Neumora Therapeutics, Inc. logo

Neumora Therapeutics, Inc.(NMRA)

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EXPLORE ADVISORIES AND THEIR HISTORY
QUALITY SIGNAL
1-STAR RATING
PASS
LAST CLOSE
$0.47
11/11/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
  • ALL
  • 1Y
  • 1M
  • 1W
  • BUY Advisory
  • SELL Advisory (Profit)
  • SELL Advisory (Loss)
  • Profit
  • Loss
  • PASS (Skip)
Upturn Stock price based on last close iconStock price based on last close
Simulated performance—not actual client returns. Excludes advisory subscription fees, trading commissions, and taxes, which would reduce returns. Results depend on calculation assumptions and do not guarantee future outcomes. See Disclosures for full methodology, assumptions, and limitations.

Advisory Performance History (Simulated)Advisory Performance History info

Simulated performance—not actual client returns. Excludes advisory subscription fees, trading commissions, and taxes, which would reduce returns. Results depend on calculation assumptions and do not guarantee future outcomes. See Disclosures for full methodology, assumptions, and limitations.

Upturn Advisory & Investor View for NMRA

11/11/2026: NMRA (1-star) is currently NOT-A-BUY. Pass it for now.

Neumora Therapeutics is a clinical-stage biotechnology company that aims to innovate in neuroscience by utilizing a precision medicine platform. Its primary investment story centers on the potential of its pipeline, including Navacaprant for depression, to address significant unmet medical needs. While the company benefits from strategic partnerships and a robust R&D approach, it faces substantial risks, including the high failure rate of clinical trials and the need for future capital. The stock is best suited for growth-oriented investors who can tolerate high volatility and extended timelines. Investors should closely monitor clinical trial milestones and regulatory developments that are essential for long-term viability.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorMixed fitThe company offers high growth potential linked to binary clinical trial outcomes rather than established revenue growth.
Momentum investorMixed fitMomentum is highly sensitive to news flow regarding clinical trial data and regulatory updates.
Value investorWeak fitTraditional value metrics like P/E are not applicable as the company is not profitable.
Dividend investorWeak fitThe company does not pay dividends and focuses entirely on reinvestment.
Low-risk investorWeak fitHigh volatility and clinical/regulatory risks make this unsuitable for low-risk portfolios.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighClinical-stage biotech stocks often experience sharp price swings based on trial results.
Valuation riskMedium / highValuations are speculative and highly dependent on long-term project success.
Competition risk (Neuroscience drug development)HighNumerous well-capitalized firms are pursuing similar patient populations.
Business qualityMediumThe company has strong scientific backing but lacks a track record of commercialization.
Dividend incomeLow / noneThe company provides no income to shareholders.
Execution riskHighSuccessfully managing large-scale clinical trials and navigating the FDA approval process is extremely difficult.

Price Behavior

Steep Decline
PRICE PATH

Steep Decline

The stock price has dropped sharply with strong downward pressure.

Extreme Price Shocks
PRICE STABILITY

Extreme Price Shocks

The stock has experienced exceptionally large and disruptive price movements during the period.

Analysis of Past Performance

Type Stock
Historic Profit -25.31%
Avg. Invested days 19
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 2.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 11/11/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
NMRA receives a 2-star rating, supported by solid analyst coverage. The rating is constrained by weak unit economics, soft quantitative characteristics, and weak price momentum.

Company Fundamentals

★★★★★
NMRA has moderate overall fundamentals (3 stars), with moderate financial health, moderate growth momentum, and solid ownership. In FY2025 versus FY2024, moderate earnings growth (+2.8%) is partially offset by soft cash generation (FCF margin 0.0%), slightly negative revenue growth (+0.0%), soft profitability (net margin 0.0%).

Financial Health Rating

★★★★★
NMRA's financial health is supported by strong efficiency, including operating-expense and cost-of-revenue discipline (opex 0.0% of revenue). Profitability is weak (1 stars), which helps explain the 3-star overall score.

Growth Momentum Score

★★★★★
Earnings growth is NMRA's strongest growth driver at +2.8% FY2025 versus FY2024 (moderate, 3 stars). By comparison, while revenue growth (+0.0%, slightly negative) and free-cash-flow growth (-12.8%, negative) hold the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 59.9% and approximately 62.0% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 23.08% supports management-shareholder alignment.

Top 5 Institutional Investors

Siren, L.L.C. 4.52%
BlackRock Inc 4.15%
SoftBank Group Corp 3.24%
Vanguard Capital Management, LLC 2.49%
MIC Capital Management UK LLP 2.37%

Unit Economics (Per $1K Revenue)

★★★★★
NMRA generates approximately $-0 of gross profit, $-0 of operating income, and $-0 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Weak margins explain the 1-star rating, with weak cash conversion and weak capital efficiency.

Economic Dimensions

★★★★★
Effective Tax Rate: -0.05% (Tax Credit)

Quantitative Style Profile

★★★★★
NMRA has a liquid profile. Weak momentum is the primary drawback, while elevated volatility.

Style Classification

Quality Focused

High VolatilitySmall / Mid Cap RiskShort Squeeze RiskHighly Liquid / Institution-Friendly

Sector & Industry Intelligence

Sector snapshot as of 2026-11-10

Sector

Healthcare

Signal
Constructive
Sentiment
Strong Bullish
Market state
Strong Bullish
Momentum
BUY Breadth Improving
BUY participation
60.0%
Active BUY / eligible
69 / 115
22-session BUY-count change
+29

More qualifying stocks are receiving or maintaining BUY advisories, indicating improving market participation.

Industry

Biotechnology

BUY participation
43.5%
Active BUY / eligible
20 / 46
22-session BUY-count change
+12

The sector signal does not change this stock’s BUY, SELL, or PASS advisory.

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 87.67M USD
Price to earnings Ratio -
1Y Target Price 6.5
Price to earnings Ratio -
1Y Target Price 6.5
Volume (30-day avg) 2.0M shares
Beta 3.14
52 Weeks Range 0.32 - 3.65
Updated Date 11/10/2026
52 Weeks Range 0.32 - 3.65
Updated Date 11/10/2026
Dividends yield (FY) -
Basic EPS (TTM) -1.23

How Company Makes Money

Business areaWhat it includesRetail investor read
Research and Development / LicensingPotential future milestone payments, royalties, and commercial revenue from licensed or owned therapies.The company currently makes no money; it is betting on the success of its drug pipeline to generate future income.

Valuation

Trailing PE -
Forward PE -
Enterprise Value 27.72M
Price to Sales(TTM) -
Enterprise Value 27.72M
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -4.65
Shares Outstanding 187.90M
Shares Floating 116.41M
Shares Outstanding 187.90M
Shares Floating 116.41M
Percent Insiders 23.08
Percent Institutions 59.9

Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

Form CRS provides a relationship summary of our automated advisory services, flat subscription fees, and conflicts of interest. Form ADV Part 2A brochure contains complete details on services, billing, and disclosures. If any summary differs from our current regulatory filings, the filed Form ADV controls.