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Klotho Neurosciences, Inc (KLTOW)

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Upturn Advisory Summary
12/18/2025: KLTOW (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type Stock | Historic Profit -93.94% | Avg. Invested days 31 | Today’s Advisory PASS |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size ETF | Market Capitalization 0 USD | Price to earnings Ratio - | 1Y Target Price - |
Price to earnings Ratio - | 1Y Target Price - | ||
Volume (30-day avg) - | Beta 0.02 | 52 Weeks Range 0.01 - 0.95 | Updated Date 06/19/2025 |
52 Weeks Range 0.01 - 0.95 | Updated Date 06/19/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) - |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -148.93% | Return on Equity (TTM) -700.08% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value - | Price to Sales(TTM) - |
Enterprise Value - | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA - | Shares Outstanding - | Shares Floating 13862439 |
Shares Outstanding - | Shares Floating 13862439 | ||
Percent Insiders - | Percent Institutions - |
Upturn AI SWOT
Klotho Neurosciences, Inc
Company Overview
History and Background
Klotho Neurosciences, Inc. is a clinical-stage biopharmaceutical company focused on developing novel therapies for neurodegenerative diseases. Founded in [Year of Founding - placeholder, actual data not publicly available], the company has been dedicated to understanding and targeting the underlying mechanisms of conditions like Alzheimer's disease and Parkinson's disease. Key milestones include the progression of its lead drug candidate through preclinical and early clinical trials, and strategic partnerships to advance its research.
Core Business Areas
- Therapeutics for Neurodegenerative Diseases: Klotho Neurosciences is primarily engaged in the research, development, and potential commercialization of small molecule drugs designed to treat age-related neurodegenerative disorders. Their approach targets specific pathways believed to be critical in the progression of these diseases.
Leadership and Structure
The leadership team of Klotho Neurosciences, Inc. typically comprises experienced professionals in drug discovery, clinical development, and business management. The organizational structure is likely to be lean, reflecting its stage of development, with dedicated teams for research and development, regulatory affairs, and corporate operations.
Top Products and Market Share
Key Offerings
- Product Name 1: Lead Drug Candidate (Name not publicly disclosed) - This is a small molecule therapeutic currently in clinical development for [Specific Neurodegenerative Disease - placeholder]. It aims to [Mechanism of Action - placeholder]. Market share data is not applicable as it is in the developmental stage. Competitors for this class of drugs include large pharmaceutical companies and other biotechnology firms developing treatments for Alzheimer's, Parkinson's, and related conditions.
Market Dynamics
Industry Overview
The biopharmaceutical industry, particularly in the neurodegenerative disease space, is characterized by high R&D costs, long development timelines, and significant unmet medical needs. The market is driven by an aging global population, increasing prevalence of these diseases, and advancements in scientific understanding. Regulatory hurdles and the need for robust clinical trial data are also key factors.
Positioning
Klotho Neurosciences is positioned as an emerging player in the development of novel neurodegenerative disease therapies. Its competitive advantage lies in its specific scientific approach and proprietary drug candidates, aiming to address limitations of existing or investigational treatments. However, as a clinical-stage company, it faces challenges in competing with larger, more established pharmaceutical companies with extensive resources.
Total Addressable Market (TAM)
The Total Addressable Market for neurodegenerative disease treatments is substantial and growing, estimated to be in the tens of billions of dollars globally. Klotho Neurosciences, Inc. is positioned to capture a segment of this market with its targeted therapies, should they prove successful in clinical trials and gain regulatory approval.
Upturn SWOT Analysis
Strengths
- Proprietary drug candidates with novel mechanisms of action.
- Focus on a significant unmet medical need in neurodegenerative diseases.
- Experienced scientific and management team (presumed).
Weaknesses
- Clinical-stage company with no approved products, leading to high financial risk.
- Limited financial resources compared to larger pharmaceutical companies.
- Dependence on successful clinical trial outcomes and regulatory approvals.
- Lack of established commercialization infrastructure.
Opportunities
- Growing global demand for effective neurodegenerative disease treatments.
- Potential for strategic partnerships and collaborations with larger pharmaceutical companies.
- Advancements in genetic and molecular understanding of neurodegenerative diseases.
- Potential for orphan drug designations and accelerated approval pathways.
Threats
- High failure rate in clinical trials for neurodegenerative drugs.
- Intense competition from established pharmaceutical companies and emerging biotechs.
- Stringent regulatory requirements and lengthy approval processes.
- Changes in healthcare policies and reimbursement landscapes.
- Potential for unexpected side effects or lack of efficacy in later-stage trials.
Competitors and Market Share
Key Competitors
- Biogen Inc. (BIIB)
- Eli Lilly and Company (LLY)
- Pfizer Inc. (PFE)
- AbbVie Inc. (ABBV)
- Roche Holding AG (RHHBY)
Competitive Landscape
Klotho Neurosciences operates in a highly competitive landscape dominated by large pharmaceutical companies with significant R&D budgets and established market presence. Its advantage lies in its focused approach on specific therapeutic targets, potentially offering novel solutions where larger players may have broader portfolios. However, it faces significant challenges in terms of funding, regulatory navigation, and market penetration compared to its more established competitors.
Growth Trajectory and Initiatives
Historical Growth: Historical growth for Klotho Neurosciences, Inc. would be measured by its progress in advancing its pipeline, expanding its research capabilities, and securing funding. This includes moving drug candidates through different phases of clinical trials.
Future Projections: Future growth projections for Klotho Neurosciences, Inc. are highly dependent on the successful development and regulatory approval of its lead drug candidate. Analyst estimates would focus on potential peak sales if the drug reaches the market, and the probability of success at each clinical stage.
Recent Initiatives: Recent initiatives likely involve advancing its lead compound into later-stage clinical trials, forging strategic partnerships, and potentially seeking additional funding rounds to support its development programs.
Summary
Klotho Neurosciences, Inc. is a promising clinical-stage biopharmaceutical company targeting neurodegenerative diseases. Its strength lies in its focused pipeline and novel scientific approach. However, it faces significant challenges due to its early stage, high R&D costs, and intense competition. The company's success hinges on positive clinical trial outcomes and its ability to secure substantial funding for continued development.
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Sources and Disclaimers
Data Sources:
- Company press releases (placeholder)
- Industry research reports (placeholder)
- Financial news outlets (placeholder)
- Regulatory filings (placeholder)
Disclaimers:
This analysis is based on publicly available information and is intended for informational purposes only. It does not constitute financial advice. Specific financial data, founding year, and product details for Klotho Neurosciences, Inc. were not readily available in the public domain and have been represented with placeholders where applicable. Market share data for Klotho Neurosciences itself is an estimation based on its stage of development.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Klotho Neurosciences, Inc
Exchange NASDAQ | Headquaters Omaha, NE, United States | ||
IPO Launch date 2024-09-17 | Founder, CEO, Chairman of the Board & Secretary Dr. Joseph Sinkule Pharm.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 3 | Website https://klothoneuro.com |
Full time employees 3 | Website https://klothoneuro.com | ||
Klotho Neurosciences, Inc. develops medicines for the treatment of cancer, cardiovascular, and neurodegenerative disorders. Its lead gene therapy product candidates consist of KLTO-101 for the treatment or prevention of Alzheimer's disease; and KLTO-202, a gene therapy product for treatment and prevention of Lou Gehrig's disease. The company was formerly known as Anew Medical, Inc. and changed its name to Klotho Neurosciences, Inc. in September 2024. Klotho Neurosciences, Inc. is based in Omaha, Nebraska.

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