Enanta Pharmaceuticals Inc logo

Enanta Pharmaceuticals Inc(ENTA)

upturn advisory logo
EXPLORE ADVISORIES AND THEIR HISTORY
QUALITY SIGNAL
1-STAR RATING
PASS
LAST CLOSE
$12.5
10/09/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
  • ALL
  • 1Y
  • 1M
  • 1W
  • BUY Advisory
  • SELL Advisory (Profit)
  • SELL Advisory (Loss)
  • Profit
  • Loss
  • PASS (Skip)
Upturn Stock price based on last close iconStock price based on last close
Simulated performance—not actual client returns. Results depend on calculation assumptions and do not guarantee future outcomes. See Disclosures for methodology, assumptions, and limitations.

Advisory Performance History (Simulated)Advisory Performance History info

Simulated performance—not actual client returns. Results depend on calculation assumptions and do not guarantee future outcomes. See Disclosures for methodology, assumptions, and limitations.

Upturn Advisory & Investor View for ENTA

10/09/2026: ENTA (1-star) is currently NOT-A-BUY. Pass it for now.

Enanta Pharmaceuticals is a clinical-stage biotechnology company that leverages specialized medicinal chemistry to develop treatments for viral and liver diseases. While the company has historically benefited from significant royalty income from Hepatitis C partnerships, its primary investment story now centers on the development of proprietary candidates like EDP-938 for RSV. The company possesses a solid balance sheet and a proven discovery engine, though it faces substantial execution risk as it aims to validate its internal pipeline. Key risks include intense competition from large pharmaceutical incumbents and the binary nature of clinical trial results. The stock is best suited for growth-oriented investors who can tolerate high volatility while monitoring clinical pipeline progress.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorMixed fitEnanta offers potential for significant growth if its pipeline assets receive regulatory approval.
Momentum investorWeak fitThe stock often lacks sustained momentum outside of specific clinical data release windows.
Value investorWeak fitThe company is in a developmental stage, making traditional value metrics difficult to apply.
Dividend investorWeak fitEnanta does not pay a dividend and prioritizes capital reinvestment.
Low-risk investorWeak fitThe high volatility associated with clinical-stage biotech makes this unsuitable for low-risk portfolios.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighClinical results often cause massive, binary stock price movements.
Valuation riskMedium / highValuation is highly speculative and dependent on future success probabilities.
Competition risk (Respiratory and Liver disease market)HighWell-funded incumbents dominate the target therapeutic areas.
Business qualityMediumThe company has a proven discovery engine but lacks a commercial-stage revenue base.
Dividend incomeLow / noneNo income component is provided to shareholders.
Execution riskHighSuccess depends entirely on the clinical and regulatory approval of new assets.

Price Behavior

Downtrend
PRICE PATH

Downtrend

The stock has experienced a sustained decline in price over recent periods.

Moderately Choppy
PRICE STABILITY

Moderately Choppy

The stock has experienced noticeable price swings while retaining some directional structure.

Analysis of Past Performance

Type Stock
Historic Profit -57.09%
Avg. Invested days 26
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 2.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 10/09/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
ENTA receives a 3-star rating, supported by solid analyst coverage. The rating is constrained by weak unit economics, soft quantitative characteristics, and weak price momentum.

Company Fundamentals

★★★★★
ENTA has moderate overall fundamentals (3 stars), with moderate financial health, solid growth momentum, and solid ownership. In FY2025 versus FY2024, solid earnings growth (+29.4%) is partially offset by weak cash generation (FCF margin -49.2%), slightly negative revenue growth (-3.4%), weak profitability (net margin -125.4%).

Financial Health Rating

★★★★★
ENTA's financial health is supported by moderate liquidity, including working-capital and asset support (WC/assets 55.5%). Cash strength is soft (2 stars), which helps explain the 3-star overall score.

Growth Momentum Score

★★★★★
Free-cash-flow growth is ENTA's strongest growth driver at +66.7% FY2025 versus FY2024 (strong, 5 stars). By comparison, earnings growth (+29.4%, solid) is also solid, while revenue growth (-3.4%, slightly negative) holds the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 94.4% and approximately 77.3% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 4.67% provides only moderate management-shareholder alignment.

Top 5 Institutional Investors

HHG PLC 12.99%
Jupiter Topco LLC 12.55%
BlackRock Inc 11.14%
Krensavage Asset Management, LLC 9.84%
Farallon Capital Management, L.L.C. 8.30%

Unit Economics (Per $1K Revenue)

★★★★★
ENTA generates approximately $930 of gross profit, $-1,307 of operating income, and $-492 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Operating losses and cash burn explain the 1-star rating, with weak cash conversion and weak capital efficiency.

Economic Dimensions

★★★★★
Effective Tax Rate: 1.99%

Quantitative Style Profile

★★★★★
ENTA has a liquid profile. Weak momentum is the primary drawback, while soft valuation.

Style Classification

Quality Focused

Small / Mid Cap RiskShort Squeeze RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 352.42M USD
Price to earnings Ratio -
1Y Target Price 21.83
Price to earnings Ratio -
1Y Target Price 21.83
Volume (30-day avg) 273.7K shares
Beta 0.96
52 Weeks Range 10.20 - 17.15
Updated Date 10/09/2026
52 Weeks Range 10.20 - 17.15
Updated Date 10/09/2026
Dividends yield (FY) -
Basic EPS (TTM) -2.42

How Company Makes Money

Business areaWhat it includesRetail investor read
RoyaltiesRoyalty payments from AbbVie for HCV products.The company receives passive income from historical inventions, which funds current research.
R&D ProgramsClinical and preclinical development of viral and liver disease drugs.The company is a 'bet' on its future scientific breakthroughs, not its current products.

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Advertisement

Valuation

Trailing PE -
Forward PE 44.05
Enterprise Value 214.20M
Price to Sales(TTM) 5.4
Enterprise Value 214.20M
Price to Sales(TTM) 5.4
Enterprise Value to Revenue 3.28
Enterprise Value to EBITDA 41.13
Shares Outstanding 29.13M
Shares Floating 22.52M
Shares Outstanding 29.13M
Shares Floating 22.52M
Percent Insiders 4.67
Percent Institutions 94.39

Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

Form CRS provides a relationship summary of our automated advisory services, flat subscription fees, and conflicts of interest. Form ADV Part 2A brochure contains complete details on services, billing, and disclosures. If any summary differs from our current regulatory filings, the filed Form ADV controls.