enVVeno Medical Corp logo

enVVeno Medical Corp(NVNO)

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ADVISORIES YOU CAN VERIFY
QUALITY SIGNAL
1-STAR RATING
PASS
LAST CLOSE
$8.81
09/28/2026
(24-hour delay)

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*as per simulation (see disclosures)
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Upturn Advisory & Investor View for NVNO

09/28/2026: NVNO (1-star) is currently NOT-A-BUY. Pass it for now.

enVVeno Medical Corp is a clinical-stage medical device firm primarily focused on developing the VenoValve, a surgical solution for chronic venous insufficiency. Its main strength lies in its specialized, potentially breakthrough technology that addresses a large patient segment currently lacking adequate deep vein treatment options. The company's growth story is tied to successful clinical outcomes and eventual FDA approval. Risks include high cash burn, the absence of commercial revenue, and the competitive threat from established medical device incumbents. The stock may suit growth-oriented, high-risk investors who monitor clinical trial results and regulatory news as the primary drivers of long-term value.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorMixed fitThe company offers high-risk, high-reward potential based on clinical outcomes rather than current growth metrics.
Momentum investorStrong fit while signal remains positiveInvestors often trade the stock based on clinical trial updates and news flow regarding regulatory milestones.
Value investorWeak fitThe lack of revenue and negative earnings make it unsuitable for traditional value-based valuation methodologies.
Dividend investorWeak fitThe company is in an early growth phase and does not generate the cash flow required to support dividends.
Low-risk investorWeak fitThe binary nature of clinical outcomes and high cash burn create significant volatility and risk.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighThe stock price is highly sensitive to clinical trial news and speculative sentiment.
Valuation riskHighAs a pre-revenue company, valuation is largely subjective and based on long-term potential.
Competition risk (Medtech incumbents)HighLarge, established players have significantly more resources to defend their market share.
Business qualityMediumThe company holds promising intellectual property but lacks a proven commercial business model.
Dividend incomeLow / noneThere is no current or expected dividend income.
Execution riskHighSuccessfully navigating FDA approval and achieving commercial adoption are high-bar operational challenges.

Price Behavior

Downtrend
PRICE PATH

Downtrend

The stock has experienced a sustained decline in price over recent periods.

Highly Choppy
PRICE STABILITY

Highly Choppy

The stock has experienced frequent, large price swings that make its near-term movement less predictable.

Analysis of Past Performance

Type Stock
Historic Profit -26.51%
Avg. Invested days 21
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 2.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 09/28/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
NVNO receives a 3-star rating, supported by solid analyst coverage. The rating is constrained by weak unit economics, and weak price momentum.

Company Fundamentals

★★★★★
NVNO has moderate overall fundamentals (3 stars), with moderate financial health, moderate growth momentum, and moderate ownership. In FY2025 versus FY2024, solid earnings growth (+10.8%) is partially offset by soft cash generation (FCF margin 0.0%), slightly negative revenue growth (+0.0%), soft profitability (net margin 0.0%).

Financial Health Rating

★★★★★
NVNO's financial health is supported by strong efficiency, including operating-expense and cost-of-revenue discipline (opex 0.0% of revenue). Profitability is weak (1 stars), which helps explain the 3-star overall score.

Growth Momentum Score

★★★★★
Earnings growth is NVNO's strongest growth driver at +10.8% FY2025 versus FY2024 (solid, 4 stars). By comparison, while revenue growth (+0.0%, slightly negative) holds the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 16.0% (soft) and 85.0% of outstanding shares are publicly tradable (strong). Insider ownership of 8.23% supports management-shareholder alignment.

Top 5 Institutional Investors

Kingdon Capital Management LLC 5.21%
CM Management, LLC 5.14%
Geode Capital Management, LLC 1.50%
Vanguard Capital Management, LLC 0.90%
JPMorgan Chase & Co 0.75%

Unit Economics (Per $1K Revenue)

★★★★★
NVNO generates approximately $-0 of gross profit, $-0 of operating income, and $-0 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Weak margins explain the 1-star rating, with weak cash conversion and weak capital efficiency.

Economic Dimensions

★★★★★
Effective Tax Rate: 0.00%

Quantitative Style Profile

★★★★★
NVNO has a liquid profile. Weak momentum is the primary drawback, while soft valuation.

Style Classification

Quality Focused

Small / Mid Cap RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 6.02M USD
Price to earnings Ratio -
1Y Target Price 30
Price to earnings Ratio -
1Y Target Price 30
Volume (30-day avg) 22.2K shares
Beta 1.07
52 Weeks Range 7.01 - 35.17
Updated Date 09/27/2026
52 Weeks Range 7.01 - 35.17
Updated Date 09/27/2026
Dividends yield (FY) -
Basic EPS (TTM) -24.97

How Company Makes Money

Business areaWhat it includesRetail investor read
Venous Intervention ResearchClinical stage research and development of the VenoValve.The company does not currently sell products and earns no revenue; investors are betting on the success of future technology.

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

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Valuation

Trailing PE -
Forward PE -
Enterprise Value -14.96M
Price to Sales(TTM) 216.91
Enterprise Value -14.96M
Price to Sales(TTM) 216.91
Enterprise Value to Revenue 274.86
Enterprise Value to EBITDA -0.87
Shares Outstanding 694.83K
Shares Floating 590.41K
Shares Outstanding 694.83K
Shares Floating 590.41K
Percent Insiders 8.23
Percent Institutions 15.96

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Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

About enVVeno Medical Corp

Exchange NASDAQ
Headquarters Irvine, CA, United States
IPO Launch date 2018-05-31
CEO & Director Mr. Robert A. Berman
Sector Healthcare
Industry Medical Devices
Full time employees 33
Full time employees 33

enVVeno Medical Corporation, a medical device company, focuses on the development of bioprosthetic tissue-based solutions to enhance the standard of care in the treatment of venous disease in the United States. The company's lead product is the VenoValve, a surgical replacement venous valve for the treatment of venous chronic venous insufficiency. Its VenoValve implanted into the femoral vein of the patient in an open surgical procedure via a 5-to-6-inch incision in the upper thigh. The company also develops enVVe, a non-surgical and transcatheter-based replacement venous valve system consisting of the enVVe valve, enVVe delivery system, and delivery system accessories. The company was formerly known as Hancock Jaffe Laboratories, Inc. and changed its name to enVVeno Medical Corporation in October 2021. enVVeno Medical Corporation was incorporated in 1999 and is based in Irvine, California.