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Illumina Inc (ILMN)

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Upturn Advisory Summary
10/30/2025: ILMN (2-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $111.47
1 Year Target Price $111.47
| 7 | Strong Buy |
| 5 | Buy |
| 11 | Hold |
| 2 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit 19.88% | Avg. Invested days 56 | Today’s Advisory PASS |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Large-Cap Stock | Market Capitalization 15.22B USD | Price to earnings Ratio 12.53 | 1Y Target Price 111.47 |
Price to earnings Ratio 12.53 | 1Y Target Price 111.47 | ||
Volume (30-day avg) 25 | Beta 1.4 | 52 Weeks Range 68.70 - 156.66 | Updated Date 10/30/2025 |
52 Weeks Range 68.70 - 156.66 | Updated Date 10/30/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) 7.9 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Revenue by Geography
Geography revenue - Year on Year
Earnings Date
Report Date 2025-11-03 | When After Market | Estimate 1.17 | Actual - |
Profitability
Profit Margin 29.34% | Operating Margin (TTM) 21.15% |
Management Effectiveness
Return on Assets (TTM) 8.84% | Return on Equity (TTM) 68.06% |
Valuation
Trailing PE 12.53 | Forward PE 20.28 | Enterprise Value 16705410000 | Price to Sales(TTM) 3.55 |
Enterprise Value 16705410000 | Price to Sales(TTM) 3.55 | ||
Enterprise Value to Revenue 3.9 | Enterprise Value to EBITDA 9.36 | Shares Outstanding 153700000 | Shares Floating 149330309 |
Shares Outstanding 153700000 | Shares Floating 149330309 | ||
Percent Insiders 0.19 | Percent Institutions 103.95 |
Upturn AI SWOT
Illumina Inc

