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Mediwound Ltd (MDWD)

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Upturn Advisory Summary
12/02/2025: MDWD (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $31.5
1 Year Target Price $31.5
| 4 | Strong Buy |
| 2 | Buy |
| 0 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -38.98% | Avg. Invested days 26 | Today’s Advisory PASS |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 220.66M USD | Price to earnings Ratio - | 1Y Target Price 31.5 |
Price to earnings Ratio - | 1Y Target Price 31.5 | ||
Volume (30-day avg) 6 | Beta 0.07 | 52 Weeks Range 14.14 - 22.50 | Updated Date 12/2/2025 |
52 Weeks Range 14.14 - 22.50 | Updated Date 12/2/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -1.84 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Geography
Earnings Date
Report Date 2025-11-20 | When - | Estimate -0.8133 | Actual -0.24 |
Profitability
Profit Margin -98.43% | Operating Margin (TTM) -120.19% |
Management Effectiveness
Return on Assets (TTM) -17.42% | Return on Equity (TTM) -48.83% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 169196790 | Price to Sales(TTM) 10.54 |
Enterprise Value 169196790 | Price to Sales(TTM) 10.54 | ||
Enterprise Value to Revenue 8.08 | Enterprise Value to EBITDA -6.32 | Shares Outstanding 12821433 | Shares Floating 9715825 |
Shares Outstanding 12821433 | Shares Floating 9715825 | ||
Percent Insiders 15.14 | Percent Institutions 53.72 |
Upturn AI SWOT
Mediwound Ltd

Company Overview
History and Background
MediWound Ltd. was founded in 2000. It is a biopharmaceutical company focused on developing, manufacturing, and commercializing novel, cost-effective, bio-therapeutic solutions for severe burns, chronic wounds, and other hard-to-treat wound care indications.
Core Business Areas
- NexoBrid: Development and commercialization of NexoBrid, a topical enzymatic debridement product for the removal of dead or damaged tissue in severe burns.
- EscharEx: Development of EscharEx, a topical enzymatic debridement product for the treatment of chronic wounds.
Leadership and Structure
The leadership team includes the CEO, CFO, and other key executives. The company operates with a functional organizational structure.
Top Products and Market Share
Key Offerings
- NexoBrid: NexoBrid is the lead product, an enzymatic debridement agent used for removing eschar in burn patients. It aims to reduce or eliminate the need for surgical debridement. Market share data varies by region, but it is growing in Europe. Competitors include traditional surgical debridement, Versajet hydrosurgery system (Smith & Nephew).
- EscharEx: EscharEx is a product in development for chronic wound debridement. No significant revenue or market share yet. Competitors would include Santyl (collagenase ointment) from Smith+Nephew, enzymatic debridement products, and sharp debridement.
Market Dynamics
Industry Overview
The wound care market is growing due to factors such as an aging population, rising incidence of diabetes and obesity, and increasing prevalence of chronic wounds. There is demand for advanced wound care products.
Positioning
MediWound positions itself as a leader in enzymatic debridement, offering a non-surgical alternative. They aim to provide faster and more effective wound healing.
Total Addressable Market (TAM)
The global wound care market is expected to reach over $22 billion by 2027. MediWound is focused on specific segments within this large TAM, such as burn care and chronic wound care. The company's positioning in enzymatic debridement allows them to capture market share in the debridement category.
Upturn SWOT Analysis
Strengths
- Novel enzymatic debridement technology
- Clinical data supporting efficacy of NexoBrid
- Established partnerships for commercialization
- Experienced management team
Weaknesses
- Reliance on a limited number of products
- Dependence on partners for distribution
- Regulatory and reimbursement risks
- Relatively small company size
- Cash burn rate/lack of profitability
Opportunities
- Expansion into new geographic markets
- Development of new indications for existing products
- Partnerships with other healthcare companies
- Acquisition of complementary technologies
Threats
- Competition from established wound care companies
- Failure to obtain regulatory approvals
- Unfavorable reimbursement policies
- Product liability claims
Competitors and Market Share
Key Competitors
- Smith & Nephew (SNN)
- Integra LifeSciences (IART)
- Organogenesis Holdings (ORGO)
Competitive Landscape
MediWound competes with larger, more established wound care companies. Its advantage lies in its novel enzymatic debridement technology. Disadvantages include its smaller size and limited resources.
Major Acquisitions
None
- Year: 2024
- Acquisition Price (USD millions): 0
- Strategic Rationale: N/A
Growth Trajectory and Initiatives
Historical Growth: MediWound's growth has been driven primarily by the commercialization of NexoBrid. Sales have grown over time as it gains market acceptance and expands into new markets.
Future Projections: Analyst estimates project continued revenue growth, driven by increased sales of NexoBrid and potential launch of EscharEx. Profitability is expected to improve.
Recent Initiatives: Recent initiatives include expanding commercial partnerships, conducting clinical trials for new indications, and developing new products.
Summary
MediWound is a biopharmaceutical company with a novel enzymatic debridement technology, particularly NexoBrid, which has shown promise in burn treatment. The company's strengths lie in its innovative technology and clinical data, but its weaknesses include its small size and dependence on partnerships. Future success depends on expanding market reach, securing regulatory approvals, and maintaining a competitive advantage. While the company has strong technology, profitability remains a challenge.
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Sources and Disclaimers
Data Sources:
- Company website
- Investor presentations
- Analyst reports
- SEC filings
Disclaimers:
This analysis is for informational purposes only and does not constitute financial advice. Market data and analyst estimates are subject to change.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Mediwound Ltd
Exchange NASDAQ | Headquaters - | ||
IPO Launch date 2014-03-20 | CEO - | ||
Sector Healthcare | Industry Biotechnology | Full time employees 111 | Website https://www.mediwound.com |
Full time employees 111 | Website https://www.mediwound.com | ||
MediWound Ltd., a biopharmaceutical company, develops, manufactures, and commercializes novel, bio-therapeutic, and non-surgical solutions for tissue repair and regeneration in the United States and internationally. It markets NexoBrid, a biopharmaceutical product for the removal of eschar, a dead or damaged tissue in patients with deep partial- and full-thickness thermal burns to burn centers and hospitals burn units. The company also develops EscharEx for the treatment of chronic wounds and other hard-to-heal wounds; and MW005, a topically applied biological product candidate to treat non-melanoma skin cancers. MediWound Ltd. was incorporated in 2000 and is headquartered in Yavne, Israel.

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