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Pacira BioSciences, Inc. (PCRX)

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Upturn Advisory Summary
12/05/2025: PCRX (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $30.17
1 Year Target Price $30.17
| 1 | Strong Buy |
| 1 | Buy |
| 3 | Hold |
| 1 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -1.69% | Avg. Invested days 31 | Today’s Advisory PASS |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 1.08B USD | Price to earnings Ratio 51.04 | 1Y Target Price 30.17 |
Price to earnings Ratio 51.04 | 1Y Target Price 30.17 | ||
Volume (30-day avg) 6 | Beta 0.23 | 52 Weeks Range 18.17 - 27.64 | Updated Date 12/7/2025 |
52 Weeks Range 18.17 - 27.64 | Updated Date 12/7/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) 0.47 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin 2.99% | Operating Margin (TTM) 7.33% |
Management Effectiveness
Return on Assets (TTM) 2.89% | Return on Equity (TTM) 2.9% |
Valuation
Trailing PE 51.04 | Forward PE 7.36 | Enterprise Value 1211054387 | Price to Sales(TTM) 1.5 |
Enterprise Value 1211054387 | Price to Sales(TTM) 1.5 | ||
Enterprise Value to Revenue 1.69 | Enterprise Value to EBITDA 8.19 | Shares Outstanding 43021275 | Shares Floating 42529972 |
Shares Outstanding 43021275 | Shares Floating 42529972 | ||
Percent Insiders 1.88 | Percent Institutions 113.78 |
Upturn AI SWOT
Pacira BioSciences, Inc.

