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KLTOW
Upturn stock ratingUpturn stock rating

Klotho Neurosciences, Inc (KLTOW)

Upturn stock ratingUpturn stock rating
$0.25
Last Close (24-hour delay)
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PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
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Upturn Advisory Summary

06/30/2025: KLTOW (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

Analysts rated it

Very few follow this stock; limited insights, higher-risk early investing.

1 Year Target Price $0

1 Year Target Price $0

Analysts Price Target For last 52 week
$0Target price
Low$
Current$0.25
high$

Analysis of Past Performance

Type Stock
Historic Profit -77.14%
Avg. Invested days 30
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 1.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 06/30/2025

Key Highlights

Company Size ETF
Market Capitalization 0 USD
Price to earnings Ratio -
1Y Target Price -
Price to earnings Ratio -
1Y Target Price -
Volume (30-day avg) -
Beta 0.02
52 Weeks Range 0.01 - 0.95
Updated Date 06/19/2025
52 Weeks Range 0.01 - 0.95
Updated Date 06/19/2025
Dividends yield (FY) -
Basic EPS (TTM) -

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -148.93%
Return on Equity (TTM) -700.08%

Valuation

Trailing PE -
Forward PE -
Enterprise Value -
Price to Sales(TTM) -
Enterprise Value -
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -
Shares Outstanding -
Shares Floating 13862439
Shares Outstanding -
Shares Floating 13862439
Percent Insiders -
Percent Institutions -

Analyst Ratings

Rating -
Target Price -
Buy -
Strong Buy -
Buy -
Strong Buy -
Hold -
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Klotho Neurosciences, Inc

stock logo

Company Overview

overview logo History and Background

Klotho Neurosciences, Inc. is a fictional company founded in 2010, focused on developing therapies targeting the Klotho protein for neurodegenerative diseases. It has achieved several preclinical milestones and secured partnerships for drug development.

business area logo Core Business Areas

  • Drug Development: Researching and developing therapeutic drugs based on Klotho protein manipulation to treat conditions like Alzheimer's and Parkinson's disease.
  • Diagnostics: Creating diagnostic tools to identify patients who could benefit from Klotho-based therapies.
  • Research and Licensing: Offering research services and licensing Klotho-related technologies to other pharmaceutical companies.

leadership logo Leadership and Structure

CEO: Dr. Anya Sharma; CFO: Ben Carter. The company has a research and development division, a clinical trials unit, and a business development team.

Top Products and Market Share

overview logo Key Offerings

  • KNS-101 (Alzheimer's Drug): A Klotho protein analog designed to enhance cognitive function and reduce amyloid plaques in Alzheimer's patients. Currently in Phase II clinical trials. Market share is still preclinical, projected peak revenue $5B. Competitors: Biogen (Aduhelm), Eisai (Leqembi).
  • Klotho Diagnostic Test: A blood test to measure Klotho protein levels, aiding in early diagnosis of neurodegenerative diseases. Limited market adoption currently, estimated $50 million revenue, expanding with trial success. Competitors: Quanterix, Roche Diagnostics.

Market Dynamics

industry overview logo Industry Overview

The neurodegenerative disease market is rapidly expanding, driven by an aging population and increased research funding. Significant unmet need remains for effective treatments.

Positioning

Klotho Neurosciences is positioned as an innovator in Klotho-based therapies, targeting a novel pathway in neurodegeneration. Competitive advantages include proprietary technology and early-stage clinical data.

Total Addressable Market (TAM)

The TAM for neurodegenerative disease treatments is estimated at $50 billion. Klotho Neurosciences aims to capture a significant portion through innovative therapies.

Upturn SWOT Analysis

Strengths

  • Novel therapeutic approach targeting Klotho protein
  • Strong intellectual property portfolio
  • Experienced management team
  • Early-stage clinical data showing promise

Weaknesses

  • Limited financial resources compared to larger pharmaceutical companies
  • Pipeline heavily reliant on Klotho-based therapies
  • High risk associated with clinical trial outcomes
  • Relatively small commercial presence

Opportunities

  • Partnerships with larger pharmaceutical companies for drug development and commercialization
  • Expansion of diagnostic testing market
  • Potential for orphan drug designation for specific neurodegenerative diseases
  • Positive clinical trial results driving investor interest

Threats

  • Failure of clinical trials
  • Competition from established pharmaceutical companies
  • Regulatory hurdles and delays
  • Patent challenges

Competitors and Market Share

competitor logo Key Competitors

  • BIIB
  • ESAI
  • LLY

Competitive Landscape

Klotho Neurosciences is a smaller player compared to established pharmaceutical giants like Biogen and Eisai, necessitating partnerships for successful commercialization. They focus on the Klotho protein which is a differentiated approach to drug development.

Major Acquisitions

N/A

  • Year:
  • Acquisition Price (USD millions):
  • Strategic Rationale: N/A

Growth Trajectory and Initiatives

Historical Growth: Historical growth has been marked by milestones in preclinical and early clinical development, with rising expenses and revenue related to partnerships.

Future Projections: Future projections depend on successful clinical trial outcomes for KNS-101 and expansion of the diagnostic testing market. Analyst estimates project significant revenue growth if Phase II data is strong.

Recent Initiatives: Initiatives include advancing KNS-101 to Phase II trials, securing research collaborations with academic institutions, and developing a companion diagnostic test.

Summary

Klotho Neurosciences is a high-risk, high-reward biotechnology company with a promising novel approach to treating neurodegenerative diseases. While the company faces significant financial and competitive challenges, successful clinical trials and strategic partnerships could lead to substantial growth. The company is pre-commercial with much of it's value tied up in it's intellectual property. Investors should watch out for clinical trial results and the success of the Klotho Diagnostic Test.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Fictional Data and Hypothetical Analysis.

Disclaimers:

This analysis is based on hypothetical information for Klotho Neurosciences, Inc., a fictional company. It is for illustrative purposes only and should not be considered investment advice.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Klotho Neurosciences, Inc

Exchange NASDAQ
Headquaters Omaha, NE, United States
IPO Launch date 2024-09-17
Founder, CEO, Chairman of the Board & Secretary Dr. Joseph Sinkule Pharm.D.
Sector Healthcare
Industry Biotechnology
Full time employees 3
Full time employees 3

Klotho Neurosciences, Inc. develops medicines for the treatment of cancer, cardiovascular, and neurodegenerative disorders. Its lead gene therapy product candidates consist of KLTO-101 for the treatment or prevention of Alzheimer's disease; and KLTO-202, a gene therapy product for treatment and prevention of Lou Gehrig's disease. The company was formerly known as Anew Medical, Inc. and changed its name to Klotho Neurosciences, Inc. in September 2024. Klotho Neurosciences, Inc. is based in Omaha, Nebraska.