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Pharvaris BV(PHVS)

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ADVISORIES YOU CAN VERIFY
QUALITY SIGNAL RECENCY
2-STAR RATING
Consider higher Upturn Star rating
BUY for 21 days
PROFIT SINCE LAST BUY
+7.76%
LAST CLOSE
$38.06
09/15/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
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Upturn Advisory & Investor View for PHVS

09/15/2026: PHVS (2-star) has a low Upturn Star Rating. Not recommended to BUY.

Pharvaris BV is a clinical-stage biotechnology company focused on developing oral bradykinin B2-receptor antagonists to treat hereditary angioedema (HAE). Its primary strength is a specialized pipeline that seeks to replace injectable therapies with a more convenient once-daily oral pill. The main investment opportunity lies in the potential for its lead candidate, deucrictibant, to capture significant market share if it achieves regulatory approval. However, the company faces substantial execution, competitive, and financial risks, as it currently lacks commercial revenue. The stock is best suited for risk-tolerant investors with a high appetite for speculative biotechnology ventures who are closely monitoring clinical trial news and regulatory outcomes.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorMixed fitThis is a high-risk, high-reward play on future drug approval that may appeal to those seeking long-term capital appreciation.
Momentum investorStrong fit while signal remains positiveThe stock often reacts sharply to clinical and regulatory news cycles, creating significant short-term trading opportunities.
Value investorWeak fitThe company lacks current earnings or traditional value metrics, making it unsuitable for standard value-based investing.
Dividend investorWeak fitThe company does not pay dividends and operates in a cash-burning phase.
Low-risk investorWeak fitThe extreme volatility associated with pre-commercial biotech development poses significant capital risk.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighClinical trial results can cause massive swings in share price.
Valuation riskHighValuations are driven by future potential, which is inherently speculative.
Competition risk (HAE treatments)HighEntrenched incumbents may protect their market share aggressively.
Business qualityMediumThe firm is specialized but pre-revenue, lacking a commercial track record.
Dividend incomeLow / noneInvestors should not expect income from this equity.
Execution riskMedium / highSuccess depends entirely on successful clinical trials and regulatory approval.

Price Behavior

Strong Uptrend
PRICE PATH

Strong Uptrend

The stock has maintained a strong upward price trend across the last three quarters.

Moderately Choppy
PRICE STABILITY

Moderately Choppy

The stock has experienced noticeable price swings while retaining some directional structure.

Analysis of Past Performance

Type Stock
Historic Profit -6.51%
Avg. Invested days 39
Today’s Advisory Consider higher Upturn Star rating
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 3.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 09/15/2026

Upturn Scorecard

Upturn Star Rating

PHVS receives a 3-star rating, supported by solid analyst coverage. The rating is constrained by weak unit economics, and weak price momentum.

Company Fundamentals

PHVS has moderate overall fundamentals (3 stars), with moderate financial health, soft growth momentum, and solid ownership. In FY2025 versus FY2024, growth and ownership metrics are mixed: negative earnings growth (-30.9%), soft cash generation (FCF margin 0.0%), slightly negative revenue growth (+0.0%).

Financial Health Rating

PHVS's financial health is supported by strong efficiency, including operating-expense and cost-of-revenue discipline (opex 0.0% of revenue). Profitability is weak (1 stars), which helps explain the 3-star overall score.

Growth Momentum Score

PHVS's growth profile is soft, with the least-weak measure being revenue growth at +0.0% FY2025 versus FY2024. By comparison, while earnings growth (-30.9%, negative) and free-cash-flow growth (-13.7%, negative) hold the profile back, so recent growth is not broad-based across the business.

Ownership

Institutional ownership is 93.1% and approximately 62.2% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 6.08% supports management-shareholder alignment.

Top 5 Institutional Investors

General Atlantic Llc 9.33%
FMR Inc 8.95%
Foresite Capital Management IV, LLC 6.81%
venBio Partners LLC 6.61%
Viking Global Investors LP 5.20%

Unit Economics (Per $1K Revenue)

PHVS generates approximately $0 of gross profit, $-0 of operating income, and $-0 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Strong margins, cash conversion, and capital efficiency support the rating.

Economic Dimensions

Effective Tax Rate: -1.14% (Tax Credit)

Quantitative Style Profile

PHVS has a liquid, relatively low-volatility profile. Weak momentum is the primary drawback.

Style Classification

Quality Focused

Low VolatilitySmall / Mid Cap RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Mid-Cap Stock
Market Capitalization 2.73B USD
Price to earnings Ratio -
1Y Target Price 58.63
Price to earnings Ratio -
1Y Target Price 58.63
Volume (30-day avg) 941.0K shares
Beta -2.32
52 Weeks Range 20.65 - 43.25
Updated Date 09/15/2026
52 Weeks Range 20.65 - 43.25
Updated Date 09/15/2026
Dividends yield (FY) -
Basic EPS (TTM) -3.03

How Company Makes Money

Business areaWhat it includesRetail investor read
HAE TherapeuticsDevelopment of deucrictibant for HAE.The company currently makes no money; it is betting on the future sale of a breakthrough pill.
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Valuation

Trailing PE -
Forward PE -
Enterprise Value 2.36B
Price to Sales(TTM) -
Enterprise Value 2.36B
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -1.38
Shares Outstanding 70.20M
Shares Floating 43.70M
Shares Outstanding 70.20M
Shares Floating 43.70M
Percent Insiders 6.08
Percent Institutions 93.14

Icon representing Upturn AI-generated SWOT analysis summary Upturn AI Summary

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Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

About Pharvaris BV

Exchange NASDAQ
Headquarters -
IPO Launch date 2021-02-05
Co-Founder, CEO & Executive Director Mr. Berndt Axel Edvard Modig CPA, M.B.A.
Sector Healthcare
Industry Biotechnology
Full time employees 148
Full time employees 148

Pharvaris N.V., a late-stage biopharmaceutical company, focuses on the development and commercialization of therapies for rare diseases with unmet needs covering angioedema and other bradykinin-mediated diseases. The company develops deucrictibant, a small molecule bradykinin B2-receptor antagonist to treat attacks due to bradykinin-mediated angioedema, including hereditary angioedema (HAE) and acquired angioedema due to C1-inhibitor deficiency (AAE-C1INH), which is in phase 3, as well as in phase 3 trials for treatment and prophylaxis of HAE attacks; and extended-release tablet and immediate-release capsule formulation of deucrictibant. Pharvaris N.V. was incorporated in 2015 and is headquartered in Zug, Switzerland.