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Dermata Therapeutics Inc (DRMA)



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Upturn Advisory Summary
08/28/2025: DRMA (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $10
1 Year Target Price $10
0 | Strong Buy |
1 | Buy |
0 | Hold |
0 | Sell |
0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -30.96% | Avg. Invested days 6 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 3.65M USD | Price to earnings Ratio 0.26 | 1Y Target Price 10 |
Price to earnings Ratio 0.26 | 1Y Target Price 10 | ||
Volume (30-day avg) 1 | Beta 0.56 | 52 Weeks Range 5.09 - 24.90 | Updated Date 08/29/2025 |
52 Weeks Range 5.09 - 24.90 | Updated Date 08/29/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) 20.96 |
Earnings Date
Report Date 2025-08-13 | When - | Estimate -0.44 | Actual -1.66 |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -110.91% | Return on Equity (TTM) -231.27% |
Valuation
Trailing PE 0.26 | Forward PE - | Enterprise Value -2834601 | Price to Sales(TTM) - |
Enterprise Value -2834601 | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA 0.58 | Shares Outstanding 681557 | Shares Floating 498470 |
Shares Outstanding 681557 | Shares Floating 498470 | ||
Percent Insiders 17 | Percent Institutions 7.46 |
Upturn AI SWOT
Dermata Therapeutics Inc

Company Overview
History and Background
Dermata Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing and commercializing innovative, differentiated, and safe dermatology products. Founded in 2014, they are developing treatments for common skin conditions like acne, rosacea, and psoriasis. They are focused on novel approaches using reactive oxidative species (ROS) to modulate inflammation and sebum production.
Core Business Areas
- Dermatology Therapeutics Development: Focuses on the research, development, and eventual commercialization of prescription dermatology products.
- Reactive Oxidative Species (ROS) Platform: The company's core technology revolves around utilizing ROS to treat skin conditions.
Leadership and Structure
The leadership team consists of experienced executives in the pharmaceutical and biotechnology industries. The organizational structure is typical of a clinical-stage biotech, with departments dedicated to research and development, clinical trials, regulatory affairs, and business development.
Top Products and Market Share
Key Offerings
- DMT310: A topical treatment being developed for acne, rosacea and psoriasis, targeting sebum production and inflammation. Currently in clinical trials. Limited market share data available as the product is not yet commercialized. Competitors include companies offering topical and oral treatments for acne (e.g., Galderma, Bausch Health), rosacea (e.g., Galderma, Allergan), and psoriasis (e.g., AbbVie, Amgen).
- DMT410: A topical treatment being developed for the treatment of acne, rosacea and psoriasis. Currently in pre-clinical development. Limited market share data available as the product is not yet commercialized.
Market Dynamics
Industry Overview
The dermatology market is large and growing, driven by increasing prevalence of skin conditions, aging populations, and demand for aesthetic treatments. It includes prescription and over-the-counter products for a wide range of conditions.
Positioning
Dermata is positioned as an innovative company developing differentiated dermatology products based on its ROS technology platform. Their competitive advantage relies on the potential efficacy and safety profiles of their novel treatments.
Total Addressable Market (TAM)
The TAM for acne, rosacea, and psoriasis treatments is estimated to be in the billions of dollars globally. Dermata is positioned to capture a portion of this market with successful clinical trials and commercialization of their products. For example, the global acne treatment market is expected to reach $13.5 billion by 2030.
Upturn SWOT Analysis
Strengths
- Novel ROS technology platform
- Targeting large dermatology markets
- Experienced management team
- Focus on unmet needs in dermatology
Weaknesses
- Limited financial resources
- Reliance on successful clinical trials
- No currently marketed products
- High risk of clinical trial failure
Opportunities
- Potential for partnerships and licensing agreements
- Expansion into new dermatology indications
- Positive clinical trial results
- Increasing awareness of skin conditions
Threats
- Competition from established pharmaceutical companies
- Regulatory hurdles
- Clinical trial failures
- Generic competition
Competitors and Market Share
Key Competitors
- ABBV
- LLY
- BMY
- GILD
- MRK
- PFE
Competitive Landscape
Dermata faces intense competition from large pharmaceutical companies with established dermatology portfolios. Their advantage lies in their novel technology platform, but they need to demonstrate superior efficacy and safety in clinical trials.
Growth Trajectory and Initiatives
Historical Growth: Historical growth is limited as the company has not yet commercialized any products.
Future Projections: Future growth is dependent on the successful development and commercialization of their product candidates. Analyst estimates vary widely due to the inherent risks associated with clinical-stage biotechnology companies.
Recent Initiatives: Focusing on advancing DMT310 through clinical trials, exploring potential partnerships, and managing cash resources.
Summary
Dermata Therapeutics is a high-risk, high-reward clinical-stage company with a novel technology platform targeting large dermatology markets. Their success depends on positive clinical trial results and successful commercialization. The company needs to manage its cash resources carefully and navigate a competitive landscape dominated by larger pharmaceutical companies. The main risk for Dermata is clinical trial failures.
Peer Comparison
Sources and Disclaimers
Data Sources:
- Company Website
- SEC Filings
- Analyst Reports
- Market Research Reports
Disclaimers:
This analysis is for informational purposes only and does not constitute investment advice. The information provided is based on available data and is subject to change. Investing in clinical-stage biotechnology companies involves significant risks.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Dermata Therapeutics Inc
Exchange NASDAQ | Headquaters San Diego, CA, United States | ||
IPO Launch date 2021-08-13 | Founder, President, CEO & Chairman Mr. Gerald T. Proehl | ||
Sector Healthcare | Industry Biotechnology | Full time employees 8 | Website https://www.dermatarx.com |
Full time employees 8 | Website https://www.dermatarx.com |
Dermata Therapeutics, Inc., a late-stage medical dermatology company, focuses on identifying, developing, and commercializing pharmaceutical product candidates for the treatment of medical skin diseases and aesthetic applications. Its lead product candidate is XYNGARI, which is in Phase 3 clinical studies for the treatment of moderate-to-severe acne, as well as completed Phase 1b proof of concept (POC) trial for mild-to-moderate psoriasis. The company is also developing DMT410 that has completed Phase 1b POC trials for the treatment of axillary hyperhidrosis and aesthetic skin conditions. It has a clinical trial collaboration agreement with Revance Therapeutics, Inc. to conduct a multi-center clinical trial to evaluate the topical application of XYNGARI with DAXXIFY, Revance's botulinum toxin type A. Dermata Therapeutics, Inc. was incorporated in 2014 and is headquartered in San Diego, California.

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