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Uniqure NV(QURE)

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ADVISORIES YOU CAN VERIFY
QUALITY SIGNAL RECENCY
1-STAR RATING
SELL
SELL for 4 days
PROFIT SINCE LAST BUY
-1.96%
LAST CLOSE
$43.1
09/15/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
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  • 1Y
  • 1M
  • 1W
  • BUY Advisory
  • SELL Advisory (Profit)
  • SELL Advisory (Loss)
  • Profit
  • Loss
  • PASS (Skip)
Upturn Stock price based on last close iconStock price based on last close

Advisory Performance History (Simulated)Advisory Performance History info

Upturn Advisory & Investor View for QURE

09/15/2026: QURE (1-star) is a SELL. SELL for 4 days. Simulated Profits (-1.96%). Updated daily EoD!

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Price Behavior

Strong Uptrend
PRICE PATH

Strong Uptrend

The stock has maintained a strong upward price trend across the last three quarters.

Extreme Price Shocks
PRICE STABILITY

Extreme Price Shocks

The stock has experienced exceptionally large and disruptive price movements during the period.

Analysis of Past Performance

Type Stock
Historic Profit -42.26%
Avg. Invested days 19
Today’s Advisory SELL
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 1.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 09/15/2026

Upturn Scorecard

Upturn Star Rating

QURE receives a 3-star rating, supported by solid analyst coverage. The rating is constrained by soft unit economics, and weak price momentum.

Company Fundamentals

QURE has moderate overall fundamentals (3 stars), with soft financial health, moderate growth momentum, and solid ownership. In FY2025 versus FY2024, solid earnings growth (+16.9%) is partially offset by soft cash generation (FCF margin -1105.5%), negative revenue growth (-40.6%), soft profitability (net margin -1236.0%).

Financial Health Rating

QURE's financial health is supported by moderate liquidity, including working-capital and asset support (WC/assets 71.9%). Cash strength is soft (2 stars), which helps explain the 2-star overall score.

Growth Momentum Score

Earnings growth is QURE's strongest growth driver at +16.9% FY2025 versus FY2024 (solid, 4 stars). By comparison, while revenue growth (-40.6%, negative) holds the profile back, so recent growth is not broad-based across the business.

Ownership

Institutional ownership is 98.0% and approximately 82.9% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 1.26% provides only moderate management-shareholder alignment.

Top 5 Institutional Investors

venBio Select Advisor LLC 8.59%
Aberdeen Group PLC 4.11%
JPMorgan Chase & Co 4.09%
RTW INVESTMENTS, LLC 3.73%
State Street Corp 3.26%

Unit Economics (Per $1K Revenue)

QURE generates approximately $895 of gross profit, $-11,668 of operating income, and $-11,055 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Strong cash conversion and healthy margins support the rating, although capital efficiency remains below the highest tier.

Economic Dimensions

Effective Tax Rate: -2.91% (Tax Credit)

Quantitative Style Profile

QURE has a liquid profile. Weak momentum is the primary drawback, while valuation that is moderately attractive rather than deeply discounted.

Style Classification

Quality Focused

Small / Mid Cap RiskShort Squeeze RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Mid-Cap Stock
Market Capitalization 2.99B USD
Price to earnings Ratio -
1Y Target Price 69.27
Price to earnings Ratio -
1Y Target Price 69.27
Volume (30-day avg) 1.1M shares
Beta 0.94
52 Weeks Range 8.73 - 71.50
Updated Date 09/16/2026
52 Weeks Range 8.73 - 71.50
Updated Date 09/16/2026
Dividends yield (FY) -
Basic EPS (TTM) -4.06

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

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Valuation

Trailing PE -
Forward PE 27.93
Enterprise Value 2.37B
Price to Sales(TTM) 160.12
Enterprise Value 2.37B
Price to Sales(TTM) 160.12
Enterprise Value to Revenue 126.88
Enterprise Value to EBITDA 1.4
Shares Outstanding 69.37M
Shares Floating 57.52M
Shares Outstanding 69.37M
Shares Floating 57.52M
Percent Insiders 1.26
Percent Institutions 98.04

Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

About Uniqure NV

Exchange NASDAQ
Headquarters -
IPO Launch date 2007-06-20
CEO & Executive Director Mr. Matthew Craig Kapusta CPA
Sector Healthcare
Industry Biotechnology
Full time employees 221
Full time employees 221

uniQure N.V. develops treatments for patients suffering from rare and other devastating diseases in the United States. The company offers HEMGENIX that allows people living with hemophilia B to produce factor IX, which can lower the risk of bleeding. Its lead product candidate is AMT-130, a gene therapy candidate, which is in Phase I/II clinical study for the treatment of Huntington's disease. The company also develops AMT-260, which is in Phase I/IIa clinical trial for the treatment of mesial temporal lobe epilepsy; AMT-162, which is in Phase I/IIa clinical trial to treat superoxide dismutase enzyme-amyotrophic lateral sclerosis; and AMT-191, an investigational gene therapy candidate which is in phase I/IIa clinical trial for the treatment of fabry disease. It has a licensing agreement with Apic Bio to develop, manufacture, and commercialize intrathecally administered investigational gene therapy for ALS caused by mutations in SOD-1; and development and commercial supply agreement with CLS Bhering. uniQure N.V. was founded in 1998 and is headquartered in Amsterdam, the Netherlands.