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CLDX
Upturn stock ratingUpturn stock rating

Celldex Therapeutics Inc (CLDX)

Upturn stock ratingUpturn stock rating
$20.35
Last Close (24-hour delay)
Profit since last BUY-4.28%
upturn advisory
Consider higher Upturn Star rating
BUY since 11 days
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Upturn Advisory Summary

06/30/2025: CLDX (1-star) has a low Upturn Star Rating. Not recommended to BUY.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

14 Analysts rated it

Well-followed company, solid analyst reports, reliable data for confident investing.

1 Year Target Price $58.54

1 Year Target Price $58.54

Analysts Price Target For last 52 week
$58.54Target price
Low$14.4
Current$20.35
high$47

Analysis of Past Performance

Type Stock
Historic Profit -45.23%
Avg. Invested days 22
Today’s Advisory Consider higher Upturn Star rating
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 1.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 06/30/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 1.35B USD
Price to earnings Ratio -
1Y Target Price 58.54
Price to earnings Ratio -
1Y Target Price 58.54
Volume (30-day avg) 14
Beta 1.14
52 Weeks Range 14.40 - 47.00
Updated Date 06/29/2025
52 Weeks Range 14.40 - 47.00
Updated Date 06/29/2025
Dividends yield (FY) -
Basic EPS (TTM) -2.7

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -9027.19%

Management Effectiveness

Return on Assets (TTM) -16.88%
Return on Equity (TTM) -23.2%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 677276149
Price to Sales(TTM) 178.22
Enterprise Value 677276149
Price to Sales(TTM) 178.22
Enterprise Value to Revenue 89.6
Enterprise Value to EBITDA -17.34
Shares Outstanding 66394200
Shares Floating 56358751
Shares Outstanding 66394200
Shares Floating 56358751
Percent Insiders 0.32
Percent Institutions 113.13

Analyst Ratings

Rating 4
Target Price 58.54
Buy 2
Strong Buy 10
Buy 2
Strong Buy 10
Hold 2
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Celldex Therapeutics Inc

stock logo

Company Overview

overview logo History and Background

Celldex Therapeutics Inc. was founded in 1982. Initially focused on antibodies for diagnostics, it evolved to concentrate on developing immunotherapies for cancer. The company has experienced pipeline setbacks and strategic shifts, including a pivot to focus on receptor tyrosine kinases.

business area logo Core Business Areas

  • Antibody-Based Therapeutics: Develops monoclonal antibodies designed to modulate the immune system to fight cancer.
  • Proprietary Technologies: Utilizes platforms such as its antibody-drug conjugate (ADC) technology and bispecific antibody programs.
  • Clinical Development Programs: Focuses on advancing various clinical-stage drug candidates targeting specific cancers.

leadership logo Leadership and Structure

Anthony Marucci is the President and CEO. The organizational structure includes research, clinical development, and commercialization teams.

Top Products and Market Share

overview logo Key Offerings

  • Varlilumab: An investigational CD27 agonist antibody being evaluated in clinical trials for various cancers. While it doesn't have market share yet, it is a key pipeline asset. Competitors are checkpoint inhibitors and other immunotherapies developed by companies like Bristol Myers Squibb (BMY) and Merck (MRK).
  • CDX-0159: A monoclonal antibody designed to target KIT and is in clinical development for the treatment of chronic urticaria. While it doesn't have market share yet, it is a key pipeline asset. Competitors are Xolair (Novartis (NVS)) and other drugs used to treat chronic hives.

Market Dynamics

industry overview logo Industry Overview

The biopharmaceutical industry is highly competitive and research-intensive, driven by innovation in drug discovery and development. The market is characterized by high regulatory hurdles and patent protection.

Positioning

Celldex is a biotechnology company specializing in immunotherapies. Its competitive advantage lies in its antibody-based technologies and targeted therapies.

Total Addressable Market (TAM)

The immuno-oncology market is expected to reach hundreds of billions of dollars. Celldex is positioned to capture a portion of this TAM with successful clinical trials and drug approvals.

Upturn SWOT Analysis

Strengths

  • Proprietary antibody technologies
  • Targeted therapy approach
  • Experienced management team
  • Strong research capabilities

Weaknesses

  • Limited commercialized products
  • Dependence on clinical trial outcomes
  • High R&D expenses
  • Susceptible to regulatory risks

Opportunities

  • Expanding immuno-oncology market
  • Partnerships and collaborations
  • Successful clinical trial results
  • New drug approvals

Threats

  • Competition from larger pharmaceutical companies
  • Clinical trial failures
  • Regulatory hurdles
  • Patent expirations

Competitors and Market Share

competitor logo Key Competitors

  • BMY
  • MRK
  • NVS
  • LLY

Competitive Landscape

Celldex faces intense competition from larger pharmaceutical companies with more resources. Its competitive advantage lies in its niche focus and proprietary technologies.

Growth Trajectory and Initiatives

Historical Growth: Growth has been largely dependent on the progression of its clinical pipeline. Fluctuations are typical in this space.

Future Projections: Future growth is heavily dependent on the success of its clinical programs. Analyst estimates vary widely.

Recent Initiatives: Focus on advancing CDX-0159 and Varlilumab through clinical trials and exploring strategic partnerships.

Summary

Celldex Therapeutics is a biotechnology company with potential in its immunotherapy pipeline, particularly CDX-0159. Its success hinges on positive clinical trial outcomes. The company faces significant competition and financial risks common in the biotech industry. Strategic partnerships and successful product development are crucial for its future growth.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company filings
  • Financial news sources
  • Analyst reports

Disclaimers:

The information provided is for informational purposes only and should not be considered financial advice. Investment decisions should be based on thorough research and consultation with a financial professional.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Celldex Therapeutics Inc

Exchange NASDAQ
Headquaters Hampton, NJ, United States
IPO Launch date 2008-03-10
Founder, President, CEO & Director Mr. Anthony S. Marucci M.B.A.
Sector Healthcare
Industry Biotechnology
Full time employees 186
Full time employees 186

Celldex Therapeutics, Inc., a biopharmaceutical company, engages in developing therapeutic antibodies for patients with severe inflammatory, allergic, autoimmune, and other diseases. The company's drug candidates include monoclonal and bispecific antibodies designed to address mast cell mediated diseases for which available treatments are inadequate. Its clinical development programs are Barzolvolimab (CDX-0159), a monoclonal antibody that specifically binds the KIT receptor and potently inhibits its activity for treating chronic urticarias, prurigo nodularis, eosinophilic esophagitis, and atopic dermatitis; and CDX-622, a bispecific candidate for inflammatory diseases, which targets two complementary pathways that drive chronic inflammation, potently neutralizing the alarmin thymic stromal lymphopoietin and depleting mast cells through stem cell factor starvation. The company is headquartered in Hampton, New Jersey.