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Upturn stock rating
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Pacira BioSciences, Inc. (PCRX)

Upturn stock rating
$23.45
Last Close (24-hour delay)
upturn advisory
PASS
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  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
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Upturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
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  • WEEK

Upturn Advisory Summary

10/15/2025: PCRX (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

6 Analysts rated it

Limited analyst coverage, niche firm, research info may be scarce.

1 Year Target Price $29

1 Year Target Price $29

Analysts Price Target For last 52 week
$29 Target price
52w Low $16
Current$23.45
52w High $27.64

Analysis of Past Performance

Type Stock
Historic Profit -1.69%
Avg. Invested days 31
Today’s Advisory PASS
Upturn Star Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulation Last Close 10/15/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 1.03B USD
Price to earnings Ratio -
1Y Target Price 29
Price to earnings Ratio -
1Y Target Price 29
Volume (30-day avg) 6
Beta 0.41
52 Weeks Range 16.00 - 27.64
Updated Date 10/17/2025
52 Weeks Range 16.00 - 27.64
Updated Date 10/17/2025
Dividends yield (FY) -
Basic EPS (TTM) -2.75

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -18.06%
Operating Margin (TTM) 5.04%

Management Effectiveness

Return on Assets (TTM) 2.69%
Return on Equity (TTM) -15.57%

Valuation

Trailing PE -
Forward PE 7.36
Enterprise Value 1289985282
Price to Sales(TTM) 1.46
Enterprise Value 1289985282
Price to Sales(TTM) 1.46
Enterprise Value to Revenue 1.83
Enterprise Value to EBITDA 4.96
Shares Outstanding 44932721
Shares Floating 39823871
Shares Outstanding 44932721
Shares Floating 39823871
Percent Insiders 1.81
Percent Institutions 115.3

ai summary icon Upturn AI SWOT

Pacira BioSciences, Inc.

stock logo

Company Overview

overview logo History and Background

Pacira BioSciences, Inc. was founded in 2006. It focuses on developing and commercializing novel pharmaceutical products, with a primary focus on non-opioid pain management.

business area logo Core Business Areas

  • EXPAREL: Non-opioid postsurgical pain management. It is a bupivacaine liposome injectable suspension indicated for single-dose infiltration to produce postsurgical analgesia and as an interscalene brachial plexus nerve block to produce postsurgical analgesia. Its success has made it the primary revenue driver for Pacira.
  • ioverau00b0: A handheld cryoanalgesia device used to deliver precise cold therapy to target peripheral nerves, providing immediate pain relief without opioids.
  • PharmaEssentia: This is a partnership. Pacira is marketing in the US RUSPERDAu00ae for polycythemia vera

leadership logo Leadership and Structure

Dave Stack is the Chairman and Chief Executive Officer. The organizational structure includes departments such as Research and Development, Commercial Operations, Finance, and Legal, reporting to executive leadership.

Top Products and Market Share

overview logo Key Offerings

  • EXPAREL: EXPAREL is Pacira's lead product, a non-opioid postsurgical pain reliever. Revenue from EXPAREL in 2023 was approximately $660 million. Competitors include generic bupivacaine and other pain management therapies, including opioids and nerve blocks using different formulations. Pacira has a significant market share in the non-opioid postsurgical pain management space.
  • ioverau00b0: ioverau00b0 is a cryoanalgesia system for pain relief. While specific market share data is less readily available, it's considered a growing segment within pain management devices. Competitors include other cryoanalgesia and nerve ablation technologies from companies like Halyard Health (now Avanos Medical) and Boston Scientific.
  • RUSPERDA: RUSPERDA is a prescription medicine used to treat adults with polycythemia vera. This drug is new to Pacira's product portfolio and revenue numbers and market share are still being accumulated. Competitors include other treatment options for polycythemia vera like HUYA BioScience International

Market Dynamics

industry overview logo Industry Overview

The pain management market is large and growing, driven by an aging population and increasing demand for non-opioid alternatives due to concerns about opioid addiction. The market includes pharmaceuticals, devices, and therapies.

