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CLSD logo CLSD
Upturn stock ratingUpturn stock rating
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Clearside Biomedical Inc (CLSD)

Upturn stock ratingUpturn stock rating
$0.8
Last Close (24-hour delay)
upturn advisory
PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK

Upturn Advisory Summary

06/30/2025: CLSD (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

7 Analysts rated it

Moderately tracked stock, growing coverage, gaining market and investor attention.

1 Year Target Price $5.43

1 Year Target Price $5.43

Analysts Price Target For last 52 week
$5.43Target price
Low$0.7
Current$0.8
high$1.65

Analysis of Past Performance

Type Stock
Historic Profit -45.06%
Avg. Invested days 21
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 1.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 06/30/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 59.84M USD
Price to earnings Ratio -
1Y Target Price 5.43
Price to earnings Ratio -
1Y Target Price 5.43
Volume (30-day avg) 7
Beta 2.06
52 Weeks Range 0.70 - 1.65
Updated Date 06/30/2025
52 Weeks Range 0.70 - 1.65
Updated Date 06/30/2025
Dividends yield (FY) -
Basic EPS (TTM) -0.41

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -223.39%

Management Effectiveness

Return on Assets (TTM) -54.08%
Return on Equity (TTM) -1310.02%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 48380743
Price to Sales(TTM) 15.9
Enterprise Value 48380743
Price to Sales(TTM) 15.9
Enterprise Value to Revenue 12.85
Enterprise Value to EBITDA -2.84
Shares Outstanding 77708496
Shares Floating 67402053
Shares Outstanding 77708496
Shares Floating 67402053
Percent Insiders 13.02
Percent Institutions 14.32

Analyst Ratings

Rating 3
Target Price 5.43
Buy 3
Strong Buy 4
Buy 3
Strong Buy 4
Hold -
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Clearside Biomedical Inc

stock logo

Company Overview

overview logo History and Background

Clearside Biomedical, Inc. is a biopharmaceutical company focused on the research, development, and commercialization of therapies for eye diseases. Founded in 2011, it is known for its suprachoroidal space (SCS) injection platform.

business area logo Core Business Areas

  • Ophthalmology: Develops and commercializes therapies using its proprietary SCS injection platform to treat various eye diseases.

leadership logo Leadership and Structure

George Lasezkay, MD, is the CEO. The company has a board of directors and operates with typical functional departments like R&D, manufacturing, commercial, etc.

Top Products and Market Share

overview logo Key Offerings

  • XIPERE: XIPERE (triamcinolone acetonide injectable suspension) is Clearside's primary commercial product, approved for the treatment of macular edema associated with uveitis. Market share data is difficult to ascertain precisely due to varied causes of uveitis. Competitors include steroid treatments and other therapies addressing uveitis-related macular edema. Competitors include AbbVie (Humira), Regeneron (Eylea).

Market Dynamics

industry overview logo Industry Overview

The ophthalmology market is large and growing, driven by aging populations and increased prevalence of eye diseases. Novel drug delivery methods are gaining traction.

Positioning

Clearside's SCS injection platform provides a differentiated approach to drug delivery in the eye, potentially offering improved efficacy and reduced side effects. The company is well-positioned within the niche of uveitis-related macular edema.

Total Addressable Market (TAM)

The global uveitis market is estimated to be in billions of USD. Clearside is targeting a specific subsegment with XIPERE. Market is constantly expanding as the elderly populations are increasing.

Upturn SWOT Analysis

Strengths

  • Proprietary SCS injection platform
  • FDA-approved product (XIPERE)
  • Experienced management team
  • Specific focus on niche market

Weaknesses

  • Limited product portfolio
  • Reliance on a single product for revenue
  • Small market capitalization
  • Requires specialist for injection

Opportunities

  • Expanding indications for SCS injection platform
  • Partnerships and collaborations
  • Geographic expansion
  • Development of new ophthalmology therapies

Threats

  • Competition from established pharmaceutical companies
  • Regulatory hurdles
  • Patent expirations
  • Clinical trial failures

Competitors and Market Share

competitor logo Key Competitors

  • ABBV
  • REGN
  • SNY

Competitive Landscape

Clearside has a unique drug delivery system but faces intense competition from established players with broader product portfolios and greater resources. XIPERE is only treatment for uveitis related macular edema, however AbbVie and Regeneron treat a wider range of eye problems with more effective treatments.

Growth Trajectory and Initiatives

Historical Growth: Historical growth has been tied to the development and commercialization of XIPERE.

Future Projections: Future growth will depend on the continued sales growth of XIPERE, expansion into new indications, and potential partnerships.

Recent Initiatives: Recent initiatives include expanding commercialization efforts for XIPERE and advancing other pipeline candidates.

Summary

Clearside Biomedical is a biopharmaceutical company focused on ophthalmology, centered around its suprachoroidal space injection platform. The company's success depends heavily on the sales of its sole commercial product, XIPERE, and its ability to expand into new indications. It faces strong competition from larger pharmaceutical companies. Clearside needs to diversify its product portfolio and secure strategic partnerships to ensure long-term growth. It is also challenged by the specific injection for the drug and other competitors that can treat a wider variety of eye problems.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • SEC Filings (10-K, 10-Q)
  • Company Website
  • Analyst Reports
  • Press Releases

Disclaimers:

This analysis is for informational purposes only and should not be considered investment advice. Market share data is estimates and may vary. Consult with a qualified financial advisor before making any investment decisions.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Clearside Biomedical Inc

Exchange NASDAQ
Headquaters Alpharetta, GA, United States
IPO Launch date 2016-06-02
President, CEO & Director Dr. George M. Lasezkay J.D., Pharm.D., Pharma.D.
Sector Healthcare
Industry Biotechnology
Full time employees 32
Full time employees 32

Clearside Biomedical, Inc., a biopharmaceutical company, focuses on the revolutionizing the delivery of therapies to the back of the eye through the suprachoroidal space. The company offers XIPERE, a triamcinolone acetonide injectable suspension for the treatment of macular edema associated with uveitis. It also develops CLS-AX, an axitinib injectable suspension for suprachoroidal injection, which has completed Phase 2 clinical trial to treat wet AMD. The company has a collaboration with bausch + lomb ireland limited, Arctic Vision (Hong Kong) Limited, REGENXBIO, Inc., BioCryst Pharmaceuticals, Inc., and Aura Biosciences, Inc. Clearside Biomedical, Inc. was incorporated in 2011 and is headquartered in Alpharetta, Georgia.