Company Overview
History and Background
Pacira BioSciences, Inc. was founded in 2007 as Depomed, Inc., and later rebranded to Pacira Biosciences in 2018. The company is a prominent specialty pharmaceutical company focused on developing and commercializing innovative products for surgical recovery and pain management. A significant milestone was the acquisition of DepoMed in 2014, which brought key pain management products into its portfolio. In 2018, the rebranding to Pacira Biosciences signaled a strategic shift towards a broader focus on non-opioid pain management and surgical solutions.
Core Business Areas
- Non-Opioid Pain Management: Pacira BioSciences focuses on developing and commercializing non-opioid alternatives for post-operative pain management, aiming to reduce reliance on opioids and improve patient outcomes. This includes their flagship product, EXPAREL.
- Surgical Recovery and Aesthetics: The company also engages in developing solutions that enhance recovery after surgery and in the aesthetic market, further diversifying its offerings beyond pain management.
Leadership and Structure
Pacira BioSciences is led by a seasoned management team with extensive experience in the pharmaceutical and biotechnology industries. The organizational structure is typical of a specialty pharmaceutical company, with divisions dedicated to research and development, manufacturing, commercial operations (sales and marketing), and corporate functions.
Top Products and Market Share
Key Offerings
- Description: EXPAREL is a non-opioid, local anesthetic that, when injected at the surgical site, provides post-operative analgesia for up to 72 hours. It is designed to reduce or eliminate the need for systemic opioid pain medications after surgery. Competitors in this space include other local anesthetics and long-acting formulations, as well as various opioid analgesics. Its market share is significant within the post-operative pain management segment for specific surgical procedures.
- Product Name 1: EXPAREL (depot bupivacaine solution)
- Description: ZIPRA is another non-opioid pain management product in Pacira's pipeline, aiming to further expand their offerings in this therapeutic area. Specific market share data or revenue from this product may be limited as it may be in earlier stages of development or commercialization compared to EXPAREL. Competitors would include a wide range of pain management solutions.
- Product Name 2: ZIPRA (non-opioid pain management)
Market Dynamics
Industry Overview
The pharmaceutical market, particularly in pain management and surgical recovery, is characterized by intense competition, stringent regulatory oversight, and a growing demand for non-opioid alternatives due to the opioid crisis. There's a significant push from healthcare providers, payers, and patients for solutions that offer effective pain relief with reduced side effects and abuse potential.
Positioning
Pacira BioSciences is well-positioned as a leader in non-opioid pain management, with EXPAREL being a cornerstone of its strategy. The company differentiates itself through its innovative drug delivery technology and its focus on addressing a critical unmet need in post-operative care. Its competitive advantages lie in its proprietary technology, established market presence, and strong relationships with healthcare providers.
Total Addressable Market (TAM)
The TAM for pain management is substantial, encompassing a wide range of conditions and patient populations. For post-operative pain alone, the market is valued in billions of dollars globally. Pacira BioSciences is strategically focused on capturing a significant portion of the surgical pain management segment, with EXPAREL targeting a considerable portion of surgical procedures where long-lasting, non-opioid analgesia is beneficial.
Upturn SWOT Analysis
Strengths
- Proprietary drug delivery technology (DepoFoam)
- Established market presence with EXPAREL
- Strong focus on non-opioid pain management
- Experienced management team
- Potential for pipeline expansion
Weaknesses
- Reliance on a few key products, particularly EXPAREL
- Patent expirations for key products
- High research and development costs
- Competition from generic and biosimilar drugs
Opportunities
- Growing demand for non-opioid pain management solutions
- Expansion of EXPAREL indications and geographies
- Development of new products in the pipeline
- Strategic partnerships and acquisitions
- Increasing awareness and adoption of opioid-sparing strategies
Threats
- Intense competition from established pharmaceutical companies and emerging biotechs
- Pricing pressures from payers and government entities
- Regulatory hurdles and challenges
- Litigation and patent challenges
- Economic downturns affecting healthcare spending
Competitors and Market Share
Key Competitors
- Pfizer Inc. (PFE)
- AbbVie Inc. (ABBV)
- Johnson & Johnson (JNJ)
- Merck & Co., Inc. (MRK)
- Bristol Myers Squibb Company (BMY)
Competitive Landscape
Pacira BioSciences holds a strong position in the niche market of long-acting, non-opioid post-operative pain management. Its primary advantage lies in its pioneering work with EXPAREL and its established reputation in this segment. However, it faces competition from larger pharmaceutical companies with broader portfolios of pain management drugs, as well as from emerging companies developing novel pain therapies. Generic competition for older anesthetics also poses a threat. Pacira's disadvantages include its smaller size and reliance on a few key products compared to its larger, more diversified competitors.
Growth Trajectory and Initiatives
Historical Growth: Pacira BioSciences has experienced significant historical growth, largely attributed to the successful commercialization and expansion of EXPAREL into various surgical specialties. This growth has been fueled by increasing physician adoption and patient demand for non-opioid pain relief.
Future Projections: Future growth is projected to be driven by continued expansion of EXPAREL's indications, potential new product launches from its pipeline, and advancements in its technology platforms. Analyst estimates often forecast continued revenue growth, though the pace may be influenced by competitive dynamics and market access.
Recent Initiatives: Recent initiatives likely include efforts to expand the therapeutic areas where EXPAREL is used, research into new drug delivery technologies, potential strategic partnerships, and ongoing efforts to secure market access and favorable reimbursement for its products.
Summary
Pacira BioSciences is a strong player in the non-opioid pain management market, with EXPAREL as its flagship product. The company benefits from a clear market need and a focused strategy. Its key strength lies in its proprietary drug delivery technology and established market presence. However, it faces challenges from patent expirations and intense competition from larger pharmaceutical players. Pacira needs to focus on expanding its product pipeline and diversifying its revenue streams to mitigate risks and ensure sustained growth.
Similar Stocks
Sources and Disclaimers
Data Sources:
- Company Investor Relations Websites
- Financial News Outlets (e.g., Bloomberg, Reuters)
- Market Research Reports
- SEC Filings (10-K, 10-Q)
Disclaimers:
This JSON output is generated based on publicly available information and is intended for informational purposes only. It does not constitute financial advice or a recommendation to buy, sell, or hold any securities. Users should conduct their own due diligence and consult with a qualified financial advisor before making any investment decisions. Market share data and TAM estimates are subject to interpretation and may vary across different research sources.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Pacira BioSciences, Inc.
Exchange NASDAQ | Headquaters Tampa, FL, United States | ||
IPO Launch date 2011-02-03 | CEO & Director Mr. Frank D. Lee | ||
Sector Healthcare | Industry Drug Manufacturers - Specialty & Generic | Full time employees 788 | Website https://www.pacira.com |
Full time employees 788 | Website https://www.pacira.com | ||
Pacira BioSciences, Inc. engages in the development, manufacture, marketing, distribution, and sale of non-opioid pain management and regenerative health solutions to healthcare practitioners in the United States. The company offers EXPAREL, a bupivacaine liposome injectable suspension for postsurgical pain management; ZILRETTA, a triamcinolone acetonide extended-release injectable suspension indicated for the management of osteoarthritis and knee pain; and iovera system, a non-opioid handheld cryoanalgesia device used to deliver controlled doses of cold temperature to targeted nerves to produce neurolytic block that interrupts the pain-transmitting signals of a peripheral nerve. It also develops PCRX-201, a novel gene therapy vector platform enabling local administration of genetic medicines with the potential to treat large prevalent diseases like osteoarthritis. The company has a development and commercialization, and supply agreement with Aratana Therapeutics, Inc. for NOCITA, a bupivacaine liposome injectable suspension product for use in animals. The company was formerly known as Pacira Pharmaceuticals, Inc. and changed its name to Pacira BioSciences, Inc. in April 2019. Pacira BioSciences, Inc. was incorporated in 2006 and is headquartered in Tampa, Florida.

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