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MoonLake Immunotherapeutics (MLTX)



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Upturn Advisory Summary
09/17/2025: MLTX (1-star) is a SELL. SELL since 1 days. Simulated Profits (22.15%). Updated daily EoD!
1 Year Target Price $76.36
1 Year Target Price $76.36
12 | Strong Buy |
4 | Buy |
0 | Hold |
0 | Sell |
0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit 74.66% | Avg. Invested days 46 | Today’s Advisory SELL |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Mid-Cap Stock | Market Capitalization 3.38B USD | Price to earnings Ratio - | 1Y Target Price 76.36 |
Price to earnings Ratio - | 1Y Target Price 76.36 | ||
Volume (30-day avg) 16 | Beta 1.27 | 52 Weeks Range 31.42 - 61.87 | Updated Date 09/17/2025 |
52 Weeks Range 31.42 - 61.87 | Updated Date 09/17/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -2.79 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -24.99% | Return on Equity (TTM) -40.34% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 3032768670 | Price to Sales(TTM) - |
Enterprise Value 3032768670 | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA -41.53 | Shares Outstanding 63501400 | Shares Floating 24060046 |
Shares Outstanding 63501400 | Shares Floating 24060046 | ||
Percent Insiders 15.41 | Percent Institutions 94.84 |
Upturn AI SWOT
MoonLake Immunotherapeutics

Company Overview
History and Background
MoonLake Immunotherapeutics was founded in 2021 and is focused on developing and commercializing innovative therapies for immune-mediated inflammatory diseases. The company licensed Sonelokimab from Merck KGaA in 2021 and went public in 2022.
Core Business Areas
- Clinical Development: Focuses on the clinical development of Sonelokimab for various indications.
- Research and Development: Discovery and development of novel therapies for immune-mediated inflammatory diseases.
- Commercialization: Planning and execution of commercialization strategies for approved products.
Leadership and Structure
Dr. Jorge Santos Da Silva is the Chief Executive Officer. The company has a board of directors and a management team focused on clinical development and commercialization.
Top Products and Market Share
Key Offerings
- Sonelokimab: An investigational Nanobodyu00ae targeting IL-17A and IL-17F, under development for the treatment of hidradenitis suppurativa (HS), psoriasis, and psoriatic arthritis (PsA). It is still under clinical trials with no current market share or revenue. Competitors in this space include AbbVie (Humira, Skyrizi), Novartis (Cosentyx), and Eli Lilly (Taltz).
Market Dynamics
Industry Overview
The market for immune-mediated inflammatory disease therapies is large and growing, driven by increasing prevalence and unmet medical needs.
Positioning
MoonLake is positioned as a leader in IL-17A/F inhibition, targeting a broad range of inflammatory diseases. Its competitive advantage lies in Sonelokimab's potential best-in-class efficacy.
Total Addressable Market (TAM)
The TAM for IL-17 inhibitors in indications like HS, psoriasis, and PsA is estimated to be in the billions of dollars annually. MoonLake is positioned to capture a significant share of this market if Sonelokimab receives regulatory approval.
Upturn SWOT Analysis
Strengths
- Novel IL-17A/F Nanobodyu00ae with potential for superior efficacy
- Experienced management team
- Strong clinical trial results (early stage)
- Focused on large and growing market segments
Weaknesses
- Single product focus (Sonelokimab)
- No approved products and dependent on clinical trial success
- Reliance on funding for clinical development
- Relatively new company with limited commercial experience
Opportunities
- Expansion of Sonelokimab into additional indications
- Potential for partnerships and collaborations
- Positive clinical trial results driving market value
- Acquisition by a larger pharmaceutical company
Threats
- Clinical trial failures
- Regulatory hurdles
- Competition from established players
- Patent challenges
- Generic erosion post approval of new products
Competitors and Market Share
Key Competitors
- ABBV
- NVS
- LLY
Competitive Landscape
MoonLake faces competition from established pharmaceutical companies with marketed products for immune-mediated inflammatory diseases. Its competitive advantage hinges on the potential for Sonelokimab to offer superior efficacy and convenience.
Growth Trajectory and Initiatives
Historical Growth: Historical growth is primarily reflected in increasing R&D spending and expansion of clinical programs.
Future Projections: Future growth is dependent on the successful development and commercialization of Sonelokimab. Analyst estimates vary based on clinical trial outcomes and market penetration assumptions.
Recent Initiatives: Advancement of Sonelokimab through Phase 2 and Phase 3 clinical trials, and exploration of new indications.
Summary
MoonLake Immunotherapeutics is a clinical-stage biopharmaceutical company with a promising lead product candidate, Sonelokimab, targeting IL-17A/F. The company is financially stable and continues to develop its novel therapy for multiple indications. Successful clinical trials and regulatory approvals are essential for its growth; it faces intense competition from established players. A key risk is clinical trial failure, which would heavily impact its future.
Peer Comparison
Sources and Disclaimers
Data Sources:
- MoonLake Immunotherapeutics Investor Relations
- Company SEC Filings
- Analyst Reports
- ClinicalTrials.gov
Disclaimers:
The information provided is for informational purposes only and should not be considered investment advice. Investment decisions should be made based on individual financial circumstances and after consulting with a qualified financial advisor. Market share data are estimates based on available information.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About MoonLake Immunotherapeutics
Exchange NASDAQ | Headquaters - | ||
IPO Launch date 2020-10-20 | Co-Founder, CEO & Director Dr. Jorge Santos da Silva Ph.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 100 | Website https://www.moonlaketx.com |
Full time employees 100 | Website https://www.moonlaketx.com |
MoonLake Immunotherapeutics, a clinical stage biotechnology company, focuses on developing therapies for inflammatory skin and joint diseases. It develops Sonelokimab, a novel tri-specific IL-17A and IL-17F inhibiting Nanobody for the treatment of inflammatory diseases, as well as for hidradenitis suppurativa, psoriatic arthritis, axial spondyloarthritis, palmoplantar pustulosis, and psoriasis. The company was founded in 2021 and is headquartered in Zug, Switzerland.

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