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Upturn stock rating
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Mural Oncology plc (MURA)

Upturn stock rating
$2.09
Last Close (24-hour delay)
upturn advisory
PASS
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  • SELL Advisory (Loss)​
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Upturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
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  • WEEK

Upturn Advisory Summary

10/23/2025: MURA (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

4 Analysts rated it

Very few follow this stock; limited insights, higher-risk early investing.

1 Year Target Price $6

1 Year Target Price $6

Analysts Price Target For last 52 week
$6 Target price
52w Low $0.95
Current$2.09
52w High $4.74

Analysis of Past Performance

Type Stock
Historic Profit -41.86%
Avg. Invested days 29
Today’s Advisory PASS
Upturn Star Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance 1.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulation Last Close 10/23/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 36.21M USD
Price to earnings Ratio -
1Y Target Price 6
Price to earnings Ratio -
1Y Target Price 6
Volume (30-day avg) 4
Beta -
52 Weeks Range 0.95 - 4.74
Updated Date 10/24/2025
52 Weeks Range 0.95 - 4.74
Updated Date 10/24/2025
Dividends yield (FY) -
Basic EPS (TTM) -8.58

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -52.6%
Return on Equity (TTM) -111.75%

Valuation

Trailing PE -
Forward PE -
Enterprise Value -36058725
Price to Sales(TTM) -
Enterprise Value -36058725
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -
Shares Outstanding 17324771
Shares Floating 12125839
Shares Outstanding 17324771
Shares Floating 12125839
Percent Insiders 13.49
Percent Institutions 57.98

ai summary icon Upturn AI SWOT

Mural Oncology plc

stock logo

Company Overview

overview logo History and Background

Mural Oncology plc is a clinical-stage biopharmaceutical company focused on developing novel immunotherapies for cancer. While information on its precise founding year and detailed early milestones is limited, it has emerged as a player in the targeted oncology space.

business area logo Core Business Areas

  • Cell Therapy: Development of cell therapies targeting solid tumors. This includes research, development, and clinical trials for novel cellular therapies.
  • Antibody Development: Development of new antibody therapeutics to target cancer cells and modulate the immune system.

leadership logo Leadership and Structure

Details on specific leadership team members and organizational structure were not found during research. As a public company, such information is generally available on the investor relations section of their website or in regulatory filings.

Top Products and Market Share

overview logo Key Offerings

  • Lead Cell Therapy Candidate (name unknown): Mural Oncology's lead cell therapy candidate is currently in clinical development targeting a specific set of solid tumors. No specific market share data or revenue figures are publicly available. Competitors include companies developing cell therapies for solid tumors, such as Adaptimmune Therapeutics (ADAP) and Iovance Biotherapeutics (IOVA).
  • Antibody Candidates (names unknown): Mural Oncology has a pipeline of antibody candidates also in clinical trials. No revenue figures exist, and no market share is assigned to these candidates at this pre-commercial stage. Competitors are numerous and depend on the specific antibody target but include companies developing similar antibody therapeutics, such as Regeneron (REGN) and Bristol Myers Squibb (BMY).

Market Dynamics

industry overview logo Industry Overview

The oncology therapeutics market is a large and rapidly growing market, driven by an aging population, increasing cancer incidence rates, and advances in cancer research. Immunotherapies, including cell therapies and antibody-based therapies, are a significant growth area.

Positioning

Mural Oncology is positioned as a developer of novel immunotherapies for solid tumors, focusing on cell therapy and antibody-based approaches. Their competitive advantage, if any, would reside in the uniqueness and efficacy of their specific therapeutic candidates.

Total Addressable Market (TAM)

The global oncology market is estimated at several hundred billion USD annually. Mural Oncology's TAM depends on the specific cancer types their therapies target. If they were targeting a rare cancer, it is substantially smaller than targeting a more common type such as lung cancer.

Upturn SWOT Analysis

Strengths

  • Novel immunotherapy pipeline
  • Experienced scientific team
  • Strong focus on solid tumors

Weaknesses

  • Early-stage clinical development
  • High cash burn rate
  • Dependence on clinical trial success
  • Limited brand recognition

Opportunities

  • Positive clinical trial results
  • Partnerships with larger pharmaceutical companies
  • Expansion of product pipeline
  • Acquisition by a larger company

Threats

  • Clinical trial failures
  • Regulatory hurdles
  • Competition from established pharmaceutical companies
  • Changes in healthcare reimbursement policies

Competitors and Market Share

competitor logo Key Competitors

  • ADAP
  • IOVA
  • BMY
  • REGN

Competitive Landscape

Mural Oncology faces significant competition from larger, established pharmaceutical companies with greater resources and more advanced pipelines. Mural Oncology needs to generate successful clinical trial data to become a competitive player in this market.

Growth Trajectory and Initiatives

Historical Growth: Historical growth is limited due to its stage of development.

Future Projections: Future growth projections depend heavily on the success of its clinical trials and regulatory approvals. Analyst estimates, if any, would be based on these factors.

Recent Initiatives: Recent initiatives would likely focus on advancing its clinical trials and securing partnerships.

Summary

Mural Oncology is a clinical-stage biotech company with potential in solid tumor immunotherapies, but it's currently high-risk due to its dependence on clinical trial success. Its novel pipeline presents opportunities, but competition is fierce, and financial stability is critical. Positive clinical data will be essential for its future trajectory and valuation. The company will need partnerships to survive in the long run.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company website (if available)
  • SEC filings (if available)
  • Third-party financial data providers (Yahoo Finance, Google Finance)
  • Industry reports and analyst estimates

Disclaimers:

The information provided is for informational purposes only and should not be considered financial advice. Investment decisions should be based on individual research and consultation with a qualified financial advisor. The data presented is based on publicly available information and may be subject to change.

Upturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Mural Oncology plc

Exchange NASDAQ
Headquaters -
IPO Launch date 2023-11-16
President, CEO & Director Ms. Caroline J. Loew Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 116
Full time employees 116

Mural Oncology plc operates as a clinical-stage oncology company that focuses on discovering and developing immunotherapies for the treatment of patients with cancer. The company's lead product candidate includes nemvaleukin alfa for the treatment of mucosal melanoma as a monotherapy and platinum-resistant ovarian cancer in combination with pembrolizumab. It also develops nemvaleukin to treat cutaneous melanoma and advanced solid tumors. The company also develops engineered interleukin-18 and tumor-targeted interleukin-12 programs. Mural Oncology plc was incorporated in 2017 and is based in Dublin, Ireland.