Kazia Therapeutics Ltd ADR logo

Kazia Therapeutics Ltd ADR(KZIA)

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EXPLORE ADVISORIES AND THEIR HISTORY
QUALITY SIGNAL
1-STAR RATING
PASS
LAST CLOSE
$7.81
10/23/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
  • ALL
  • 1Y
  • 1M
  • 1W
  • BUY Advisory
  • SELL Advisory (Profit)
  • SELL Advisory (Loss)
  • Profit
  • Loss
  • PASS (Skip)
Upturn Stock price based on last close iconStock price based on last close
Simulated performance—not actual client returns. Excludes advisory subscription fees, trading commissions, and taxes, which would reduce returns. Results depend on calculation assumptions and do not guarantee future outcomes. See Disclosures for full methodology, assumptions, and limitations.

Advisory Performance History (Simulated)Advisory Performance History info

Simulated performance—not actual client returns. Excludes advisory subscription fees, trading commissions, and taxes, which would reduce returns. Results depend on calculation assumptions and do not guarantee future outcomes. See Disclosures for full methodology, assumptions, and limitations.

Upturn Advisory & Investor View for KZIA

10/23/2026: KZIA (1-star) is currently NOT-A-BUY. Pass it for now.

Kazia Therapeutics is a clinical-stage biotechnology company focused on developing specialized treatments for rare and aggressive oncology conditions like glioblastoma. The company's primary strength lies in its targeted pipeline, notably its lead candidate Paxalisib, and its ability to secure promising drug assets through strategic in-licensing. The core investment story centers on the potential for successful clinical readouts to significantly enhance asset value or trigger acquisition interest. However, the company faces substantial execution, financial, and clinical risks, as it does not yet have commercialized products. It is suited for investors with a high risk tolerance, and key developments to monitor include clinical trial milestones and future funding updates.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorMixed fitThe growth potential is high but speculative, dependent entirely on binary clinical outcomes.
Momentum investorWeak fitThis stock is generally unsuitable for momentum strategies unless specific positive clinical trial results trigger short-term buying.
Value investorWeak fitThe lack of consistent earnings and revenue makes traditional value metrics inapplicable.
Dividend investorWeak fitThe company does not pay dividends and retains all capital for R&D.
Low-risk investorWeak fitThe high volatility and clinical risk make this unsuitable for conservative portfolios.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighClinical trial outcomes frequently lead to sharp, dramatic share price swings.
Valuation riskHighValuation is based on long-term potential, making it highly sensitive to changes in clinical sentiment.
Competition risk (Oncology/Drug dev)HighLarge incumbents have significantly more resources to capture market share.
Business qualityMediumThe company is a pure-play R&D firm with no commercialized product moat.
Dividend incomeLow / noneDividends are non-existent and not expected in the foreseeable future.
Execution riskHighSuccess depends entirely on the technical and regulatory achievement of clinical milestones.

Price Behavior

Rolling Over
PRICE PATH

Rolling Over

The price momentum is slowing down and beginning to turn downward.

Extreme Price Shocks
PRICE STABILITY

Extreme Price Shocks

The stock has experienced exceptionally large and disruptive price movements during the period.

Analysis of Past Performance

Type Stock
Historic Profit -33.94%
Avg. Invested days 11
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 2.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 10/23/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
KZIA receives a 3-star rating, supported by solid analyst coverage. The rating is constrained by soft unit economics, soft quantitative characteristics, and weak price momentum.

Company Fundamentals

★★★★★
KZIA has moderate overall fundamentals (3 stars), with soft financial health, soft growth momentum, and solid ownership. In FY2025 versus FY2024, solid earnings growth (+22.7%) is partially offset by weak cash generation (FCF margin -31614.3%), negative revenue growth (-98.2%), weak profitability (net margin -49290.5%).

Financial Health Rating

★★★★★
KZIA's financial health is soft, with the relatively strongest area being moderate efficiency, including operating-expense and cost-of-revenue discipline (opex 33950.0% of revenue). Liquidity is soft (2 stars), which helps explain the 2-star overall score.

Growth Momentum Score

★★★★★
Earnings growth is KZIA's strongest growth driver at +22.7% FY2025 versus FY2024 (solid, 4 stars). By comparison, while revenue growth (-98.2%, negative) and free-cash-flow growth (-38.6%, negative) hold the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 32.2% and approximately 82.2% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 15.42% supports management-shareholder alignment.

Top 5 Institutional Investors

Boxer Capital Management, LLC 4.33%
F.L.Putnam Investment Management 3.21%
Bleichroeder LP 3.09%
Ikarian Capital, LLC 3.06%
Dauntless Investment Group, LLC 2.74%

Unit Economics (Per $1K Revenue)

★★★★★
KZIA generates approximately $1,000 of gross profit, $-338,500 of operating income, and $-316,143 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Operating losses and cash burn explain the 2-star rating, with weak cash conversion and strong capital efficiency.

Economic Dimensions

★★★★★
Effective Tax Rate: 7.78%

Quantitative Style Profile

★★★★★
KZIA has a liquid profile. Weak momentum is the primary drawback, while soft valuation.

Style Classification

Quality Focused

High VolatilitySmall / Mid Cap RiskShort Squeeze RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 89.24M USD
Price to earnings Ratio -
1Y Target Price 29.67
Price to earnings Ratio -
1Y Target Price 29.67
Volume (30-day avg) 261.4K shares
Beta 2.27
52 Weeks Range 4.86 - 17.40
Updated Date 10/24/2026
52 Weeks Range 4.86 - 17.40
Updated Date 10/24/2026
Dividends yield (FY) -
Basic EPS (TTM) -6.85

How Company Makes Money

Business areaWhat it includesRetail investor read
Oncology Research & DevelopmentClinical trial activities for candidates like Paxalisib.The company currently makes no profit; it survives on investor funding to pay for expensive medical research.

Analyzing Revenue: Products, Geography and Growth

Revenue by Geography

Geography revenue - Year on Year

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Valuation

Trailing PE -
Forward PE 12.82
Enterprise Value 8.61M
Price to Sales(TTM) 47
Enterprise Value 8.61M
Price to Sales(TTM) 47
Enterprise Value to Revenue 5.64
Enterprise Value to EBITDA -0.71
Shares Outstanding 11.43M
Shares Floating 9.39M
Shares Outstanding 11.43M
Shares Floating 9.39M
Percent Insiders 15.42
Percent Institutions 32.17

Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

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