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Azitra Inc (AZTR)


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Upturn Advisory Summary
10/30/2025: AZTR (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $4.5
1 Year Target Price $4.5
| 0 | Strong Buy | 
| 1 | Buy | 
| 0 | Hold | 
| 0 | Sell | 
| 0 | Strong Sell | 
Analysis of Past Performance
|  Type  Stock |  Historic Profit  0% |  Avg. Invested days  0 |  Today’s Advisory  PASS  | 
|  Upturn Star Rating   |  Upturn Advisory Performance   1.0 |  Stock Returns Performance   1.0 | 
|  Profits based on simulation |  Last Close 10/30/2025 | 
Key Highlights
|  Company Size  Small-Cap Stock  |  Market Capitalization  2.69M  USD  |  Price to earnings Ratio  0.02  |  1Y Target Price  4.5  | 
|  Price to earnings Ratio  0.02  |  1Y Target Price  4.5  | ||
|  Volume (30-day avg)  1  |  Beta  -1.69  |  52 Weeks Range  0.47 - 4.33  |  Updated Date  10/30/2025  | 
|  52 Weeks Range  0.47 - 4.33  |  Updated Date  10/30/2025  | ||
|  Dividends yield (FY)  -  |  Basic EPS (TTM)  26.97  | 
Earnings Date
|  Report Date  -  |  When  -  |  Estimate  -  |  Actual  -  | 
Profitability
|  Profit Margin  -  |  Operating Margin (TTM)  -  | 
Management Effectiveness
|  Return on Assets (TTM)  -180.76%  |  Return on Equity (TTM)  -473.31%  | 
Valuation
|  Trailing PE  0.02  |  Forward PE  -  |  Enterprise Value  3515590  |  Price to Sales(TTM)  438.62  | 
|  Enterprise Value  3515590  |  Price to Sales(TTM)  438.62  | ||
|  Enterprise Value to Revenue  220.15  |  Enterprise Value to EBITDA  -0.39  |  Shares Outstanding  5404968  |  Shares Floating  3506751  | 
|  Shares Outstanding  5404968  |  Shares Floating  3506751  | ||
|  Percent Insiders  0.52  |  Percent Institutions  1.71  | 
 Upturn AI SWOT
 Upturn AI SWOT 
Azitra Inc
Company Overview
 History and Background
 History and Background 
Azitra, Inc. is a clinical-stage medical dermatology company focused on developing therapies to protect skin health using its proprietary platform that combines a deep understanding of the skin microbiome with innovative genetic engineering. They were founded in 2014 and went public through a special-purpose acquisition company (SPAC) merger in 2023.
 Core Business Areas
 Core Business Areas 
- Therapeutic Development: Azitra focuses on developing genetically engineered bacteria to treat skin conditions and diseases.
- Research and Development: The company invests in research to expand its understanding of the skin microbiome and develop new therapeutic candidates.
 Leadership and Structure
 Leadership and Structure 
Travis Whitfill is the CEO. The company has a board of directors and is structured around research, development, and clinical operations.
Top Products and Market Share
 Key Offerings
 Key Offerings 
- ATR-12: ATR-12 is a genetically engineered strain of Staphylococcus epidermidis being developed for Netherton Syndrome. Currently in phase 1b trials. Competitors include companies developing gene therapies and biologics for similar genetic skin disorders, such as Novartis.
- ATR-04: ATR-04 is being developed to treat papulopustular rosacea. Competitors include companies focused on topical treatments for rosacea. Precise market share data is not currently available.
Market Dynamics
 Industry Overview
 Industry Overview 
The medical dermatology industry is growing, driven by increasing awareness of skin conditions and the development of new treatments. The market is competitive, with a mix of established pharmaceutical companies and smaller biotech firms.
Positioning
Azitra is positioned as an innovator in the skin microbiome therapeutic space, with a focus on genetically engineered bacteria. Their competitive advantage lies in their proprietary platform and focus on targeted therapies.
Total Addressable Market (TAM)
The total addressable market for Netherton Syndrome and rosacea therapeutics is estimated to be in the billions of dollars. Azitra is positioned to capture a portion of this market with its novel approach, however, this is highly speculative at this early stage.
Upturn SWOT Analysis
Strengths
- Proprietary platform technology
- Focus on unmet medical needs
- Strong scientific team
- Potential for first-in-class therapies
Weaknesses
- Early stage of development
- High risk associated with novel therapies
- Dependence on external funding
- Limited clinical data
Opportunities
- Expanding pipeline of therapeutic candidates
- Partnering with larger pharmaceutical companies
- Securing regulatory approvals
- Addressing additional skin conditions
Threats
- Competition from established companies
- Regulatory hurdles
- Clinical trial failures
- Intellectual property challenges
Competitors and Market Share
 Key Competitors
 Key Competitors 
- NOVN
- SNY
- LLY
Competitive Landscape
Azitra competes with established pharmaceutical companies and smaller biotech firms in the dermatology space. Their advantage lies in their unique approach to targeting the skin microbiome.
Growth Trajectory and Initiatives
Historical Growth: Azitra's historical growth has been focused on preclinical and early-stage clinical development.
Future Projections: Future growth is dependent on successful clinical trials and regulatory approvals. Analyst estimates are unavailable.
Recent Initiatives: Recent initiatives include advancing ATR-12 into Phase 1b trials and expanding the pipeline with ATR-04.
Summary
Azitra is an early-stage biotech company with a novel approach to treating skin diseases using engineered bacteria. Their success depends on positive clinical trial results and securing regulatory approvals. While their technology is promising, they face significant risks associated with drug development and competition from established players. More information on their market cap will impact the fundamental rating.
Similar Stocks
Sources and Disclaimers
Data Sources:
- Company Website
- SEC Filings
- Press Releases
- Industry Reports
Disclaimers:
This analysis is based on publicly available information and should not be considered financial advice. The information provided is not guaranteed to be accurate or complete. Investing in early-stage biotech companies involves significant risks.
 AI Summarization is directionally correct and might not be accurate.
 AI Summarization is directionally correct and might not be accurate. 
 Summarized information shown could be a few years old and not current.
 Summarized information shown could be a few years old and not current. 
 Fundamental Rating based on AI could be based on old data.
 Fundamental Rating based on AI could be based on old data. 
 AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
 AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action. 
About Azitra Inc
|  Exchange  NYSE MKT  |  Headquaters  Branford, CT, United States  | ||
|  IPO Launch date  2023-06-16  |  President, CEO & Director  Mr. Francisco D. Salva  | ||
|  Sector  Healthcare  |  Industry  Biotechnology  |  Full time employees  12  |  Website  https://azitrainc.com  | 
|  Full time employees  12  |  Website  https://azitrainc.com  | ||
Azitra, Inc., an early-stage clinical biopharmaceutical company, develops therapies for precision dermatology using engineered proteins and live biotherapeutic products to treat skin diseases. It develops ATR-12, a genetically modified strain of S. epidermidis, which is in Phase Ib clinical trial for treating Netherton syndrome, a skin disease. The company also develops ATR-04, a genetically modified strain of S. epidermidis that is in Phase 1/2 clinical trial for treating the papulopustular rash experienced by cancer patients undergoing epidermal growth factor receptor inhibitor; and ATR-01, an engineered recombinant human filaggrin protein for treating ichthyosis vulgaris, a skin disease. It has a collaboration with Bayer. The company was incorporated in 2014 and is based in Branford, Connecticut.

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