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MAIA Biotechnology Inc. (MAIA)


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Upturn Advisory Summary
10/15/2025: MAIA (1-star) has a low Upturn Star Rating. Not recommended to BUY.
1 Year Target Price $12.13
1 Year Target Price $12.13
1 | Strong Buy |
0 | Buy |
0 | Hold |
0 | Sell |
0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -32.62% | Avg. Invested days 23 | Today’s Advisory WEAK BUY |
Upturn Star Rating ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 44.54M USD | Price to earnings Ratio - | 1Y Target Price 12.13 |
Price to earnings Ratio - | 1Y Target Price 12.13 | ||
Volume (30-day avg) 1 | Beta 0.03 | 52 Weeks Range 1.27 - 3.48 | Updated Date 10/17/2025 |
52 Weeks Range 1.27 - 3.48 | Updated Date 10/17/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.54 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -107.22% | Return on Equity (TTM) -459.53% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 49243274 | Price to Sales(TTM) - |
Enterprise Value 49243274 | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA -2.34 | Shares Outstanding 32993220 | Shares Floating 28320720 |
Shares Outstanding 32993220 | Shares Floating 28320720 | ||
Percent Insiders 21.43 | Percent Institutions 6.93 |
Upturn AI SWOT
MAIA Biotechnology Inc.
Company Overview
History and Background
MAIA Biotechnology, Inc. is a clinical-stage biopharmaceutical company founded in 2016 and focused on developing targeted cancer therapies using its proprietary Targeted G-quadruplex (TGQ) technology.
Core Business Areas
- Drug Development: Focuses on developing novel drugs for the treatment of cancer, with a primary focus on telomere targeting.
- Clinical Trials: Conducting clinical trials to evaluate the safety and efficacy of their drug candidates.
Leadership and Structure
Vlad Vitoc is Chairman, President and CEO. They have a board of directors overseeing strategic direction.
Top Products and Market Share
Key Offerings
- THIO-101: A telomere-targeting agent in clinical development for advanced cancers. Currently in Phase 2 trials for small cell lung cancer (SCLC). Market share and revenue are currently not available as it is still in the clinical trial phase. Competitors include companies developing treatments for SCLC, such as Bristol Myers Squibb and AstraZeneca.
Market Dynamics
Industry Overview
The biopharmaceutical industry is highly competitive and research-intensive, with a focus on developing innovative therapies for unmet medical needs. Companies face risks related to clinical trial outcomes, regulatory approvals, and market access.
Positioning
MAIA Biotechnology is a small, clinical-stage company focused on a specific area of cancer therapy (telomere targeting). It is positioned as an innovator with a novel technology, but it also faces significant risks and challenges associated with drug development.
Total Addressable Market (TAM)
The global oncology market is estimated to be worth hundreds of billions of dollars. MAIA Biotechnology's TAM depends on the success of THIO-101 and other pipeline products in specific cancer indications. While the exact TAM is not available due to the early stage, SCLC represents a significant market.
Upturn SWOT Analysis
Strengths
- Proprietary TGQ platform
- Targeted cancer therapy approach
- Experienced management team
- THIO-101 in Phase 2 trials
Weaknesses
- Limited financial resources
- Reliance on a single drug candidate
- High risk of clinical trial failure
- Small company size
Opportunities
- Positive clinical trial results
- Partnerships with larger pharmaceutical companies
- Expansion into new cancer indications
- Potential for orphan drug designation
Threats
- Competition from established pharmaceutical companies
- Regulatory hurdles
- Unfavorable clinical trial outcomes
- Market access challenges
Competitors and Market Share
Key Competitors
- BMY
- AZN
- MRTX
- RPTX
Competitive Landscape
MAIA Biotechnology faces intense competition from larger, more established pharmaceutical companies with greater resources and broader product portfolios. Its competitive advantage lies in its novel TGQ platform and targeted therapy approach. It is too early to tell how they will be able to capture their niche within the market.
Growth Trajectory and Initiatives
Historical Growth: Historical growth has been characterized by preclinical and early clinical development activities.
Future Projections: Future growth is highly dependent on the successful development and commercialization of THIO-101 and other pipeline products. Analyst estimates vary widely due to the inherent uncertainty in drug development.
Recent Initiatives: Recent initiatives include advancing THIO-101 through Phase 2 clinical trials and exploring potential partnerships.
Summary
MAIA Biotechnology is a high-risk, high-reward clinical-stage biopharmaceutical company. Its strength lies in its innovative technology and targeted therapy approach, but it faces challenges related to funding, clinical trial success, and competition. Positive clinical trial results for THIO-101 are critical for its future growth. Investors need to be fully aware of the risks associated with investing in developmental therapeutics. They must also lookout for cashflow and the ability for the company to stay in business.
Peer Comparison
Sources and Disclaimers
Data Sources:
- Company website
- SEC filings
- Analyst reports (where available)
- ClinicalTrials.gov
Disclaimers:
The information provided is for informational purposes only and should not be considered investment advice. Investing in biopharmaceutical companies is inherently risky, and investors should conduct their own due diligence before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About MAIA Biotechnology Inc.
Exchange NYSE MKT | Headquaters Chicago, IL, United States | ||
IPO Launch date 2022-07-28 | Co-Founder, President, CEO & Chairman of the Board of Directors Dr. Vlad Vitoc M.B.A., M.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 13 | Website https://maiabiotech.com |
Full time employees 13 | Website https://maiabiotech.com |
MAIA Biotechnology, Inc., together with its subsidiaries, immuno-oncology company, focuses on the development and commercialization of drugs with novel mechanisms of action that are intended to improve and extend the lives of people with cancer. Its lead program is THIO, a potential cancer telomere targeting agent in clinical development for the treatment of NSCLC patients with telomerase-positive cancer cells. The company was incorporated in 2018 and is headquartered in Chicago, Illinois.

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