LVTX official logo LVTX
LVTX 1-star rating from Upturn Advisory
LAVA Therapeutics NV (LVTX) company logo

LAVA Therapeutics NV (LVTX)

LAVA Therapeutics NV (LVTX) 1-star rating from Upturn Advisory
$1.62
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Upturn Advisory Summary

11/05/2025: LVTX (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

Upturn 1 star rating for performance

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

1 star rating from financial analysts

4 Analysts rated it

Very few follow this stock; limited insights, higher-risk early investing.

1 Year Target Price $1.36

1 Year Target Price $1.36

Analysts Price Target For last 52 week
$1.36 Target price
52w Low $0.85
Current$1.62
52w High $2

Analysis of Past Performance

Type Stock
Historic Profit 11.31%
Avg. Invested days 54
Today’s Advisory PASS
Upturn Star Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 3.0
Stock Returns Performance Upturn Returns Performance icon 2.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 11/05/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 42.75M USD
Price to earnings Ratio -
1Y Target Price 1.36
Price to earnings Ratio -
1Y Target Price 1.36
Volume (30-day avg) 4
Beta 0.5
52 Weeks Range 0.85 - 2.00
Updated Date 11/5/2025
52 Weeks Range 0.85 - 2.00
Updated Date 11/5/2025
Dividends yield (FY) -
Basic EPS (TTM) -1.06

Analyzing Revenue: Products, Geography and Growth

Revenue by Geography

Earnings Date

Report Date 2025-11-12
When -
Estimate -0.245
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -521.84%

Management Effectiveness

Return on Assets (TTM) -21.3%
Return on Equity (TTM) -90.19%

Valuation

Trailing PE -
Forward PE -
Enterprise Value -15395793
Price to Sales(TTM) 8.57
Enterprise Value -15395793
Price to Sales(TTM) 8.57
Enterprise Value to Revenue 2.12
Enterprise Value to EBITDA 0.81
Shares Outstanding 26305295
Shares Floating 17407792
Shares Outstanding 26305295
Shares Floating 17407792
Percent Insiders 16.8
Percent Institutions 28.43

Icon representing Upturn AI-generated SWOT analysis summary Upturn AI SWOT

LAVA Therapeutics NV

LAVA Therapeutics NV(LVTX) company logo displayed in Upturn AI summary

Company Overview

Company history and background logo History and Background

LAVA Therapeutics NV is a biotechnology company focused on developing bispecific gamma-delta T cell engagers to treat cancer. Founded in 2017, it has focused on translating its innovative platform into clinical programs.

Company business area logo Core Business Areas

  • Gamma-delta T cell engagers: LAVA develops bispecific antibodies that bind to gamma-delta T cells and tumor-associated antigens, activating the T cells to kill cancer cells.
  • Clinical Programs: The company is advancing a pipeline of novel gamma-delta T cell engagers for the treatment of solid tumors and hematological malignancies.

leadership logo Leadership and Structure

The leadership team consists of experienced pharmaceutical executives and scientists. The company has a research and development focused organizational structure.

Top Products and Market Share

Product Key Offerings logo Key Offerings

  • LAVA-051: A bispecific gamma-delta T cell engager targeting CD1d for the treatment of certain hematological malignancies, including multiple myeloma, chronic lymphocytic leukemia and acute myeloid leukemia. Phase 1/2a clinical trial in progress. Competitors: Other companies developing bispecific antibodies and cell therapies.
  • LAVA-1207: A bispecific gamma-delta T cell engager targeting EGFR for the treatment of solid tumors. Phase 1/2a clinical trial planned. Competitors: Companies developing EGFR-targeted therapies, including monoclonal antibodies and tyrosine kinase inhibitors.

Market Dynamics

industry overview logo Industry Overview

The biotechnology industry is highly competitive, with numerous companies developing new cancer therapies. There's a growing interest in immunotherapy and cell-based therapies.

Positioning

LAVA Therapeutics is positioned as an innovator in the field of gamma-delta T cell engagers. Its competitive advantage lies in its proprietary platform technology.

