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Illumina Inc (ILMN)



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Upturn Advisory Summary
07/31/2025: ILMN (2-star) has a low Upturn Star Rating. Not recommended to BUY.
1 Year Target Price $113.77
1 Year Target Price $113.77
7 | Strong Buy |
5 | Buy |
11 | Hold |
2 | Sell |
0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit 29.91% | Avg. Invested days 55 | Today’s Advisory Consider higher Upturn Star rating |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Large-Cap Stock | Market Capitalization 16.26B USD | Price to earnings Ratio 11.98 | 1Y Target Price 113.77 |
Price to earnings Ratio 11.98 | 1Y Target Price 113.77 | ||
Volume (30-day avg) 25 | Beta 1.36 | 52 Weeks Range 68.70 - 156.66 | Updated Date 08/1/2025 |
52 Weeks Range 68.70 - 156.66 | Updated Date 08/1/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) 7.9 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Revenue by Geography
Geography revenue - Year on Year
Earnings Date
Report Date 2025-07-31 | When - | Estimate 1.01 | Actual 1.19 |
Profitability
Profit Margin -22.27% | Operating Margin (TTM) 17.67% |
Management Effectiveness
Return on Assets (TTM) 4.96% | Return on Equity (TTM) -23.85% |
Valuation
Trailing PE 11.98 | Forward PE 24.15 | Enterprise Value 17628993000 | Price to Sales(TTM) 3.75 |
Enterprise Value 17628993000 | Price to Sales(TTM) 3.75 | ||
Enterprise Value to Revenue 4.06 | Enterprise Value to EBITDA 51.88 | Shares Outstanding 158300000 | Shares Floating 153946750 |
Shares Outstanding 158300000 | Shares Floating 153946750 | ||
Percent Insiders 0.19 | Percent Institutions 101.45 |
Upturn AI SWOT
Illumina Inc

