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Upturn AI Summary - About
SeaStar Medical Holding Corporation(ICU)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Stock price based on last close Advisory Performance History (Simulated)
Upturn Advisory & Investor View for ICU
11/02/2026: ICU (1-star) is currently NOT-A-BUY. Pass it for now.
SeaStar Medical Holding Corporation is a clinical-stage medical technology company developing the Selective Cytopheretic Device to treat hyperinflammation in critically ill patients. Its main strength lies in its proprietary platform and FDA breakthrough status, which provide a competitive edge in treating acute organ injury. The primary investment story centers on the potential to capture market share in high-acuity care as it advances from pediatric to adult indications. However, the company faces significant risks related to regulatory hurdles, capital requirements, and intense competition from large established renal care players. The stock may best suit speculative, long-term investors monitoring clinical data milestones and future funding capacity.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Mixed fit | The company offers high growth potential linked to its technology pipeline but lacks established commercial momentum. |
| Momentum investor | Weak fit | The stock has historically experienced high volatility without consistent upward price trends driven by revenue. |
| Value investor | Weak fit | The company does not generate profits, making standard value metrics like P/E ratios inapplicable. |
| Dividend investor | Weak fit | The company does not pay dividends and is currently in a capital-intensive development phase. |
| Low-risk investor | Weak fit | The speculative nature of clinical-stage medical devices carries high investment risk. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | Small-cap clinical-stage stocks often face extreme price swings based on trial news. |
| Valuation risk | High | Valuations are speculative and highly sensitive to regulatory and clinical outcomes. |
| Competition risk (Renal/Critical Care) | High | Incumbent players have significant clinical and market infrastructure advantages. |
| Business quality | Medium | The business relies on a single proprietary platform technology. |
| Dividend income | Low / none | The company reinvests all capital into development. |
| Execution risk | High | Success depends heavily on complex regulatory approvals and clinical trial execution. |
Price Behavior
Rolling Over
The price momentum is slowing down and beginning to turn downward.
Extreme Price Shocks
The stock has experienced exceptionally large and disruptive price movements during the period.
Analysis of Past Performance
Type Stock | Historic Profit -62.4% | Avg. Invested days 15 | Today’s Advisory PASS |
Upturn Advisory Rating  | Upturn Advisory Performance  2.0 | Stock Returns Performance  1.0 |
| Profits based on simulation | Last Close 11/02/2026 |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals
Financial Health Rating
Growth Momentum Score
Ownership
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue)
Economic Dimensions
Quantitative Style Profile
Style Classification
Quality Focused
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 11.64M USD | Price to earnings Ratio - | 1Y Target Price 10 |
Price to earnings Ratio - | 1Y Target Price 10 | ||
Volume (30-day avg) 196.8K shares | Beta -1.04 | 52 Weeks Range 2.07 - 5.63 | Updated Date 11/02/2026 |
52 Weeks Range 2.07 - 5.63 | Updated Date 11/02/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -2.97 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Critical Care Device Sales | Revenue from the sale of the Selective Cytopheretic Device (SCD) for approved clinical applications. | The company generates minimal revenue currently; future upside depends on widespread hospital adoption of its SCD technology. |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 4.85M | Price to Sales(TTM) 6.8 |
Enterprise Value 4.85M | Price to Sales(TTM) 6.8 | ||
Enterprise Value to Revenue 2.83 | Enterprise Value to EBITDA -8.13 | Shares Outstanding 5.32M | Shares Floating 4.37M |
Shares Outstanding 5.32M | Shares Floating 4.37M | ||
Percent Insiders 11.62 | Percent Institutions 7.62 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
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