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Oculis Holding AG Ordinary shares(OCS)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Stock price based on last close Advisory Performance History (Simulated)
Upturn Advisory & Investor View for OCS
10/23/2026: OCS (1-star) is currently NOT-A-BUY. Pass it for now.
Oculis Holding AG is a clinical-stage biopharmaceutical company focused on developing non-invasive, topical eye drops for chronic ophthalmic conditions. The company's primary strength lies in its proprietary drug delivery platform, which aims to convert invasive treatments into more patient-friendly formulations. Its main investment story centers on the potential commercialization of lead candidates, such as OCS-01, which target large multi-billion dollar markets. Risks are significant, primarily involving clinical trial success, regulatory approvals, and the intense competition from large established pharmaceutical firms. The stock is best suited for growth-oriented investors with a high risk tolerance who are closely monitoring upcoming clinical readouts and trial updates.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Strong fit | The company offers high-growth potential contingent on successful clinical trials and eventual product commercialization. |
| Momentum investor | Mixed fit | This is a conditional fit based on positive news flow regarding clinical trial results and regulatory updates. |
| Value investor | Weak fit | The company lacks current earnings, making traditional value metrics inapplicable at this stage. |
| Dividend investor | Weak fit | Oculis is a clinical-stage biotech and does not provide dividends or income to shareholders. |
| Low-risk investor | Weak fit | The volatility and binary risks associated with clinical development are unsuitable for low-risk portfolios. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | The stock is highly sensitive to news regarding clinical trial results and regulatory decisions. |
| Valuation risk | High | Valuation is speculative and relies on long-term projections of future product market share. |
| Competition risk (Large Pharma) | Medium / high | Large incumbents can outspend the company in commercialization and clinical trial scale. |
| Business quality | Medium | Quality is defined by the strength of the clinical pipeline and intellectual property rather than established earnings. |
| Dividend income | Low / none | Investors should not expect any income from this holding. |
| Execution risk | High | Success depends entirely on the technical and regulatory achievement of clinical milestones. |
Price Behavior
Steep Decline
The stock price has dropped sharply with strong downward pressure.
Extreme Price Shocks
The stock has experienced exceptionally large and disruptive price movements during the period.
Analysis of Past Performance
Type Stock | Historic Profit 21.14% | Avg. Invested days 40 | Today’s Advisory PASS |
Upturn Advisory Rating  | Upturn Advisory Performance  4.0 | Stock Returns Performance  3.0 |
| Profits based on simulation | Last Close 10/23/2026 |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals
Financial Health Rating
Growth Momentum Score
Ownership
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue)
Economic Dimensions
Quantitative Style Profile
Style Classification
Quality Focused
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 486.55M USD | Price to earnings Ratio - | 1Y Target Price 37.05 |
Price to earnings Ratio - | 1Y Target Price 37.05 | ||
Volume (30-day avg) 315.7K shares | Beta 0.27 | 52 Weeks Range 7.11 - 34.48 | Updated Date 10/23/2026 |
52 Weeks Range 7.11 - 34.48 | Updated Date 10/23/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -1.74 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Clinical Development | Oculis does not generate commercial revenue; its value creation is driven by potential future milestones and licensing deals. | The company is currently burning cash to prove its drugs work; it is a long-term play on clinical success. |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 714.47M | Price to Sales(TTM) 414.79 |
Enterprise Value 714.47M | Price to Sales(TTM) 414.79 | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA -3.47 | Shares Outstanding 61.59M | Shares Floating 52.39M |
Shares Outstanding 61.59M | Shares Floating 52.39M | ||
Percent Insiders 3.53 | Percent Institutions 47.1 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
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