
Volume (30-day avg) 3
Beta 0.72
52 Weeks Range 1.00 - 5.87
Updated Date 07/1/2025
52 Weeks Range 1.00 - 5.87
Updated Date 07/1/2025
Dividends yield (FY) -
Basic EPS (TTM) -1.75

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -469.68%

Management Effectiveness

Return on Assets (TTM) -78.37%
Return on Equity (TTM) -155.77%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 55097901
Price to Sales(TTM) 16.46
Enterprise Value 55097901
Price to Sales(TTM) 16.46
Enterprise Value to Revenue 113.99
Enterprise Value to EBITDA 0.75
Shares Outstanding 14803400
Shares Floating 4310429916
Shares Outstanding 14803400
Shares Floating 4310429916
Percent Insiders -
Percent Institutions 1.6

Analyst Ratings

Rating 2
Target Price 11
Buy 1
Strong Buy 1
Buy 1
Strong Buy 1
Hold 1
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Alterity Therapeutics Ltd

stock logo

Company Overview

overview logo History and Background

Alterity Therapeutics Ltd, formerly Prana Biotechnology, focuses on developing treatments for neurodegenerative diseases. Founded to commercialize research, it has shifted focus to iron-related neurodegeneration.

business area logo Core Business Areas

  • Drug Development: Developing novel therapies for neurodegenerative diseases, specifically focusing on iron chaperones and their role in disease progression.
  • Clinical Trials: Conducting clinical trials to evaluate the safety and efficacy of its drug candidates, such as ATH434 for Multiple System Atrophy (MSA).

leadership logo Leadership and Structure

The leadership team consists of a CEO (David Stamler, MD), a Chief Medical Officer, and a board of directors. The organizational structure is typical of a biotech company, with departments for research, clinical development, and administration.

Top Products and Market Share

overview logo Key Offerings

  • ATH434: ATH434 is Alterity's lead drug candidate, an iron chaperone being developed for Multiple System Atrophy (MSA). There is no market share data available, as it's in clinical development. Competitors include companies developing symptomatic treatments and disease-modifying therapies for MSA, such as those working on alpha-synuclein aggregation.

Market Dynamics

industry overview logo Industry Overview

The industry is characterized by high unmet need for effective treatments for neurodegenerative diseases. Significant investment in research and development drives innovation in this field.

Positioning

Alterity is positioned as a company focused on addressing iron dysregulation in neurodegenerative diseases, offering a potentially disease-modifying approach. Its competitive advantage lies in its iron chaperone technology.

Total Addressable Market (TAM)

The TAM for neurodegenerative disease treatments is estimated to be billions of dollars. Alterity is positioned to capture a share of this market if ATH434 proves successful.

Upturn SWOT Analysis

Strengths

  • Novel iron chaperone technology
  • Focus on disease-modifying therapies
  • Lead candidate in clinical development for MSA

Weaknesses

  • Single lead product
  • High dependence on clinical trial success
  • Limited financial resources

Opportunities

  • Positive clinical trial results
  • Partnerships with larger pharmaceutical companies
  • Expansion to other neurodegenerative diseases

Threats

  • Clinical trial failures
  • Competition from other therapies
  • Regulatory hurdles

Competitors and Market Share

competitor logo Key Competitors

  • There are no key competitors that have the same drug target. Other companies with neurodegenerative disease programs: BIIB
  • SNY
  • ABBV

Competitive Landscape

Alterity has a novel approach, but it is a small player compared to larger pharmaceutical companies developing treatments for neurodegenerative diseases.

Growth Trajectory and Initiatives

Historical Growth: Historically, growth has been dependent on clinical trial progression and related fund raising events.

Future Projections: Future growth depends on the success of ATH434 and the ability to secure partnerships or further funding.

Recent Initiatives: Recent initiatives include advancing ATH434 through clinical trials and exploring other potential applications of its technology.

Summary

Alterity Therapeutics is a development-stage biotech company with a focus on iron chaperones for neurodegenerative diseases. Its success hinges on the clinical development of ATH434, its lead product. While it has a novel approach, it faces risks associated with clinical trials and competition from larger pharmaceutical companies. Funding and partnerships are critical for its future.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company website
  • SEC filings
  • Analyst reports
  • Clinical trial registries

Disclaimers:

This analysis is based on available information and is not financial advice. Investment in biotechnology companies is inherently risky.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Alterity Therapeutics Ltd

Exchange NASDAQ
Headquaters Melbourne, VIC, Australia
IPO Launch date 2002-09-05
CEO -
Sector Healthcare
Industry Biotechnology
Full time employees 10
Full time employees 10

Alterity Therapeutics Limited engages in the research and development of therapeutic drugs to treat Alzheimer's disease, Huntington disease, Parkinson's disease, and other neurological disorders in Australia. The company's lead drug candidate is ATH434, a small molecule drug candidate that has completed Phase I clinical trial for the treatment of Parkinson's disease. It is also developing ATH434-201, which is in Phase II clinical trial to treat multiple system atrophy early stage; ATH434-202 that is in Phase II clinical trial to treat multiple system atrophy; and PBT2 that has completed Phase 2a clinical trial to treat Alzheimer's disease. The company was formerly known as Prana Biotechnology Limited and changed its name to Alterity Therapeutics Limited in April 2019. Alterity Therapeutics Limited was incorporated in 1997 and is headquartered in Melbourne, Australia.