Company Overview
History and Background
Illumina Inc. was founded in 1998 and is headquartered in San Diego, California. Initially focused on developing DNA sequencing technologies, Illumina has grown through acquisitions and innovation to become a global leader in genomics.
Core Business Areas
- Sequencing Systems: Designs, manufactures, and markets integrated systems for genetic analysis, including sequencers and related consumables.
- Consumables: Provides reagents, flow cells, and other consumables used in Illumina's sequencing systems.
- Services: Offers a range of services, including sequencing, genotyping, and data analysis services to research institutions, pharmaceutical companies, and clinical laboratories.
- Software and Informatics: Develops and markets software and informatics tools for data analysis, interpretation, and management.
Leadership and Structure
Illumina is led by Jacob Thaysen, as CEO. The company has a board of directors overseeing its strategic direction and operations. Its organizational structure is divided into functional areas such as research and development, manufacturing, sales, and marketing.
Top Products and Market Share
Key Offerings
- Market Share (%): 70
- NovaSeq Series: High-throughput sequencing systems used for large-scale genomic studies. Holds a significant market share in high-throughput sequencing. Competitors: PacBio, Oxford Nanopore.
- Market Share (%): 65
- NextSeq Series: Mid-throughput sequencing systems used for a variety of applications. Competitors: Thermo Fisher Scientific.
- Market Share (%): 55
- iSeq Series: Low-throughput sequencing systems used for rapid, targeted sequencing. Competitors: Qiagen, Roche.
- Illumina Connected Analytics: A secure, cloud-based environment for genomic data analysis, management, and collaboration.
Market Dynamics
Industry Overview
The genomics industry is experiencing rapid growth due to advancements in sequencing technologies, increasing demand for personalized medicine, and expanding applications in research, diagnostics, and drug development.
Positioning
Illumina holds a leading position in the genomics market, with a strong brand reputation, advanced technology, and a broad portfolio of products and services. Its competitive advantages include its superior sequencing accuracy, high throughput, and comprehensive solutions.
Total Addressable Market (TAM)
The total addressable market for genomic sequencing is estimated to reach $20 billion+ by 2027. Illumina is positioned well to capture a significant share of this market, targeting clinical diagnostics, research, and agricultural applications.
Upturn SWOT Analysis
Strengths
- Leading Market Position
- Advanced Technology
- Strong Brand Reputation
- Broad Product Portfolio
- Extensive Customer Base
Weaknesses
- High Product Costs
- Dependence on Consumables Sales
- Competition from Emerging Technologies
- Regulatory Risks
Opportunities
- Expanding into Clinical Diagnostics
- Developing New Sequencing Applications
- Growing Demand in Emerging Markets
- Leveraging Data Analytics and AI
Threats
- Increasing Competition
- Price Pressure
- Technological Disruptions
- Economic Downturn
- Data Privacy Concerns
Competitors and Market Share
Key Competitors
- TMO
- PACB
- QGEN
Competitive Landscape
Illumina benefits from a robust product pipeline and overall ecosystem and is still a leader in this competitive landscape. They must continue to watch out for emerging competitors with cheaper technologies.
Major Acquisitions
Pacific Biosciences (Failed)
- Year: 2019
- Acquisition Price (USD millions): 1200
- Strategic Rationale: Aimed to expand Illumina's sequencing capabilities and market share but the deal was terminated due to regulatory concerns.
GRAIL (Divestiture Pending)
- Year: 2021
- Acquisition Price (USD millions): 7100
- Strategic Rationale: Aimed to enter the early cancer detection market; however, regulatory challenges have forced divestiture.
Growth Trajectory and Initiatives
Historical Growth: Illumina has experienced substantial growth over the past decade, driven by increasing adoption of sequencing technologies in research and clinical applications. The growth rate has varied year to year, with periods of rapid expansion followed by periods of slower growth.
Future Projections: Analysts project continued growth for Illumina, driven by expanding applications in clinical diagnostics, drug discovery, and agriculture. Growth projections vary depending on market conditions and competitive dynamics.
Recent Initiatives: Recent initiatives include the development of new sequencing platforms, expansion into new markets, and investments in data analytics and AI.
Summary
Illumina is a dominant player in the genomics industry, driven by its advanced sequencing technologies and broad product portfolio. While the company faces challenges from competition and regulatory issues, its strong market position and focus on innovation position it for continued growth. The company's pending divestiture of GRAIL impacts near term growth and introduces uncertainty. Illumina must adapt to evolving technological landscapes and address regulatory hurdles to maintain its competitive advantage.
Similar Stocks
Sources and Disclaimers
Data Sources:
- Illumina Investor Relations
- SEC Filings
- Analyst Reports
- Industry Research Reports
Disclaimers:
The information provided is for informational purposes only and should not be considered financial advice. Market conditions and company performance are subject to change.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Illumina Inc
Exchange NASDAQ | Headquaters San Diego, CA, United States | ||
IPO Launch date 2000-07-28 | CEO & Director Mr. Jacob Thaysen Ph.D. | ||
Sector Healthcare | Industry Diagnostics & Research | Full time employees 8970 | Website https://www.illumina.com |
Full time employees 8970 | Website https://www.illumina.com | ||
Illumina, Inc. provides sequencing- and array-based solutions for genetic and genomic analysis in the Americas, Europe, Greater China, the Asia Pacific, the Middle East, and Africa. The company offers sequencing- and array-based instruments and consumables, which include reagents, flow cells, and library preparation; whole-genome sequencing kits, which sequence entire genomes of various size and complexity; and targeted resequencing kits, which sequence exomes, specific genes, and RNA or other genomic regions of interest. It also provides whole-genome sequencing, genotyping, noninvasive prenatal testing, and product support services. The company serves genomic research centers, academic institutions, government laboratories, and hospitals, as well as pharmaceutical, biotechnology, commercial molecular diagnostic laboratories, and consumer genomics companies. The company markets and distributes its products directly to customers, as well as through life-science distributors. Illumina, Inc. was incorporated in 1998 and is headquartered in San Diego, California.

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