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KOD logo KOD
Upturn stock rating
KOD logo

Kodiak Sciences Inc (KOD)

Upturn stock rating
$18.69
Last Close (24-hour delay)
Profit since last BUY316.26%
upturn advisory
Strong Buy
BUY since 123 days
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Upturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
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  • WEEK

Upturn Advisory Summary

10/24/2025: KOD (5-star) is a STRONG-BUY. BUY since 123 days. Simulated Profits (316.26%). Updated daily EoD!

Upturn Star Rating

rating

Outstanding Performance

These Stocks/ETFs, based on Upturn Advisory, have historically outperformed the market, making them a top-tier choice for investors.

Number of Analysts

rating

6 Analysts rated it

Limited analyst coverage, niche firm, research info may be scarce.

1 Year Target Price $17.71

1 Year Target Price $17.71

Analysts Price Target For last 52 week
$17.71 Target price
52w Low $1.92
Current$18.69
52w High $20.13

Analysis of Past Performance

Type Stock
Historic Profit 1370.72%
Avg. Invested days 57
Today’s Advisory Strong Buy
Upturn Star Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance 4.0
Stock Returns Performance Upturn Returns Performance 5.0
Upturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulation Last Close 10/24/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 987.24M USD
Price to earnings Ratio -
1Y Target Price 17.71
Price to earnings Ratio -
1Y Target Price 17.71
Volume (30-day avg) 6
Beta 2.68
52 Weeks Range 1.92 - 20.13
Updated Date 10/24/2025
52 Weeks Range 1.92 - 20.13
Updated Date 10/24/2025
Dividends yield (FY) -
Basic EPS (TTM) -3.79

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -39.38%
Return on Equity (TTM) -140.33%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 670442283
Price to Sales(TTM) -
Enterprise Value 670442283
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -0.12
Shares Outstanding 52821689
Shares Floating 29509383
Shares Outstanding 52821689
Shares Floating 29509383
Percent Insiders 5.52
Percent Institutions 79.23

ai summary icon Upturn AI SWOT

Kodiak Sciences Inc

stock logo

Company Overview

overview logo History and Background

Kodiak Sciences Inc. was founded in 2006 and focuses on developing novel therapeutics to treat chronic, high-prevalence retinal diseases. It is known for its Antibody Biopolymer Conjugate (ABC) platform.

business area logo Core Business Areas

  • Retinal Disease Therapeutics: Developing therapies for retinal diseases such as wet age-related macular degeneration (AMD), diabetic macular edema (DME), and retinal vein occlusion (RVO).

leadership logo Leadership and Structure

Victor Perlroth is the CEO. The company has a board of directors and operates with a structure typical of a biotechnology company focused on R&D.

Top Products and Market Share

overview logo Key Offerings

  • Tarcocimab Tedromil (KSI-301): Tarcocimab Tedromil is an investigational anti-VEGF antibody biopolymer conjugate being developed for the treatment of wet AMD, DME, and RVO. There is no market share data for KSI-301 as it is not yet approved. Competitors include Regeneron's Eylea and Roche's Vabysmo.

Market Dynamics

industry overview logo Industry Overview

The retinal disease therapeutics market is large and growing due to the aging population and increasing prevalence of diabetes. It is dominated by anti-VEGF therapies.

Positioning

Kodiak Sciences aims to compete with existing anti-VEGF therapies by offering longer-lasting treatments, potentially reducing the frequency of injections.

Total Addressable Market (TAM)

The global market for retinal disease therapies is expected to reach billions of dollars. Kodiak Sciences aims to capture a significant portion with a longer-lasting treatment.

Upturn SWOT Analysis

Strengths

  • ABC platform technology
  • Potential for less frequent dosing
  • Strong intellectual property portfolio

Weaknesses

  • Dependence on a single lead product candidate
  • High cash burn rate
  • Clinical trial risks and regulatory hurdles

Opportunities

  • Expanding indications for KSI-301
  • Partnerships with larger pharmaceutical companies
  • Developing new therapies using the ABC platform

Threats

  • Competition from established anti-VEGF therapies
  • Clinical trial failures
  • Changes in reimbursement policies

Competitors and Market Share

competitor logo Key Competitors

  • REGN
  • RHHBY

Competitive Landscape

Kodiak Sciences faces strong competition from established players. Its competitive advantage lies in the potential for less frequent dosing.

Growth Trajectory and Initiatives

Historical Growth: Historical growth is characterized by R&D progress and clinical trial milestones.

Future Projections: Future growth depends on the successful development and commercialization of KSI-301 and other pipeline candidates. Analyst estimates vary widely.

Recent Initiatives: Focus on clinical trials for KSI-301 in wet AMD, DME, and RVO.

Summary

Kodiak Sciences is a clinical-stage biotech company with a promising platform technology, but it faces significant risks and competition. Success hinges on the clinical trial results of KSI-301. The company needs to demonstrate a clear advantage over existing therapies to gain market share and should look for partnership opportunities. The balance sheet and cashflow need to be monitored closely.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company SEC filings
  • Company website
  • Analyst reports

Disclaimers:

This analysis is for informational purposes only and should not be considered financial advice. Data may be outdated.

Upturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Kodiak Sciences Inc

Exchange NASDAQ
Headquaters Palo Alto, CA, United States
IPO Launch date 2018-10-04
Co-Founder, Chairman, CEO & President Dr. Victor Perlroth M.D.
Sector Healthcare
Industry Biotechnology
Full time employees 121
Full time employees 121

Kodiak Sciences Inc., a clinical stage biopharmaceutical company, engages in the research, development, and commercialization of therapeutics to treat retinal diseases. Its lead product candidate is tarcocimab tedromer (KSI-301), an anti-vascular endothelial growth factor (VEGF) antibody biopolymer that has complete Phase 3 clinical study to treat high prevalence retinal vascular diseases; and in Phase 3 clinical study for the treatment of diabetic retinopathy, wet age-related macular degeneration (AMD), retinal vein occlusion, and diabetic macular edema, as well as in Phase 2/3 clinical study to treat wet AMD. The company's preclinical stage product candidate includes KSI-501, an anti- interleukin-6 (IL-6) and VEGF-trap bispecific antibody biopolymer conjugate for high prevalence retinal vascular diseases; and KSI-101 (KSI-501P), an unconjugated bispecific protein targeting IL-6 and VEGF developed for patients who have retinal fluid and inflammation. The company was formerly known as Oligasis, LLC and changed its name to Kodiak Sciences Inc. in September 2015. Kodiak Sciences Inc. was incorporated in 2009 and is based in Palo Alto, California.