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Upturn AI Summary - About
Celldex Therapeutics Inc(CLDX)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Stock price based on last close Advisory Performance History (Simulated)
Upturn Advisory & Investor View for CLDX
10/22/2026: CLDX (1-star) is currently NOT-A-BUY. Pass it for now.
Celldex Therapeutics is a clinical-stage biotechnology company focused on developing monoclonal and bispecific antibody therapeutics for inflammatory and fibrotic diseases. Its primary value driver is Barzolvolimab, a lead antibody candidate showing promise in chronic urticaria trials. The company's main strength lies in its specialized technology platform and a focused, well-managed pipeline. However, it faces significant risks including high cash burn, a lack of commercialized products, and intense competition from large pharmaceutical incumbents. The company is best suited for growth-oriented investors who can tolerate high clinical trial-related volatility and are monitoring for positive Phase 3 data and regulatory milestones as key indicators of long-term success.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Mixed fit | The company offers potential high growth tied to clinical trial success but lacks current revenue-generating commercial products. |
| Momentum investor | Strong fit while signal remains positive | The stock often reacts sharply to clinical data releases, providing opportunities for short-term price appreciation. |
| Value investor | Weak fit | Valuation is difficult to ascertain given the lack of earnings and reliance on speculative clinical outcomes. |
| Dividend investor | Weak fit | The company does not pay dividends and is in a capital-intensive growth phase. |
| Low-risk investor | Weak fit | The high volatility and clinical risk profile make this unsuitable for risk-averse investors. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | The stock is highly sensitive to binary clinical events and biotechnology market sentiment. |
| Valuation risk | High | Determining fair value is complex without commercial revenue or positive cash flow. |
| Competition risk (Immunology) | Medium / high | Large pharmaceutical competitors have greater resources to develop and market alternative treatments. |
| Business quality | Medium | The company demonstrates strong technical expertise in antibodies, though lacks a track record of commercialized products. |
| Dividend income | Low / none | There is no income component to the investment. |
| Execution risk | High | Successful clinical trial execution and FDA approval are critical to the company's survival. |
Price Behavior
Rolling Over
The price momentum is slowing down and beginning to turn downward.
Choppy
The stock has experienced frequent reversals and pronounced short-term price swings.
Analysis of Past Performance
Type Stock | Historic Profit -49.22% | Avg. Invested days 28 | Today’s Advisory PASS |
Upturn Advisory Rating  | Upturn Advisory Performance  2.0 | Stock Returns Performance  1.0 |
| Profits based on simulation | Last Close 10/22/2026 |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals
Financial Health Rating
Growth Momentum Score
Ownership
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue)
Economic Dimensions
Quantitative Style Profile
Style Classification
Quality Focused
Key Highlights
Company Size Mid-Cap Stock | Market Capitalization 2.31B USD | Price to earnings Ratio - | 1Y Target Price 63.07 |
Price to earnings Ratio - | 1Y Target Price 63.07 | ||
Volume (30-day avg) 2.0M shares | Beta 0.9 | 52 Weeks Range 22.10 - 45.14 | Updated Date 10/21/2026 |
52 Weeks Range 22.10 - 45.14 | Updated Date 10/21/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -4.22 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Drug Development | Clinical-stage R&D for antibody therapeutics like Barzolvolimab. | The company is betting on the clinical success of its lead drug to eventually generate revenue. |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Valuation
Trailing PE - | Forward PE - | Enterprise Value 1.73B | Price to Sales(TTM) 14597.55 |
Enterprise Value 1.73B | Price to Sales(TTM) 14597.55 | ||
Enterprise Value to Revenue 12149.54 | Enterprise Value to EBITDA -17.34 | Shares Outstanding 78.53M | Shares Floating 73.02M |
Shares Outstanding 78.53M | Shares Floating 73.02M | ||
Percent Insiders 0.27 | Percent Institutions 109.93 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
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