Company Overview
History and Background
Illumina Inc. was founded in 1998 and is headquartered in San Diego, California. It is a global leader in DNA sequencing and array-based technologies, serving customers in a wide range of markets, enabling researchers, clinicians, and consumers to gain deeper understanding of the genome.
Core Business Areas
- Sequencing Systems: Develops, manufactures, and markets integrated systems for analyzing genetic variation and function. These systems are used for whole-genome sequencing, targeted sequencing, and gene expression analysis.
- Consumables: Supplies reagents and other consumables necessary to operate Illumina's sequencing and array platforms. Consumables represent a significant portion of Illumina's revenue.
- Services: Offers a range of services, including sequencing services, genotyping services, and data analysis services.
- Software: Provides software solutions for data analysis, interpretation, and management of genomic data.
Leadership and Structure
Illumina is led by Jacob Thaysen, as CEO. The company operates with a traditional corporate structure, with various departments including R&D, Sales & Marketing, Operations, and Finance.
Top Products and Market Share
Key Offerings
- NovaSeq Series: High-throughput sequencing systems used for large-scale genomics projects. Illumina holds a significant market share in the high-throughput sequencing market, estimated to be approximately 70%. Competitors include PacBio and Oxford Nanopore Technologies.
- NextSeq Series: Mid-throughput sequencing systems suitable for a wide range of applications. Competitors include Thermo Fisher Scientific.
- iSeq Series: Low-throughput sequencing systems designed for smaller labs. Competitors include Thermo Fisher Scientific.
- Infinium Arrays: Microarray-based solutions for genotyping and gene expression analysis. Competitors include Thermo Fisher Scientific.
Market Dynamics
Industry Overview
The genomics industry is experiencing rapid growth, driven by increasing adoption of sequencing technologies in research, clinical diagnostics, and drug discovery. Key trends include decreasing sequencing costs, advancements in data analysis, and increasing demand for personalized medicine.
Positioning
Illumina is the dominant player in the DNA sequencing market, with a strong brand reputation, a broad product portfolio, and a large installed base of sequencing systems. Its competitive advantage lies in its proprietary sequencing technologies and its ability to innovate and develop new solutions.
Total Addressable Market (TAM)
The genomics market is estimated to be worth over $50 billion and continues to grow rapidly. Illumina is positioned to capture a significant portion of this market through its leading sequencing platforms and expanding applications.
Upturn SWOT Analysis
Strengths
- Market leader in DNA sequencing
- Strong brand reputation
- Broad product portfolio
- Large installed base
- Proprietary sequencing technologies
Weaknesses
- High cost of sequencing systems
- Dependence on consumables revenue
- Regulatory hurdles in certain markets
- Competition from emerging technologies
- Potential for disruptions in supply chain
Opportunities
- Expanding applications of genomics in clinical diagnostics
- Growth in emerging markets
- Development of new sequencing technologies
- Strategic partnerships and acquisitions
- Increased adoption of personalized medicine
Threats
- Intense competition
- Technological disruptions
- Regulatory changes
- Economic downturns
- Ethical concerns related to genomics
Competitors and Market Share
Key Competitors
- TMO
- PACB
- ONT.L
Competitive Landscape
Illumina maintains a leading position in DNA sequencing, but faces increasing competition. Illumina's large installed base and brand recognition are major assets. TMO has been increasingly successful in capturing market share due to recent innovations in mass spectrometry.
Major Acquisitions
GRAIL
- Year: 2021
- Acquisition Price (USD millions): 7100
- Strategic Rationale: Acquired Grail for early cancer detection using sequencing. The deal is facing regulatory challenges and Illumina is being forced to divest.
Growth Trajectory and Initiatives
Historical Growth: Illumina has experienced strong revenue growth over the past decade, driven by increasing adoption of sequencing technologies. However, growth has slowed in recent years due to increased competition and market saturation.
Future Projections: Analysts expect Illumina to achieve moderate revenue growth in the coming years, driven by expanding applications of genomics and growth in emerging markets. Illustrative data. This is not real-time and up-to-date, but rather for illustrative purposes to demonstrate the proper structure. Replace with actual values. Revenue growth target: [5% - 10%] annually.
Recent Initiatives: Recent initiatives include expanding partnerships, developing new sequencing platforms (e.g. Infinity), and focusing on clinical applications.
Summary
Illumina is the dominant leader in DNA sequencing. Although Illumina's dominance continues to grow, it has been challenged in recent years with its GRAIL acquisition. Key areas of concern include regulatory burdens, competition, and economic downturns. While Illumina continues to innovate, external threats should be considered when assessing the future direction of the firm.
Peer Comparison
Sources and Disclaimers
Data Sources:
- Company Filings
- Analyst Reports
- Industry Publications
- Yahoo Finance
Disclaimers:
The information provided is for informational purposes only and should not be considered as investment advice. Market data is illustrative and may not be real-time. Please consult with a financial professional before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Illumina Inc
Exchange NASDAQ | Headquaters San Diego, CA, United States | ||
IPO Launch date 2000-07-28 | CEO & Director Mr. Jacob Thaysen Ph.D. | ||
Sector Healthcare | Industry Diagnostics & Research | Full time employees 8970 | Website https://www.illumina.com |
Full time employees 8970 | Website https://www.illumina.com |
Illumina, Inc. provides sequencing- and array-based solutions for genetic and genomic analysis in the Americas, Europe, Greater China, the Asia Pacific, the Middle East, and Africa. The company offers sequencing- and array-based instruments and consumables, which include reagents, flow cells, and library preparation; whole-genome sequencing kits, which sequence entire genomes of various size and complexity; and targeted resequencing kits, which sequence exomes, specific genes, and RNA or other genomic regions of interest. It also provides whole-genome sequencing, genotyping, noninvasive prenatal testing, and product support services. The company serves genomic research centers, academic institutions, government laboratories, and hospitals, as well as pharmaceutical, biotechnology, commercial molecular diagnostic laboratories, and consumer genomics companies. The company markets and distributes its products directly to customers, as well as through life-science distributors. Illumina, Inc. was incorporated in 1998 and is headquartered in San Diego, California.

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