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Gossamer Bio Inc (GOSS)

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Upturn Advisory Summary
12/26/2025: GOSS (4-star) is a REGULAR-BUY. BUY since 28 days. Simulated Profits (8.03%). Updated daily EoD!
1 Year Target Price $9.5
1 Year Target Price $9.5
| 4 | Strong Buy |
| 3 | Buy |
| 2 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit 33.89% | Avg. Invested days 29 | Today’s Advisory Regular Buy |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 747.60M USD | Price to earnings Ratio - | 1Y Target Price 9.5 |
Price to earnings Ratio - | 1Y Target Price 9.5 | ||
Volume (30-day avg) 9 | Beta 1.92 | 52 Weeks Range 0.76 - 3.87 | Updated Date 12/27/2025 |
52 Weeks Range 0.76 - 3.87 | Updated Date 12/27/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.69 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -313.21% |
Management Effectiveness
Return on Assets (TTM) -34.25% | Return on Equity (TTM) -783.37% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 770255677 | Price to Sales(TTM) 16.97 |
Enterprise Value 770255677 | Price to Sales(TTM) 16.97 | ||
Enterprise Value to Revenue 17.49 | Enterprise Value to EBITDA -0.39 | Shares Outstanding 231456247 | Shares Floating 188139210 |
Shares Outstanding 231456247 | Shares Floating 188139210 | ||
Percent Insiders 3.92 | Percent Institutions 78.03 |
Upturn AI SWOT
Gossamer Bio Inc

