Biofrontera Inc logo

Biofrontera Inc(BFRI)

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ADVISORIES YOU CAN VERIFY
QUALITY SIGNAL
1-STAR RATING
PASS
LAST CLOSE
$1.15
09/23/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
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Upturn Advisory & Investor View for BFRI

09/23/2026: BFRI (1-star) is currently NOT-A-BUY. Pass it for now.

Biofrontera Inc. is a specialized biopharmaceutical company focused on the U.S. commercialization of dermatological treatments, most notably Ameluz for actinic keratosis. The company's primary strength lies in its targeted approach to the photodynamic therapy market and its established FDA-approved portfolio. While it has successfully brought a product to market, its investment story is centered on scaling sales and expanding clinical indications to drive growth. Key risks include intense competition from larger pharmaceutical firms, reliance on a single core product, and the need to achieve sustained profitability. This stock may suit investors willing to accept the volatility associated with small-cap biotech, particularly those monitoring product adoption trends.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorMixed fitThe company offers growth potential through product adoption, but carries risks associated with early-stage commercialization.
Momentum investorMixed fitMomentum investment is conditional on sustained revenue growth signals and positive market sentiment.
Value investorWeak fitThe company's lack of consistent profitability makes it less suitable for traditional value-based investment strategies.
Dividend investorWeak fitThe company does not pay dividends and focuses on reinvesting cash flow into commercial operations.
Low-risk investorWeak fitThe inherent volatility of small-cap pharmaceutical stocks is generally unsuitable for low-risk investors.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighSmall-cap pharmaceutical stocks often experience significant price swings based on clinical or market news.
Valuation riskMedium / highDetermining fair value for companies with developing revenue streams involves significant uncertainty.
Competition risk (Large Pharma)HighThe company competes with established firms that have greater resources and market access.
Business qualityMediumThe business relies heavily on a limited product portfolio, concentrating operational risk.
Dividend incomeLow / noneThere is no current expectation of income through dividends.
Execution riskMedium / highSuccess depends on the effective execution of commercial strategies and market penetration.

Price Behavior

Strong Uptrend
PRICE PATH

Strong Uptrend

The stock has maintained a strong upward price trend across the last three quarters.

Extreme Price Shocks
PRICE STABILITY

Extreme Price Shocks

The stock has experienced exceptionally large and disruptive price movements during the period.

Analysis of Past Performance

Type Stock
Historic Profit -76.8%
Avg. Invested days 23
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 2.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 09/23/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
BFRI receives a 3-star rating, supported by solid analyst coverage. The rating is constrained by soft unit economics, and weak price momentum.

Company Fundamentals

★★★★★
BFRI has moderate overall fundamentals (3 stars), with soft financial health, moderate growth momentum, and solid ownership. In FY2025 versus FY2024, strong earnings growth (+40.7%) and solid revenue growth (+11.8%) are partially offset by soft cash generation (FCF margin -32.0%), soft profitability (net margin -25.3%).

Financial Health Rating

★★★★★
BFRI's financial health is supported by moderate liquidity, including working-capital and asset support (WC/assets 21.7%). Cash strength is soft (2 stars), which helps explain the 2-star overall score.

Growth Momentum Score

★★★★★
Earnings growth is BFRI's strongest growth driver at +40.7% FY2025 versus FY2024 (strong, 5 stars). By comparison, revenue growth (+11.8%, solid) is also solid, while free-cash-flow growth (-29.4%, negative) holds the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 20.7% and approximately 79.7% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 11.99% supports management-shareholder alignment.

Top 5 Institutional Investors

Rosalind Advisors, Inc. 7.84%
AIGH Capital Management, LLC 4.98%
Geode Capital Management, LLC 0.74%
Citadel Advisors Llc 0.71%
Vanguard Fiduciary Trust Co 0.42%

Unit Economics (Per $1K Revenue)

★★★★★
BFRI generates approximately $787 of gross profit, $-219 of operating income, and $-320 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Strong cash conversion and healthy margins support the rating, although capital efficiency remains below the highest tier.

Economic Dimensions

★★★★★
Effective Tax Rate: -0.24% (Tax Credit)

Quantitative Style Profile

★★★★★
BFRI has a liquid profile. Weak momentum is the primary drawback.

Style Classification

Quality Focused

Value-OrientedSmall / Mid Cap RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 17.38M USD
Price to earnings Ratio -
1Y Target Price 6
Price to earnings Ratio -
1Y Target Price 6
Volume (30-day avg) 776.3K shares
Beta 0.84
52 Weeks Range 0.55 - 1.66
Updated Date 09/23/2026
52 Weeks Range 0.55 - 1.66
Updated Date 09/23/2026
Dividends yield (FY) -
Basic EPS (TTM) -0.43

How Company Makes Money

Business areaWhat it includesRetail investor read
Dermatological SalesRevenue generated from the sale of the drug Ameluz for photodynamic therapy.The company makes money by selling a specialized skin cancer treatment drug to dermatologists.

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

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Valuation

Trailing PE -
Forward PE 13
Enterprise Value 20.07M
Price to Sales(TTM) 0.38
Enterprise Value 20.07M
Price to Sales(TTM) 0.38
Enterprise Value to Revenue 0.43
Enterprise Value to EBITDA -0.79
Shares Outstanding 14.85M
Shares Floating 11.84M
Shares Outstanding 14.85M
Shares Floating 11.84M
Percent Insiders 11.99
Percent Institutions 20.72

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Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

About Biofrontera Inc

Exchange NASDAQ
Headquarters Woburn, MA, United States
IPO Launch date 2021-10-29
CEO, President & Chairman Dr. Hermann Luebbert Ph.D.
Sector Healthcare
Industry Drug Manufacturers - Specialty & Generic
Full time employees 84
Full time employees 84

Biofrontera Inc., a biopharmaceutical company, engages in the commercialization of pharmaceutical products for the treatment of dermatological conditions in the United States. It offers Ameluz, BF-RhodoLED, RhodoLED XL lamp series, and RhodoLED Lamps, which are used for the treatment of actinic keratosis, which are pre-cancerous skin lesions. The company was incorporated in 2015 and is headquartered in Woburn, Massachusetts.