Positioning

Pacira BioSciences is positioned as a leader in non-opioid pain management, primarily through EXPAREL. Its competitive advantages include its proprietary liposomal technology and strong clinical data.

Total Addressable Market (TAM)

The global pain management market is expected to reach hundreds of billions of dollars. Pacira is positioned to capture a growing share of this market with its non-opioid alternatives.

Upturn SWOT Analysis

Strengths

  • Leading non-opioid pain management product (EXPAREL)
  • Proprietary liposomal technology
  • Established sales and marketing infrastructure
  • Strong clinical data supporting product efficacy

Weaknesses

  • Reliance on EXPAREL for revenue
  • Potential for generic competition
  • High research and development expenses
  • Regulatory risk associated with pharmaceutical products

Opportunities

  • Expanding indications for EXPAREL
  • Acquiring or partnering with other pain management companies
  • Developing new non-opioid pain management products
  • Expanding into international markets

Threats

  • Generic competition for EXPAREL
  • Changes in healthcare regulations
  • Development of competing non-opioid pain management products
  • Economic downturn affecting healthcare spending

Competitors and Market Share

competitor logo Key Competitors

  • BSX
  • HCSG
  • ITCI

Competitive Landscape

Pacira has a competitive advantage in the non-opioid pain management market due to EXPAREL. However, they face competition from larger pharmaceutical and medical device companies.

Major Acquisitions

Flexion Therapeutics

  • Year: 2021
  • Acquisition Price (USD millions): 450
  • Strategic Rationale: Expanded Pacira's portfolio with Zilretta, an intra-articular steroid injection for osteoarthritis knee pain.

Growth Trajectory and Initiatives

Historical Growth: Pacira has experienced significant growth, driven by EXPAREL adoption and acquisitions.

Future Projections: Analysts project continued revenue growth, driven by EXPAREL expansion and new product launches.

Recent Initiatives: Recent initiatives include expanding the indications for EXPAREL, strategic partnerships, and potential acquisitions.

Summary

Pacira BioSciences is a leader in non-opioid pain management, primarily due to the success of EXPAREL. The company is growing through product expansion and strategic acquisitions. Future challenges include potential generic competition and the need to continue innovating. Pacira's focus on alternatives to opioids positions it well in the current healthcare environment. However, they must continue to diversify their product line to mitigate risks related to reliance on EXPAREL.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company filings (SEC)
  • Analyst reports
  • Press releases
  • Company website

Disclaimers:

The information provided is for informational purposes only and should not be considered financial advice. Investment decisions should be based on individual circumstances and consultation with a qualified financial advisor. Market data is subject to change.

Upturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Pacira BioSciences, Inc.

Exchange NASDAQ
Headquaters Tampa, FL, United States
IPO Launch date 2011-02-03
CEO & Director Mr. Frank D. Lee
Sector Healthcare
Industry Drug Manufacturers - Specialty & Generic
Full time employees 788
Full time employees 788

Pacira BioSciences, Inc. engages in the development, manufacture, marketing, distribution, and sale of non-opioid pain management and regenerative health solutions to healthcare practitioners in the United States. The company offers EXPAREL, a bupivacaine liposome injectable suspension for postsurgical pain management; ZILRETTA, a triamcinolone acetonide extended-release injectable suspension indicated for the management of osteoarthritis and knee pain; and iovera system, a non-opioid handheld cryoanalgesia device used to deliver controlled doses of cold temperature to targeted nerves to produce neurolytic block that interrupts the pain-transmitting signals of a peripheral nerve. It also develops PCRX-201, a novel gene therapy vector platform enabling local administration of genetic medicines with the potential to treat large prevalent diseases like osteoarthritis. The company has a development and commercialization, and supply agreement with Aratana Therapeutics, Inc. for NOCITA, a bupivacaine liposome injectable suspension product for use in animals. The company was formerly known as Pacira Pharmaceuticals, Inc. and changed its name to Pacira BioSciences, Inc. in April 2019. Pacira BioSciences, Inc. was incorporated in 2006 and is headquartered in Tampa, Florida.