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Upturn AI Summary - About
Passage Bio Inc(PASG)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Advisory Performance History (Simulated)
Upturn Advisory & Investor View for PASG
10/30/2026: PASG (1-star) is currently NOT-A-BUY. Pass it for now.
Passage Bio is a clinical-stage biotechnology company focused on developing AAV-based gene therapies for rare central nervous system disorders. Its primary strength lies in a deep research partnership with the University of Pennsylvania, providing a stable foundation for its therapeutic pipeline. The investment story centers on the potential to bring life-changing, one-time treatments to patients with significant unmet needs. However, the company faces substantial risks, including the inherent uncertainty of clinical trials, lack of current revenue, and the necessity of further capital raises. It is best suited for speculative investors comfortable with high risk and long-term development cycles, with close monitoring of clinical data readouts essential.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Mixed fit | The company offers high-risk, high-reward potential based on clinical trial success, but lacks established growth in revenue. |
| Momentum investor | Weak fit | Momentum is generally lacking due to the extended nature of drug development cycles in this sector. |
| Value investor | Weak fit | There are no traditional earnings or book value metrics to support a value-based investment thesis. |
| Dividend investor | Weak fit | The company does not pay dividends and requires significant capital for R&D. |
| Low-risk investor | Weak fit | The high volatility and binary outcomes of clinical trials make this unsuitable for low-risk investors. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | Clinical-stage biotechnology stocks often experience sharp price swings based on trial data announcements. |
| Valuation risk | Medium / high | Valuations are difficult to determine and depend heavily on discounted cash flow projections of potential future therapies. |
| Competition risk (Gene therapy developers) | High | Established players may achieve faster clinical milestones or superior therapeutic results. |
| Business quality | Medium | The company is reliant on external intellectual property and must demonstrate its ability to execute clinical programs. |
| Dividend income | Low / none | The company is in a capital-intensive development phase and does not generate income for shareholders. |
| Execution risk | High | Successful clinical execution is the primary factor for survival and value creation in this business model. |
Price Behavior

Steep Decline
The stock price has dropped sharply with strong downward pressure.

Extreme Price Shocks
The stock has experienced exceptionally large and disruptive price movements during the period.
Analysis of Past Performance
Type Stock | Historic Profit -34.74% | Avg. Invested days 16 | Today’s Advisory PASS |
Upturn Advisory Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals 
Financial Health Rating 
Growth Momentum Score 
Ownership 
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue) 
Economic Dimensions
Quantitative Style Profile 
Style Classification
Quality Focused
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 11.10M USD | Price to earnings Ratio - | 1Y Target Price 15.5 |
Price to earnings Ratio - | 1Y Target Price 15.5 | ||
Volume (30-day avg) 19.8K shares | Beta 1.39 | 52 Weeks Range 3.29 - 20.00 | Updated Date 10/31/2026 |
52 Weeks Range 3.29 - 20.00 | Updated Date 10/31/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -10.92 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Clinical Development | Developing novel gene therapies for rare CNS diseases; currently pre-revenue. | The company does not yet sell products and spends money to develop new medicines that could be very valuable if approved. |
Valuation
Trailing PE - | Forward PE - | Enterprise Value -12.64M | Price to Sales(TTM) - |
Enterprise Value -12.64M | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA 0.87 | Shares Outstanding 3.22M | Shares Floating 3.20M |
Shares Outstanding 3.22M | Shares Floating 3.20M | ||
Percent Insiders 7.71 | Percent Institutions 46.35 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

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