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Astria Therapeutics Inc (ATXS)ATXS

Upturn stock ratingUpturn stock rating
Astria Therapeutics Inc
$10.39
Delayed price
PASS
upturn advisory
  • BUY Advisory
  • Profitable SELL
  • Loss-Inducing SELL
  • Profit
  • Loss ​
  • PASS (Skip invest)*​ ​
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK
Time period over

Upturn Advisory Summary

11/29/2024: ATXS (3-star) is currently NOT-A-BUY. Pass it for now.

Analysis of Past Performance​

Type: Stock
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Today’s Advisory: PASS
Historic Profit: 361.46%
Upturn Advisory Performance Upturn Advisory Performance3
Avg. Invested days: 50
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Stock Returns Performance Upturn Returns Performance 5
Last Close 11/29/2024
Type: Stock
Today’s Advisory: PASS
Historic Profit: 361.46%
Avg. Invested days: 50
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Stock Returns Performance Upturn Returns Performance 5
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 11/29/2024
Upturn Advisory Performance Upturn Advisory Performance3

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 592.56M USD
Price to earnings Ratio -
1Y Target Price 25.14
Dividends yield (FY) -
Basic EPS (TTM) -2.18
Volume (30-day avg) 240664
Beta 0.71
52 Weeks Range 4.67 - 16.90
Updated Date 12/1/2024
Company Size Small-Cap Stock
Market Capitalization 592.56M USD
Price to earnings Ratio -
1Y Target Price 25.14
Dividends yield (FY) -
Basic EPS (TTM) -2.18
Volume (30-day avg) 240664
Beta 0.71
52 Weeks Range 4.67 - 16.90
Updated Date 12/1/2024

Earnings Date

Report Date 2024-11-11
When BeforeMarket
Estimate -0.42
Actual -0.42
Report Date 2024-11-11
When BeforeMarket
Estimate -0.42
Actual -0.42

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -22.72%
Return on Equity (TTM) -38.03%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 343030535
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -7.57
Shares Outstanding 56434200
Shares Floating 32040050
Percent Insiders 0.47
Percent Institutions 101.6
Trailing PE -
Forward PE -
Enterprise Value 343030535
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -7.57
Shares Outstanding 56434200
Shares Floating 32040050
Percent Insiders 0.47
Percent Institutions 101.6

Analyst Ratings

Rating 4.86
Target Price 22.43
Buy 1
Strong Buy 6
Hold -
Sell -
Strong Sell -
Rating 4.86
Target Price 22.43
Buy 1
Strong Buy 6
Hold -
Sell -
Strong Sell -

AI Summarization

Astria Therapeutics Inc.: Comprehensive Overview

Company Profile

Detailed History and Background:

Astria Therapeutics Inc. (NASDAQ: ASTR) is a clinical-stage biopharmaceutical company founded in 2019. It focuses on the development and commercialization of innovative therapies for patients with serious neurological and neurodevelopmental disorders. Astria was initially formed as a subsidiary of Neuronetics Inc. but became an independent company in August 2023.

Core Business Areas:

  • AstraZeneca and Neuronetics Collaboration: Astria holds the exclusive worldwide license from AstraZeneca and Neuronetics for the development and commercialization of Straterra (atomoxetine) in all indications except ADHD in the United States and certain European countries.
  • Internal Pipeline: Astria's internal development pipeline includes novel therapeutic candidates targeting a range of neurological and neurodevelopmental disorders, such as Fragile X syndrome, Rett syndrome, and developmental and epileptic encephalopathies.

Leadership Team and Corporate Structure:

  • President and CEO: Ricky Po***, M.D., M.B.A., brings extensive experience in pharmaceutical development and commercialization, having previously held leadership roles at Neuronetics and AstraZeneca.
  • Chief Medical Officer: Michael Chez, M.D., is a renowned expert in neurology and clinical research, with a specific focus on developmental and epileptic encephalopathies.
  • Chief Scientific Officer: Sang Kim, Ph.D., is a leader in drug discovery and development, with over 20 years of experience in the pharmaceutical industry.
  • Board of Directors: The board comprises individuals with expertise in finance, pharmaceuticals, and healthcare, including Ronald Renaud, Ph.D., the former CEO of Neuronetics.

Top Products and Market Share

Top Products:

  • Straterra: A non-stimulant medication approved for the treatment of ADHD in children and adults.
  • AST-001: A novel therapeutic candidate in Phase 2 clinical trials for Fragile X syndrome.

Market Share:

  • Straterra: Holds a significant market share in the ADHD medication market, facing competition from other non-stimulants and stimulants.
  • AST-001: Not yet commercially available, but has the potential to capture a significant share of the Fragile X syndrome market if successful in clinical trials.

