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Dyadic International Inc (DYAI)



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Upturn Advisory Summary
08/28/2025: DYAI (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $9
1 Year Target Price $9
0 | Strong Buy |
1 | Buy |
0 | Hold |
0 | Sell |
0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -51.95% | Avg. Invested days 23 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 33.69M USD | Price to earnings Ratio - | 1Y Target Price 9 |
Price to earnings Ratio - | 1Y Target Price 9 | ||
Volume (30-day avg) 1 | Beta 0.89 | 52 Weeks Range 0.71 - 2.20 | Updated Date 08/28/2025 |
52 Weeks Range 0.71 - 2.20 | Updated Date 08/28/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.19 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Earnings Date
Report Date 2025-08-13 | When - | Estimate -0.06 | Actual -0.06 |
Profitability
Profit Margin -134.84% | Operating Margin (TTM) -177.21% |
Management Effectiveness
Return on Assets (TTM) -36.14% | Return on Equity (TTM) -422.64% |
Valuation
Trailing PE - | Forward PE 15.82 | Enterprise Value 32917261 | Price to Sales(TTM) 8.15 |
Enterprise Value 32917261 | Price to Sales(TTM) 8.15 | ||
Enterprise Value to Revenue 9.62 | Enterprise Value to EBITDA -2.93 | Shares Outstanding 36187800 | Shares Floating 26907437 |
Shares Outstanding 36187800 | Shares Floating 26907437 | ||
Percent Insiders 25.17 | Percent Institutions 13.88 |
Upturn AI SWOT
Dyadic International Inc

Company Overview
History and Background
Dyadic International Inc. was founded in 1979. Originally focused on citrus processing, Dyadic evolved into a biotechnology company focused on enzyme development and biomanufacturing using its patented C1 technology.
Core Business Areas
- C1 Technology Platform: Dyadic's core business revolves around its C1 technology platform, a fungal expression system used for the production of enzymes and other proteins.
- Licensing and Collaboration: Dyadic generates revenue through licensing its C1 technology to companies in various industries and collaborating on development projects.
- Enzyme Development and Manufacturing: Dyadic develops and manufactures enzymes for a range of applications, including animal health, human health, and industrial uses.
Leadership and Structure
Dyadic International Inc. is led by a board of directors and an executive management team. The company structure includes research and development, manufacturing, sales and marketing, and administrative functions.
Top Products and Market Share
Key Offerings
- C1 Expression System: Dyadic's proprietary C1 expression system enables the production of a variety of proteins. Market share data is difficult to ascertain precisely, given the varying applications, but it is used by companies such as Phibro Animal Health. Competitors include Thermo Fisher Scientific (TMO) with their cell-based systems and microbial fermentation companies.
- Enzymes for Animal Health: Enzymes designed for animal feed and health applications. Market share data is difficult to pinpoint due to the fragmented nature of the animal feed enzymes market, competition includes DSM (DSM.AS) and Novozymes (NVZMY).
Market Dynamics
Industry Overview
The biotechnology industry is characterized by rapid innovation, high regulatory hurdles, and significant investment in research and development. Demand for biomanufacturing platforms and enzymes continues to grow in the pharmaceutical, food and beverage, and animal health sectors.
Positioning
Dyadic is positioned as a technology provider with a unique fungal expression platform. The company aims to offer a cost-effective and efficient alternative to traditional expression systems.
Total Addressable Market (TAM)
The global market for biopharmaceutical manufacturing is estimated at hundreds of billions USD and growing. The animal feed enzyme market is valued at several billion USD annually. Dyadic is positioned to capture a small but growing share of these markets through its C1 technology.
Upturn SWOT Analysis
Strengths
- Proprietary C1 technology platform
- Potential for high protein expression yields
- Cost-effective production capabilities
- Established partnerships with industry players
Weaknesses
- Limited revenue streams
- Dependence on partnerships and licensing agreements
- Relatively small size compared to industry giants
- Past history of financial losses
Opportunities
- Expanding applications of C1 technology in new markets
- Growing demand for biomanufacturing solutions
- Potential for strategic acquisitions or partnerships
- Development of new and improved enzyme products
Threats
- Competition from established biotechnology companies
- Regulatory hurdles and approval processes
- Technological advancements that render C1 obsolete
- Economic downturn impacting R&D spending
Competitors and Market Share
Key Competitors
- TMO
- NVZMY
- DSM.AS
Competitive Landscape
Dyadic's C1 platform offers a unique alternative to cell-based expression systems. However, the company faces competition from larger, more established players with broader product portfolios and greater resources.
Growth Trajectory and Initiatives
Historical Growth: Dyadic's historical growth has been uneven, driven by milestones in partnerships and licensing agreements.
Future Projections: Future growth projections are based on the success of ongoing development programs and the signing of new partnerships.
Recent Initiatives: Recent initiatives include expanding C1 technology applications to new areas such as human health and biopharmaceuticals.
Summary
Dyadic International Inc. is a biotechnology company with a unique C1 technology platform. While the C1 platform has potential, the company faces risks associated with a small size, revenue dependence on partnerships, and competition from established companies. Future growth depends on successful development programs. Further evaluation of recent financial statements is crucial for investment.
Peer Comparison
Sources and Disclaimers
Data Sources:
- Company Website
- SEC Filings
- Analyst Reports
Disclaimers:
This analysis is for informational purposes only and does not constitute financial advice. Investment decisions should be based on thorough research and consultation with a qualified financial advisor.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Dyadic International Inc
Exchange NASDAQ | Headquaters Jupiter, FL, United States | ||
IPO Launch date 2004-11-05 | Founder, CEO & Director Mr. Mark A. Emalfarb | ||
Sector Healthcare | Industry Biotechnology | Full time employees 6 | Website https://www.dyadic.com |
Full time employees 6 | Website https://www.dyadic.com |
Dyadic International, Inc., a biotechnology platform company, develops, produces, and sells industrial enzymes and other proteins in the United States and internationally. It utilizes the C1 platform in pharmaceutical applications, including the development and production of pharmaceutical products. The company offers Dapibus, a protein production platform that enable the rapid development and large-scale manufacture of cost-effective enzymes, proteins, metabolites, and other biologic products for life sciences, food and nutrition, and bioindustrial applications. In addition, it develops DYAI-100, a C1-SARS-CoV-2 recombinant protein RBD vaccine candidate and first C1, which is in phase 1 clinical trial to produce protein tested in humans. The company has a research and development agreement with VTT Technical Research Centre of Finland, Ltd.; license agreement with South Africa's Rubic One Health; joint development agreement with a Global Food Ingredient Company; and sub-license agreement with Abic Biological Laboratories Ltd., Alphazyme, LLC, and Abic Biological Laboratories Ltd. Dyadic International, Inc. was founded in 1979 and is headquartered in Jupiter, Florida.

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