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IMCR logo IMCR
Upturn stock rating
IMCR logo

Immunocore Holdings Ltd (IMCR)

Upturn stock rating
$33.1
Last Close (24-hour delay)
upturn advisory
PASS
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  • SELL Advisory (Loss)​
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Upturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK

Upturn Advisory Summary

10/24/2025: IMCR (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

17 Analysts rated it

Moderately tracked stock, growing coverage, gaining market and investor attention.

1 Year Target Price $62.2

1 Year Target Price $62.2

Analysts Price Target For last 52 week
$62.2 Target price
52w Low $23.15
Current$33.1
52w High $39.33

Analysis of Past Performance

Type Stock
Historic Profit -10.78%
Avg. Invested days 35
Today’s Advisory PASS
Upturn Star Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance 3.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulation Last Close 10/24/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 1.67B USD
Price to earnings Ratio -
1Y Target Price 62.2
Price to earnings Ratio -
1Y Target Price 62.2
Volume (30-day avg) 17
Beta 0.8
52 Weeks Range 23.15 - 39.33
Updated Date 10/26/2025
52 Weeks Range 23.15 - 39.33
Updated Date 10/26/2025
Dividends yield (FY) -
Basic EPS (TTM) -0.41

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Revenue by Geography

Geography revenue - Year on Year

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -5.7%
Operating Margin (TTM) -15.18%

Management Effectiveness

Return on Assets (TTM) -1.69%
Return on Equity (TTM) -5.43%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 1331812629
Price to Sales(TTM) 4.68
Enterprise Value 1331812629
Price to Sales(TTM) 4.68
Enterprise Value to Revenue 3.74
Enterprise Value to EBITDA -45.82
Shares Outstanding 50387068
Shares Floating 37572629
Shares Outstanding 50387068
Shares Floating 37572629
Percent Insiders 0.03
Percent Institutions 98.17

ai summary icon Upturn AI SWOT

Immunocore Holdings Ltd

stock logo

Company Overview

overview logo History and Background

Immunocore Holdings Ltd was founded in 1999 and is headquartered in Abingdon, UK. It is a commercial-stage biotechnology company pioneering the development of a novel class of TCR bispecific immunotherapies called ImmTAC molecules that are designed to redirect the human immune system to recognize and kill cancer cells.

business area logo Core Business Areas

  • Oncology: Focuses on developing ImmTAC molecules for the treatment of various cancers, including melanoma, non-small cell lung cancer, and other solid tumors.

leadership logo Leadership and Structure

Bahija Jallal serves as Chief Executive Officer. The company has a board of directors and operates with functional departments focused on research and development, clinical operations, commercialization, and finance.

Top Products and Market Share

overview logo Key Offerings

  • Kimmtrak (tebentafusp): Kimmtrak is Immunocore's first commercial product, approved for the treatment of unresectable or metastatic uveal melanoma (mUM). It is the first and only therapy approved for this indication. While specific market share data is variable and evolving, Kimmtrak holds the dominant position in the mUM treatment landscape. Key competitors are traditional chemotherapy regimens and other investigational immunotherapies for solid tumors. Revenue from Kimmtrak continues to grow.

Market Dynamics

industry overview logo Industry Overview

The oncology market is a large and rapidly growing market driven by the increasing prevalence of cancer and advances in cancer therapies. Immunotherapy is a major area of innovation, with TCR-based therapies representing a novel approach.

Positioning

Immunocore is a leader in the development of TCR bispecific immunotherapies. Kimmtrak's approval has established Immunocore as a commercial-stage company with a differentiated technology platform.

Total Addressable Market (TAM)

The TAM for Immunocore's oncology pipeline is significant. The global cancer immunotherapy market size was valued at USD 101.36 billion in 2023 and is projected to grow to USD 266.26 billion by 2032. Immunocore is positioned to capture a share of this expanding market with its ImmTAC technology and pipeline of novel cancer therapies.

Upturn SWOT Analysis

Strengths

  • First-mover advantage in TCR bispecific immunotherapy
  • Approved product (Kimmtrak) with commercial infrastructure
  • Strong intellectual property portfolio
  • Experienced management team
  • Novel ImmTAC platform with broad applicability

Weaknesses

  • Reliance on a single approved product
  • High research and development costs
  • Need for successful clinical trial outcomes for pipeline expansion
  • Competition from established immunotherapy approaches

Opportunities

  • Expansion of Kimmtrak to other indications
  • Advancement of pipeline candidates through clinical development
  • Partnerships with pharmaceutical companies
  • Expansion into new therapeutic areas

Threats

  • Clinical trial failures
  • Regulatory hurdles
  • Competition from other immunotherapy companies
  • Pricing and reimbursement pressures
  • Patent challenges

Competitors and Market Share

competitor logo Key Competitors

  • MRNA
  • PFE
  • BMY
  • NVS

Competitive Landscape

Immunocore is a pioneer in TCR bispecifics, but faces competition from established immunotherapy companies developing checkpoint inhibitors, cell therapies, and other cancer treatments.

Growth Trajectory and Initiatives

Historical Growth: Historical growth is characterized by pipeline development and Kimmtrak commercialization.

Future Projections: Future growth is dependent on the successful development and commercialization of pipeline candidates, as well as continued growth of Kimmtrak sales. Analyst projections are available from financial data providers.

Recent Initiatives: Recent strategic initiatives include clinical trial advancements for pipeline candidates and expansion of the commercial infrastructure.

Summary

Immunocore is a promising biotechnology company with a novel technology platform and a first-in-class product for uveal melanoma. Its strength lies in its innovative technology and commercialized product. However, its reliance on a single product and need for successful clinical trials pose risks. The company needs to carefully manage its resources and focus on expanding its pipeline and market reach.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Immunocore Holdings Ltd. Investor Relations, SEC Filings, Market Reports
  • Company Press Releases

Disclaimers:

This analysis is for informational purposes only and does not constitute investment advice. Market share estimates are approximate and may vary based on the source.

Upturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Immunocore Holdings Ltd

Exchange NASDAQ
Headquaters -
IPO Launch date 2021-02-05
CEO & Executive Director Dr. Bahija Jallal Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 493
Full time employees 493

Immunocore Holdings plc, a commercial-stage biotechnology company, engages in the development of immunotherapies for the treatment of cancer, infectious, and autoimmune diseases. The company offers KIMMTRAK for the treatment of patients with unresectable or metastatic uveal melanoma. It also develops other programs for oncology, including tebentafusp that is in Phase 3 clinical trial to treat advanced cutaneous melanoma and adjuvant uveal melanoma; and brenetafusp that is in Phase 3 clinical trial to treat first-line advanced cutaneous melanoma and in a Phase 1/2 clinical trial in multiple tumor types. In addition, the company's products under development include IMC-R117C (PIWIL-1) that is in Phase 1/2 clinical trial for the treatment of advanced solid tumors, including colorectal cancer; IMC-P115C (PRAME-HLE-A02) that is in Phase 1 clinical trial for patients with tumors that express PRAME; IMC-M113V that is in Phase 1 clinical trials for a potential functional cure in human immunodeficiency virus (HIV); and IMC-I109V that is in Phase 1 clinical trials for a potential functional cure in hepatitis B virus (HBV). Further, it develops IMC-T119C, which is in preclinical trial for multiple solid tumor cancers; IMC-S118AI to treat type 1 diabetes; and IMC-U120AI to treat atopic dermatitis. Immunocore Holdings plc was founded in 1999 and is headquartered in Abingdon, the United Kingdom.