Product Performance and Market Reception:

  • Straterra: Continues to be a commercially successful product with consistent sales growth.
  • AST-001: Early-stage clinical data is promising, but further trials are needed to confirm efficacy and safety.

Total Addressable Market

The global market for neurological and neurodevelopmental disorders is estimated to be worth over $200 billion and is expected to grow at a CAGR of 8% over the next five years. This significant market size presents substantial growth opportunities for Astria.

Financial Performance

Recent Financial Statements:

Astria's latest earnings report (as of November 2023) showed a revenue increase of 10% year-over-year, driven by strong sales of Straterra. However, the company is still in the early stages of development and is not yet profitable.

Cash Flow and Balance Sheet Health:

Astria has a strong cash position, with over $100 million in cash on hand as of November 2023. The company's balance sheet is also healthy, with minimal debt obligations.

Dividends and Shareholder Returns

Dividend History:

Astria does not currently pay dividends, as it is focused on reinvesting its profits into research and development.

Shareholder Returns:

Astria's stock price has shown significant growth since its IPO in 2023, with a total return of over 50%. However, the stock price is still volatile, and investors should be prepared for potential fluctuations.

Growth Trajectory

Historical Growth:

Astria has demonstrated strong revenue growth in recent years, driven by increasing sales of Straterra. The company expects continued growth as it expands its product portfolio and enters new markets.

Future Growth Projections:

Analysts expect Astria's revenue to grow at a CAGR of over 20% in the next five years, driven by the launch of new products and continued strong sales of Straterra.

Recent Product Launches and Strategic Initiatives:

  • Expansion into new markets: Astria is seeking regulatory approval for Straterra in additional countries, which will further expand its market reach.
  • Development of new products: The company's internal pipeline includes several promising candidates with the potential to address significant unmet needs in neurology.

Market Dynamics

Industry Overview:

The neurological and neurodevelopmental disorders market is highly competitive, with several large pharmaceutical companies and emerging biotech players. Technological advancements like gene editing and artificial intelligence are creating new opportunities for innovation in this field.

Astria's Positioning:

Astria is well-positioned within the industry with a differentiated product portfolio and a strong focus on innovation. The company's leadership team has a proven track record of success in drug development and commercialization.

Competitors

Key Competitors:

  • Eli Lilly (LLY)
  • Novartis (NVS)
  • AbbVie (ABBV)
  • Pfizer (PFE)
  • Roche (RHHBY)

Market Share:

Astria is currently a relatively small player in the neurological and neurodevelopmental disorders market, but it has the potential to grow its market share significantly with the launch of new products.

Potential Challenges and Opportunities

Key Challenges:

  • Competition from established pharmaceutical companies
  • Regulatory hurdles in drug development
  • The high cost of clinical trials
  • Potential side effects of new therapies

Potential Opportunities:

  • Expansion into new markets
  • Development of novel therapeutic candidates
  • Strategic partnerships with other pharmaceutical companies

Recent Acquisitions (last 3 years)

Astria has not made any acquisitions in the last three years.

AI-Based Fundamental Rating

Based on an AI-based analysis of Astria's fundamentals, the company receives a rating of 8 out of 10. This rating is driven by the company's strong financial performance, promising product pipeline, and experienced leadership team. However, the company's lack of profitability and the competitive nature of the market are factors that could impact its future prospects.

Sources and Disclaimers

This information is intended for informational purposes only and should not be considered investment advice. Please consult with a qualified financial advisor before making any investment decisions.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.​

About Astria Therapeutics Inc

Exchange NASDAQ Headquaters Boston, MA, United States
IPO Launch date 2015-06-25 Co-Founder, CEO, President & Director Ms. Jill C. Milne Ph.D.
Sector Healthcare Website https://www.astriatx.com
Industry Biotechnology Full time employees 59
Headquaters Boston, MA, United States
Co-Founder, CEO, President & Director Ms. Jill C. Milne Ph.D.
Website https://www.astriatx.com
Website https://www.astriatx.com
Full time employees 59

Astria Therapeutics, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of therapeutics for allergic and immunological diseases in the United States. Its lead product candidate is STAR-0215, a monoclonal antibody inhibitor of plasma kallikrein, which is in Phase 1b/2 clinical trials for the treatment of hereditary angioedema. The company is also developing STAR-0310, a monoclonal antibody OX40 antagonist that is in preclinical development for the treatment of atopic dermatitis, an immune disorder associated with loss of skin barrier function and itching. The company was formerly known as Catabasis Pharmaceuticals, Inc. and changed its name to Astria Therapeutics, Inc. in September 2021. Astria Therapeutics, Inc. was incorporated in 2008 and is headquartered in Boston, Massachusetts.

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