Company Overview
History and Background
Gossamer Bio Inc. was founded in 2017 with the mission to discover, develop, and commercialize therapeutics in immunology and inflammation. The company has since focused on advancing its pipeline of novel drug candidates through clinical development.
Core Business Areas
- Immunology Therapeutics Development: Gossamer Bio Inc. is a clinical-stage biopharmaceutical company focused on developing and commercializing therapeutics in the fields of immunology and inflammation. Their core business involves identifying promising drug candidates and progressing them through preclinical and clinical trials.
Leadership and Structure
Gossamer Bio Inc. is led by a management team with extensive experience in the biopharmaceutical industry. The organizational structure is typical of a growing biotech firm, with departments dedicated to research and development, clinical operations, regulatory affairs, manufacturing, and commercialization.
Top Products and Market Share
Key Offerings
- Product Name 1: GB001 (Nimacimab): A monoclonal antibody targeting the colony-stimulating factor 1 receptor (CSF1R), being developed for the treatment of eosinophilic asthma and other inflammatory conditions. Competitors include other biologic therapies for asthma like Dupixent (sanofi) and Fasenra (AstraZeneca).
- Product Name 2: GB002: A selective inhibitor of phosphodiesterase 4 (PDE4) for the treatment of various inflammatory diseases. Competitors include existing PDE4 inhibitors like Otezla (Amgen) for psoriasis.
- Product Name 3: GB004: A selective inhibitor of alpha V integrins, targeting fibrotic diseases. Competitors include therapies in development for fibrotic conditions like IPF.
Market Dynamics
Industry Overview
The biopharmaceutical industry, particularly in immunology and inflammation, is characterized by high R&D costs, long development cycles, stringent regulatory requirements, and intense competition. The market is driven by the need for novel treatments for chronic and debilitating diseases.
Positioning
Gossamer Bio Inc. positions itself as a company focused on developing innovative therapeutics for unmet needs in immunology and inflammation. Its competitive advantages lie in its targeted approach to drug discovery and development, aiming for high unmet medical needs.
Total Addressable Market (TAM)
The Total Addressable Market for immunology and inflammation therapeutics is substantial, running into tens of billions of dollars globally, driven by the prevalence of diseases like asthma, rheumatoid arthritis, and inflammatory bowel disease. Gossamer Bio Inc. is positioned to target specific segments within this large market with its pipeline candidates, aiming for significant market penetration if successful in clinical development and commercialization.
Upturn SWOT Analysis
Strengths
- Focus on high unmet medical needs in immunology and inflammation.
- Experienced management team with a track record in drug development.
- Pipeline of novel drug candidates with potential for significant therapeutic impact.
- Strategic partnerships and collaborations.
Weaknesses
- Clinical trial risks and uncertainties.
- Reliance on future funding and capital raising.
- Limited commercialization experience compared to larger biopharma companies.
- Drug development is a lengthy and costly process.
Opportunities
- Increasing prevalence of autoimmune and inflammatory diseases.
- Advancements in biotechnology and drug discovery.
- Potential for strategic partnerships and acquisitions.
- Expansion into new therapeutic indications and geographic markets.
Threats
- Failure of drug candidates in clinical trials.
- Regulatory hurdles and delays.
- Intense competition from established pharmaceutical companies and other biotechs.
- Pricing pressures and market access challenges.
- Patent expirations and generic competition for existing therapies.
Competitors and Market Share
Key Competitors
- Vertex Pharmaceuticals (VRTX)
- Gilead Sciences (GILD)
- AbbVie Inc. (ABBV)
- Sanofi (SNY)
- AstraZeneca (AZN)
- Amgen Inc. (AMGN)
Competitive Landscape
Gossamer Bio Inc. faces a highly competitive landscape dominated by large pharmaceutical companies and established biotech firms with extensive resources and existing market presence. Gossamer's advantage lies in its focus on niche areas and novel mechanisms of action, but it must overcome significant hurdles in clinical development and market penetration against well-funded competitors.
Growth Trajectory and Initiatives
Historical Growth: Gossamer Bio Inc.'s growth trajectory has been characterized by the progression of its drug candidates through various stages of clinical development, supported by successful fundraising rounds. Its expansion has been primarily in terms of its pipeline and scientific team.
Future Projections: Future growth projections for Gossamer Bio Inc. are contingent on the successful outcomes of its ongoing and future clinical trials, regulatory approvals, and eventual commercialization of its product candidates. Analyst estimates will vary widely based on the perceived probability of success for each drug.
Recent Initiatives: Recent initiatives likely involve advancing its lead drug candidates through clinical trials, seeking strategic partnerships, and potentially initiating new research programs in immunology and inflammation.
Summary
Gossamer Bio Inc. is a clinical-stage biopharmaceutical company with a focused pipeline in immunology and inflammation. Its strengths lie in its targeted approach and experienced team. However, it faces significant weaknesses due to clinical trial risks and funding needs. Opportunities exist in the growing market for immunology treatments, but threats from competition and regulatory hurdles are substantial. The company's success hinges on the outcomes of its drug development programs.
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Sources and Disclaimers
Data Sources:
- Company Investor Relations
- SEC Filings (10-K, 10-Q)
- Industry Research Reports
- Financial News Outlets
Disclaimers:
This information is for informational purposes only and should not be construed as investment advice. Financial data and market share estimates are subject to change and may not be fully up-to-date. Investors should conduct their own due diligence before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Gossamer Bio Inc
Exchange NASDAQ | Headquaters San Diego, CA, United States | ||
IPO Launch date 2019-02-08 | Co-Founder, CEO, President & Chairman Mr. Faheem Hasnain | ||
Sector Healthcare | Industry Biotechnology | Full time employees 144 | Website https://www.gossamerbio.com |
Full time employees 144 | Website https://www.gossamerbio.com | ||
Gossamer Bio, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing seralutinib for the treatment of pulmonary arterial hypertension (PAH) in the United States. The company is developing GB002, an inhaled, small molecule, platelet-derived growth factor receptor, or PDGFR, colony-stimulatin factor 1 receptor and c-KIT inhibitor, which is in Phase 3 clinical trial for the treatment of PAH. It has license agreements with Pulmokine, Inc. to develop and commercialize GB002 and related backup compounds. The company was formerly known as FSG, Bio, Inc. and changed its name to Gossamer Bio, Inc. in 2017. The company was incorporated in 2015 and is headquartered in San Diego, California.

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