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NLSP
Upturn stock ratingUpturn stock rating

NLS Pharmaceutics AG (NLSP)

Upturn stock ratingUpturn stock rating
$2.9
Last Close (24-hour delay)
Profit since last BUY75.76%
upturn advisory
Consider higher Upturn Star rating
BUY since 36 days
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
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Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
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Time period over
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Upturn Advisory Summary

06/30/2025: NLSP (1-star) has a low Upturn Star Rating. Not recommended to BUY.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

1 Analysts rated it

Very few follow this stock; limited insights, higher-risk early investing.

1 Year Target Price $6

1 Year Target Price $6

Analysts Price Target For last 52 week
$6Target price
Low$1.3
Current$2.9
high$10.14

Analysis of Past Performance

Type Stock
Historic Profit -12.85%
Avg. Invested days 29
Today’s Advisory Consider higher Upturn Star rating
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 06/30/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 13.69M USD
Price to earnings Ratio -
1Y Target Price 6
Price to earnings Ratio -
1Y Target Price 6
Volume (30-day avg) 1
Beta 0.04
52 Weeks Range 1.30 - 10.14
Updated Date 06/29/2025
52 Weeks Range 1.30 - 10.14
Updated Date 06/29/2025
Dividends yield (FY) -
Basic EPS (TTM) -2.63

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -111.41%
Return on Equity (TTM) -862.92%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 14854260
Price to Sales(TTM) -
Enterprise Value 14854260
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -3.02
Shares Outstanding 4908030
Shares Floating 1687887
Shares Outstanding 4908030
Shares Floating 1687887
Percent Insiders 32.46
Percent Institutions 10.04

Analyst Ratings

Rating 1
Target Price 6
Buy -
Strong Buy -
Buy -
Strong Buy -
Hold 1
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

NLS Pharmaceutics AG

stock logo

Company Overview

overview logo History and Background

NLS Pharmaceutics AG is a Swiss biopharmaceutical company focused on the discovery and development of innovative therapies for patients with rare and complex central nervous system (CNS) disorders. Founded in 2015, NLS is dedicated to addressing unmet medical needs and improving the lives of individuals affected by these conditions.

business area logo Core Business Areas

  • Central Nervous System Disorders: NLS Pharmaceutics focuses on developing treatments for rare and complex CNS disorders, including narcolepsy, idiopathic hypersomnia (IHS) and attention deficit hyperactivity disorder (ADHD).

leadership logo Leadership and Structure

Alex Zwyer is the Chief Executive Officer. The organizational structure includes departments focused on research and development, clinical trials, and commercialization.

Top Products and Market Share

overview logo Key Offerings

  • Mazindol CR: Mazindol CR is a product that NLS has licensed from the Swiss Company, A.P.A. AG, and is developing for ADHD. The company plans to initiate a Phase 2 trial. Market share data is not yet available, but current competitors are Teva Pharmaceuticals (TEVA) and Tris Pharma.
  • Quilienceu00ae: Quilience (mazindol ER) is a product being developed for the treatment of narcolepsy. The company plans to initiate a Phase 3 trial. Market share data is not yet available, but current competitors are Jazz Pharmaceuticals (Jazz), Avadel Pharmaceuticals (AVDL), and Harmony Biosciences (HRMY).

Market Dynamics

industry overview logo Industry Overview

The biopharmaceutical industry is characterized by high R&D costs, regulatory scrutiny, and long development timelines. There is a growing demand for innovative therapies for CNS disorders.

Positioning

NLS Pharmaceutics is positioned as a company specializing in treatments for rare and complex CNS disorders with a focus on developing novel therapies. Its advantage is its focus on unmet needs and a commitment to innovation.

Total Addressable Market (TAM)

The total addressable market for narcolepsy and ADHD is substantial. Analysts estimate the narcolepsy market to reach billions of dollars in coming years, while the ADHD market is already a multi-billion dollar market. NLS Pharmaceutics aims to capture a portion of these markets with its novel therapies.

Upturn SWOT Analysis

Strengths

  • Specialized focus on CNS disorders
  • Novel therapy development
  • Experienced management team

Weaknesses

  • Limited financial resources
  • Early-stage development pipeline
  • High reliance on clinical trial outcomes

Opportunities

  • Partnerships and collaborations
  • Successful clinical trial results
  • Expansion into new markets

Threats

  • Regulatory hurdles
  • Competition from established pharmaceutical companies
  • Clinical trial failures
  • Funding risks

Competitors and Market Share

competitor logo Key Competitors

  • JAZZ
  • AVDL
  • HRMY
  • TEVA

Competitive Landscape

NLS Pharmaceutics faces competition from established pharmaceutical companies with greater resources and broader product portfolios. However, its focus on specific CNS disorders provides a niche advantage.

Growth Trajectory and Initiatives

Historical Growth: Historical growth trends are limited due to the company's early stage.

Future Projections: Future growth depends on the success of clinical trials and regulatory approvals of its product candidates.

Recent Initiatives: Recent initiatives include advancing clinical trials and seeking partnerships to support development and commercialization.

Summary

NLS Pharmaceutics is a development-stage company focusing on innovative therapies for CNS disorders. The company's success depends on positive clinical trial results, regulatory approvals, and successful commercialization. Limited financial resources and competition from established players pose challenges. The company has a niche advantage due to its focus on underserved areas. The company's early stage warrants cautious investment.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company website
  • SEC filings
  • Analyst reports
  • Third-party market research

Disclaimers:

The information provided is for informational purposes only and does not constitute financial advice. Investment decisions should be based on thorough research and consultation with a financial professional. Market share data is based on estimations and may vary. All data is as of the current date and subject to change.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About NLS Pharmaceutics AG

Exchange NASDAQ
Headquaters -
IPO Launch date 2021-01-29
Co-Founder, CEO & Director Mr. Alexander Zwyer M.B.A.
Sector Healthcare
Industry Biotechnology
Full time employees -
Full time employees -

NLS Pharmaceutics AG, a clinical-stage biopharmaceutical company, engages in the discovery and development of therapies for patients with rare and complex central nervous system disorders. The company is focusing on the development of treatments for narcolepsy, idiopathic hypersomnia, and other rare sleep disorders, as well as neurodevelopmental disorders, such as attention deficit hyperactivity disorder (ADHD). Its lead product candidates include Quilience for the treatment of narcolepsy; and Nolazol for the treatment of ADHD. The company also develops NLS-4, a selective dopamine reuptake inhibitor treatment for the chronic fatigue associated with the symptoms of Long-COVID; NLS-3, a repurposed reverse ester of methylphenidate for treatment of ADHD; NLS-8, a melatonin ML1A receptor agonist for improved scopolamine-induced amnesia; NLS-11, a norepinephrine and dopamine reuptake inhibitor and muscarinic M1, M2, M3 receptor antagonist; and NLS-12, a norepinephrine and dopamine reuptake inhibitor and muscarinic M4 receptor antagonist. It has licensing agreements with Pegasus Advanced Research for use of mazindol for the treatment of ADHD. NLS Pharmaceutics AG was incorporated in 2015 and is headquartered in Zurich, Switzerland.