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Pmv Pharmaceuticals Inc (PMVP)

Upturn stock ratingUpturn stock rating
$0.93
Last Close (24-hour delay)
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PASS
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  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
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  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
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Upturn Advisory Summary

06/04/2025: PMVP (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

5 Analysts rated it

Moderately tracked stock, growing coverage, gaining market and investor attention.

1 Year Target Price $5.67

1 Year Target Price $5.67

Analysts Price Target For last 52 week
$5.67Target price
Low$0.81
Current$0.93
high$1.82

Analysis of Past Performance

Type Stock
Historic Profit -37.46%
Avg. Invested days 33
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 06/04/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 55.59M USD
Price to earnings Ratio -
1Y Target Price 5.67
Price to earnings Ratio -
1Y Target Price 5.67
Volume (30-day avg) 5
Beta 1.43
52 Weeks Range 0.81 - 1.82
Updated Date 06/30/2025
52 Weeks Range 0.81 - 1.82
Updated Date 06/30/2025
Dividends yield (FY) -
Basic EPS (TTM) -1.18

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -27.24%
Return on Equity (TTM) -32.66%

Valuation

Trailing PE -
Forward PE -
Enterprise Value -103692633
Price to Sales(TTM) -
Enterprise Value -103692633
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA 1.24
Shares Outstanding 51952700
Shares Floating 33083986
Shares Outstanding 51952700
Shares Floating 33083986
Percent Insiders 3.23
Percent Institutions 78.16

Analyst Ratings

Rating 3
Target Price 5.67
Buy 1
Strong Buy 4
Buy 1
Strong Buy 4
Hold -
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Pmv Pharmaceuticals Inc

stock logo

Company Overview

overview logo History and Background

PMV Pharmaceuticals, Inc. is a precision oncology company pioneering the discovery and development of small molecule, tumor-agnostic therapies that target p53. Founded in 2013, the company focuses on restoring p53 activity in tumors with p53 mutations.

business area logo Core Business Areas

  • Oncology Drug Development: PMV Pharmaceuticals focuses on discovering and developing small molecule therapies that activate mutant p53 proteins in cancer cells. Their main efforts are in clinical trials for their leading drug candidates.

leadership logo Leadership and Structure

David M. Reese is the President and CEO. The company is structured around research and development, clinical operations, and corporate functions.

Top Products and Market Share

overview logo Key Offerings

  • PCM-012: PCM-012 is PMV Pharmaceuticals' lead clinical-stage candidate, a small molecule designed to selectively bind to and stabilize mutant p53 protein, restoring its tumor-suppressing activity. There is no current market share as the product is in clinical development. Competitors are other companies exploring similar p53 pathways but with different methods or targets.

Market Dynamics

industry overview logo Industry Overview

The oncology market is a large and rapidly growing field. Precision oncology, focusing on targeted therapies based on genetic mutations, is a significant trend.

Positioning

PMV Pharmaceuticals is positioned within the precision oncology market with its unique approach to activating mutant p53. Its competitive advantage lies in its specific targeting mechanism.

Total Addressable Market (TAM)

The total addressable market is significant due to the prevalence of p53 mutations in cancers. Estimates suggest hundreds of thousands of patients could benefit, representing a multi-billion dollar market. PMV is positioned to capture a portion of this TAM upon successful commercialization of its drugs.

Upturn SWOT Analysis

Strengths

  • Novel approach to p53 activation
  • Experienced management team
  • Strong intellectual property portfolio
  • Clinical-stage product candidate

Weaknesses

  • Reliance on single product candidate
  • Limited financial resources compared to larger pharmaceutical companies
  • Clinical trial risks
  • Lack of approved products and revenue

Opportunities

  • Successful clinical trials and regulatory approvals
  • Partnerships with larger pharmaceutical companies
  • Expansion into new cancer indications
  • Development of next-generation p53 activators

Threats

  • Clinical trial failures
  • Competition from other oncology therapies
  • Regulatory hurdles
  • Patent challenges

Competitors and Market Share

competitor logo Key Competitors

  • MRTX
  • ARRY
  • GILD

Competitive Landscape

PMV Pharmaceuticals faces competition from established oncology companies with approved therapies and those developing novel targeted therapies. The company differentiates itself through its unique approach to activating mutant p53.

Growth Trajectory and Initiatives

Historical Growth: PMV Pharmaceuticals' growth is linked to the progression of its clinical programs. Stock fluctuations reflect clinical trial results.

Future Projections: Future growth depends on successful clinical trials, regulatory approvals, and potential commercialization of PCM-012 and other pipeline candidates. Analyst estimates vary widely.

Recent Initiatives: Recent initiatives include enrolling patients in clinical trials for PCM-012 and expanding the pipeline with preclinical programs.

Summary

PMV Pharmaceuticals is a clinical-stage company with a promising but risky approach to cancer treatment. The company's success hinges on positive clinical trial outcomes for its lead candidate. Its focus on p53 activation is innovative, but it must overcome challenges related to clinical development and competition. Recent initiatives to advance clinical trials are encouraging but funding and results are vital for long term success.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • PMV Pharmaceuticals Investor Relations
  • SEC Filings
  • Analyst Reports

Disclaimers:

This analysis is for informational purposes only and should not be considered financial advice. Data is based on available information and may be subject to change. Market share information is estimated and may not be precise.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Pmv Pharmaceuticals Inc

Exchange NASDAQ
Headquaters Princeton, NJ, United States
IPO Launch date 2020-09-25
Co-Founder, CEO, President & Director Dr. David H. Mack Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 47
Full time employees 47

PMV Pharmaceuticals, Inc., a precision oncology company, engages in the discovery and development of small molecule and tumor-agnostic therapies for p53 mutations in cancer. It's lead product candidate is rezatapopt, an orally available small molecule that potently and selectively correct p53 misfolding caused by p53 mutation, Y220C, while sparing wild-type p53. The company was formerly known as PJ Pharmaceuticals, Inc. and changed its name to PMV Pharmaceuticals, Inc. in July 2013. PMV Pharmaceuticals, Inc. was incorporated in 2013 and is based in Princeton, New Jersey.