Upturn unsubscribed user
$1.14/ day, billed weekly
Cancel anytime
(Ad-Free, Unlimited access)​
NO CREDIT CARD REQUIRED
LIXTW logo LIXTW
Upturn stock ratingUpturn stock rating
LIXTW logo

Lixte Biotechnology Holdings Inc (LIXTW)

Upturn stock ratingUpturn stock rating
$0.03
Last Close (24-hour delay)
upturn advisory
PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK

Upturn Advisory Summary

06/30/2025: LIXTW (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

Analysts rated it

Very few follow this stock; limited insights, higher-risk early investing.

1 Year Target Price $0

1 Year Target Price $0

Analysts Price Target For last 52 week
$0Target price
Low$
Current$0.03
high$

Analysis of Past Performance

Type Stock
Historic Profit -60%
Avg. Invested days 26
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 1.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 06/30/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 39.49M USD
Price to earnings Ratio -
1Y Target Price -
Price to earnings Ratio -
1Y Target Price -
Volume (30-day avg) -
Beta 0.37
52 Weeks Range 0.02 - 0.09
Updated Date 06/21/2025
52 Weeks Range 0.02 - 0.09
Updated Date 06/21/2025
Dividends yield (FY) -
Basic EPS (TTM) -

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -81.14%
Return on Equity (TTM) -155.14%

Valuation

Trailing PE -
Forward PE -
Enterprise Value -
Price to Sales(TTM) -
Enterprise Value -
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -
Shares Outstanding -
Shares Floating 2527941
Shares Outstanding -
Shares Floating 2527941
Percent Insiders -
Percent Institutions -

Analyst Ratings

Rating -
Target Price -
Buy -
Strong Buy -
Buy -
Strong Buy -
Hold -
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Lixte Biotechnology Holdings Inc

stock logo

Company Overview

overview logo History and Background

Lixte Biotechnology Holdings Inc. was founded in 2005 and is focused on discovering and developing novel small molecule drugs for use in cancer treatment. The company's primary focus has been on developing drugs that target protein phosphatase 2A (PP2A).

business area logo Core Business Areas

  • Drug Development: Lixte Biotechnology is focused on the research and development of new drugs for cancer treatment. Their main focus is on PP2A inhibition.
  • Clinical Trials: The company engages in clinical trials to test the safety and effectiveness of its drug candidates.
  • Licensing: Lixte seeks to license its drug candidates to larger pharmaceutical companies for further development and commercialization.

leadership logo Leadership and Structure

The leadership team is comprised of experienced scientists and business executives. The company operates with a research-focused organizational structure.

Top Products and Market Share

overview logo Key Offerings

  • LB-100: LB-100 is Lixte's lead drug candidate, a PP2A inhibitor. It's currently in clinical trials for various cancer types. Market share data specific to LB-100 is not available due to its developmental stage. Competitors are larger pharmaceutical companies developing cancer therapies, such as Pfizer, Merck, and Novartis

Market Dynamics

industry overview logo Industry Overview

The pharmaceutical industry, particularly the oncology segment, is highly competitive and characterized by significant research and development investments. Demand for new and effective cancer treatments is high.

Positioning

Lixte is a small biotechnology company focusing on a specific target (PP2A) within the oncology space. Its competitive advantage, if any, lies in the uniqueness and potential efficacy of its PP2A inhibitor.

Total Addressable Market (TAM)

The global oncology market is estimated to be worth hundreds of billions of dollars. Lixte is positioned to capture a small fraction of this market if LB-100 proves successful. The success of Lixte depends on positive clinical trial results.

Upturn SWOT Analysis

Strengths

  • Novel drug target (PP2A)
  • Lead drug candidate in clinical trials
  • Experienced scientific team

Weaknesses

  • Limited financial resources
  • Reliance on a single drug candidate
  • Small company size

Opportunities

  • Positive clinical trial results
  • Partnership with a larger pharmaceutical company
  • Expansion to other cancer types

Threats

  • Clinical trial failures
  • Competition from larger pharmaceutical companies
  • Regulatory hurdles
  • Financial constraints

Competitors and Market Share

competitor logo Key Competitors

  • PFE
  • MRK
  • NVS
  • BMY
  • AZN

Competitive Landscape

Lixte is a small player compared to its larger competitors. Its success depends on demonstrating superior efficacy or safety with its PP2A inhibitor.

Growth Trajectory and Initiatives

Historical Growth: Historical growth is characterized by research and development milestones, rather than revenue growth.

Future Projections: Future growth is contingent on the success of LB-100 and other drug candidates in clinical trials. Analyst estimates are speculative and subject to significant uncertainty.

Recent Initiatives: Recent initiatives include progressing LB-100 through clinical trials and seeking partnerships for further development.

Summary

Lixte Biotechnology is a high-risk, high-reward development-stage company focused on novel cancer therapeutics. The company's fate hinges on the success of its lead drug candidate, LB-100. Limited financial resources and intense competition pose significant challenges. Positive clinical trial results and strategic partnerships are crucial for future growth and survival.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company filings, Press releases, Analyst reports (where available)

Disclaimers:

This analysis is based on publicly available information and is not financial advice. Investment decisions should be made after consulting with a qualified financial advisor.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Lixte Biotechnology Holdings Inc

Exchange NASDAQ
Headquaters Pasadena, CA, United States
IPO Launch date 2020-11-25
CEO & Chairman Mr. Geordan G. Pursglove
Sector Healthcare
Industry Biotechnology
Full time employees 2
Full time employees 2

Lixte Biotechnology Holdings, Inc., a clinical-stage biopharmaceutical company, focuses on identifying targets for cancer drug development, and developing and commercializing cancer therapies. Its lead product candidate, LB-100 is in phase 1b clinical trials combined with Atezolizumab for patients with microsatellite stable metastatic colorectal cancer. The company's LB-100 combined with doxorubicin in advanced soft tissue sarcoma is under Phase 1b portion; and LB-100 combined with dostarlimab that is in phase 1b/2 for ovarian clear cell carcinoma. The company has a clinical trial research agreement with the Netherlands Cancer Institute; collaboration agreement for an investigator-initiated clinical trial with the Spanish Sarcoma Group; and a development collaboration agreement with the Netherlands Cancer Institute. Lixte Biotechnology Holdings, Inc. was founded in 2005 and is based in Pasadena, California.