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Upturn AI Summary - About
Alterity Therapeutics Ltd(ATHE)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Stock price based on last close Advisory Performance History (Simulated)
Upturn Advisory & Investor View for ATHE
11/06/2026: ATHE (1-star) is currently NOT-A-BUY. Pass it for now.
Alterity Therapeutics is a clinical-stage biotechnology company focused on developing small-molecule treatments for neurodegenerative conditions, particularly Parkinsonian disorders. Its primary investment story hinges on the potential success of its lead candidate, ATH434, and its proprietary iron-chaperone technology. While the company has a specialized focus, it faces significant risks including the lack of commercialized products, a history of operating losses, and the binary nature of clinical trial success. It is best suited for speculative investors comfortable with high volatility and long-term development risks. Investors should closely monitor clinical trial updates and the company's ability to manage its cash runway through future capital requirements.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Weak fit | The company lacks the revenue growth or commercial products typically sought by growth investors. |
| Momentum investor | Weak fit | Momentum is limited by the binary risk of clinical trials and historical volatility. |
| Value investor | Weak fit | The company is a pre-revenue development stage entity, making traditional value metrics inapplicable. |
| Dividend investor | Weak fit | The company pays no dividends and is not expected to do so in the foreseeable future. |
| Low-risk investor | Weak fit | The high binary risk and potential for volatility make this unsuitable for low-risk portfolios. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | Clinical-stage stocks often experience extreme price swings based on trial data announcements. |
| Valuation risk | High | Valuation is speculative and entirely dependent on future regulatory outcomes. |
| Competition risk (Neurology/Biotech) | High | Larger competitors possess vast resources that can overshadow smaller players. |
| Business quality | Medium | The company is in an early developmental stage with no established revenue stream. |
| Dividend income | Low / none | No income potential exists for investors. |
| Execution risk | High | Success depends on clinical trial precision and regulatory approvals. |
Price Behavior
Downtrend
The stock has experienced a sustained decline in price over recent periods.
Choppy
The stock has experienced frequent reversals and pronounced short-term price swings.
Analysis of Past Performance
Type Stock | Historic Profit -31.99% | Avg. Invested days 18 | Today’s Advisory PASS |
Upturn Advisory Rating  | Upturn Advisory Performance  2.0 | Stock Returns Performance  1.0 |
| Profits based on simulation | Last Close 11/06/2026 |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals
Financial Health Rating
Growth Momentum Score
Ownership
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue)
Economic Dimensions
Quantitative Style Profile
Style Classification
Quality Focused
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 42.38M USD | Price to earnings Ratio - | 1Y Target Price 13.25 |
Price to earnings Ratio - | 1Y Target Price 13.25 | ||
Volume (30-day avg) 164.5K shares | Beta -0.03 | 52 Weeks Range 2.01 - 5.89 | Updated Date 11/05/2026 |
52 Weeks Range 2.01 - 5.89 | Updated Date 11/05/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.83 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Drug Development | Clinical trial development for neurodegenerative assets. | The company does not currently earn money and relies on capital raises to fund research. |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 20.43M | Price to Sales(TTM) 11.74 |
Enterprise Value 20.43M | Price to Sales(TTM) 11.74 | ||
Enterprise Value to Revenue 113.99 | Enterprise Value to EBITDA 0.75 | Shares Outstanding 19.09M | Shares Floating 14.43M |
Shares Outstanding 19.09M | Shares Floating 14.43M | ||
Percent Insiders - | Percent Institutions 2.06 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
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