Rezolute Inc logo

Rezolute Inc(RZLT)

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ADVISORIES YOU CAN VERIFY
QUALITY SIGNAL
1-STAR RATING
PASS
LAST CLOSE
$3.9
09/25/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
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Upturn Advisory & Investor View for RZLT

09/25/2026: RZLT (1-star) is currently NOT-A-BUY. Pass it for now.

Rezolute Inc is a clinical-stage biopharmaceutical company focused on developing therapies for metabolic and rare diseases. Its primary value proposition rests on a pipeline of candidates, including RZ358 and RZ402, which aim to address significant patient needs in areas like congenital hyperinsulinism. While the company demonstrates promise through its proprietary research platforms, it is in a capital-intensive development phase with no commercialized products or consistent revenue. Key risks include binary clinical trial outcomes, potential for shareholder dilution, and intense competition. This stock may suit investors who are comfortable with the high-risk, high-reward nature of early-stage biotech and should closely monitor clinical trial results and capital management.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorMixed fitThe company offers high-risk, high-reward exposure typical of clinical-stage biotech but lacks current earnings growth.
Momentum investorMixed fitMomentum is often driven by clinical trial catalysts, making the stock volatile and dependent on news cycles.
Value investorWeak fitAs a loss-making clinical-stage company, traditional value metrics like P/E ratios are not applicable.
Dividend investorWeak fitThe company does not pay a dividend and prioritizes R&D spend over cash distribution.
Low-risk investorWeak fitThe high volatility and binary nature of clinical outcomes make this unsuitable for low-risk portfolios.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighClinical trial results can cause significant and sudden swings in stock price.
Valuation riskMedium / highValuations are speculative and based on projected future cash flows from drugs not yet approved.
Competition risk (Rare/Metabolic Drug Development)Medium / highMultiple companies compete to address similar patient populations with new therapeutic modalities.
Business qualityMediumThe company is in the process of proving its science rather than demonstrating an established commercial business model.
Dividend incomeLow / noneCapital is strictly reserved for drug development.
Execution riskHighFailure to achieve clinical endpoints or regulatory clearance would fundamentally impair the company's value.

Price Behavior

Rolling Over
PRICE PATH

Rolling Over

The price momentum is slowing down and beginning to turn downward.

Highly Choppy
PRICE STABILITY

Highly Choppy

The stock has experienced frequent, large price swings that make its near-term movement less predictable.

Analysis of Past Performance

Type Stock
Historic Profit -54.04%
Avg. Invested days 37
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 3.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 09/25/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
RZLT receives a 3-star rating, supported by solid analyst coverage. The rating is constrained by weak unit economics, soft quantitative characteristics, and weak price momentum.

Company Fundamentals

★★★★★
RZLT has moderate overall fundamentals (3 stars), with moderate financial health, moderate growth momentum, and strong ownership. In FY2026 versus FY2025, growth and ownership metrics are mixed: slightly negative earnings growth (-4.3%), soft cash generation (FCF margin 0.0%), slightly negative revenue growth (+0.0%).

Financial Health Rating

★★★★★
RZLT's financial health is supported by strong efficiency, including operating-expense and cost-of-revenue discipline (opex 0.0% of revenue). Profitability is weak (1 stars), which helps explain the 3-star overall score.

Growth Momentum Score

★★★★★
Free-cash-flow growth is RZLT's strongest growth driver at +6.4% FY2026 versus FY2025 (moderate, 3 stars). By comparison, while revenue growth (+0.0%, slightly negative) and earnings growth (-4.3%, slightly negative) hold the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 98.4% and approximately 62.8% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 10.10% supports management-shareholder alignment.

Top 5 Institutional Investors

Federated Hermes Inc 13.49%
RA Capital Management, LLC 9.53%
BlackRock Inc 6.56%
Opaleye Management Inc 6.54%
Balyasny Asset Management LLC 5.24%

Unit Economics (Per $1K Revenue)

★★★★★
RZLT generates approximately $-0 of gross profit, $-0 of operating income, and $-0 of free cash flow for every $1,000 of revenue. Based on FY2026 results. Strong cash conversion and healthy margins support the rating, although capital efficiency remains below the highest tier.

Economic Dimensions

★★★★★
Effective Tax Rate: 0.00%

Quantitative Style Profile

★★★★★
RZLT has a liquid, relatively low-volatility profile. Weak momentum is the primary drawback.

Style Classification

Quality Focused

Low VolatilitySmall / Mid Cap RiskShort Squeeze RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 377.22M USD
Price to earnings Ratio -
1Y Target Price 8.33
Price to earnings Ratio -
1Y Target Price 8.33
Volume (30-day avg) 1.5M shares
Beta 0.61
52 Weeks Range 1.07 - 11.46
Updated Date 09/27/2026
52 Weeks Range 1.07 - 11.46
Updated Date 09/27/2026
Dividends yield (FY) -
Basic EPS (TTM) -0.8

How Company Makes Money

Business areaWhat it includesRetail investor read
Clinical DevelopmentFuture potential milestone payments, licensing fees, and eventual product royalties.The company currently does not sell products and relies on external financing to fund the development of drugs that might eventually generate revenue.
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Valuation

Trailing PE -
Forward PE -
Enterprise Value 266.01M
Price to Sales(TTM) -
Enterprise Value 266.01M
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -0.01
Shares Outstanding 96.72M
Shares Floating 60.76M
Shares Outstanding 96.72M
Shares Floating 60.76M
Percent Insiders 10.1
Percent Institutions 98.37

Icon representing Upturn AI-generated SWOT analysis summary Upturn AI Summary

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Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

About Rezolute Inc

Exchange NASDAQ
Headquarters Redwood City, CA, United States
IPO Launch date 2014-05-01
CEO -
Sector Healthcare
Industry Biotechnology
Full time employees 58
Full time employees 58

Rezolute, Inc., a late-stage rare disease company, focuses developing therapies that treat refractory and debilitating hypoglycemia associated with various forms of hyperinsulinism (HI) in the United States. Its lead clinical asset is ersodetug, an intravenously administered human monoclonal antibody which is in Phase 3 clinical trial to treat tumor HI indication, as well as congenital HI. The company was formerly known as AntriaBio, Inc. and changed its name to Rezolute, Inc. in December 2017. Rezolute, Inc. was founded in 2010 and is headquartered in Redwood City, California.