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Mersana Therapeutics Inc (MRSN)

Upturn stock ratingUpturn stock rating
$0.3
Last Close (24-hour delay)
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PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
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Upturn Advisory Summary

06/30/2025: MRSN (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

9 Analysts rated it

Moderately tracked stock, growing coverage, gaining market and investor attention.

1 Year Target Price $4.29

1 Year Target Price $4.29

Analysts Price Target For last 52 week
$4.29Target price
Low$0.26
Current$0.3
high$2.83

Analysis of Past Performance

Type Stock
Historic Profit 6.72%
Avg. Invested days 60
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 2.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 06/30/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 36.27M USD
Price to earnings Ratio -
1Y Target Price 4.29
Price to earnings Ratio -
1Y Target Price 4.29
Volume (30-day avg) 9
Beta 0.82
52 Weeks Range 0.26 - 2.83
Updated Date 06/30/2025
52 Weeks Range 0.26 - 2.83
Updated Date 06/30/2025
Dividends yield (FY) -
Basic EPS (TTM) -0.59

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -217.63%
Operating Margin (TTM) -890.05%

Management Effectiveness

Return on Assets (TTM) -30.9%
Return on Equity (TTM) -505.14%

Valuation

Trailing PE -
Forward PE -
Enterprise Value -41395281
Price to Sales(TTM) 1.07
Enterprise Value -41395281
Price to Sales(TTM) 1.07
Enterprise Value to Revenue 4.66
Enterprise Value to EBITDA -2.2
Shares Outstanding 124631000
Shares Floating 93834935
Shares Outstanding 124631000
Shares Floating 93834935
Percent Insiders 1.48
Percent Institutions 72.21

Analyst Ratings

Rating 3
Target Price 4.29
Buy -
Strong Buy 8
Buy -
Strong Buy 8
Hold 1
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Mersana Therapeutics Inc

stock logo

Company Overview

overview logo History and Background

Mersana Therapeutics Inc. was founded in 2001 and is a clinical-stage biopharmaceutical company focused on discovering and developing antibody-drug conjugates (ADCs) for cancer. It has evolved from a research-focused entity to a clinical-stage company with multiple programs.

business area logo Core Business Areas

  • ADC Platform Technology: Mersana focuses on developing ADCs using its Dolaflexin and Immunosynthen platforms. These platforms are designed to create ADCs with improved efficacy and safety profiles compared to traditional approaches.
  • Drug Development: Mersana is involved in the development and clinical testing of ADCs for various cancer types.
  • Partnerships and Licensing: Mersana has partnered with various pharmaceutical companies to license its technology and co-develop ADC therapeutics.

leadership logo Leadership and Structure

The leadership team consists of experienced professionals in the biopharmaceutical industry. The organizational structure is typical of a clinical-stage biotech, with departments dedicated to research, development, clinical trials, and business development. Anna Protopapas is the current CEO.

Top Products and Market Share

overview logo Key Offerings

  • Upifitamab Rilsodotin (UpRi): UpRi is Mersana's lead ADC candidate targeting NaPi2b-expressing tumors, including ovarian cancer. It's in clinical development. Market share data is not yet available as it is not approved. Key competitors are other companies developing therapies for NaPi2b expressing cancers, especially ADCs. These include companies targeting similar pathways or tumor types with different modalities, such as GSK's Blenrep.
  • XMT-1660: A Dolasynthen ADC targeting B7-H4 expressing tumors. It's in Phase 1 clinical trial. Market share data is not yet available as it is not approved. Key competitors are other companies developing therapies for B7-H4 expressing cancers, especially ADCs.

Market Dynamics

industry overview logo Industry Overview

The biopharmaceutical industry, particularly the oncology segment, is highly competitive and dynamic. There's significant investment in ADC development due to its potential for targeted cancer therapy.

Positioning

Mersana is positioned as an innovator in ADC technology with its novel platforms. Its competitive advantage lies in the potential of its platforms to create ADCs with improved efficacy, safety, and manufacturability.

Total Addressable Market (TAM)

The total addressable market (TAM) for ADC therapeutics is estimated to reach billions of dollars. Mersana is positioned to capture a portion of this TAM through its proprietary technology and partnerships. Estimates range from $10 billion to $20 billion by the late 2020s. The addressable market depends on the indication and penetration.

Upturn SWOT Analysis

Strengths

  • Innovative ADC platform technology
  • Experienced management team
  • Strong intellectual property position
  • Strategic partnerships with pharmaceutical companies

Weaknesses

  • Limited financial resources compared to larger pharmaceutical companies
  • Dependence on clinical trial outcomes
  • High attrition rate in drug development
  • Not yet profitable

Opportunities

  • Potential for significant revenue generation through successful drug development and commercialization
  • Expansion of ADC platform technology to new targets and indications
  • Further strategic partnerships and licensing agreements
  • Acquisition by a larger pharmaceutical company

Threats

  • Clinical trial failures
  • Competition from other ADC developers
  • Regulatory hurdles
  • Patent challenges

Competitors and Market Share

competitor logo Key Competitors

  • GSK
  • ImmunoGen (IMGN)
  • Seagen (SGEN)

Competitive Landscape

Mersana faces competition from other companies developing ADCs, including established pharmaceutical companies with greater resources. Its advantage lies in its unique ADC platforms.

Growth Trajectory and Initiatives

Historical Growth: Historical growth is characterized by R&D advancements and strategic partnerships, but not yet by product revenue.

Future Projections: Future growth is dependent on the successful clinical development and commercialization of its ADC candidates. Analyst estimates vary widely based on clinical trial outcomes.

Recent Initiatives: Recent initiatives include advancing UpRi and XMT-1660 through clinical trials and seeking new partnerships.

Summary

Mersana Therapeutics is a clinical-stage biopharmaceutical company focused on antibody-drug conjugates with innovative platforms. It is currently not profitable and relies on partnerships to fund clinical trials. Success hinges on clinical trial results; however, the innovative platform offers a unique selling point. Mersana needs to monitor competition and manage its cash burn rate.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Mersana Therapeutics Inc. SEC filings (10-K, 10-Q), company website, industry reports, analyst reports.

Disclaimers:

This analysis is based on publicly available information and is for informational purposes only. It is not financial advice. Actual results may vary.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Mersana Therapeutics Inc

Exchange NASDAQ
Headquaters Cambridge, MA, United States
IPO Launch date 2017-06-28
President, CEO & Director Dr. Martin H. Huber M.D.
Sector Healthcare
Industry Biotechnology
Full time employees 102
Full time employees 102

Mersana Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops antibody-drug conjugates (ADC) for cancer patients with unmet needs. The company develops Emi-Le (XMT-1660), a B7-H4-targeting Dolasynthen ADC candidate, which is in Phase 1 clinical trial; and XMT-2056, an Immunosynthen ADC targeting a novel human epidermal growth factor receptor 2 that is in Phase 1 clinical trial. Its preclinical products portfolio includes XMT-2068 and XMT-2175. It has strategic research and development collaborations with Janssen Biotech, Inc., Ares Trading S.A., Merck KGaA, and Asana Biosciences, LLC for the development of ADC product candidates. The company was formerly known as Nanopharma Corp. and changed its name to Mersana Therapeutics, Inc. in November 2005. Mersana Therapeutics, Inc. was incorporated in 2001 and is headquartered in Cambridge, Massachusetts.