OCS official logo OCS
OCS 1-star rating from Upturn Advisory
Oculis Holding AG Ordinary shares (OCS) company logo

Oculis Holding AG Ordinary shares (OCS)

Oculis Holding AG Ordinary shares (OCS) 1-star rating from Upturn Advisory
$19
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Upturn Advisory Summary

11/28/2025: OCS (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

Upturn 1 star rating for performance

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

2 star rating from financial analysts

7 Analysts rated it

Limited analyst coverage, niche firm, research info may be scarce.

1 Year Target Price $43.15

1 Year Target Price $43.15

Analysts Price Target For last 52 week
$43.15 Target price
52w Low $14
Current$19
52w High $23.08

Analysis of Past Performance

Type Stock
Historic Profit 25.04%
Avg. Invested days 42
Today’s Advisory PASS
Upturn Star Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 4.0
Stock Returns Performance Upturn Returns Performance icon 3.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 11/28/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 1.10B USD
Price to earnings Ratio -
1Y Target Price 43.15
Price to earnings Ratio -
1Y Target Price 43.15
Volume (30-day avg) 7
Beta 0.14
52 Weeks Range 14.00 - 23.08
Updated Date 11/30/2025
52 Weeks Range 14.00 - 23.08
Updated Date 11/30/2025
Dividends yield (FY) -
Basic EPS (TTM) -2.68

Earnings Date

Report Date 2025-11-11
When -
Estimate -0.4116
Actual -0.32

Profitability

Profit Margin -
Operating Margin (TTM) -8352.26%

Management Effectiveness

Return on Assets (TTM) -33.35%
Return on Equity (TTM) -92.2%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 920984232
Price to Sales(TTM) 1388.54
Enterprise Value 920984232
Price to Sales(TTM) 1388.54
Enterprise Value to Revenue -
Enterprise Value to EBITDA -3.47
Shares Outstanding 57806909
Shares Floating 39940507
Shares Outstanding 57806909
Shares Floating 39940507
Percent Insiders 5.72
Percent Institutions 38.62

Icon representing Upturn AI-generated SWOT analysis summary Upturn AI SWOT

Oculis Holding AG Ordinary shares

Oculis Holding AG Ordinary shares(OCS) company logo displayed in Upturn AI summary

Company Overview

Company history and background logo History and Background

Oculis Holding AG is a biopharmaceutical company focused on developing ophthalmic treatments. Founded with a vision to address unmet needs in eye care, Oculis has evolved through research, clinical trials, and strategic partnerships.

Company business area logo Core Business Areas

  • Dry Eye Disease (DED): Developing innovative therapies for DED, a prevalent condition affecting tear production and ocular surface health.
  • Diabetic Macular Edema (DME): Developing treatments for DME, a complication of diabetes that can lead to vision loss.
  • Neuro-Ophthalmology: Researching and developing novel therapies for neuro-ophthalmic disorders.

leadership logo Leadership and Structure

The leadership team comprises experienced pharmaceutical executives and scientists. The organizational structure includes research and development, clinical operations, regulatory affairs, and commercial functions.

Top Products and Market Share

Product Key Offerings logo Key Offerings

  • OCS-01: OCS-01 is a high concentration preservative free topical formulation of dexamethasone, used to treat inflammation and pain following ocular surgery as well as DED. Market share is developing but aims to compete with established brands such as Lotemax. Competitors include Bausch + Lomb, Novartis, and Sun Pharma.
  • OCS-02: OCS-02 is a novel TNFu03b1 inhibitor being developed for DME. Market share is developing. Competitors include Regeneron (Eylea), Roche (Vabysmo), and Novartis (Beovu).

Market Dynamics

industry overview logo Industry Overview

The ophthalmic pharmaceutical industry is experiencing growth driven by an aging population, increased prevalence of chronic diseases like diabetes, and advancements in drug delivery technologies.

