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Durect Corporation (DRRX)

Upturn stock ratingUpturn stock rating
$1.91
Last Close (24-hour delay)
Profit since last BUY0%
upturn advisory
Consider higher Upturn Star rating
BUY since 30 days
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Upturn Advisory Summary

09/10/2025: DRRX (1-star) has a low Upturn Star Rating. Not recommended to BUY.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

3 Analysts rated it

Very few follow this stock; limited insights, higher-risk early investing.

1 Year Target Price $2.5

1 Year Target Price $2.5

Analysts Price Target For last 52 week
$2.5 Target price
52w Low $0.48
Current$1.91
52w High $2.64

Analysis of Past Performance

Type Stock
Historic Profit -25.96%
Avg. Invested days 24
Today’s Advisory Consider higher Upturn Star rating
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 3.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 09/10/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 59.31M USD
Price to earnings Ratio -
1Y Target Price 2.5
Price to earnings Ratio -
1Y Target Price 2.5
Volume (30-day avg) 3
Beta 0.93
52 Weeks Range 0.48 - 2.64
Updated Date 09/14/2025
52 Weeks Range 0.48 - 2.64
Updated Date 09/14/2025
Dividends yield (FY) -
Basic EPS (TTM) -0.43

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Revenue by Geography

Geography revenue - Year on Year

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -209.9%
Operating Margin (TTM) -627.07%

Management Effectiveness

Return on Assets (TTM) -45.34%
Return on Equity (TTM) -307.39%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 54561497
Price to Sales(TTM) 35.8
Enterprise Value 54561497
Price to Sales(TTM) 35.8
Enterprise Value to Revenue 32.93
Enterprise Value to EBITDA -2.48
Shares Outstanding 31054200
Shares Floating 26469657
Shares Outstanding 31054200
Shares Floating 26469657
Percent Insiders 12.67
Percent Institutions 23.57

ai summary icon Upturn AI SWOT

Durect Corporation

stock logo

Company Overview

overview logo History and Background

Durect Corporation was founded in 1998. The company focuses on developing novel and proprietary therapeutics for chronic diseases and acute conditions.

business area logo Core Business Areas

  • Drug Delivery Technologies: Durect develops and manufactures sustained-release drug delivery systems.
  • Pharmaceutical Development: The company develops its own proprietary pharmaceutical products, often leveraging its drug delivery technologies.

leadership logo Leadership and Structure

James E. Brown is the President and CEO. The company operates with a functional organizational structure.

Top Products and Market Share

overview logo Key Offerings

  • ALZET Osmotic Pumps: These are small, implantable pumps used for continuous drug delivery in research. Revenue generated from this product is confidential and the exact market share is unknown. Competitors include Smiths Medical and Medtronic (MDT).
  • POSIMIR: A post-operative pain relief depot indicated for direct administration into the surgical site to manage post-surgical pain for up to 72 hours. This product is licensed. Competitors are generic pain medications, and alternatives like opioids and NSAIDs.
  • ORADUR technology: An oral drug delivery system. Revenue generated from this product is confidential and the exact market share is unknown.

Market Dynamics

industry overview logo Industry Overview

The pharmaceutical industry is highly competitive and regulated, characterized by continuous innovation and development of new therapies.

Positioning

Durect is positioned as a specialty pharmaceutical company focused on drug delivery technologies and niche therapeutics.

Total Addressable Market (TAM)

The TAM for controlled-release drug delivery systems is substantial. Exact TAM is difficult to define because it depends upon the specific therapeutic areas and product targets. Durect occupies a small segment of the drug delivery space.

Upturn SWOT Analysis

Strengths

  • Proprietary drug delivery technologies
  • Established partnerships
  • Experienced management team

Weaknesses

  • Limited product pipeline
  • Dependence on partners for revenue
  • History of net losses

Opportunities

  • Expansion into new therapeutic areas
  • Development of new drug delivery platforms
  • Increased demand for sustained-release medications

Threats

  • Competition from larger pharmaceutical companies
  • Regulatory hurdles
  • Patent expiration

Competitors and Market Share

competitor logo Key Competitors

  • PACB
  • XOMA
  • VTVT

Competitive Landscape

Durect faces competition from larger pharmaceutical companies with more resources. Their competitive advantage lies in their specialized drug delivery technologies and the development of niche products.

Growth Trajectory and Initiatives

Historical Growth: Historical growth has been sporadic, dependent on licensing agreements and product development progress.

Future Projections: Future growth relies on clinical trial outcomes, partnerships, and regulatory approvals for their products

Recent Initiatives: Focus on their activities with their existing products such as POSIMIR and ALZET and their drug delivery technologies like ORADUR

Summary

Durect Corporation specializes in drug delivery technologies and has potential for growth. Its strategic partnerships are a plus, but the company has experienced net losses in the past, faces stiff competition, and depends greatly on third-party success. Further success hinges on successful clinical trials, regulatory approvals, and expanding its product pipeline. Durect needs to focus on profitability and reducing its dependence on external partners.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Durect Corporation Investor Relations
  • SEC Filings
  • Various Financial News Outlets

Disclaimers:

The information provided is for informational purposes only and should not be considered financial advice. Market share data is estimated and may not be precise. Financial data should be verified with official company documents.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Durect Corporation

Exchange NASDAQ
Headquaters Cupertino, CA, United States
IPO Launch date 2000-09-28
Co-Founder, CEO, President & Director Dr. James E. Brown D.V.M.
Sector Healthcare
Industry Drug Manufacturers - Specialty & Generic
Full time employees 13
Full time employees 13

DURECT Corporation, a biopharmaceutical company, develops medicines based on its epigenetic regulator program. The company's lead product candidate includes larsucosterol, an endogenous, orally bioavailable small molecule to play a regulatory role in lipid metabolism, stress and inflammatory responses, and cell death and survival to treat alcohol-associated hepatitis, as well as for the treatment of patients with metabolic dysfunction-associated steatohepatitis. The company also offers POSIMIR, a post-surgical pain product to deliver bupivacaine over three days in adults; PERSERIS, an injectable suspension for the treatment of schizophrenia in adults; and Methydur to treat attention deficit hyperactivity disorder. It has strategic collaboration and other agreements with Virginia Commonwealth University Intellectual Property Foundation and Innocoll Pharmaceuticals Limited. DURECT Corporation was incorporated in 1998 and is headquartered in Cupertino, California. As of September 11, 2025, DURECT Corporation operates as a subsidiary of Bausch Health Americas, Inc.