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Jasper Therapeutics Inc (JSPR)


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Upturn Advisory Summary
10/15/2025: JSPR (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $18.29
1 Year Target Price $18.29
7 | Strong Buy |
4 | Buy |
0 | Hold |
0 | Sell |
0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -6.2% | Avg. Invested days 31 | Today’s Advisory PASS |
Upturn Star Rating ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 69.25M USD | Price to earnings Ratio - | 1Y Target Price 18.29 |
Price to earnings Ratio - | 1Y Target Price 18.29 | ||
Volume (30-day avg) 11 | Beta 2.8 | 52 Weeks Range 2.21 - 26.05 | Updated Date 10/17/2025 |
52 Weeks Range 2.21 - 26.05 | Updated Date 10/17/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -6.05 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -73.3% | Return on Equity (TTM) -146.87% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 30221174 | Price to Sales(TTM) - |
Enterprise Value 30221174 | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA -3.42 | Shares Outstanding 27924039 | Shares Floating 13779087 |
Shares Outstanding 27924039 | Shares Floating 13779087 | ||
Percent Insiders 1.05 | Percent Institutions 50.04 |
Upturn AI SWOT
Jasper Therapeutics Inc

Company Overview
History and Background
Jasper Therapeutics, Inc. (JSPR) is a biotechnology company focused on the development and commercialization of novel curative therapies. Founded in 2016, the company is dedicated to improving the lives of patients with hematologic diseases, including those requiring hematopoietic stem cell transplantation.
Core Business Areas
- Hematopoietic Stem Cell Transplantation Conditioning: Jasper Therapeutics is focused on developing conditioning agents to improve the safety and efficacy of stem cell transplantation. Their main product candidate is Briquilimab.
- Precision Medicine: Jasper aims to advance precision medicine approaches to target the underlying causes of diseases.
Leadership and Structure
Ronald Martell serves as the President and CEO. The company has a typical biotech structure with research, development, clinical, and commercial functions.
Top Products and Market Share
Key Offerings
- Briquilimab: Briquilimab is a novel anti-c-KIT antibody designed to clear hematopoietic stem cells from the bone marrow prior to stem cell transplantation. It is intended to improve the safety and tolerability of conditioning regimens. Briquilimab is currently in clinical development for myelodysplastic syndromes (MDS) and severe combined immunodeficiency (SCID). While there is no current market share, competition exists from traditional chemotherapy-based conditioning regimens and other novel approaches being developed by companies like Magenta Therapeutics (MGTA), although Magenta Therapeutics stopped development and is now merged with Dianthus Therapeutics (DNTH).
Market Dynamics
Industry Overview
The industry is in cell and gene therapy conditioning for patients with hematologic diseases. There is a push towards safer conditioning regiments.
Positioning
Jasper is positioned to offer a safer and more targeted alternative to traditional chemotherapy-based conditioning, giving them a competitive advantage for patients where safety is a major concern.
Total Addressable Market (TAM)
The TAM for stem cell transplant conditioning is multi-billion dollar market, and Jasper is positioning Briquilimab to capture a significant portion by offering a safer approach. Precise estimates depend on successful trial results and regulatory approvals.
Upturn SWOT Analysis
Strengths
- Novel therapeutic approach (Briquilimab)
- Experienced management team
- Strong intellectual property portfolio
Weaknesses
- Clinical trial risks
- High cash burn rate
- Reliance on a single product candidate
Opportunities
- Potential to expand Briquilimab's indications
- Partnerships with other companies
- Advancements in precision medicine
Threats
- Competition from established conditioning regimens
- Regulatory hurdles
- Unfavorable clinical trial results
Competitors and Market Share
Key Competitors
- MGTA
- DNTH
- BMY
- MRTX
Competitive Landscape
Jasper competes with established chemotherapy-based regimens and novel therapeutic approaches. Its main advantages would be safety and target specificity. The other competitors listed above are pursuing conditioning regimens or other treatments for hematologic malignancies.
Growth Trajectory and Initiatives
Historical Growth: Historical growth is reflected in the company's progress through clinical trials and financing activities.
Future Projections: Future growth depends on successful clinical trial results and regulatory approvals for Briquilimab. Analyst estimates can be found on financial websites like Yahoo Finance or MarketWatch.
Recent Initiatives: Recent initiatives include ongoing clinical trials of Briquilimab and efforts to expand its potential indications. Monitoring their SEC filings and corporate announcements is key.
Summary
Jasper Therapeutics is a high-risk, high-reward biotechnology company focused on developing Briquilimab for stem cell transplant conditioning. Success hinges on clinical trial outcomes and regulatory approvals. The company has potential due to its targeted approach but faces competition and financial risks, so investors should pay attention to clinical trial data.
Peer Comparison
Sources and Disclaimers
Data Sources:
- Jasper Therapeutics Inc. SEC filings
- Company press releases
- ClinicalTrials.gov
- Financial news sources (e.g., Yahoo Finance, MarketWatch)
Disclaimers:
The information provided is for informational purposes only and should not be considered financial advice. Investment decisions should be made based on thorough research and consultation with a qualified financial advisor. Market share data is estimated and may not be precise.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Jasper Therapeutics Inc
Exchange NASDAQ | Headquaters Redwood City, CA, United States | ||
IPO Launch date 2021-09-24 | President, CEO & Director Mr. Ronald A. Martell | ||
Sector Healthcare | Industry Biotechnology | Full time employees 64 | Website https://jaspertx.com |
Full time employees 64 | Website https://jaspertx.com |
Jasper Therapeutics, Inc., a clinical-stage biotechnology company, focuses on developing therapeutics targeting mast and hematopoietic stem cell driven diseases. The company's lead product candidate is briquilimab, a monoclonal antibody designed to block stem cell factor from binding to and signaling through the CD117 receptor on mast and stem cells. It focuses on the development and commercialization of therapeutic agents for patients with various mast cell driven diseases, including chronic spontaneous urticaria, chronic inducible urticaria, and asthma, as well as conditioning agents for stem cell transplant in patients with sickle cell disease, Fanconi anemia, and severe combined immunodeficiency. Jasper Therapeutics, Inc. was founded in 2018 and is based in Redwood City, California.

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