Total Addressable Market (TAM)

The total addressable market for cancer therapies is vast, estimated in the hundreds of billions of dollars. LAVA Therapeutics is targeting specific subsets of cancers with unmet needs, positioning it to capture a portion of this market.

Upturn SWOT Analysis

Strengths

  • Proprietary gamma-delta T cell engager platform
  • Experienced management team
  • Novel approach to cancer immunotherapy
  • Early clinical data showing promise

Weaknesses

  • Limited financial resources compared to larger pharmaceutical companies
  • Early stage clinical development
  • High risk of clinical trial failure
  • Reliance on external collaborations

Opportunities

  • Potential to develop first-in-class cancer therapies
  • Strategic partnerships with larger pharmaceutical companies
  • Expansion of pipeline to new cancer targets
  • Positive clinical trial results driving market value

Threats

  • Competition from established cancer therapies
  • Regulatory hurdles and approval delays
  • Clinical trial failures
  • Changes in the competitive landscape

Competitors and Market Share

Key competitor logo Key Competitors

  • AGEN
  • XOMA
  • GTHX

Competitive Landscape

LAVA Therapeutics competes with larger pharmaceutical companies and other biotechnology firms developing cancer immunotherapies. Its strength lies in its innovative gamma-delta T cell engager platform, but it faces challenges related to funding and clinical development.

Growth Trajectory and Initiatives

Historical Growth: LAVA Therapeutics' growth has been characterized by preclinical and early clinical development progress.

Future Projections: Future growth depends on the successful development and commercialization of its gamma-delta T cell engagers. Analyst estimates vary depending on clinical trial outcomes.

Recent Initiatives: Recent initiatives include advancing its lead clinical programs (LAVA-051 and LAVA-1207) and expanding its research and development pipeline.

Summary

LAVA Therapeutics is a clinical-stage biotech company with a novel platform for developing gamma-delta T cell engagers. The company is in an early stage with no product on the market, but it has promising clinical data, an experienced team, and a clear path to commercializing their therapies. However, it is exposed to high competition and will need to manage its cash burn rate.

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Sources and Disclaimers

Data Sources:

  • Company website
  • SEC filings
  • Analyst reports

Disclaimers:

The data provided is for informational purposes only and should not be considered investment advice. Investment decisions should be based on thorough research and consultation with a financial advisor.

Information icon for Upturn AI Summarization accuracy disclaimer AI Summarization is directionally correct and might not be accurate.

Information icon for Upturn AI Summarization data freshness disclaimer Summarized information shown could be a few years old and not current.

Information icon warning about Upturn AI Fundamental Rating based on potentially old data Fundamental Rating based on AI could be based on old data.

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About LAVA Therapeutics NV

Exchange NASDAQ
Headquaters -
IPO Launch date 2021-03-25
CEO, President & Executive Director Mr. Stephen Allen Hurly M.B.A., M.Sc.
Sector Healthcare
Industry Biotechnology
Full time employees 34
Full time employees 34

LAVA Therapeutics N.V. operates as a clinical-stage immuno-oncology company that focuses on developing cancer treatments. The company through its Gammabody platform, develops a portfolio of novel bispecific antibodies to engage and leverage the potency and precision of gamma delta T cells to elicit an anti-tumor immune response and enhance outcomes for cancer patients. Its lead clinical-stage candidates are LAVA-1207 that is in Phase 1/2a clinical trial for metastatic castration-resistant prostate cancer. The company is developing other Gammabody drug candidates, which include LAVA-1223, which targets the epidermal growth factor receptor (EGFR) for the treatment of selected solid tumors, as well as LAVA-1266 which are preclinical candidates for the treatment of various hematologic malignancies. The company has a research collaboration and license agreement with Janssen Biotech, Inc. for the potential discovery and development of multi-specific antibody products that are directed to a specified target in various fields of use; and a collaboration with Merck & Co., Inc. to evaluate anti-PD-1 therapy KEYTRUDA in combination with LAVA-1207. LAVA Therapeutics N.V. was incorporated in 2016 and is based in Utrecht, the Netherlands.