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Dyadic International Inc (DYAI)



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Upturn Advisory Summary
06/27/2025: DYAI (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $9
1 Year Target Price $9
0 | Strong Buy |
1 | Buy |
0 | Hold |
0 | Sell |
0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -36.68% | Avg. Invested days 25 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 29.79M USD | Price to earnings Ratio - | 1Y Target Price 9 |
Price to earnings Ratio - | 1Y Target Price 9 | ||
Volume (30-day avg) 1 | Beta 0.9 | 52 Weeks Range 0.91 - 2.20 | Updated Date 07/1/2025 |
52 Weeks Range 0.91 - 2.20 | Updated Date 07/1/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.2 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin -163.94% | Operating Margin (TTM) -507% |
Management Effectiveness
Return on Assets (TTM) -34.95% | Return on Equity (TTM) -214.26% |
Valuation
Trailing PE - | Forward PE 15.82 | Enterprise Value 27505343 | Price to Sales(TTM) 8.38 |
Enterprise Value 27505343 | Price to Sales(TTM) 8.38 | ||
Enterprise Value to Revenue 8.23 | Enterprise Value to EBITDA -2.93 | Shares Outstanding 30090700 | Shares Floating 19269157 |
Shares Outstanding 30090700 | Shares Floating 19269157 | ||
Percent Insiders 30.19 | Percent Institutions 16.81 |
Analyst Ratings
Rating 1 | Target Price 9 | Buy 1 | Strong Buy - |
Buy 1 | Strong Buy - | ||
Hold - | Sell - | Strong Sell - | |
Strong Sell - |
Upturn AI SWOT
Dyadic International Inc

Company Overview
History and Background
Dyadic International Inc. was founded in 1979. Initially focused on textile enzyme production, it shifted its focus to biotechnology and the development of C1 technology, a fungal expression platform.
Core Business Areas
- C1 Technology Platform: Development and licensing of the C1 fungal expression platform for the production of proteins and metabolites used in various industries, including biopharmaceuticals, animal health, and human health.
Leadership and Structure
Mark Emalfarb serves as the Chief Executive Officer and Director. The company has a board of directors and operates with functional departments covering research and development, licensing, and administration.
Top Products and Market Share
Key Offerings
- C1 Expression Platform: The core offering is the C1 technology platform, a fungal expression system used for producing a wide variety of proteins and metabolites. Dyadic generates revenue through licensing agreements and milestone payments related to its C1 platform. Competitors include traditional expression systems like E. coli, yeast, and mammalian cell culture, offered by companies such as Thermo Fisher Scientific (TMO) and Merck KGaA (MRK.DE).
Market Dynamics
Industry Overview
The biopharmaceutical and industrial biotechnology industries are experiencing significant growth, driven by increasing demand for biologics, biofuels, and other bio-based products. Expression systems are a critical component of these industries.
Positioning
Dyadic positions itself as a provider of a cost-effective and efficient protein expression platform. Its C1 technology aims to offer advantages in terms of speed, yield, and scalability compared to traditional expression systems.
Total Addressable Market (TAM)
The total addressable market for protein expression systems is estimated to be several billion dollars annually. Dyadic aims to capture a portion of this market by licensing its C1 technology. The company's positioning relies on C1's purported efficiency and cost-effectiveness to compete with established systems.
Upturn SWOT Analysis
Strengths
- C1 technology platform with potential for high yield and cost-effective protein production
- Experienced management team
- Partnerships with established companies
- Potential applications across multiple industries
Weaknesses
- Limited financial resources compared to larger competitors
- Reliance on licensing revenue
- Relatively small market presence
- The success of C1 platform depends on acceptance by industry
Opportunities
- Expanding applications of C1 technology in biopharmaceuticals and industrial biotechnology
- Growing demand for cost-effective protein production solutions
- Strategic partnerships and collaborations
- Potential for acquisitions by larger companies
Threats
- Competition from established expression systems
- Technological advancements in alternative protein production methods
- Regulatory hurdles
- Dependence on partners' success in commercializing C1-produced products
Competitors and Market Share
Key Competitors
- TMO
- MRK.DE
Competitive Landscape
Dyadic faces strong competition from established players with larger resources and broader product portfolios. Dyadic aims to compete by offering a potentially more efficient and cost-effective platform.
Major Acquisitions
Alphazyme, LLC
- Year: 2021
- Acquisition Price (USD millions): 5.3
- Strategic Rationale: Acquired Alphazyme to expand enzyme capabilities and accelerate market entry into new industry verticals.
Growth Trajectory and Initiatives
Historical Growth: Dyadic's growth has been driven by licensing agreements and milestone payments. Historical growth has been variable and dependent on the progress of its partners' programs.
Future Projections: Future projections are contingent on the adoption of C1 technology and the success of partnered programs. Analyst estimates vary and can be obtained from financial data providers.
Recent Initiatives: Recent initiatives include expanding partnerships, developing new applications for C1 technology, and pursuing strategic acquisitions.
Summary
Dyadic International shows promise with its C1 technology platform, offering potential advantages in protein production. However, the company's small size and reliance on licensing revenues present challenges. Continued partnership development and successful commercialization of C1-produced products are crucial for future growth, while competition from larger, established players remains a significant hurdle.
Peer Comparison
Sources and Disclaimers
Data Sources:
- Company Website
- SEC Filings
- Financial News Outlets
- Analyst Reports
Disclaimers:
This analysis is for informational purposes only and should not be considered investment advice. The data provided is based on available information and may not be entirely accurate or complete. Investment decisions should be made after consulting with a qualified financial advisor.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Dyadic International Inc
Exchange NASDAQ | Headquaters Jupiter, FL, United States | ||
IPO Launch date 2004-11-05 | Founder, CEO & Director Mr. Mark A. Emalfarb | ||
Sector Healthcare | Industry Biotechnology | Full time employees 6 | Website https://www.dyadic.com |
Full time employees 6 | Website https://www.dyadic.com |
Dyadic International, Inc., a biotechnology platform company, develops, produces, and sells industrial enzymes and other proteins in the United States and internationally. It utilizes the C1 platform in pharmaceutical applications, including the development and production of pharmaceutical products. The company offers Dapibus, a protein production platform that enable the rapid development and large-scale manufacture of cost-effective enzymes, proteins, metabolites, and other biologic products for life sciences, food and nutrition, and bioindustrial applications. In addition, it develops DYAI-100, a C1-SARS-CoV-2 recombinant protein RBD vaccine candidate and first C1, which is in phase 1 clinical trial to produce protein tested in humans. The company has a research and development agreement with VTT Technical Research Centre of Finland, Ltd.; license agreement with South Africa's Rubic One Health; joint development agreement with a Global Food Ingredient Company; and sub-license agreement with Abic Biological Laboratories Ltd., Alphazyme, LLC, and Abic Biological Laboratories Ltd. Dyadic International, Inc. was founded in 1979 and is headquartered in Jupiter, Florida.
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