Aura Biosciences Inc logo

Aura Biosciences Inc(AURA)

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ADVISORIES YOU CAN VERIFY
QUALITY SIGNAL
2-STAR RATING
PASS
LAST CLOSE
$6.15
09/24/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
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Upturn Advisory & Investor View for AURA

09/24/2026: AURA (2-star) is currently NOT-A-BUY. Pass it for now.

Aura Biosciences is a clinical-stage biotechnology company focused on developing targeted, vision-sparing therapies for ocular and other solid tumor cancers using its proprietary VDC platform. The company's main strength lies in its innovative drug delivery technology and its focus on underserved oncology markets. Its primary growth story centers on the potential for Bel-sar to become a new standard of care for choroidal melanoma. However, the firm faces significant execution and binary risks, as it currently lacks commercial revenue and depends entirely on successful clinical outcomes and regulatory approvals. Aura is best suited for growth-oriented investors who can tolerate high volatility and long-term development risks.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorMixed fitAura offers high growth potential contingent on clinical success but carries significant binary risk.
Momentum investorMixed fitMomentum depends heavily on clinical data announcements which can cause sharp, volatile price movements.
Value investorWeak fitThe company lacks current earnings or revenue, making traditional value metrics inapplicable.
Dividend investorWeak fitAura is a clinical-stage biotech and does not pay dividends.
Low-risk investorWeak fitHigh volatility and the risks associated with drug development are unsuitable for low-risk portfolios.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighClinical-stage biotech stocks often experience sharp fluctuations based on trial results and funding news.
Valuation riskMedium / highValuations are highly speculative as they are based on future potential rather than current financial performance.
Competition risk (oncology)MediumEstablished players have more resources to develop competing therapies.
Business qualityMediumWhile the platform is innovative, the lack of commercialized products limits current franchise strength.
Dividend incomeLow / noneThe company is in an investment phase and does not generate income for shareholders.
Execution riskHighThe company must successfully navigate complex clinical and regulatory pathways to reach commercialization.

Price Behavior

Strong Uptrend
PRICE PATH

Strong Uptrend

The stock has maintained a strong upward price trend across the last three quarters.

Choppy
PRICE STABILITY

Choppy

The stock has experienced frequent reversals and pronounced short-term price swings.

Analysis of Past Performance

Type Stock
Historic Profit -58.54%
Avg. Invested days 21
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 2.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 09/24/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
AURA receives a 3-star rating, supported by solid analyst coverage. The rating is constrained by weak unit economics, and weak price momentum.

Company Fundamentals

★★★★★
AURA has moderate overall fundamentals (3 stars), with moderate financial health, moderate growth momentum, and solid ownership. In FY2025 versus FY2024, growth and ownership metrics are mixed: negative earnings growth (-22.2%), soft cash generation (FCF margin 0.0%), slightly negative revenue growth (+0.0%).

Financial Health Rating

★★★★★
AURA's financial health is supported by strong efficiency, including operating-expense and cost-of-revenue discipline (opex 0.0% of revenue). Profitability is weak (1 stars), which helps explain the 3-star overall score.

Growth Momentum Score

★★★★★
AURA's growth profile is soft, with the least-weak measure being revenue growth at +0.0% FY2025 versus FY2024. By comparison, while earnings growth (-22.2%, negative) and free-cash-flow growth (-5.1%, negative) hold the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 94.3% and approximately 76.8% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 2.70% provides only moderate management-shareholder alignment.

Top 5 Institutional Investors

TCG Crossover Management, LLC 9.21%
Matrix Capital Management Company, LLC 6.69%
Long Focus Capital Management, LLC 4.95%
Frazier Life Sciences Management, L.P. 4.93%
Adage Capital Partners Gp LLC 4.48%

Unit Economics (Per $1K Revenue)

★★★★★
AURA generates approximately $0 of gross profit, $-0 of operating income, and $-0 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Strong cash conversion and healthy margins support the rating, although capital efficiency remains below the highest tier.

Economic Dimensions

★★★★★
Effective Tax Rate: -0.10% (Tax Credit)

Quantitative Style Profile

★★★★★
AURA has a liquid, relatively low-volatility profile. Weak momentum is the primary drawback.

Style Classification

Quality Focused

Low VolatilitySmall / Mid Cap RiskShort Squeeze RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 624.30M USD
Price to earnings Ratio -
1Y Target Price 16.6
Price to earnings Ratio -
1Y Target Price 16.6
Volume (30-day avg) 936.2K shares
Beta 0.4
52 Weeks Range 4.73 - 9.54
Updated Date 09/24/2026
52 Weeks Range 4.73 - 9.54
Updated Date 09/24/2026
Dividends yield (FY) -
Basic EPS (TTM) -1.73

How Company Makes Money

Business areaWhat it includesRetail investor read
Clinical DevelopmentResearching and testing Bel-sar and other VDC candidates.The company currently spends money to develop drugs and does not have product sales.
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Valuation

Trailing PE -
Forward PE -
Enterprise Value 316.02M
Price to Sales(TTM) -
Enterprise Value 316.02M
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -5.68
Shares Outstanding 103.70M
Shares Floating 79.63M
Shares Outstanding 103.70M
Shares Floating 79.63M
Percent Insiders 2.7
Percent Institutions 94.29

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Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

About Aura Biosciences Inc

Exchange NASDAQ
Headquarters Boston, MA, United States
IPO Launch date 2021-10-29
President, CEO & Director Ms. Natalie C. Holles
Sector Healthcare
Industry Biotechnology
Full time employees 113
Full time employees 113

Aura Biosciences, Inc., a clinical-stage biotechnology company, develops precision therapies to treat solid tumors. The company's proprietary platform enables the targeting of a range of solid tumors using virus-like particles conjugated with drugs or loaded with nucleic acids to create virus-like drug conjugates. Its lead candidate is bel-sar, which is in late-stage clinical development for the treatment of patients with primary choroidal melanoma and other ocular oncology indications, as well as in early-stage clinical development in bladder cancer. It focuses on assessing the safety and efficacy of bel-sar in treating a range of other solid tumors, including bladder cancer. The company was incorporated in 2009 and is headquartered in Boston, Massachusetts.