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Upturn AI Summary - About
Cardiff Oncology Inc(CRDF)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Stock price based on last close Advisory Performance History (Simulated)
Upturn Advisory & Investor View for CRDF
10/23/2026: CRDF (1-star) is currently NOT-A-BUY. Pass it for now.
Cardiff Oncology is a clinical-stage biotechnology company developing onvansertib, a proprietary PLK1 inhibitor intended to overcome treatment resistance in difficult-to-treat solid tumors. The company's main strength lies in its specialized focus on targeting metastatic colorectal and pancreatic cancers, aiming to enhance standard chemotherapy efficacy. The primary investment story rests on successful clinical trial readouts that could validate its drug candidate for partnership or acquisition. However, Cardiff faces substantial risks, including a lack of commercial revenue, consistent cash burn, and intense competition from much larger pharmaceutical firms. The stock is best suited for speculative investors comfortable with high volatility and potential clinical setbacks.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Mixed fit | The company offers potential for high growth if clinical trials succeed, but execution risk is very high. |
| Momentum investor | Strong fit while signal remains positive | Biotech stocks often experience rapid price movement surrounding positive clinical data or partnership announcements. |
| Value investor | Weak fit | Lack of earnings, revenue, and assets makes traditional value metrics inapplicable. |
| Dividend investor | Weak fit | The company does not pay dividends and reinvests all capital into research. |
| Low-risk investor | Weak fit | High clinical and financial risk makes this unsuitable for conservative portfolios. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | Clinical-stage biotechs are prone to sharp price swings based on data readouts. |
| Valuation risk | High | Valuation is speculative and dependent on future success probabilities of drug candidates. |
| Competition risk (targeted oncology) | High | Large incumbents with massive R&D budgets compete directly for efficacy in solid tumors. |
| Business quality | Medium | The company is early-stage with no commercial products or established cash flow. |
| Dividend income | Low / none | No capital is returned to shareholders; cash is strictly for operations. |
| Execution risk | High | Clinical success is uncertain, and failing to meet trial endpoints can collapse equity value. |
Price Behavior
Steep Decline
The stock price has dropped sharply with strong downward pressure.
Extreme Price Shocks
The stock has experienced exceptionally large and disruptive price movements during the period.
Analysis of Past Performance
Type Stock | Historic Profit 21.91% | Avg. Invested days 25 | Today’s Advisory PASS |
Upturn Advisory Rating  | Upturn Advisory Performance  2.0 | Stock Returns Performance  3.0 |
| Profits based on simulation | Last Close 10/23/2026 |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals
Financial Health Rating
Growth Momentum Score
Ownership
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue)
Economic Dimensions
Quantitative Style Profile
Style Classification
Quality Focused
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 72.19M USD | Price to earnings Ratio - | 1Y Target Price 5.81 |
Price to earnings Ratio - | 1Y Target Price 5.81 | ||
Volume (30-day avg) 673.8K shares | Beta 1.42 | 52 Weeks Range 0.76 - 3.31 | Updated Date 10/23/2026 |
52 Weeks Range 0.76 - 3.31 | Updated Date 10/23/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.59 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Oncology Therapeutics | Research, development, and eventual licensing or commercialization of the drug candidate onvansertib. | The company currently spends money rather than earning it, relying on equity raises to fund development in hopes of a future drug approval. |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Valuation
Trailing PE - | Forward PE - | Enterprise Value 69.40M | Price to Sales(TTM) 142.11 |
Enterprise Value 69.40M | Price to Sales(TTM) 142.11 | ||
Enterprise Value to Revenue 136.62 | Enterprise Value to EBITDA -3.66 | Shares Outstanding 77.80M | Shares Floating 75.38M |
Shares Outstanding 77.80M | Shares Floating 75.38M | ||
Percent Insiders 6.2 | Percent Institutions 22.07 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
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