Upturn unsubscribed user
$1.14/ day, billed weekly
Cancel anytime
(Ad-Free, Unlimited access)​
NO CREDIT CARD REQUIRED
MIST logo MIST
Upturn stock ratingUpturn stock rating
MIST logo

Milestone Pharmaceuticals Inc (MIST)

Upturn stock ratingUpturn stock rating
$1.94
Last Close (24-hour delay)
Profit since last BUY22.01%
upturn advisory
Consider higher Upturn Star rating
BUY since 22 days
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK

Upturn Advisory Summary

06/30/2025: MIST (1-star) has a low Upturn Star Rating. Not recommended to BUY.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

4 Analysts rated it

Limited analyst coverage, niche firm, research info may be scarce.

1 Year Target Price $3.33

1 Year Target Price $3.33

Analysts Price Target For last 52 week
$3.33Target price
Low$0.62
Current$1.94
high$2.75

Analysis of Past Performance

Type Stock
Historic Profit -64.68%
Avg. Invested days 19
Today’s Advisory Consider higher Upturn Star rating
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 1.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 06/30/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 99.44M USD
Price to earnings Ratio -
1Y Target Price 3.33
Price to earnings Ratio -
1Y Target Price 3.33
Volume (30-day avg) 4
Beta 0.92
52 Weeks Range 0.62 - 2.75
Updated Date 06/30/2025
52 Weeks Range 0.62 - 2.75
Updated Date 06/30/2025
Dividends yield (FY) -
Basic EPS (TTM) -0.77

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -41.29%
Return on Equity (TTM) -307.27%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 99072547
Price to Sales(TTM) 77.32
Enterprise Value 99072547
Price to Sales(TTM) 77.32
Enterprise Value to Revenue 81.44
Enterprise Value to EBITDA -1.43
Shares Outstanding 53464300
Shares Floating 50946026
Shares Outstanding 53464300
Shares Floating 50946026
Percent Insiders 4.71
Percent Institutions 22.25

Analyst Ratings

Rating 2
Target Price 3.33
Buy 2
Strong Buy -
Buy 2
Strong Buy -
Hold 2
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Milestone Pharmaceuticals Inc

stock logo

Company Overview

overview logo History and Background

Milestone Pharmaceuticals Inc. (formerly known as Microdermics Inc.) was founded in 2003. The company focuses on developing and commercializing innovative pharmaceutical products for cardiovascular diseases. Milestone's lead product candidate is etripamil, a novel calcium channel blocker nasal spray.

business area logo Core Business Areas

  • Cardiovascular Therapeutics: Focuses on developing and commercializing Etripamil nasal spray for the treatment of paroxysmal supraventricular tachycardia (PSVT).

leadership logo Leadership and Structure

Milestone Pharmaceuticals Inc. is led by a management team with experience in the pharmaceutical industry. The company has a board of directors that provides oversight and guidance.

Top Products and Market Share

overview logo Key Offerings

  • Etripamil Nasal Spray: Etripamil is a novel calcium channel blocker nasal spray being developed for the acute treatment of paroxysmal supraventricular tachycardia (PSVT). Milestone Pharmaceuticals has been awaiting FDA approval. The current standard of care includes adenosine and vagal maneuvers. Competitors include companies that manufacture Adenosine, and develop and market antiarrhythmic drugs.

Market Dynamics

industry overview logo Industry Overview

The cardiovascular therapeutics market is large and growing, driven by an aging population and increasing prevalence of cardiovascular diseases. There is a need for new and improved treatments for conditions like PSVT.

Positioning

Milestone Pharmaceuticals aims to position etripamil as a convenient and effective alternative to existing treatments for PSVT, such as intravenous adenosine. The ease of administration as a nasal spray gives it a competitive advantage.

Total Addressable Market (TAM)

The estimated TAM for PSVT treatments is significant, potentially reaching hundreds of millions of dollars annually. Milestone's positioning revolves around capturing a substantial share of this market with its unique nasal spray formulation. Exact figures are difficult to determine without market approval.

Upturn SWOT Analysis

Strengths

  • Novel delivery method (nasal spray)
  • Potential for rapid onset of action
  • Potential to reduce reliance on intravenous treatments
  • Addresses a specific unmet need in PSVT treatment

Weaknesses

  • Single product focus (Etripamil)
  • Regulatory approval risk (FDA)
  • Commercialization risk (market penetration)
  • Relatively small company size

Opportunities

  • Expansion of etripamil into other indications
  • Partnerships with larger pharmaceutical companies
  • Geographic expansion into new markets
  • Acquisition of other cardiovascular assets

Threats

  • Competition from existing PSVT treatments
  • Failure to obtain regulatory approval
  • Adverse clinical trial results
  • Changes in reimbursement policies

Competitors and Market Share

competitor logo Key Competitors

  • HLX
  • TAK
  • MRK
  • PFE

Competitive Landscape

Milestone's key advantage lies in its novel nasal spray formulation. However, it faces competition from established companies with existing PSVT treatments and greater resources.

Growth Trajectory and Initiatives

Historical Growth: Historical growth has been driven by clinical trial progress and fundraising activities.

Future Projections: Future growth is heavily dependent on FDA approval of etripamil and successful commercialization. Analyst estimates vary depending on the likelihood of approval and market penetration.

Recent Initiatives: Recent initiatives include completing clinical trials, preparing for regulatory submission, and exploring potential commercialization strategies.

Summary

Milestone Pharmaceuticals is a development-stage company focused on Etripamil, a novel nasal spray for PSVT. Its success hinges on FDA approval and effective commercialization. The company's innovative delivery method could provide a competitive edge. Risks include regulatory hurdles and competition from established players.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • SEC Filings (10-K, 10-Q), Company Website, Press Releases, Analyst Reports

Disclaimers:

This analysis is for informational purposes only and does not constitute financial advice. Investment decisions should be made based on your own research and due diligence.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Milestone Pharmaceuticals Inc

Exchange NASDAQ
Headquaters Montreal, QC, Canada
IPO Launch date 2019-05-09
CEO, President & Director Mr. Joseph G. Oliveto M.B.A.
Sector Healthcare
Industry Biotechnology
Full time employees 33
Full time employees 33

Milestone Pharmaceuticals Inc., a biopharmaceutical company, focuses on the development and commercialization of cardiovascular medicines in the United States and Canada. The company's lead product candidate is etripamil, a novel and potent calcium channel blocker, which has completed phase III clinical trial for the treatment of paroxysmal supraventricular tachycardia; and Phase II clinical trial for the treatment of atrial fibrillation and rapid ventricular rate. It has a license and collaboration agreement with Corxel Pharmaceuticals to develop and commercialize etripamil. Milestone Pharmaceuticals Inc.was incorporated in 2003 and is headquartered in Montreal, Canada.