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LYRA 1-star rating from Upturn Advisory
Lyra Therapeutics Inc (LYRA) company logo

Lyra Therapeutics Inc (LYRA)

Lyra Therapeutics Inc (LYRA) 1-star rating from Upturn Advisory
$3.64
Last Close (24-hour delay)
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PASS
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*as per simulation
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Upturn Advisory Summary

12/12/2025: LYRA (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

Upturn 1 star rating for performance

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

1 star rating from financial analysts

4 Analysts rated it

Very few follow this stock; limited insights, higher-risk early investing.

1 Year Target Price $11.5

1 Year Target Price $11.5

Analysts Price Target For last 52 week
$11.5 Target price
52w Low $2.84
Current$3.64
52w High $34

Analysis of Past Performance

Type Stock
Historic Profit -10.25%
Avg. Invested days 25
Today’s Advisory PASS
Upturn Star Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 2.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 12/12/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 6.45M USD
Price to earnings Ratio -
1Y Target Price 11.5
Price to earnings Ratio -
1Y Target Price 11.5
Volume (30-day avg) 4
Beta -0.01
52 Weeks Range 2.84 - 34.00
Updated Date 12/14/2025
52 Weeks Range 2.84 - 34.00
Updated Date 12/14/2025
Dividends yield (FY) -
Basic EPS (TTM) -22.9

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -25032%

Management Effectiveness

Return on Assets (TTM) -33.08%
Return on Equity (TTM) -404.48%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 15775696
Price to Sales(TTM) 10.75
Enterprise Value 15775696
Price to Sales(TTM) 10.75
Enterprise Value to Revenue 26.29
Enterprise Value to EBITDA 0.66
Shares Outstanding 1774882
Shares Floating 1506591
Shares Outstanding 1774882
Shares Floating 1506591
Percent Insiders 0.62
Percent Institutions 19.77

About Lyra Therapeutics Inc

Exchange NASDAQ
Headquaters Watertown, MA, United States
IPO Launch date 2020-05-01
CEO, President & Chairman Dr. Maria Palasis Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 30
Full time employees 30

Lyra Therapeutics, Inc., a clinical-stage biotechnology company, focuses on the development and commercialization of anti-inflammatory therapies for the treatment of patients with chronic rhinosinusitis. Its technology is designed to deliver medicines directly to the affected tissue for sustained periods with a single administration. The company's product candidates include LYR-210, an anti-inflammatory implantable drug matrix which is in Phase III clinical trial for the treatment of chronic rhinosinusitis (CRS); and LYR-220 for CRS patients who have failed previous medical management and continue to require treatment to manage CRS symptoms. It has a collaboration agreement with LianBio Inflammatory Limited to develop and commercialize LYR-210 in mainland China, Hong Kong, Taiwan, Macau, South Korea, Singapore, and Thailand. The company was formerly known as 480 Biomedical, Inc. and changed its name to Lyra Therapeutics, Inc. in July 2018. Lyra Therapeutics, Inc. was incorporated in 2005 and is headquartered in Watertown, Massachusetts.