Positioning

Oculis positions itself as an innovator in ophthalmic treatments, focusing on developing novel therapies that address unmet needs and improve patient outcomes. They target niche markets with high growth potential.

Total Addressable Market (TAM)

The global ophthalmology market is expected to reach hundreds of billions of USD. Oculis is positioned to capture a share of this TAM through its pipeline of innovative products, focusing on areas like dry eye and DME.

Upturn SWOT Analysis

Strengths

  • Innovative pipeline of ophthalmic therapies
  • Experienced management team
  • Strong research and development capabilities
  • Strategic partnerships

Weaknesses

  • Reliance on clinical trial outcomes
  • Competition from established pharmaceutical companies
  • Need to secure regulatory approvals
  • Limited commercial infrastructure

Opportunities

  • Expanding into new ophthalmic indications
  • Acquiring complementary technologies or products
  • Collaborating with other pharmaceutical companies
  • Capitalizing on the growing ophthalmic market

Threats

  • Clinical trial failures
  • Regulatory delays
  • Generic competition
  • Changes in healthcare policies

Competitors and Market Share

Key competitor logo Key Competitors

  • Regeneron (REGN)
  • Novartis (NVS)
  • Bausch + Lomb (BLCO)

Competitive Landscape

Oculis competes with established pharmaceutical companies in the ophthalmic market. Its competitive advantage lies in its innovative pipeline and focus on unmet needs. Disadvantages include limited commercial infrastructure and reliance on clinical trial success.

Growth Trajectory and Initiatives

Historical Growth: Historically, Oculis has focused on building its product pipeline and conducting clinical trials.

Future Projections: Future growth is projected to be driven by successful clinical trial results, regulatory approvals, and commercialization of its ophthalmic therapies. Analyst estimates vary depending on the success of the pipeline.

Recent Initiatives: Recent initiatives include advancing clinical trials for OCS-01 and OCS-02, forming strategic partnerships, and expanding the research and development team.

Summary

Oculis Holding AG Ordinary shares is an innovative biopharmaceutical company focusing on unmet needs in ophthalmology. The company's strength lies in its pipeline, but its future depends on successful clinical trials and commercialization. The competitive environment is challenging, and regulatory hurdles remain a key risk, however the company's niche market focus offers long-term growth potential.

Similar Stocks

Sources and Disclaimers

Data Sources:

  • Company Filings
  • Analyst Reports
  • Industry Publications

Disclaimers:

The information provided is for informational purposes only and does not constitute financial advice. Investment decisions should be based on thorough research and consultation with a qualified financial advisor.

Information icon for Upturn AI Summarization accuracy disclaimer AI Summarization is directionally correct and might not be accurate.

Information icon for Upturn AI Summarization data freshness disclaimer Summarized information shown could be a few years old and not current.

Information icon warning about Upturn AI Fundamental Rating based on potentially old data Fundamental Rating based on AI could be based on old data.

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About Oculis Holding AG Ordinary shares

Exchange NASDAQ
Headquaters -
IPO Launch date 2023-03-02
CEO & Director Dr. Riad Sherif M.B.A., M.D.
Sector Healthcare
Industry Biotechnology
Full time employees 49
Full time employees 49

Oculis Holding AG, a clinical-stage biopharmaceutical company, develops drug candidates to treat ophthalmic diseases in Switzerland, Iceland, and internationally. The company's lead product candidate is OCS-01, a topical dexamethasone optireach formulation, which is in Phase 3 clinical trials for the treatment of diabetic macular edema; OCS-02, a topical biologic candidate that is in Phase 2b clinical trials for the treatment for dry eye disease; and OCS-05, a disease modifying neuroprotective agent for neurological damage with indications for glaucoma, dry age-related macular degeneration and diabetic retinopathy, and acute optic neuritis. Oculis Holding AG was formerly known as Oculis SA and changed its name to Oculis Holding AG in March 2023. The company was founded in 2017 and is based in Zug, Switzerland.