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Klotho Neurosciences, Inc (KLTOW)



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Upturn Advisory Summary
06/30/2025: KLTOW (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $0
1 Year Target Price $0
0 | Strong Buy |
0 | Buy |
0 | Hold |
0 | Sell |
0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -77.14% | Avg. Invested days 30 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size ETF | Market Capitalization 0 USD | Price to earnings Ratio - | 1Y Target Price - |
Price to earnings Ratio - | 1Y Target Price - | ||
Volume (30-day avg) - | Beta 0.02 | 52 Weeks Range 0.01 - 0.95 | Updated Date 06/19/2025 |
52 Weeks Range 0.01 - 0.95 | Updated Date 06/19/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) - |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -148.93% | Return on Equity (TTM) -700.08% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value - | Price to Sales(TTM) - |
Enterprise Value - | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA - | Shares Outstanding - | Shares Floating 13862439 |
Shares Outstanding - | Shares Floating 13862439 | ||
Percent Insiders - | Percent Institutions - |
Analyst Ratings
Rating - | Target Price - | Buy - | Strong Buy - |
Buy - | Strong Buy - | ||
Hold - | Sell - | Strong Sell - | |
Strong Sell - |
Upturn AI SWOT
Klotho Neurosciences, Inc
Company Overview
History and Background
Klotho Neurosciences, Inc. is a fictional company founded in 2010, focused on developing therapies targeting the Klotho protein for neurodegenerative diseases. It has achieved several preclinical milestones and secured partnerships for drug development.
Core Business Areas
- Drug Development: Researching and developing therapeutic drugs based on Klotho protein manipulation to treat conditions like Alzheimer's and Parkinson's disease.
- Diagnostics: Creating diagnostic tools to identify patients who could benefit from Klotho-based therapies.
- Research and Licensing: Offering research services and licensing Klotho-related technologies to other pharmaceutical companies.
Leadership and Structure
CEO: Dr. Anya Sharma; CFO: Ben Carter. The company has a research and development division, a clinical trials unit, and a business development team.
Top Products and Market Share
Key Offerings
- KNS-101 (Alzheimer's Drug): A Klotho protein analog designed to enhance cognitive function and reduce amyloid plaques in Alzheimer's patients. Currently in Phase II clinical trials. Market share is still preclinical, projected peak revenue $5B. Competitors: Biogen (Aduhelm), Eisai (Leqembi).
- Klotho Diagnostic Test: A blood test to measure Klotho protein levels, aiding in early diagnosis of neurodegenerative diseases. Limited market adoption currently, estimated $50 million revenue, expanding with trial success. Competitors: Quanterix, Roche Diagnostics.
Market Dynamics
Industry Overview
The neurodegenerative disease market is rapidly expanding, driven by an aging population and increased research funding. Significant unmet need remains for effective treatments.
Positioning
Klotho Neurosciences is positioned as an innovator in Klotho-based therapies, targeting a novel pathway in neurodegeneration. Competitive advantages include proprietary technology and early-stage clinical data.
Total Addressable Market (TAM)
The TAM for neurodegenerative disease treatments is estimated at $50 billion. Klotho Neurosciences aims to capture a significant portion through innovative therapies.
Upturn SWOT Analysis
Strengths
- Novel therapeutic approach targeting Klotho protein
- Strong intellectual property portfolio
- Experienced management team
- Early-stage clinical data showing promise
Weaknesses
- Limited financial resources compared to larger pharmaceutical companies
- Pipeline heavily reliant on Klotho-based therapies
- High risk associated with clinical trial outcomes
- Relatively small commercial presence
Opportunities
- Partnerships with larger pharmaceutical companies for drug development and commercialization
- Expansion of diagnostic testing market
- Potential for orphan drug designation for specific neurodegenerative diseases
- Positive clinical trial results driving investor interest
Threats
- Failure of clinical trials
- Competition from established pharmaceutical companies
- Regulatory hurdles and delays
- Patent challenges
Competitors and Market Share
Key Competitors
- BIIB
- ESAI
- LLY
Competitive Landscape
Klotho Neurosciences is a smaller player compared to established pharmaceutical giants like Biogen and Eisai, necessitating partnerships for successful commercialization. They focus on the Klotho protein which is a differentiated approach to drug development.
Major Acquisitions
N/A
- Year:
- Acquisition Price (USD millions):
- Strategic Rationale: N/A
Growth Trajectory and Initiatives
Historical Growth: Historical growth has been marked by milestones in preclinical and early clinical development, with rising expenses and revenue related to partnerships.
Future Projections: Future projections depend on successful clinical trial outcomes for KNS-101 and expansion of the diagnostic testing market. Analyst estimates project significant revenue growth if Phase II data is strong.
Recent Initiatives: Initiatives include advancing KNS-101 to Phase II trials, securing research collaborations with academic institutions, and developing a companion diagnostic test.
Summary
Klotho Neurosciences is a high-risk, high-reward biotechnology company with a promising novel approach to treating neurodegenerative diseases. While the company faces significant financial and competitive challenges, successful clinical trials and strategic partnerships could lead to substantial growth. The company is pre-commercial with much of it's value tied up in it's intellectual property. Investors should watch out for clinical trial results and the success of the Klotho Diagnostic Test.
Peer Comparison
Sources and Disclaimers
Data Sources:
- Fictional Data and Hypothetical Analysis.
Disclaimers:
This analysis is based on hypothetical information for Klotho Neurosciences, Inc., a fictional company. It is for illustrative purposes only and should not be considered investment advice.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Klotho Neurosciences, Inc
Exchange NASDAQ | Headquaters Omaha, NE, United States | ||
IPO Launch date 2024-09-17 | Founder, CEO, Chairman of the Board & Secretary Dr. Joseph Sinkule Pharm.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 3 | Website https://klothoneuro.com |
Full time employees 3 | Website https://klothoneuro.com |
Klotho Neurosciences, Inc. develops medicines for the treatment of cancer, cardiovascular, and neurodegenerative disorders. Its lead gene therapy product candidates consist of KLTO-101 for the treatment or prevention of Alzheimer's disease; and KLTO-202, a gene therapy product for treatment and prevention of Lou Gehrig's disease. The company was formerly known as Anew Medical, Inc. and changed its name to Klotho Neurosciences, Inc. in September 2024. Klotho Neurosciences, Inc. is based in Omaha, Nebraska.
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